Oncotarget

Vol 9, No 1

January 2, 2018

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About The Cover

The cover for issue 1 of Oncotarget features Figure 2, "Radiation-induced alternative splice events in the transcriptome and the translatome," from Wahba, et al.

Table of Contents

News

IDH1 R132H predicts sensitivity to Bcl-xL inhibition-mediated programmed cell death

IDH1 R132H predicts sensitivity to Bcl-xL inhibition-mediated programmed cell death

https://doi.org/10.18632/oncotarget.23399

Georg Karpel-Massler, Chiaki Tsuge Ishida,  and Markus D. Siegelin
1-2
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Priority Research Papers

Accelerated bottom-up drug design platform enables the discovery of novel stearoyl-CoA desaturase 1 inhibitors for cancer therapy

Accelerated bottom-up drug design platform enables the discovery of novel stearoyl-CoA desaturase 1 inhibitors for cancer therapy

https://doi.org/10.18632/oncotarget.21545

Christina A. von Roemeling, Thomas R. Caulfield, Laura Marlow, Ilah Bok, Jiang Wen, James L. Miller, Robert Hughes, Lori Hazlehurst, Anthony B. Pinkerton, Derek C. Radisky, Han W. Tun, Yon Son Betty Kim, Amy L. Lane,  and John A. Copland
3-20
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c-Myb and C/EBPβ regulate OPN and other senescence-associated secretory phenotype factors

c-Myb and C/EBPβ regulate OPN and other senescence-associated secretory phenotype factors

https://doi.org/10.18632/oncotarget.22940

Kevin C. Flanagan, Elise Alspach, Ermira Pazolli, Shankar Parajuli, Qihao Ren, Laura L. Arthur, Roberto Tapia,  and Sheila A. Stewart
21-36
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Research Papers: Gerotarget (Focus on Aging)

PINK1 suppresses alpha-synuclein-induced neuronal injury: a novel mechanism in protein phosphatase 2A activation

PINK1 suppresses alpha-synuclein-induced neuronal injury: a novel mechanism in protein phosphatase 2A activation

https://doi.org/10.18632/oncotarget.21554

Weiwei Yang, Xue Wang, Jia Liu, Chunli Duan, Ge Gao, Lingling Lu, Shun Yu,  and Hui Yang
37-53
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RCAN1 in the inverse association between Alzheimer’s disease and cancer

RCAN1 in the inverse association between Alzheimer’s disease and cancer

https://doi.org/10.18632/oncotarget.23094

Qiang Fu,  and Yili Wu
54-66
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Research Papers: Immunology

Urine anti-PLA2R antibody is a novel biomarker of idiopathic membranous nephropathy

Urine anti-PLA2R antibody is a novel biomarker of idiopathic membranous nephropathy

https://doi.org/10.18632/oncotarget.19859

Yu Wang, Yi-Xin He, Tian-Tian Diao, Shi-Yao Wei, Wen-Rui Qi, Cen-Cen Wang, Shu-Min Song, Min Bi, Chun-Mei Li, Cai-Xia Zhang, Yan-Pei Hou, Qiu-Ju Wei,  and Bing Li
67-74
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Peptide adjacent to glycosylation sites impacts immunogenicity of glycoconjugate vaccine

Peptide adjacent to glycosylation sites impacts immunogenicity of glycoconjugate vaccine

https://doi.org/10.18632/oncotarget.19944

Zhongrui Ma, Huajie Zhang, Peng George Wang, Xian-Wei Liu,  and Min Chen
75-82
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Genome-wide comparison of the protein-coding repertoire reveals fast evolution of immune-related genes in cephalochordates and Osteichthyes superclass

Genome-wide comparison of the protein-coding repertoire reveals fast evolution of immune-related genes in cephalochordates and Osteichthyes superclass

https://doi.org/10.18632/oncotarget.22749

Qi-Lin Zhang, Bin Xu, Xiu-Qiang Wang, Ming-Long Yuan,  and Jun-Yuan Chen
83-95
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Quantitative assessment of HLA-DQ gene polymorphisms with the development of hepatitis B virus infection, clearance, liver cirrhosis, and hepatocellular carcinoma

Quantitative assessment of HLA-DQ gene polymorphisms with the development of hepatitis B virus infection, clearance, liver cirrhosis, and hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.22941

Tao Xu, Anyou Zhu, Meiqun Sun, Jingzhu Lv, Zhongqing Qian, Xiaojing Wang, Ting Wang,  and Hongtao Wang
96-109
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Impaired autophagic flux and its related inflammation in patients with adult-onset Still’s disease

Impaired autophagic flux and its related inflammation in patients with adult-onset Still’s disease

https://doi.org/10.18632/oncotarget.23098

Chia-Wei Hsieh, Chun-Yu Chang, Yi-Ming Chen, Hsin-Hua Chen, Wei-Ting Hung, Ning-Rong Gung, Shiow-Jiuan Wey,  and Der-Yuan Chen
110-121
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Research Papers: Chromosome

Genetic identification and molecular modeling characterization reveal a novel PROM1 mutation in Stargardt4-like macular dystrophy

Genetic identification and molecular modeling characterization reveal a novel PROM1 mutation in Stargardt4-like macular dystrophy

https://doi.org/10.18632/oncotarget.22343

Saber Imani, Jingliang Cheng, Marzieh Dehghan Shasaltaneh, Chunli Wei, Lisha Yang, Shangyi Fu, Hui Zou, Md. Asaduzzaman Khan, Xianqin Zhang, Hanchun Chen, Dianzheng Zhang, Chengxia Duan, Hongbin Lv, Yumei Li, Rui Chen,  and Junjiang Fu
122-141
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Research Papers

The prognostic significance of nuclear expression of PHF2 and C/EBPα in clear cell renal cell carcinoma with consideration of adipogenic metabolic evolution

The prognostic significance of nuclear expression of PHF2 and C/EBPα in clear cell renal cell carcinoma with consideration of adipogenic metabolic evolution

https://doi.org/10.18632/oncotarget.19949

Jeong Hwan Park, Minsun Jung,  and Kyung Chul Moon
142-151
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Deguelin suppresses angiogenesis in human hepatocellular carcinoma by targeting HGF-c-Met pathway

Deguelin suppresses angiogenesis in human hepatocellular carcinoma by targeting HGF-c-Met pathway

https://doi.org/10.18632/oncotarget.22077

Ming Li, Xinfang Yu, Wei Li, Ting Liu, Gang Deng, Wenbin Liu, Haidan Liu,  and Feng Gao
152-166
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CUNR scoring system for the prediction of lateral lymph node metastasis in papillary thyroid carcinoma

CUNR scoring system for the prediction of lateral lymph node metastasis in papillary thyroid carcinoma

https://doi.org/10.18632/oncotarget.22772

Jianyong Lei, Gengpeng Li, Zhihui Li, RX Rong,  and Jingqiang Zhu
167-177
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Human DKK1 and human HSP70 fusion DNA vaccine induces an effective anti-tumor efficacy in murine multiple myeloma

Human DKK1 and human HSP70 fusion DNA vaccine induces an effective anti-tumor efficacy in murine multiple myeloma

https://doi.org/10.18632/oncotarget.23352

Ting-Ting Liu, Yang Wu,  and Ting Niu
178-191
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SOX9-PDK1 axis is essential for glioma stem cell self-renewal and temozolomide resistance

