Oncotarget

Vol 8, No 67

December 19, 2017

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About The Cover

The cover for issue 67 of Oncotarget features Figure 5, "Expression of nominated siRNA hits in CRPC tumors, primary tumors, and benign prostate samples," from King, et al.

Table of Contents

Editorial

Chemotherapy-induced metastasis in breast cancer

Chemotherapy-induced metastasis in breast cancer

https://doi.org/10.18632/oncotarget.22717

George S. Karagiannis, John S. Condeelis,  and Maja H. Oktay
110733-110734
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What is changing in the adjuvant treatment of melanoma?

What is changing in the adjuvant treatment of melanoma?

https://doi.org/10.18632/oncotarget.22988

Paolo A. Ascierto, Giuseppe Palmieri,  and Helen Gogas
110735-110736
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Elongation vs stalling: place your BET

Elongation vs stalling: place your BET

https://doi.org/10.18632/oncotarget.22989

Elisa Donato, Ottavio Croci,  and Stefano Campaner
110737-110738
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Capecitabine for primary breast cancer

Capecitabine for primary breast cancer

https://doi.org/10.18632/oncotarget.22990

Masakazu Toi, Norikazu Masuda,  and Soo-Jung Lee
110739-110740
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Biomarkers in colorectal cancer screening

Biomarkers in colorectal cancer screening

https://doi.org/10.18632/oncotarget.22991

Katarzyna Schab, Aleksandra Tańska,  and Maciej Smutek
110741-110742
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Research Papers

The small molecule SI113 synergizes with mitotic spindle poisons in arresting the growth of human glioblastoma multiforme

The small molecule SI113 synergizes with mitotic spindle poisons in arresting the growth of human glioblastoma multiforme

https://doi.org/10.18632/oncotarget.22500

Claudia Abbruzzese, Giada Catalogna, Enzo Gallo, Simona di Martino, Anna M. Mileo, Mariantonia Carosi, Vincenzo Dattilo, Silvia Schenone, Francesca Musumeci, Patrizia Lavia, Nicola Perrotti, Rosario Amato,  and Marco G. Paggi
110743-110755
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Cymbopogon citratus and Camellia sinensis extracts selectively induce apoptosis in cancer cells and reduce growth of lymphoma xenografts in vivo

Cymbopogon citratus and Camellia sinensis extracts selectively induce apoptosis in cancer cells and reduce growth of lymphoma xenografts in vivo

https://doi.org/10.18632/oncotarget.22502

Cory Philion, Dennis Ma, Ivan Ruvinov, Fadi Mansour, Christopher Pignanelli, Megan Noel, Ammar Saleem, John Arnason, Mark Rodrigues, Inderpal Singh, Jesse Ropat,  and Siyaram Pandey
110756-110773
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Apatinib alone or combined with radiotherapy in metastatic prostate cancer: Results from a pilot, multicenter study

Apatinib alone or combined with radiotherapy in metastatic prostate cancer: Results from a pilot, multicenter study

https://doi.org/10.18632/oncotarget.22719

Feng Zhao, Wei Tian, Ming Zeng, Jianling Xia, Honglin Hu, Xinbao Hao, Liangfu Han, Hao Liu, Yangke He, Xueqiang Zhu, Liang Liang, Rui Ao, Min Wei, Lili Deng,  and Yuquan Wei
110774-110784
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MiR-19 regulates the proliferation and invasion of glioma by RUNX3 via β-catenin/Tcf-4 signaling

MiR-19 regulates the proliferation and invasion of glioma by RUNX3 via β-catenin/Tcf-4 signaling

https://doi.org/10.18632/oncotarget.22720

Jikui Sun, Zhifan Jia, Banban Li, Anling Zhang, Guangxiu Wang, Peiyu Pu, Zhijuan Chen, Zengguang Wang,  and Weidong Yang
110785-110796
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Altered GNAS imprinting due to folic acid deficiency contributes to poor embryo development and may lead to neural tube defects

Altered GNAS imprinting due to folic acid deficiency contributes to poor embryo development and may lead to neural tube defects

https://doi.org/10.18632/oncotarget.22731

Li Wang, Shaoyan Chang, Zhen Wang, Shan Wang, Junsheng Huo, Gangqiang Ding, Rui Li, Chi Liu, Shaofang Shangguan, Xiaolin Lu, Ting Zhang, Zhiyong Qiu,  and Jianxin Wu
110797-110810
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Survival prediction of kidney renal papillary cell carcinoma by comprehensive LncRNA characterization

Survival prediction of kidney renal papillary cell carcinoma by comprehensive LncRNA characterization

https://doi.org/10.18632/oncotarget.22732

Huihua Lan, Jianghui Zeng, Gang Chen,  and Huayi Huang
110811-110829
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Yonsei criteria: a clinical reflection of stage I left-sided pancreatic cancer

Yonsei criteria: a clinical reflection of stage I left-sided pancreatic cancer

https://doi.org/10.18632/oncotarget.22734

Jae Uk Chong, Sung Hyun Kim, Ho Kyoung Hwang, Chang Moo Kang,  and Woo Jung Lee
110830-110836
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EYA2 promotes lung cancer cell proliferation by downregulating the expression of PTEN

EYA2 promotes lung cancer cell proliferation by downregulating the expression of PTEN

https://doi.org/10.18632/oncotarget.22860

Zhaoming Li, Ran Qiu, Xia Qiu,  and Tian Tian
110837-110848
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A novel messenger RNA signature as a prognostic biomarker for predicting relapse in pancreatic ductal adenocarcinoma

A novel messenger RNA signature as a prognostic biomarker for predicting relapse in pancreatic ductal adenocarcinoma

https://doi.org/10.18632/oncotarget.22861

Guodong Shi, Jingjing Zhang, Zipeng Lu, Dongfang Liu, Yang Wu, Pengfei Wu, Jie Yin, Hao Yuan, Qicong Zhu, Lei Chen, Yue Fu, Yunpeng Peng, Yan Wang, Kuirong Jiang,  and Yi Miao
110849-110860
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A functional polymorphism of SSBP1 gene predicts prognosis and response to chemotherapy in resected gastric cancer patients

A functional polymorphism of SSBP1 gene predicts prognosis and response to chemotherapy in resected gastric cancer patients

https://doi.org/10.18632/oncotarget.22864

Qiuchen Li, Falin Qu, Renli Li, Xianli He, Yulong Zhai, Weigang Chen,  and Yong Zheng
110861-110876
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Role and regulation of Yap in KrasG12D-induced lung cancer

Role and regulation of Yap in KrasG12D-induced lung cancer

https://doi.org/10.18632/oncotarget.22865

Yaopan Mao, Shuguo Sun,  and Kenneth D. Irvine
110877-110889
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Chitosan composite scaffold combined with bone marrow-derived mesenchymal stem cells for bone regeneration: in vitro and in vivo evaluation

Chitosan composite scaffold combined with bone marrow-derived mesenchymal stem cells for bone regeneration: in vitro and in vivo evaluation

https://doi.org/10.18632/oncotarget.22917

Shengqi Zang, Lei Zhu, Kefu Luo, Rui Mu, Feng Chen, Xiaocui Wei, Xiaodong Yan, Biyao Han, Xiaolei Shi, Qintao Wang,  and Lei Jin
110890-110903
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The novel ATM inhibitor (AZ31) enhances antitumor activity in patient derived xenografts that are resistant to irinotecan monotherapy

The novel ATM inhibitor (AZ31) enhances antitumor activity in patient derived xenografts that are resistant to irinotecan monotherapy

https://doi.org/10.18632/oncotarget.22920

Justin Greene, Anna Nguyen, Stacey M. Bagby, Gemma N. Jones, WM. Tai, Kevin S. Quackenbush, Anna Schreiber, Wells A. Messersmith, Kalpana M. Devaraj, Patrick Blatchford, S. Gail Eckhardt, Elaine B. Cadogan, Gareth D. Hughes, Aaron Smith, Todd M. Pitts,  and John J. Arcaroli
110904-110913
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Evaluating the bias of circRNA predictions from total RNA-Seq data

Evaluating the bias of circRNA predictions from total RNA-Seq data

https://doi.org/10.18632/oncotarget.22972

Jinzeng Wang, Kang Liu, Ya Liu, Qi Lv, Fan Zhang,  and Haiyun Wang
110914-110921
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Dual SIRT1 expression patterns strongly suggests its bivalent role in human breast cancer

Dual SIRT1 expression patterns strongly suggests its bivalent role in human breast cancer

https://doi.org/10.18632/oncotarget.23006

Khaldoun Rifaï, Gaëlle Judes, Mouhamed Idrissou, Marine Daures, Yves-Jean Bignon, Frédérique Penault-Llorca,  and Dominique Bernard-Gallon
110922-110930
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High-resolution microbiome profiling uncovers Fusobacterium nucleatum, Lactobacillus gasseri/johnsonii, and Lactobacillus vaginalis associated to oral and oropharyngeal cancer in saliva from HPV positive and HPV negative patients treated with surgery and chemo-radiation

High-resolution microbiome profiling uncovers Fusobacterium nucleatum, Lactobacillus gasseri/johnsonii, and Lactobacillus vaginalis associated to oral and oropharyngeal cancer in saliva from HPV positive and HPV negative patients treated with surgery and chemo-radiation

https://doi.org/10.18632/oncotarget.20677

Rafael Guerrero-Preston, James Robert White, Filipa Godoy-Vitorino, Arnold Rodríguez Hilario, Kelvin Navarro, Herminio González, Christina Michailidi, Anne Jedlicka, Sierra Canapp, Jessica Bondy, Amanda Dziedzic, Barbara Mora Lagos, Gustavo Rivera-Alvarez, Carmen Ili-Gangas, Priscilla Brebi-Mieville, William Westra, Wayne Koch, Hyunseok Kang, Luigi Marchionni, Young Kim,  and David Sidransky
110931-110948
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Selenium suppresses inflammation by inducing microRNA-146a in Staphylococcus aureus-infected mouse mastitis model

Selenium suppresses inflammation by inducing microRNA-146a in Staphylococcus aureus-infected mouse mastitis model

https://doi.org/10.18632/oncotarget.20740

Weijing Sun, Qi Wang, Yingfang Guo, Yifan Zhao, Xinying Wang, Zhenbiao Zhang, Ganzhen Deng,  and Mengyao Guo
110949-110964
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Increased efficacy of metformin corresponds to differential metabolic effects in the ovarian tumors from obese versus lean mice

Increased efficacy of metformin corresponds to differential metabolic effects in the ovarian tumors from obese versus lean mice

https://doi.org/10.18632/oncotarget.20754

Jianjun Han, Weiya Z. Wysham, Yan Zhong, Hui Guo, Lu Zhang, Kim M. Malloy, Hallum K. Dickens, Gene Huh, Douglas Lee, Liza Makowski, Chunxiao Zhou,  and Victoria L. Bae-Jump
110965-110982
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Analyzing the influence of kinase inhibitors on DNA repair by differential proteomics of chromatin-interacting proteins and nuclear phospho-proteins