SOX9-PDK1 axis is essential for glioma stem cell self-renewal and temozolomide resistance

https://doi.org/10.18632/oncotarget.22773

Zhen Wang, Xiaoshan Xu, Nan Liu, Yingduan Cheng, Weilin Jin, Pengxing Zhang, Xin Wang, Hongwei Yang, Hui Liu,  and Yanyang Tu
192-204
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A method of respiratory phase optimization for better dose sparing of organs at risks: A validation study in patients with lung cancer

A method of respiratory phase optimization for better dose sparing of organs at risks: A validation study in patients with lung cancer

https://doi.org/10.18632/oncotarget.23353

Seong-Hee Kang, Siyong Kim, Dong-Su Kim, Tae-Ho Kim, So-Hyun Park, Dong-Seok Shin, Kyeong-Hyeon Kim, Min-Seok Cho, YeonSil Kim,  and Tae Suk Suh
205-216
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Squamous differentiation in pT1 bladder urothelial carcinoma predicts poor response for intravesical chemotherapy

Squamous differentiation in pT1 bladder urothelial carcinoma predicts poor response for intravesical chemotherapy

https://doi.org/10.18632/oncotarget.18563

Gang Li, Jieping Hu,  and Yuanjie Niu
217-223
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Alcohol and hepatitis virus-dysregulated lncRNAs as potential biomarkers for hepatocellular carcinoma

Alcohol and hepatitis virus-dysregulated lncRNAs as potential biomarkers for hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.22921

Hao Zheng, Pinxue Li, James G. Kwok, Avinaash Korrapati, Wei Tse Li, Yuanhao Qu, Xiao Qi Wang, Tatiana Kisseleva, Jessica Wang-Rodriguez,  and Weg M. Ongkeko
224-235
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Altered toll-like receptor expression and function in HPV-associated oropharyngeal carcinoma

Altered toll-like receptor expression and function in HPV-associated oropharyngeal carcinoma

https://doi.org/10.18632/oncotarget.18959

Priscila Lie Tobouti, Robert Bolt, Raghu Radhakrishnan, Suzana Cantanhede Orsini Machado Sousa,  and Keith D Hunter
236-248
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Three-dimensional tumor model mimics stromal – breast cancer cells signaling

Three-dimensional tumor model mimics stromal – breast cancer cells signaling

https://doi.org/10.18632/oncotarget.22922

Stephanie Lemmo Ham, Pradip Shahi Thakuri, Madison Plaster, Jun Li, Kathryn E. Luker, Gary D. Luker,  and Hossein Tavana
249-267
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Docking of THPDTPI: to explore P-selectin as a common target of anti-tumor, anti-thrombotic and anti-inflammatory agent

Docking of THPDTPI: to explore P-selectin as a common target of anti-tumor, anti-thrombotic and anti-inflammatory agent

https://doi.org/10.18632/oncotarget.19374

Haimei Zhu, Yuji Wang, Ce Song, Qiqi Feng, Jianhui Wu, Shurui Zhao, Lin Gui, Xiaoyi Zhang, Ming Zhao,  and Shiqi Peng
268-281
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Efficient inhibition of cervical cancer by dual drugs loaded in biodegradable thermosensitive hydrogel composites

Efficient inhibition of cervical cancer by dual drugs loaded in biodegradable thermosensitive hydrogel composites

https://doi.org/10.18632/oncotarget.22965

Shan Xu, XiaoBo Du, Gang Feng, Yu Zhang, Jie Li, Binwei Lin, LingLin Yang, ShaoZhi Fu,  and JingBo Wu
282-292
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Extracellular signal regulated kinase 5 and inflammasome in progression of mesothelioma

Extracellular signal regulated kinase 5 and inflammasome in progression of mesothelioma

https://doi.org/10.18632/oncotarget.22968

Joyce K. Thompson, Anurag Shukla, Alan L. Leggett, Phillip B. Munson, Jill M. Miller, Maximilian B. MacPherson, Stacie L. Beuschel, Harvey I. Pass,  and Arti Shukla
293-305
Abstract  |  PDF  |  HTML  |  Order a Reprint

Prognostic significance of E-cadherin and ZEB1 expression in intraductal papillary mucinous neoplasm

Prognostic significance of E-cadherin and ZEB1 expression in intraductal papillary mucinous neoplasm

https://doi.org/10.18632/oncotarget.23012

Ye Rim Chang, Taesung Park, Sung Hyo Park, Yong Kang Kim, Kyoung Bun Lee, Sun-Whe Kim,  and Jin-Young Jang
306-320
Abstract  |  PDF  |  HTML  |  Order a Reprint

MicroRNA-761 promotes the sensitivity of colorectal cancer cells to 5-Fluorouracil through targeting FOXM1

MicroRNA-761 promotes the sensitivity of colorectal cancer cells to 5-Fluorouracil through targeting FOXM1

https://doi.org/10.18632/oncotarget.20109

Shuguang Cao, Limiao Lin, Xuanping Xia,  and Hao Wu
321-331
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Low dose radiation prevents doxorubicin-induced cardiotoxicity

Low dose radiation prevents doxorubicin-induced cardiotoxicity

https://doi.org/10.18632/oncotarget.23013

Xin Jiang, Yaqiong Hong, Di Zhao, Xinxin Meng, Lijing Zhao, Yanwei Du, Zan Wang, Yan Zheng, Lu Cai,  and Hongyu Jiang
332-345
Abstract  |  PDF  |  HTML  |  Order a Reprint

Preclinical efficacy and biological effects of the oral proteasome inhibitor ixazomib in diffuse large B-cell lymphoma

Preclinical efficacy and biological effects of the oral proteasome inhibitor ixazomib in diffuse large B-cell lymphoma

https://doi.org/10.18632/oncotarget.20378

Wei Liu, Juan Chen, Archito T. Tamayo, Changgeng Ruan, Li Li, Shouhao Zhou, Chan Shen, Ken H. Young, Jason Westin, Richard E. Davis, Shimin Hu, Leonard J. Medeiros, Richard J. Ford,  and Lan V. Pham
346-360
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The inhibitory activity of gallic acid against DNA methylation: application of gallic acid on epigenetic therapy of human cancers

The inhibitory activity of gallic acid against DNA methylation: application of gallic acid on epigenetic therapy of human cancers

https://doi.org/10.18632/oncotarget.23015

Yui-Ping Weng, Pin-Feng Hung, Wen-Yen Ku, Chang-Yuan Chang, Bo-Han Wu, Ming-Han Wu, Jau-Ying Yao, Ji-Rui Yang,  and Chia-Huei Lee
361-374
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Iodine stimulates estrogen receptor singling and its systemic level is increased in surgical patients due to topical absorption

Iodine stimulates estrogen receptor singling and its systemic level is increased in surgical patients due to topical absorption

https://doi.org/10.18632/oncotarget.20633

Shaohua He, Bingchan Wang, Xiyi Lu, Suyu Miao, Fengming Yang, Theodore Zava, Qiang Ding, Shijiang Zhang, Jiayin Liu, David Zava,  and Yuenian Eric Shi
375-384
Abstract  |  PDF  |  HTML  |  Order a Reprint