Analyzing the influence of kinase inhibitors on DNA repair by differential proteomics of chromatin-interacting proteins and nuclear phospho-proteins

https://doi.org/10.18632/oncotarget.22424

Lisa Gleißner, Marcel Kwiatkowski, Laura Myllynen, Pascal Steffen, Cordula Petersen, Kai Rothkamm, Hartmut Schlüter,  and Malte Kriegs
110983-110993
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C3G promotes a selective release of angiogenic factors from activated mouse platelets to regulate angiogenesis and tumor metastasis

C3G promotes a selective release of angiogenic factors from activated mouse platelets to regulate angiogenesis and tumor metastasis

https://doi.org/10.18632/oncotarget.22339

Víctor Martín-Granado, Sara Ortiz-Rivero, Rita Carmona, Sara Gutiérrez-Herrero, Mario Barrera, Laura San-Segundo, Celia Sequera, Pedro Perdiguero, Francisco Lozano, Francisco Martín-Herrero, José Ramón González-Porras, Ramón Muñoz-Chápuli, Almudena Porras,  and Carmen Guerrero
110994-111011
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CXCR4-expressing Mist1+ progenitors in the gastric antrum contribute to gastric cancer development

CXCR4-expressing Mist1+ progenitors in the gastric antrum contribute to gastric cancer development

https://doi.org/10.18632/oncotarget.22451

Kosuke Sakitani, Yoku Hayakawa, Huan Deng, Hiroshi Ariyama, Hiroto Kinoshita, Mitsuru Konishi, Satoshi Ono, Nobumi Suzuki, Sozaburo Ihara, Zhengchuan Niu, Woosook Kim, Takayuki Tanaka, Haibo Liu, Xiaowei Chen, Yagnesh Tailor, James G. Fox, Stephen F. Konieczny, Hiroshi Onodera, Antonia R. Sepulveda, Samuel Asfaha, Yoshihiro Hirata, Daniel L. Worthley, Kazuhiko Koike,  and Timothy C. Wang
111012-111025
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Prexasertib, a cell cycle checkpoint kinases 1 and 2 inhibitor, increases in vitro toxicity of PARP inhibition by preventing Rad51 foci formation in BRCA wild type high-grade serous ovarian cancer

Prexasertib, a cell cycle checkpoint kinases 1 and 2 inhibitor, increases in vitro toxicity of PARP inhibition by preventing Rad51 foci formation in BRCA wild type high-grade serous ovarian cancer

https://doi.org/10.18632/oncotarget.22195

Ethan Brill, Takuhei Yokoyama, Jayakumar Nair, Minshu Yu, Yeong-Ran Ahn,  and Jung-Min Lee
111026-111040
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ABCB1 3435TT and ABCG2 421CC genotypes were significantly associated with longer progression-free survival in Chinese breast cancer patients

ABCB1 3435TT and ABCG2 421CC genotypes were significantly associated with longer progression-free survival in Chinese breast cancer patients

https://doi.org/10.18632/oncotarget.22201

Wanjun Li, Dan Zhang, Fen Du, Xuemei Xing, Ying Wu, Dong Xiao, Ming Liang, Zhigang Fan, Peng Zhao, Tao Liu,  and Guoyin Li
111041-111052
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The association between elevated fasting plasma glucose levels and carotid intima-media thickness in non-diabetic adults: a population-based cross-sectional study

The association between elevated fasting plasma glucose levels and carotid intima-media thickness in non-diabetic adults: a population-based cross-sectional study

https://doi.org/10.18632/oncotarget.22302

Yalin Guan, Changshen Yu, Min Shi, Jingxian Ni, Yanan Wu, Hongfei Gu, Lingling Bai, Jie Liu, Jun Tu, Jinghua Wang,  and Xianjia Ning
111053-111063
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Systemic bioinformatics analysis of recurrent aphthous stomatitis gene expression profiles

Systemic bioinformatics analysis of recurrent aphthous stomatitis gene expression profiles

https://doi.org/10.18632/oncotarget.22347

Jian Wu, Zheng-Ping Chen, An-Quan Shang, Wei-Wei Wang, Zong-Ning Chen, Yun-Juan Tao, Yue Zhou,  and Wan-Xiang Wang
111064-111072
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Diagnostic performance of 68Gallium-PSMA-11 PET/CT to detect significant prostate cancer and comparison with 18FEC PET/CT

Diagnostic performance of 68Gallium-PSMA-11 PET/CT to detect significant prostate cancer and comparison with 18FEC PET/CT

https://doi.org/10.18632/oncotarget.22441

Manuela A. Hoffmann, Matthias Miederer, Helmut J. Wieler, Christian Ruf, Frank M. Jakobs,  and Mathias Schreckenberger
111073-111083
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Integrative molecular network analysis identifies emergent enzalutamide resistance mechanisms in prostate cancer

Integrative molecular network analysis identifies emergent enzalutamide resistance mechanisms in prostate cancer

https://doi.org/10.18632/oncotarget.22560

Carly J. King, Josha Woodward, Jacob Schwartzman, Daniel J. Coleman, Robert Lisac, Nicholas J. Wang, Kathryn Van Hook, Lina Gao, Joshua Urrutia, Mark A. Dane, Laura M. Heiser,  and Joshi J. Alumkal
111084-111095
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Identifying the dynamics of actin and tubulin polymerization in iPSCs and in iPSC-derived neurons