A prognostic score model to determine which breast cancer patients with 1–3 positive lymph nodes after modified radical mastectomy should receive radiotherapy

A prognostic score model to determine which breast cancer patients with 1–3 positive lymph nodes after modified radical mastectomy should receive radiotherapy

https://doi.org/10.18632/oncotarget.21531

Dawei Chen, Haiyong Wang, Xinyu Song, Fang Shi, Li Kong,  and Jinming Yu
385-393
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MnTBAP therapy attenuates the downregulation of sodium transporters in obstructive kidney disease

MnTBAP therapy attenuates the downregulation of sodium transporters in obstructive kidney disease

https://doi.org/10.18632/oncotarget.23037

Mi Liu, Yangyang Zhu, Ying Sun, Zhaoying Wen, Songming Huang, Guixia Ding, Aihua Zhang, Zhanjun Jia,  and Yue Zhang
394-403
Abstract  |  PDF  |  HTML  |  Order a Reprint

HBXIP activates the PPARδ/NF-κB feedback loop resulting in cell proliferation

HBXIP activates the PPARδ/NF-κB feedback loop resulting in cell proliferation

https://doi.org/10.18632/oncotarget.23057

Qian Liu, Wenbin Lu, Chunxia Yang, Yue Wang, Wenjing Li, Ying Chu, Jianzhong Deng, Yongzhong Hou,  and Jianhua Jin
404-417
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

1,25-Dihydroxyvitamin D3 inhibits the proliferation of rat mesangial cells induced by high glucose via DDIT4

1,25-Dihydroxyvitamin D3 inhibits the proliferation of rat mesangial cells induced by high glucose via DDIT4

https://doi.org/10.18632/oncotarget.23063

Da-Peng Chen, Ye-Ping Ma, Li Zhuo, Zheng Zhang, Gu-Ming Zou, Yue Yang, Hong-Mei Gao,  and Wen-Ge Li
418-427
Abstract  |  PDF  |  HTML  |  Order a Reprint

Comparison of clinical and survival characteristics between prostate cancer patients of PSA-based screening and clinical diagnosis in China

Comparison of clinical and survival characteristics between prostate cancer patients of PSA-based screening and clinical diagnosis in China

https://doi.org/10.18632/oncotarget.20787

Libo Xu, Jinguo Wang, Baofeng Guo, Haixia Zhang, Kaichen Wang, Ding Wang, Chang Dai, Ling Zhang,  and Xuejian Zhao
428-441
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Utilizing glycine N-methyltransferasegene knockout mice as a model for identification of missing proteins in hepatocellular carcinoma

Utilizing glycine N-methyltransferasegene knockout mice as a model for identification of missing proteins in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.23064

Ming-Hui Yang, Wan-Jou Chen, Yaw-Syan Fu, Bin Huang, Wan-Chi Tsai, Yi-Ming Arthur Chen, Po-Chiao Lin, Cheng-Hui Yuan,  and Yu-Chang Tyan
442-452
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Transcriptome evolution from breast epithelial cells to basal-like tumors

Transcriptome evolution from breast epithelial cells to basal-like tumors

https://doi.org/10.18632/oncotarget.23065

Gabriel Santpere, Ana Alcaráz-Sanabria, Verónica Corrales-Sánchez, Atanasio Pandiella, Balázs Győrffy,  and Alberto Ocaña
453-463
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Exome sequencing reveals aberrant signalling pathways as hallmark of treatment-naive anal squamous cell carcinoma

Exome sequencing reveals aberrant signalling pathways as hallmark of treatment-naive anal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.23066

Wulfran Cacheux, Virginie Dangles-Marie, Etienne Rouleau, Julien Lazartigues, Elodie Girard, Adrien Briaux, Pascale Mariani, Sophie Richon, Sophie Vacher, Bruno Buecher, Marion Richard-Molard, Emmanuelle Jeannot, Nicolas Servant, Fereshteh Farkhondeh, Odette Mariani, Thomas Rio-Frio, Sergio Roman-Roman, Emmanuel Mitry, Ivan Bieche,  and Astrid Lièvre
464-476
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Homing of endogenous bone marrow mesenchymal stem cells to rat infarcted myocardium via ultrasound-mediated recombinant SDF-1α adenovirus in microbubbles

Homing of endogenous bone marrow mesenchymal stem cells to rat infarcted myocardium via ultrasound-mediated recombinant SDF-1α adenovirus in microbubbles

https://doi.org/10.18632/oncotarget.23068

Gaofeng Su, Liyun Liu, Lingjie Yang, Yuming Mu,  and Lina Guan
477-487
Abstract  |  PDF  |  HTML  |  Order a Reprint

Prognostic value of quantitative ctDNA levels in non small cell lung cancer patients

Prognostic value of quantitative ctDNA levels in non small cell lung cancer patients

https://doi.org/10.18632/oncotarget.22470

Mariano Provencio, María Torrente, Virginia Calvo, David Pérez-Callejo, Lourdes Gutiérrez, Fernando Franco, Clara Pérez-Barrios, Miguel Barquín, Ana Royuela, Francisco García-García, Coralia Bueno, Aranzazu Garcia-Grande, Carlos Camps, Bartomeu Massuti, Eduardo Sotomayor,  and Atocha Romero
488-494
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

In vitro and in vivo anti-leukemic effects of cladoloside C2 are mediated by activation of Fas/ceramide synthase 6/p38 kinase/ c-Jun NH2-terminal kinase/caspase-8

In vitro and in vivo anti-leukemic effects of cladoloside C2 are mediated by activation of Fas/ceramide synthase 6/p38 kinase/ c-Jun NH2-terminal kinase/caspase-8

https://doi.org/10.18632/oncotarget.23069

Seong-Hoon Yun, Eun-Hye Sim, Sang-Heum Han, Tae-Rang Kim, Mi-Ha Ju, Jin-Yeong Han, Jin-Sook Jeong, Sung-Hyun Kim, Alexandra S. Silchenko, Valentin A. Stonik,  and Joo-In Park
495-511
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

HDAC inhibitor PAC-320 induces G2/M cell cycle arrest and apoptosis in human prostate cancer

HDAC inhibitor PAC-320 induces G2/M cell cycle arrest and apoptosis in human prostate cancer

https://doi.org/10.18632/oncotarget.23070

Zhixiong Dong, Yang Yang, Shuxia Liu, Jun Lu, Baiqu Huang,  and Yu Zhang
512-523
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Allogeneic hematopoietic stem cell transplantation for relapsed acute myeloid leukemia in ETO positive with reduced-intensity conditioning

Allogeneic hematopoietic stem cell transplantation for relapsed acute myeloid leukemia in ETO positive with reduced-intensity conditioning

https://doi.org/10.18632/oncotarget.22612

Zhi Guo, Chen Xu,  and Hu Chen
524-538
Abstract  |  PDF  |  HTML  |  Order a Reprint

Loss of epithelium-specific GPx2 results in aberrant cell fate decisions during intestinal differentiation

Loss of epithelium-specific GPx2 results in aberrant cell fate decisions during intestinal differentiation

https://doi.org/10.18632/oncotarget.22640

Claudia Lennicke, Jette Rahn, Claudia Wickenhauser, Rudolf Lichtenfels, Andreas S. Müller, Ludger A. Wessjohann, Anna P. Kipp,  and Barbara Seliger
539-552
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

OTUD7B upregulation predicts a poor response to paclitaxel in patients with triple-negative breast cancer

OTUD7B upregulation predicts a poor response to paclitaxel in patients with triple-negative breast cancer

https://doi.org/10.18632/oncotarget.23074

Hui-Wen Chiu, Hui-Yu Lin, Ing-Jy Tseng, Michael Hsiao,  and Yuan-Feng Lin
553-565
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Pathway-focused PCR array profiling of CAL-27 cell with overexpressed ZNF750

Pathway-focused PCR array profiling of CAL-27 cell with overexpressed ZNF750

https://doi.org/10.18632/oncotarget.23075

Li Pan, Hongli Yang, Wenqiang Tang, Cong Xu, Shuangfeng Chen, Zhen Meng, Keyi Li,  and Haiying Chen
566-575
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Liver X receptors agonist promotes differentiation of rat bone marrow derived mesenchymal stem cells into dopaminergic neuron-like cells

Liver X receptors agonist promotes differentiation of rat bone marrow derived mesenchymal stem cells into dopaminergic neuron-like cells

https://doi.org/10.18632/oncotarget.23076

Oumei Cheng, Xiaoyan Tian, Ying Luo, Shaoshan Mai, Yang Yang, Shengnan Kuang, Qi Chen, Jie Ma, Beibei Chen, Rong Li, Lu Yang, Huan Li, Congli Hu, Jiahua Zhang, Zhihao Chen, Yuke Li, Hui Xia, Ying Xu,  and Junqing Yang
576-590
Abstract  |  PDF  |  HTML  |  Order a Reprint

Nicotine-enhanced stemness and epithelial-mesenchymal transition of human umbilical cord mesenchymal stem cells promote tumor formation and growth in nude mice

Nicotine-enhanced stemness and epithelial-mesenchymal transition of human umbilical cord mesenchymal stem cells promote tumor formation and growth in nude mice

https://doi.org/10.18632/oncotarget.22712

Tao Li, Jun Zhang, Jiahui Zhang, Nannan Zhang, Yang Zeng, Shengnan Tang, Zehua Tao, Xiying Qu, Jue Jia, Wei Zhu, Xiaochun Sun,  and Huabiao Chen
591-606
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Expression of ANO1/DOG1 is associated with shorter survival and progression of breast carcinomas

Expression of ANO1/DOG1 is associated with shorter survival and progression of breast carcinomas

https://doi.org/10.18632/oncotarget.23078

Jun Sang Bae, Jeong Yeol Park, See-Hyoung Park, Sang Hoon Ha, Ae Ri An, Sang Jae Noh, Keun Sang Kwon, Sung Hoo Jung, Ho Sung Park, Myoung Jae Kang,  and Kyu Yun Jang
607-621
Abstract  |  PDF  |  HTML  |  Order a Reprint

Development of suspension cell culture model to mimic circulating tumor cells

Development of suspension cell culture model to mimic circulating tumor cells

https://doi.org/10.18632/oncotarget.23079

Ji Young Park, Ae Lee Jeong, Hyun Jeong Joo, Sora Han, So-Hyun Kim, Hye-Youn Kim, Jong-Seok Lim, Myeong-Sok Lee, Hyung-Kyoon Choi,  and Young Yang
622-640
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

PD-L1 (CD274) and PD-L2 (PDCD1LG2) promoter methylation is associated with HPV infection and transcriptional repression in head and neck squamous cell carcinomas

PD-L1 (CD274) and PD-L2 (PDCD1LG2) promoter methylation is associated with HPV infection and transcriptional repression in head and neck squamous cell carcinomas

https://doi.org/10.18632/oncotarget.23080

Alina Franzen, Timo J. Vogt, Tim Müller, Jörn Dietrich, Andreas Schröck, Carsten Golletz, Peter Brossart, Friedrich Bootz, Jennifer Landsberg, Glen Kristiansen,  and Dimo Dietrich
641-650
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Progesterone inhibits contraction and increases TREK-1 potassium channel expression in late pregnant rat uterus

Progesterone inhibits contraction and increases TREK-1 potassium channel expression in late pregnant rat uterus

https://doi.org/10.18632/oncotarget.23084

Zongzhi Yin, Yun Li, Wenzhu He, Dan Li, Hongyan Li, Yuanyuan Yang, Bing Shen, Xi Wang, Yunxia Cao,  and Raouf A. Khalil
651-661
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Clinical validation of serum endocan (ESM-1) as a potential biomarker in patients with renal cell carcinoma

Clinical validation of serum endocan (ESM-1) as a potential biomarker in patients with renal cell carcinoma

https://doi.org/10.18632/oncotarget.23087

Kwang Hyun Kim, Hyung Ho Lee, Young Eun Yoon, Joon Chae Na, Sook Young Kim, Young In Cho, Sung Joon Hong,  and Woong Kyu Han
662-667
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C-MYC and BCL-2 mediate YAP-regulated tumorigenesis in OSCC

C-MYC and BCL-2 mediate YAP-regulated tumorigenesis in OSCC

https://doi.org/10.18632/oncotarget.23089

Xiyan Chen, Weiting Gu, Qi Wang, Xucheng Fu, Ying Wang, Xin Xu,  and Yong Wen
668-679
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PGK1 and GRP78 overexpression correlates with clinical significance and poor prognosis in Chinese endometrial cancer patients

PGK1 and GRP78 overexpression correlates with clinical significance and poor prognosis in Chinese endometrial cancer patients

https://doi.org/10.18632/oncotarget.23090

Suiqun Guo, Yanyi Xiao, Danqing Li, Qingping Jiang, Litong Zhu, Dan Lin, Huiping Jiang, Wei Chen, Lijing Wang, Chunhua Liu, Weiyi Fang,  and Li Lin
680-690
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Radiation-induced alternative transcripts as detected in total and polysome-bound mRNA

Radiation-induced alternative transcripts as detected in total and polysome-bound mRNA

https://doi.org/10.18632/oncotarget.21672

Amy Wahba, Michael C. Ryan, Uma T. Shankavaram, Kevin Camphausen,  and Philip J. Tofilon
691-705
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The dual PI3K/mTOR inhibitor dactolisib elicits anti-tumor activity in vitro and in vivo

The dual PI3K/mTOR inhibitor dactolisib elicits anti-tumor activity in vitro and in vivo

https://doi.org/10.18632/oncotarget.23091

Fei Shi, Jinying Zhang, Hongyu Liu, Liangliang Wu, Hongyu Jiang, Qiyan Wu, Tianyi Liu, Meiqing Lou,  and Hao Wu
706-717
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Chemopreventative celecoxib fails to prevent schwannoma formation or sensorineural hearing loss in genetically engineered murine model of neurofibromatosis type 2

Chemopreventative celecoxib fails to prevent schwannoma formation or sensorineural hearing loss in genetically engineered murine model of neurofibromatosis type 2

https://doi.org/10.18632/oncotarget.22002

Benjamin M. Wahle, Eric T. Hawley, Yongzheng He, Abbi E. Smith, Jin Yuan, Andi R. Masters, David R. Jones, Jeffrey R. Gehlhausen, Su-Jung Park, Simon J. Conway, D. Wade Clapp,  and Charles W. Yates
718-725
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Cooperation between ZEB2 and Sp1 promotes cancer cell survival and angiogenesis during metastasis through induction of survivin and VEGF