Identifying the dynamics of actin and tubulin polymerization in iPSCs and in iPSC-derived neurons

https://doi.org/10.18632/oncotarget.22571

Valentina Magliocca, Stefania Petrini, Tiziana Franchin, Rossella Borghi, Alessia Niceforo, Zeinab Abbaszadeh, Enrico Bertini,  and Claudia Compagnucci
111096-111109
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Discovery of a highly selective KIT kinase primary V559D mutant inhibitor for gastrointestinal stromal tumors (GISTs)

Discovery of a highly selective KIT kinase primary V559D mutant inhibitor for gastrointestinal stromal tumors (GISTs)

https://doi.org/10.18632/oncotarget.22624

Kailin Yu, Xuesong Liu, Zongru Jiang, Chen Hu, Fengming Zou, Cheng Chen, Juan Ge, Jiaxin Wu, Xiaochuan Liu, Aoli Wang, Wenliang Wang, Wenchao Wang, Ziping Qi, Beilei Wang, Li Wang, Hezhong Yan, Jiaoxue Wang, Tao Ren, Jun Tang, Qingsong Liu,  and Jing Liu
111110-111118
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Identification of potential genetic causal variants for rheumatoid arthritis by whole-exome sequencing

Identification of potential genetic causal variants for rheumatoid arthritis by whole-exome sequencing

https://doi.org/10.18632/oncotarget.22630

Ying Li, Elaine Lai-Han Leung, Hudan Pan, Xiaojun Yao, Qingchun Huang, Min Wu, Ting Xu, Yuwei Wang, Jun Cai, Runze Li, Wei Liu,  and Liang Liu
111119-111129
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Clinical significance of YAP1 activation in head and neck squamous cell carcinoma

Clinical significance of YAP1 activation in head and neck squamous cell carcinoma

https://doi.org/10.18632/oncotarget.22666

Young-Gyu Eun, Dongjin Lee, Young Chan Lee, Bo Hwa Sohn, Eui Hyun Kim, Sun Young Yim, Kee Hwan Kwon,  and Ju-Seog Lee
111130-111143
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Cepharanthine hydrochloride reverses the mdr1 (P-glycoprotein)-mediated esophageal squamous cell carcinoma cell cisplatin resistance through JNK and p53 signals

Cepharanthine hydrochloride reverses the mdr1 (P-glycoprotein)-mediated esophageal squamous cell carcinoma cell cisplatin resistance through JNK and p53 signals

https://doi.org/10.18632/oncotarget.22676

Pengjun Zhou, Rong Zhang, Ying Wang, Dandan Xu, Li Zhang, Jinhong Qin, Guifeng Su, Yue Feng, Hongce Chen, Siyuan You, Wen Rui, Huizhong Liu, Suhong Chen, Hongyuan Chen,  and Yifei Wang
111144-111160
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RIP140 and LCoR expression in gastrointestinal cancers

RIP140 and LCoR expression in gastrointestinal cancers

https://doi.org/10.18632/oncotarget.22686

Mouna Triki, Dorra Ben Ayed-Guerfali, Ines Saguem, Slim Charfi, Lobna Ayedi, Tahia Sellami-Boudawara, Vincent Cavailles,  and Raja Mokdad-Gargouri
111161-111175
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Sampling from single-cell observations to predict tumor cell growth in-vitro and in-vivo

Sampling from single-cell observations to predict tumor cell growth in-vitro and in-vivo

https://doi.org/10.18632/oncotarget.22693

Alexander T. Pearson, Patrick Ingram, Shoumei Bai, Patrick O'Hayer, Jaehoon Chung, Euisik Yoon, Trachette Jackson,  and Ronald J. Buckanovich
111176-111189
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Inhibition of polo-like kinase 4 (PLK4): a new therapeutic option for rhabdoid tumors and pediatric medulloblastoma

Inhibition of polo-like kinase 4 (PLK4): a new therapeutic option for rhabdoid tumors and pediatric medulloblastoma

https://doi.org/10.18632/oncotarget.22704

Simone Treiger Sredni, Anders W. Bailey, Amreena Suri, Rintaro Hashizume, Xingyao He, Nundia Louis, Tufan Gokirmak, David R. Piper, Daniel M. Watterson,  and Tadanori Tomita
111190-111212
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Alteration of mitochondrial biogenesis promotes disease progression in multiple myeloma

Alteration of mitochondrial biogenesis promotes disease progression in multiple myeloma

https://doi.org/10.18632/oncotarget.22740

Xin Zhan, Wenjie Yu, Reinaldo Franqui-Machin, Melissa L. Bates, Kalyan Nadiminti, Huojun Cao, Brad A. Amendt, Yogesh Jethava, Ivana Frech, Fenghuang Zhan,  and Guido Tricot
111213-111224
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Pharmacological treatment with inhibitors of nuclear export enhances the antitumor activity of docetaxel in human prostate cancer

Pharmacological treatment with inhibitors of nuclear export enhances the antitumor activity of docetaxel in human prostate cancer

https://doi.org/10.18632/oncotarget.22760

Giovanni Luca Gravina, Andrea Mancini, Alessandro Colapietro, Francesco Marampon, Roberta Sferra, Simona Pompili, Leda Assunta Biordi, Roberto Iorio, Vincenzo Flati, Christian Argueta, Yosef Landesman, Michael Kauffman, Sharon Shacham,  and Claudio Festuccia
111225-111245
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Molecular characteristics and clinical outcomes of EGFR exon 19 indel subtypes to EGFR TKIs in NSCLC patients