Cooperation between ZEB2 and Sp1 promotes cancer cell survival and angiogenesis during metastasis through induction of survivin and VEGF

https://doi.org/10.18632/oncotarget.23139

Dongjoon Ko,  and Semi Kim
726-742
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Organic cation transporter 3 mediates cisplatin and copper cross-resistance in hepatoma cells

Organic cation transporter 3 mediates cisplatin and copper cross-resistance in hepatoma cells

https://doi.org/10.18632/oncotarget.23142

Sarah Guttmann, Gursimran Chandhok, Sara Reinartz Groba, Christoph Niemietz, Vanessa Sauer, Amanda Gomes, Giuliano Ciarimboli, Uwe Karst, Andree Zibert,  and Hartmut H. Schmidt
743-754
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Jazf1 promotes prostate cancer progression by activating JNK/Slug

Jazf1 promotes prostate cancer progression by activating JNK/Slug

https://doi.org/10.18632/oncotarget.23146

Yonghun Sung, Song Park, Si Jun Park, Jain Jeong, Minjee Choi, Jinhee Lee, Wookbong Kwon, Soyoung Jang, Mee-Hyun Lee, Dong Joon Kim, Kangdong Liu, Sung-Hyun Kim, Jae-Ho Lee, Yun-Sok Ha, Tae Gyun Kwon, Sanggyu Lee, Zigang Dong, Zae Young Ryoo,  and Myoung Ok Kim
755-765
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Phase II study of rituximab given in conjunction with standard chemotherapy in primary central nervous system lymphoma (PCNSL): a trial of the ECOG-ACRIN cancer research group (E1F05)

Phase II study of rituximab given in conjunction with standard chemotherapy in primary central nervous system lymphoma (PCNSL): a trial of the ECOG-ACRIN cancer research group (E1F05)

https://doi.org/10.18632/oncotarget.22332

Lode J. Swinnen, Anne O'Neill, Philip H. Imus, Sachin Gujar, David Schiff, Lawrence R. Kleinberg, Ranjana H. Advani, Erin M. Dunbar, Dennis Moore,  and Stuart A. Grossman
766-773
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Thyroid cancer risk in the Swedish AMORIS study: the role of inflammatory biomarkers in serum

Thyroid cancer risk in the Swedish AMORIS study: the role of inflammatory biomarkers in serum

https://doi.org/10.18632/oncotarget.22891

Arunangshu Ghoshal, Hans Garmo, Rhonda Arthur, Paul Carroll, Lars Holmberg, Niklas Hammar, Ingmar Jungner, Håkan Malmström, Mats Lambe, Göran Walldius,  and Mieke Van Hemelrijck
774-782
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Down-regulation of long non-coding RNA ESCCAL_1 inhibits tumor growth of esophageal squamous cell carcinoma in a xenograft mouse model

Down-regulation of long non-coding RNA ESCCAL_1 inhibits tumor growth of esophageal squamous cell carcinoma in a xenograft mouse model

https://doi.org/10.18632/oncotarget.23153

Yuanbo Cui, Wei Wu, Pengju Lv, Jianying Zhang, Bingqing Bai,  and Wei Cao
783-790
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Folate receptor-α targeted near-infrared fluorescence imaging in high-risk endometrial cancer patients: a tissue microarray and clinical feasibility study

Folate receptor-α targeted near-infrared fluorescence imaging in high-risk endometrial cancer patients: a tissue microarray and clinical feasibility study

https://doi.org/10.18632/oncotarget.23155

Leonora S.F. Boogerd, Charlotte E.S. Hoogstins, Katja N. Gaarenstroom, Cornelis D. de Kroon, Jogchum J. Beltman, Tjalling Bosse, Ellen Stelloo, Jaap Vuyk, Philip S. Low, Jacobus Burggraaf,  and Alexander L. Vahrmeijer
791-801
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Propranolol enhanced the anti-tumor effect of sunitinib by inhibiting proliferation and inducing G0/G1/S phase arrest in malignant melanoma

Propranolol enhanced the anti-tumor effect of sunitinib by inhibiting proliferation and inducing G0/G1/S phase arrest in malignant melanoma

https://doi.org/10.18632/oncotarget.22696

Xinwei Kuang, Min Qi, Cong Peng, Chengfang Zhou, Juan Su, Weiqi Zeng, Hong Liu, Jianglin Zhang, Mingliang Chen, Minxue Shen, Xiaoyun Xie, Fangfang Li, Shuang Zhao, Qingling Li, Zhongling Luo, Junchen Chen, Juan Tao, Yijing He,  and Xiang Chen
802-811
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Efficient leukocyte depletion by a novel microfluidic platform enables the molecular detection and characterization of circulating tumor cells

Efficient leukocyte depletion by a novel microfluidic platform enables the molecular detection and characterization of circulating tumor cells

https://doi.org/10.18632/oncotarget.22549

Eva Obermayr, Elisabeth Maritschnegg, Christiane Agreiter, Nina Pecha, Paul Speiser, Samir Helmy-Bader, Sabine Danzinger, Michael Krainer, Christian Singer,  and Robert Zeillinger
812-823
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Frizzled-10 and cancer progression: Is it a new prognostic marker?

Frizzled-10 and cancer progression: Is it a new prognostic marker?

https://doi.org/10.18632/oncotarget.23159

Maria Principia Scavo, Livia Fucci, Lucia Caldarola, Anita Mangia, Amalia Azzariti, Giovanni Simone, Giampietro Gasparini,  and Silke Krol
824-830
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Recombinant rabies virus with the glycoprotein fused with a DC-binding peptide is an efficacious rabies vaccine

Recombinant rabies virus with the glycoprotein fused with a DC-binding peptide is an efficacious rabies vaccine

https://doi.org/10.18632/oncotarget.23160

Yachun Zhang, Ming Zhou, Yingying Li, Zhaochen Luo, Huanchun Chen, Min Cui, Zhen F. Fu,  and Ling Zhao
831-841
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FoxM1 is a promising candidate target in the treatment of breast cancer

FoxM1 is a promising candidate target in the treatment of breast cancer

https://doi.org/10.18632/oncotarget.23182

Xiao-Feng Lu, De Zeng, Wei-Quan Liang, Chun-Fa Chen, Shu-Ming Sun,  and Hao-Yu Lin
842-852
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Gli is activated and promotes epithelial-mesenchymal transition in human esophageal adenocarcinoma

Gli is activated and promotes epithelial-mesenchymal transition in human esophageal adenocarcinoma

https://doi.org/10.18632/oncotarget.22856

Lei Wang, Joy Q. Jin, Yong Zhou, Ziqiang Tian, David M. Jablons,  and Biao He
853-865
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Xanthohumol prevents dextran sulfate sodium-induced colitis via inhibition of IKKβ/NF-κB signaling in mice

Xanthohumol prevents dextran sulfate sodium-induced colitis via inhibition of IKKβ/NF-κB signaling in mice

https://doi.org/10.18632/oncotarget.23183

Jae-Min Cho, Sun-Mi Yun, Young-Ho Choi, Jinyuk Heo, Nam-Jung Kim, Seok-Ho Kim,  and Eun-Hee Kim
866-880
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Genetic variation in CDH13 gene was associated with non-small cell lung cancer (NSCLC): A population-based case-control study

Genetic variation in CDH13 gene was associated with non-small cell lung cancer (NSCLC): A population-based case-control study

https://doi.org/10.18632/oncotarget.22971

Yingfu Li, Chuanyin Li, Qianli Ma, Yu Zhang, Yueting Yao, Shuyuan Liu, Xinwen Zhang, Chao Hong, Fang Tan, Li Shi,  and Yufeng Yao
881-891
Abstract  |  PDF  |  HTML  |  Order a Reprint

Direct bilirubin levels are prognostic in non-small cell lung cancer

Direct bilirubin levels are prognostic in non-small cell lung cancer

https://doi.org/10.18632/oncotarget.23184

Ying-Jian Song, Xin-Huai Gao, Yong-Qing Hong,  and Li-Xin Wang
892-900
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Baicalin hydrate inhibits cancer progression in nasopharyngeal carcinoma by affecting genome instability and splicing

Baicalin hydrate inhibits cancer progression in nasopharyngeal carcinoma by affecting genome instability and splicing

https://doi.org/10.18632/oncotarget.22868

Weiwei Lai, Jiantao Jia, Bin Yan, Yiqun Jiang, Ying Shi, Ling Chen, Chao Mao, Xiaoli Liu, Haosheng Tang, Menghui Gao, Ya Cao, Shuang Liu,  and Yongguang Tao
901-914
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Recombinant methioninase (rMETase) is an effective therapeutic for BRAF-V600E-negative as well as -positive melanoma in patient-derived orthotopic xenograft (PDOX) mouse models

Recombinant methioninase (rMETase) is an effective therapeutic for BRAF-V600E-negative as well as -positive melanoma in patient-derived orthotopic xenograft (PDOX) mouse models

https://doi.org/10.18632/oncotarget.23185

Kei Kawaguchi, Kentaro Igarashi, Shukuan Li, Qinghong Han, Yuying Tan, Kentaro Miyake, Tasuku Kiyuna, Masuyo Miyake, Takashi Murakami, Bartosz Chmielowski, Scott D. Nelson, Tara A. Russell, Sarah M. Dry, Yunfeng Li5, Michiaki Unno, Fritz C. Eilber,  and Robert M. Hoffman
915-923
Abstract  |  PDF  |  HTML  |  Order a Reprint

Discovery of a FLT3 inhibitor LDD1937 as an anti-leukemic agent for acute myeloid leukemia

Discovery of a FLT3 inhibitor LDD1937 as an anti-leukemic agent for acute myeloid leukemia

https://doi.org/10.18632/oncotarget.23221

Hyo Jeong Lee, Jungeun Lee, Pyeonghwa Jeong, Jungil Choi, Juhwa Baek, Su Jin Ahn, Yeongyu Moon, Jeong Doo Heo, Young Hee Choi, Young-Won Chin, Yong-Chul Kim,  and Sun-Young Han
924-936
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Molecular mechanisms of cardioprotective effects mediated by transplanted cardiac ckit+ cells through the activation of an inflammatory hypoxia-dependent reparative response

Molecular mechanisms of cardioprotective effects mediated by transplanted cardiac ckit+ cells through the activation of an inflammatory hypoxia-dependent reparative response

https://doi.org/10.18632/oncotarget.22946

Giovanni Puddighinu, Domenico D'Amario, Eleonora Foglio, Melissa Manchi, Andrea Siracusano, Elena Pontemezzo, Martina Cordella, Francesco Facchiano, Laura Pellegrini, Antonella Mangoni, Marco Tafani, Filippo Crea, Antonia Germani, Matteo Antonio Russo,  and Federica Limana
937-957
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Association of DNA repair gene polymorphisms with the risk of radiation pneumonitis in lung cancer patients

Association of DNA repair gene polymorphisms with the risk of radiation pneumonitis in lung cancer patients

https://doi.org/10.18632/oncotarget.22982

Lehui Du, Wei Yu, Xiangkun Dai, Nana Zhao, Xiang Huang, Fang Tong, Fang Liu, Yurong Huang, Zhongjian Ju, Wei Yang, Xiaohu Cong, Chuanbin Xie, Xiaoliang Liu, Lanqing Liang, Yanan Han,  and Baolin Qu
958-968
Abstract  |  PDF  |  HTML  |  Order a Reprint

Genomic landscape of colitis-associated cancer indicates the impact of chronic inflammation and its stratification by mutations in the Wnt signaling

Genomic landscape of colitis-associated cancer indicates the impact of chronic inflammation and its stratification by mutations in the Wnt signaling

https://doi.org/10.18632/oncotarget.22867

Masashi Fujita, Nagahide Matsubara, Ikuo Matsuda, Kazuhiro Maejima, Ayako Oosawa, Tomoki Yamano, Akihiro Fujimoto, Mayuko Furuta, Kaoru Nakano, Aya Oku-Sasaki, Hiroko Tanaka, Yuichi Shiraishi, Raúl Nicolás Mateos, Kenta Nakai, Satoru Miyano, Naohiro Tomita, Seiichi Hirota, Hiroki Ikeuchi,  and Hidewaki Nakagawa
969-981
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prostaglandin receptor EP3 regulates cell proliferation and migration with impact on survival of endometrial cancer patients

Prostaglandin receptor EP3 regulates cell proliferation and migration with impact on survival of endometrial cancer patients

https://doi.org/10.18632/oncotarget.23140

Junyan Zhu, Fabian Trillsch, Doris Mayr, Christina Kuhn, Martina Rahmeh, Simone Hofmann, Marianne Vogel, Sven Mahner, Udo Jeschke,  and Viktoria von Schönfeldt
982-994
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Mitochondrial dysfunction activates lysosomal-dependent mitophagy selectively in cancer cells

Mitochondrial dysfunction activates lysosomal-dependent mitophagy selectively in cancer cells

https://doi.org/10.18632/oncotarget.23171

Thomas G. Biel,  and V. Ashutosh Rao
995-1011
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Splice variants of the endonucleases XPF and XPG contain residual DNA repair capabilities and could be a valuable tool for personalized medicine

Splice variants of the endonucleases XPF and XPG contain residual DNA repair capabilities and could be a valuable tool for personalized medicine

https://doi.org/10.18632/oncotarget.23105

Janin Lehmann, Steffen Schubert, Christina Seebode, Antje Apel, Andreas Ohlenbusch,  and Steffen Emmert
1012-1027
Abstract  |  PDF  |  HTML  |  Order a Reprint

SNHG16/miR-140-5p axis promotes esophagus cancer cell proliferation, migration and EMT formation through regulating ZEB1

SNHG16/miR-140-5p axis promotes esophagus cancer cell proliferation, migration and EMT formation through regulating ZEB1

https://doi.org/10.18632/oncotarget.23178

Kai Zhang, Jing Chen, Haizhu Song,  and Long-Bang Chen
1028-1040
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Phosphorylation of caspase-9 at Thr125 directs paclitaxel resistance in ovarian cancer