Molecular characteristics and clinical outcomes of EGFR exon 19 indel subtypes to EGFR TKIs in NSCLC patients

https://doi.org/10.18632/oncotarget.22768

Jian Su, Wenzhao Zhong, Xuchao Zhang, Ying Huang, Honghong Yan, Jinji Yang, Zhongyi Dong, Zhi Xie, Qing Zhou, Xiaosui Huang, Danxia Lu, Wenqing Yan,  and Yi-Long Wu
111246-111257
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MicroRNA-34a inhibits cells proliferation and invasion by downregulating Notch1 in endometrial cancer

MicroRNA-34a inhibits cells proliferation and invasion by downregulating Notch1 in endometrial cancer

https://doi.org/10.18632/oncotarget.22770

Zhen Wang, Wei Wang, Kangrong Huang, Yueling Wang, Jing Li,  and Xinyuan Yang
111258-111270
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Gene expression profiling and construction of a putative gene regulatory network of bladder cancer tumor-initiating cells

Gene expression profiling and construction of a putative gene regulatory network of bladder cancer tumor-initiating cells

https://doi.org/10.18632/oncotarget.22771

Zhuoyuan Xin, Zhao Yang, Jianting Xu, Chaoying Li, Tong Shao, Guoqing Wang,  and Chong Li
111271-111280
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Indomethacin-based stimuli-responsive micelles combined with paclitaxel to overcome multidrug resistance

Indomethacin-based stimuli-responsive micelles combined with paclitaxel to overcome multidrug resistance

https://doi.org/10.18632/oncotarget.22781

Shuanghu Wang, Xueying Tan, Shujuan Li, Yunfang Zhou, Peiwu Geng, Ailian Hua, Aiping Deng,  and Zhihong Yu
111281-111294
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Febuxostat attenuates ER stress mediated kidney injury in a rat model of hyperuricemic nephropathy

Febuxostat attenuates ER stress mediated kidney injury in a rat model of hyperuricemic nephropathy

https://doi.org/10.18632/oncotarget.22784

Li He, Ying Fan, Wenzhen Xiao, Teng Chen, Jiejun Wen, Yang Dong, Yiyun Wang, Shiqi Li, Rui Xue, Liyang Zheng, John Cijiang He,  and Niansong Wang
111295-111308
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Concurrent brain radiotherapy and EGFR-TKI may improve intracranial metastases control in non-small cell lung cancer and have survival benefit in patients with low DS-GPA score

Concurrent brain radiotherapy and EGFR-TKI may improve intracranial metastases control in non-small cell lung cancer and have survival benefit in patients with low DS-GPA score

https://doi.org/10.18632/oncotarget.22785

Yongmei Liu, Lei Deng, Xiaojuan Zhou, Youling Gong, Yong Xu, Lin Zhou, Jin Wan, Bingwen Zou, Yongsheng Wang, Jiang Zhu, Zhenyu Ding, Feng Peng, Meijuan Huang, Li Ren, Tim Lautenschlaeger, Feng-Ming (Spring) Kong,  and You Lu
111309-111317
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Temozolomide encapsulated and folic acid decorated chitosan nanoparticles for lung tumor targeting: improving therapeutic efficacy both in vitro and in vivo

Temozolomide encapsulated and folic acid decorated chitosan nanoparticles for lung tumor targeting: improving therapeutic efficacy both in vitro and in vivo

https://doi.org/10.18632/oncotarget.22791

Kaidi Li, Naixin Liang, Huaxia Yang, Hongsheng Liu,  and Shanqing Li
111318-111332
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Aberrant expression of STYK1 and E-cadherin confer a poor prognosis for pancreatic cancer patients

Aberrant expression of STYK1 and E-cadherin confer a poor prognosis for pancreatic cancer patients

https://doi.org/10.18632/oncotarget.22794

Luguang Chen, Chao Ma, Yun Bian, Chengwei Shao, Tiegong Wang, Jing Li, Xiaodan Chong, Li Su,  and Jianping Lu
111333-111345
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A multicenter prospective phase II study of first-line modified FOLFIRINOX for unresectable advanced pancreatic cancer

A multicenter prospective phase II study of first-line modified FOLFIRINOX for unresectable advanced pancreatic cancer

https://doi.org/10.18632/oncotarget.22795

Kensaku Yoshida, Takuji Iwashita, Shinya Uemura, Akinori Maruta, Mitsuru Okuno, Nobuhiro Ando, Keisuke Iwata, Jyunji Kawaguchi, Tsuyoshi Mukai,  and Masahito Shimizu
111346-111355
Abstract  |  PDF  |  HTML  |  Order a Reprint

MicroRNA-95 promotes myogenic differentiation by down-regulation of aminoacyl-tRNA synthase complex-interacting multifunctional protein 2

MicroRNA-95 promotes myogenic differentiation by down-regulation of aminoacyl-tRNA synthase complex-interacting multifunctional protein 2

https://doi.org/10.18632/oncotarget.22796

Biao Li, Shanshan Xie, Chunbo Cai, Lili Qian, Shengwang Jiang, Dezun Ma, Gaojun Xiao, Ting Gao, Jinzeng Yang,  and Wentao Cui
111356-111368
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Assessment of antimicrobial and wound healing effects of Brevinin-2Ta against the bacterium Klebsiella pneumoniae in dermally-wounded rats