Phosphorylation of caspase-9 at Thr125 directs paclitaxel resistance in ovarian cancer

https://doi.org/10.18632/oncotarget.23133

Mi Ran Byun,  and Jin Woo Choi
1041-1047
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Long non-coding RNA GAS5 and ZFAS1 are prognostic markers involved in translation targeted by miR-940 in prostate cancer

Long non-coding RNA GAS5 and ZFAS1 are prognostic markers involved in translation targeted by miR-940 in prostate cancer

https://doi.org/10.18632/oncotarget.23254

Xin Chen, Chao Yang, Shengli Xie,  and Edwin Cheung
1048-1062
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Identification of human age-associated gene co-expressions in functional modules using liquid association

Identification of human age-associated gene co-expressions in functional modules using liquid association

https://doi.org/10.18632/oncotarget.23148

Jialiang Yang, Yufang Qin, Tiantian Zhang, Fayou Wang, Lihong Peng, Lijuan Zhu, Dawei Yuan, Pan Gao, Jujuan Zhuang, Zhongyang Zhang, Jun Wang,  and Yun Fang
1063-1074
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MiR-27a as a predictor for the activation of hepatic stellate cells and hepatitis B virus-induced liver cirrhosis

MiR-27a as a predictor for the activation of hepatic stellate cells and hepatitis B virus-induced liver cirrhosis

https://doi.org/10.18632/oncotarget.23262

Hui Zhang, Xiu-Li Yan, Xin-Xin Guo, Miao-Juan Shi, Yi-Yu Lu, Qian-Mei Zhou, Qi-long Chen, Yi-Yang Hu, Lie-Ming Xu, Shuang Huang,  and Shi-Bing Su
1075-1090
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

CONCORD biomarker prediction for novel drug introduction to different cancer types

CONCORD biomarker prediction for novel drug introduction to different cancer types

https://doi.org/10.18632/oncotarget.23124

Youngchul Kim, Patrick M. Dillon, Taesung Park,  and Jae K. Lee
1091-1106
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Elevated transgelin/TNS1 expression is a potential biomarker in human colorectal cancer

Elevated transgelin/TNS1 expression is a potential biomarker in human colorectal cancer

https://doi.org/10.18632/oncotarget.23275

Huimin Zhou, Yiming Zhang, Lihao Wu, Wenrui Xie, Lan Li, Yu Yuan, Yu Chen, Ying Lin,  and Xinxiang He
1107-1113
Abstract  |  PDF  |  HTML  |  Order a Reprint

Changes in metabolism affect expression of ABC transporters through ERK5 and depending on p53 status

Changes in metabolism affect expression of ABC transporters through ERK5 and depending on p53 status

https://doi.org/10.18632/oncotarget.23305

Sana Belkahla, Abrar Ul Haq Khan, Delphine Gitenay, Catherine Alexia, Claire Gondeau, Dang-Nghiem Vo, Stefania Orecchioni, Giovanna Talarico, Francesco Bertolini, Guillaume Cartron, Javier Hernandez, Martine Daujat-Chavanieu, Nerea Allende-Vega,  and Martin Villalba Gonzalez
1114-1129
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Mechanism of action and efficacy of LY2109761---a TGF-β receptor inhibitor, targeting tumor microenvironment in liver cancer after TACE

Mechanism of action and efficacy of LY2109761---a TGF-β receptor inhibitor, targeting tumor microenvironment in liver cancer after TACE

https://doi.org/10.18632/oncotarget.23193

Xiaojun He, Xiaopeng Guo, Hongsen Zhang, Xiangchuang Kong, Fan Yang,  and Chuansheng Zheng
1130-1142
Abstract  |  PDF  |  HTML  |  Order a Reprint

CCAR2 negatively regulates IL-8 production in cervical cancer cells

CCAR2 negatively regulates IL-8 production in cervical cancer cells

https://doi.org/10.18632/oncotarget.23199

Wootae Kim, Jaehyuk Pyo, Byeong-Joo Noh, Joo-Won Jeong, Juhie Lee,  and Ja-Eun Kim
1143-1155
Abstract  |  PDF  |  HTML  |  Order a Reprint

Downregulation of long non-coding RNA LET predicts poor prognosis and increases Notch signaling in non-small cell lung cancer

Downregulation of long non-coding RNA LET predicts poor prognosis and increases Notch signaling in non-small cell lung cancer

https://doi.org/10.18632/oncotarget.23452

Shengwen Li, Hui Zhao, Jianqiang Li, Aizheng Zhang,  and Haibin Wang
1156-1168
Abstract  |  PDF  |  HTML  |  Order a Reprint

Estrogen/ERα signaling axis participates in osteoblast maturation via upregulating chromosomal and mitochondrial complex gene expressions

Estrogen/ERα signaling axis participates in osteoblast maturation via upregulating chromosomal and mitochondrial complex gene expressions

https://doi.org/10.18632/oncotarget.23453

Pei-I Lin, Yu-Ting Tai, Wing P. Chan, Yi-Ling Lin, Mei-Hsiu Liao,  and Ruei-Ming Chen
1169-1186
Abstract  |  PDF  |  HTML  |  Order a Reprint

Exosomes released by metabotropic glutamate receptor 1 (GRM1) expressing melanoma cells increase cell migration and invasiveness

Exosomes released by metabotropic glutamate receptor 1 (GRM1) expressing melanoma cells increase cell migration and invasiveness

https://doi.org/10.18632/oncotarget.23455

Allison L. Isola, Kevinn Eddy, Krzysztof Zembrzuski, James S. Goydos,  and Suzie Chen
1187-1199
Abstract  |  PDF  |  HTML  |  Order a Reprint

No differences in brain microstructure between young KIBRA-C carriers and non-carriers

No differences in brain microstructure between young KIBRA-C carriers and non-carriers

https://doi.org/10.18632/oncotarget.23348

Li Hu, Qunxing Xu, Jizhen Li, Feifei Wang, Xinghua Xu, Zhiyuan Sun, Xiangxing Ma, Yong Liu, Qing Wang,  and Dawei Wang
1200-1209
Abstract  |  PDF  |  HTML  |  Order a Reprint

KSHV LANA upregulates the expression of epidermal growth factor like domain 7 to promote angiogenesis

KSHV LANA upregulates the expression of epidermal growth factor like domain 7 to promote angiogenesis

https://doi.org/10.18632/oncotarget.23456

Suhani Thakker, Roxanne C. Strahan, Alexandra N. Scurry, Timsy Uppal,  and Subhash C. Verma
1210-1228
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Molecular regulation of ERK5 in development of diabetic retinopathy

Molecular regulation of ERK5 in development of diabetic retinopathy

https://doi.org/10.18632/oncotarget.23392

Qi Zhao, Lin Wang, Yuan Sun,  and Xiao-Xia Wang
1229-1236
Abstract  |  PDF  |  HTML  |  Order a Reprint

Meta-Analysis

High mobility group protein A2 overexpression indicates poor prognosis for cancer patients: a meta-analysis

High mobility group protein A2 overexpression indicates poor prognosis for cancer patients: a meta-analysis

https://doi.org/10.18632/oncotarget.23085

Dan Nie, Lingping Zhang, Qian Guo,  and Xiguang Mao
1237-1247
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Chinese C allele carriers of the ERCC5 rs1047768 polymorphism are more sensitive to platinum-based chemotherapy: a meta-analysis