Assessment of antimicrobial and wound healing effects of Brevinin-2Ta against the bacterium Klebsiella pneumoniae in dermally-wounded rats

https://doi.org/10.18632/oncotarget.22797

Siqin Liu, Qilin Long, Yang Xu, Jun Wang, Zhongwei Xu, Lei Wang, Mei Zhou, Yuxin Wu, Tianbao Chen,  and Chris Shaw
111369-111385
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Analysis of the mutational landscape of classic Hodgkin lymphoma identifies disease heterogeneity and potential therapeutic targets

Analysis of the mutational landscape of classic Hodgkin lymphoma identifies disease heterogeneity and potential therapeutic targets

https://doi.org/10.18632/oncotarget.22799

Elena Mata, Antonio Díaz-López, Ana M. Martín-Moreno, Margarita Sánchez-Beato, Ignacio Varela, María J. Mestre, Carlos Santonja, Fernando Burgos, Javier Menárguez, Mónica Estévez, Mariano Provencio, Beatriz Sánchez-Espiridión, Eva Díaz, Carlos Montalbán, Miguel A. Piris,  and Juan F. García
111386-111395
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Correlation of psychooncological distress- screening and quality of life assessment in neurosurgical patients

Correlation of psychooncological distress- screening and quality of life assessment in neurosurgical patients

https://doi.org/10.18632/oncotarget.22802

Kira Hoffmann, Marcel Kamp, Hans-Jakob Steiger, Michael Sabel,  and Marion Rapp
111396-111404
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A molecular signature of dormancy in CD34+CD38- acute myeloid leukaemia cells

A molecular signature of dormancy in CD34+CD38- acute myeloid leukaemia cells

https://doi.org/10.18632/oncotarget.22808

. Al-Asadi, Grace Brindle, Marcos Castellanos, Sean T. May, Ken I. Mills, Nigel H. Russell, Claire H. Seedhouse,  and Monica Pallis
111405-111418
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Antitumor activity of resveratrol against human osteosarcoma cells: a key role of Cx43 and Wnt/β-catenin signaling pathway

Antitumor activity of resveratrol against human osteosarcoma cells: a key role of Cx43 and Wnt/β-catenin signaling pathway

https://doi.org/10.18632/oncotarget.22810

Da Xie, Gui-Zhou Zheng, Peng Xie, Qi-Hao Zhang, Fei-Xiang Lin, Bo Chang, Qin-Xiao Hu, Shi-Xin Du,  and Xue-Dong Li
111419-111432
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Integrating gene and lncRNA expression to infer subpathway activity for tumor analyses

Integrating gene and lncRNA expression to infer subpathway activity for tumor analyses

https://doi.org/10.18632/oncotarget.22811

Chunlong Zhang, Yanjun Xu, Haixiu Yang, Yingqi Xu, Qun Dong, Siyao Liu, Tan Wu,  and Yunpeng Zhang
111433-111443
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Clinicopathological and prognostic significance of SDC1 overexpression in breast cancer

Clinicopathological and prognostic significance of SDC1 overexpression in breast cancer

https://doi.org/10.18632/oncotarget.22820

Xiangrong Cui, Xuan Jing, Qin Yi, Chunlan Long, Jie Tian,  and Jing Zhu
111444-111455
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The effects of tumor necrosis factor-α (TNF-α) rs1800629 and rs361525 polymorphisms on sepsis risk

The effects of tumor necrosis factor-α (TNF-α) rs1800629 and rs361525 polymorphisms on sepsis risk

https://doi.org/10.18632/oncotarget.22824

Yixin Zhang, Xiaoteng Cui, Li Ning,  and Dianjun Wei
111456-111469
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Chaperonin containing TCP-1 subunit 3 is critical for gastric cancer growth

Chaperonin containing TCP-1 subunit 3 is critical for gastric cancer growth

https://doi.org/10.18632/oncotarget.22838

Li-Juan Li, Lian-Sheng Zhang, Zhi-Jian Han, Zhi-Yun He, Hao Chen,  and Yu-Min Li
111470-111481
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Methylenetetrahydrofolate reductase tagging polymorphisms are associated with risk of esophagogastric junction adenocarcinoma: a case-control study involving 2,740 Chinese Han subjects

Methylenetetrahydrofolate reductase tagging polymorphisms are associated with risk of esophagogastric junction adenocarcinoma: a case-control study involving 2,740 Chinese Han subjects

https://doi.org/10.18632/oncotarget.22845

Guowen Ding, Yafeng Wang, Yu Chen, Jun Yin, Chao Liu, Yu Fan, Hao Qiu, Weifeng Tang,  and Shuchen Chen
111482-111494
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A novel orally available Syk/Src/Jak2 inhibitor, SKLB-850, showed potent anti-tumor activities in B cell lymphoma (BCL) models

A novel orally available Syk/Src/Jak2 inhibitor, SKLB-850, showed potent anti-tumor activities in B cell lymphoma (BCL) models

https://doi.org/10.18632/oncotarget.22847

Nannan Zhang, Guo Zhang, Ning Liu, Wanting Lin, Sen Ji, Mingwu Zheng, Kai Chen, Xiao Liang, Guobo Li, Yu Ma, Jun Zhu, Ting Niu, Lin-Li Li, Jiong Li, Yu-Quan Wei,  and Sheng-Yong Yang
111495-111507
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Hypoxia-inducible factor-1α regulates microglial functions affecting neuronal survival in the acute phase of ischemic stroke in mice

Hypoxia-inducible factor-1α regulates microglial functions affecting neuronal survival in the acute phase of ischemic stroke in mice

https://doi.org/10.18632/oncotarget.22851

Seoyeon Bok, Young-Eun Kim, Youngsik Woo, Soeun Kim, Suk-Jo Kang, Yoontae Lee, Sang Ki Park, Irving L. Weissman,  and G-One Ahn
111508-111521
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Hyperbaric oxygen protects against myocardial reperfusion injury via the inhibition of inflammation and the modulation of autophagy

Hyperbaric oxygen protects against myocardial reperfusion injury via the inhibition of inflammation and the modulation of autophagy

https://doi.org/10.18632/oncotarget.22869

Chunxia Chen, Wan Chen, Yaoxuan Li, Yanling Dong, Xiaoming Teng, Zhihuan Nong, Xiaorong Pan, Liwen Lv, Ying Gao,  and Guangwei Wu
111522-111534
Abstract  |  PDF  |  HTML  |  Order a Reprint

YM155 exerts potent cytotoxic activity against quiescent (G0/G1) multiple myeloma and bortezomib resistant cells via inhibition of survivin and Mcl-1

YM155 exerts potent cytotoxic activity against quiescent (G0/G1) multiple myeloma and bortezomib resistant cells via inhibition of survivin and Mcl-1

https://doi.org/10.18632/oncotarget.22871

Miyuki Ookura, Tatsuya Fujii, Hideki Yagi, Takuya Ogawa, Shinji Kishi, Naoko Hosono, Hiroko Shigemi, Takahiro Yamauchi, Takanori Ueda,  and Akira Yoshida
111535-111550
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Identification of novel diagnostic biomarkers for thyroid carcinoma

Identification of novel diagnostic biomarkers for thyroid carcinoma

https://doi.org/10.18632/oncotarget.22873

Xiliang Wang, Qing Zhang, Zhiming Cai, Yifan Dai,  and Lisha Mou
111551-111566
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Extracting microtentacle dynamics of tumor cells in a non-adherent environment

Extracting microtentacle dynamics of tumor cells in a non-adherent environment

https://doi.org/10.18632/oncotarget.22874

Eleanor C. Ory, Desu Chen, Kristi R. Chakrabarti, Peipei Zhang, James I. Andorko, Christopher M. Jewell, Wolfgang Losert,  and Stuart S. Martin
111567-111580
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Mitochondrial ROS activates ERK/autophagy pathway as a protected mechanism against deoxypodophyllotoxin-induced apoptosis

Mitochondrial ROS activates ERK/autophagy pathway as a protected mechanism against deoxypodophyllotoxin-induced apoptosis

https://doi.org/10.18632/oncotarget.22875

Sang-Hun Kim, Kwang-Youn Kim, Sul-Gi Park, Sun-Nyoung Yu, Young-Wook Kim, Hyo-Won Nam, Hyun-Hee An, Young-Woo Kim,  and Soon-Cheol Ahn
111581-111596
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NLRP6 targeting suppresses gastric tumorigenesis via P14ARF–Mdm2–P53-dependent cellular senescence

NLRP6 targeting suppresses gastric tumorigenesis via P14ARF–Mdm2–P53-dependent cellular senescence

https://doi.org/10.18632/oncotarget.22876

Haibin Wang, Guoxing Xu, Zhengjie Huang, Weizheng Li, Huali Cai, Yunda Zhang, Disheng Xiong, Gang Liu, Shengjie Wang, Zengfu Xue,  and Qi Luo
111597-111607
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Differential gene expression profiles between two subtypes of ischemic stroke with blood stasis syndromes

Differential gene expression profiles between two subtypes of ischemic stroke with blood stasis syndromes

https://doi.org/10.18632/oncotarget.22877

Tian-Long Liu, Min-Na Liu, Xin-Liang Xu, Wen-Xing Liu, Pei-Jin Shang, Xiao-Hu Zhai, Hang Xu, Yi Ding, Yu-Wen Li,  and Ai-Dong Wen
111608-111622
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

High expression of angiogenic factor AGGF1 is an independent prognostic factor for hepatocellular carcinoma

High expression of angiogenic factor AGGF1 is an independent prognostic factor for hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.22880

Jianfei Tu, Xihui Ying, Dengke Zhang, Qiaoyou Weng, Weibo Mao, Li Chen, Xulu Wu, Chaoyong Tu, Jiansong Ji,  and Yuan Huang
111623-111630
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Inhibition of tumor necrosis factor signaling attenuates renal immune cell infiltration in experimental membranous nephropathy

Inhibition of tumor necrosis factor signaling attenuates renal immune cell infiltration in experimental membranous nephropathy

https://doi.org/10.18632/oncotarget.22881

Yen-Sung Huang, Shin-Huei Fu, Kuo-Cheng Lu, Jin-Shuen Chen, Hsin-Yi Hsieh, Huey-Kang Sytwu,  and Chia-Chao Wu
111631-111641
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PCPA protects against monocrotaline-induced pulmonary arterial remodeling in rats: potential roles of connective tissue growth factor

PCPA protects against monocrotaline-induced pulmonary arterial remodeling in rats: potential roles of connective tissue growth factor

https://doi.org/10.18632/oncotarget.22882

Yang Bai, Zhong-Xia Li, Yue-Tong Zhao, Mo Liu, Yun Wang, Guo-Chao Lian, Qi Zhao,  and Huai-Liang Wang
111642-111655
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Reciprocal sensitivity of diffuse large B-cell lymphoma cells to Bcl-2 inhibitors BIRD-2 versus venetoclax