Chinese C allele carriers of the ERCC5 rs1047768 polymorphism are more sensitive to platinum-based chemotherapy: a meta-analysis

https://doi.org/10.18632/oncotarget.18981

Meizhen Xu, Yina Liu, Dan Li, Xuelin Wang, Shuang Liang, Gaochuan Zhang,  and Xiaoqin Yang
1248-1256
Abstract  |  PDF  |  HTML  |  Order a Reprint

The prognostic value of NRF2 in solid tumor patients: a meta-analysis

The prognostic value of NRF2 in solid tumor patients: a meta-analysis

https://doi.org/10.18632/oncotarget.19838

Lingling Wang, Chunze Zhang, Litao Qin, Jingyue Xu, Xiaobo Li, Wenhong Wang, Lingqin Kong, Taizhen Zhou,  and Xichuan Li
1257-1265
Abstract  |  PDF  |  HTML  |  Order a Reprint

Serum levels of adipokines and cytokines in psoriasis patients: a systematic review and meta-analysis

Serum levels of adipokines and cytokines in psoriasis patients: a systematic review and meta-analysis

https://doi.org/10.18632/oncotarget.22260

Fan Bai, Wen Zheng, Yan Dong, Juan Wang, Malgorzata A. Garstka, Ruilian Li, Jingang An,  and Huiqun Ma
1266-1278
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic and clinicopathological significance of microRNA-494 overexpression in cancers: a meta-analysis

Prognostic and clinicopathological significance of microRNA-494 overexpression in cancers: a meta-analysis

https://doi.org/10.18632/oncotarget.22633

Zhenxian Xiang, Min Sun, Zewei Yuan, Chunxiao Zhang, Jun Jiang, Sihao Huang,  and Bin Xiong
1279-1290
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Association between hypertensive disorders of pregnancy and risk of autism in offspring: a systematic review and meta-analysis of observational studies

Association between hypertensive disorders of pregnancy and risk of autism in offspring: a systematic review and meta-analysis of observational studies

https://doi.org/10.18632/oncotarget.23030

Ruo-Ting Xu, Qing-Xian Chang, Qi-Qiong Wang, Jian Zhang, Lai-Xin Xia, Nanbert Zhong, Yan-Hong Yu, Mei Zhong,  and Qi-Tao Huang
1291-1301
Abstract  |  PDF  |  HTML  |  Order a Reprint

Clinical Research Papers

TNFR/TNF-α signaling pathway regulates apoptosis of alveolar macrophages in coal workers' pneumoconiosis

TNFR/TNF-α signaling pathway regulates apoptosis of alveolar macrophages in coal workers' pneumoconiosis

https://doi.org/10.18632/oncotarget.18921

Qing-Zeng Qian, Xiang-Ke Cao, Hai-Yan Liu, Guo-Ying Zheng, Qing-Qiang Qian,  and Fu-Hai Shen
1302-1310
Abstract  |  PDF  |  HTML  |  Order a Reprint

Mid-arm muscle circumference as a substantial factor against mortality among people with elevated gamma gaps

Mid-arm muscle circumference as a substantial factor against mortality among people with elevated gamma gaps

https://doi.org/10.18632/oncotarget.19372

Yuan-Ping Chao, Yi-Fen Lai, Tung-Wei Kao, Tao-Chun Peng, Yuan-Yung Lin, Mu-Tsun Shih, Wei-Liang Chen,  and Li-Wei Wu
1311-1325
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Reviews

3D modeling of cancer stem cell niche

3D modeling of cancer stem cell niche

https://doi.org/10.18632/oncotarget.19847

Jun He, Li Xiong, Qinglong Li, Liangwu Lin, Xiongying Miao, Shichao Yan, Zhangyong Hong, Leping Yang, Yu Wen,  and Xiyun Deng
1326-1345
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LGR5 and LGR6 in stem cell biology and ovarian cancer

LGR5 and LGR6 in stem cell biology and ovarian cancer

https://doi.org/10.18632/oncotarget.20178

Adam J. Schindler, Arisa Watanabe,  and Stephen B. Howell
1346-1355
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Equine infectious anemia virus in China

Equine infectious anemia virus in China

https://doi.org/10.18632/oncotarget.20381

Hua-Nan Wang, Dan Rao, Xian-Qiu Fu, Ming-Ming Hu,  and Jian-Guo Dong
1356-1364
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Exploring the molecular aspects associated with testicular germ cell tumors: a review

Exploring the molecular aspects associated with testicular germ cell tumors: a review

https://doi.org/10.18632/oncotarget.22373

Gaetano Facchini, Sabrina Rossetti, Carla Cavaliere, Carmine D’Aniello, Rossella Di Franco, Gelsomina Iovane, Giovanni Grimaldi, Raffaele Piscitelli, Paolo Muto, Gerardo Botti, Sisto Perdonà, Bianca Maria Veneziani, Massimiliano Berretta,  and Micaela Montanari
1365-1379
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Drug resistance related to aberrant glycosylation in colorectal cancer

Drug resistance related to aberrant glycosylation in colorectal cancer

https://doi.org/10.18632/oncotarget.22377

Ninon Very, Tony Lefebvre,  and Ikram El Yazidi-Belkoura
1380-1402
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Current research on head and neck cancer-associated long noncoding RNAs

Current research on head and neck cancer-associated long noncoding RNAs

https://doi.org/10.18632/oncotarget.22608

Wei Song, Yimin Sun, Jie Lin,  and Xiaoqin Bi
1403-1425
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LncRNAs regulate cancer metastasis via binding to functional proteins

LncRNAs regulate cancer metastasis via binding to functional proteins

https://doi.org/10.18632/oncotarget.22840

Liting Yang, Yanyan Tang, Fang Xiong, Yi He, Fang Wei, Shanshan Zhang, Can Guo, Bo Xiang, Ming Zhou, Ni Xie, Xiaoling Li, Yong Li, Guiyuan Li, Wei Xiong,  and Zhaoyang Zeng
1426-1443
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Circular RNAs: clinical relevance in cancer

Circular RNAs: clinical relevance in cancer

https://doi.org/10.18632/oncotarget.22846

Zhijie Xu, Yuanliang Yan, Shuangshuang Zeng, Shuang Dai, Xi Chen, Jie Wei,  and Zhicheng Gong
1444-1460
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Troponin through the looking-glass: emerging roles beyond regulation of striated muscle contraction

Troponin through the looking-glass: emerging roles beyond regulation of striated muscle contraction

https://doi.org/10.18632/oncotarget.22879

Jamie R. Johnston, P. Bryant Chase,  and Jose Renato Pinto
1461-1482
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Protein dysregulation in graft versus host disease

Protein dysregulation in graft versus host disease

https://doi.org/10.18632/oncotarget.23276

Liren Qian, Delia Dima, Cristian Berce, Yu Liu, Ioana Rus, Lajos-Zsolt Raduly, Yi Liu, Bobe Petrushev, Ioana Berindan-Neagoe, Alexandru Irimie, Alina Tanase, Ancuta Jurj, Jianliang Shen,  and Ciprian Tomuleasa
1483-1491
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