Reciprocal sensitivity of diffuse large B-cell lymphoma cells to Bcl-2 inhibitors BIRD-2 versus venetoclax

https://doi.org/10.18632/oncotarget.22898

Tamara Vervloessem, Haidar Akl, Thomas Tousseyn, Humbert De Smedt, Jan B. Parys,  and Geert Bultynck
111656-111671
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Next-generation sequencing-based microRNA profiling of mice testis subjected to transient heat stress

Next-generation sequencing-based microRNA profiling of mice testis subjected to transient heat stress

https://doi.org/10.18632/oncotarget.22900

Meng Rao, Zhengyan Zeng, Li Tang, Guiping Cheng, Wei Xia,  and Changhong Zhu
111672-111682
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CRISPR-Cas9 HDR system enhances AQP1 gene expression

CRISPR-Cas9 HDR system enhances AQP1 gene expression

https://doi.org/10.18632/oncotarget.22901

Zhimin Wang, Yaohe Wang, Songling Wang, Li-Rong Zhang, Na Zhang, Zhenguo Cheng, Qingshi Liu, Kelly J. Shields, Baoli Hu,  and Michael J. Passineau
111683-111696
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

6-(Methylsulfonyl) hexyl isothiocyanate as potential chemopreventive agent: molecular and cellular profile in leukaemia cell lines

6-(Methylsulfonyl) hexyl isothiocyanate as potential chemopreventive agent: molecular and cellular profile in leukaemia cell lines

https://doi.org/10.18632/oncotarget.22902

Monia Lenzi, Veronica Cocchi, Marco Malaguti, Maria Cristina Barbalace, Silvia Marchionni, Silvana Hrelia,  and Patrizia Hrelia
111697-111714
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Up-regulation of lncRNA SNHG1 indicates poor prognosis and promotes cell proliferation and metastasis of colorectal cancer by activation of the Wnt/β-catenin signaling pathway

Up-regulation of lncRNA SNHG1 indicates poor prognosis and promotes cell proliferation and metastasis of colorectal cancer by activation of the Wnt/β-catenin signaling pathway

https://doi.org/10.18632/oncotarget.22903

Yuping Zhu, Bo Li, Zhuo Liu, Lai Jiang, Gang Wang, Min Lv,  and Dechuan Li
111715-111727
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Identification of antipsychotic drug fluspirilene as a potential anti-glioma stem cell drug

Identification of antipsychotic drug fluspirilene as a potential anti-glioma stem cell drug

https://doi.org/10.18632/oncotarget.22904

Yu Dong, Takuya Furuta, Hemragul Sabit, Tomohiro Kitabayashi, Shabierjiang Jiapaer, Masahiko Kobayashi, Yasushi Ino, Tomoki Todo, Lei Teng, Atsushi Hirao, Shi-Guang Zhao,  and Mitsutoshi Nakada
111728-111741
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Identification of bladder cancer prognostic biomarkers using an ageing gene-related competitive endogenous RNA network

Identification of bladder cancer prognostic biomarkers using an ageing gene-related competitive endogenous RNA network

https://doi.org/10.18632/oncotarget.22905

Changliang Wang, Liang Chen, Yang Yang, Menglei Zhang,  and Garry Wong
111742-111753
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

LncRNA RNCR3 promotes Chop expression by sponging miR-185-5p during MDSC differentiation

LncRNA RNCR3 promotes Chop expression by sponging miR-185-5p during MDSC differentiation

https://doi.org/10.18632/oncotarget.22906

Wencong Shang, Zhenzhen Tang, Yunhuan Gao, Houbao Qi, Xiaomin Su, Yuan Zhang,  and Rongcun Yang
111754-111769
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

High glucose enhances the metastatic potential of tongue squamous cell carcinoma via the PKM2 pathway

High glucose enhances the metastatic potential of tongue squamous cell carcinoma via the PKM2 pathway

https://doi.org/10.18632/oncotarget.22907

Wei Wang, Qianting He, Wangxiang Yan, Jingjing Sun, Zujian Chen, Zhonghua Liu, Zhiyuan Lu, Jinsong Hou, Yisen Shao, Xiaofeng Zhou,  and Anxun Wang
111770-111779
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Fatty acid binding protein 4 enhances prostate cancer progression by upregulating matrix metalloproteinases and stromal cell cytokine production

Fatty acid binding protein 4 enhances prostate cancer progression by upregulating matrix metalloproteinases and stromal cell cytokine production

https://doi.org/10.18632/oncotarget.22908

Mingguo Huang, Shintaro Narita, Takamitsu Inoue, Atsushi Koizumi, Mitsuru Saito, Hiroshi Tsuruta, Kazuyuki Numakura, Shigeru Satoh, Hiroshi Nanjo, Takehiko Sasaki,  and Tomonori Habuchi
111780-111794
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

First-line dose-dense chemotherapy with docetaxel, cisplatin, folinic acid and 5-fluorouracil (DCF) plus panitumumab in patients with locally advanced or metastatic cancer of the stomach or gastroesophageal junction: final results and biomarker analysis from an Italian oncology group for clinical research (GOIRC) phase II study

First-line dose-dense chemotherapy with docetaxel, cisplatin, folinic acid and 5-fluorouracil (DCF) plus panitumumab in patients with locally advanced or metastatic cancer of the stomach or gastroesophageal junction: final results and biomarker analysis from an Italian oncology group for clinical research (GOIRC) phase II study

https://doi.org/10.18632/oncotarget.22909

Gianluca Tomasello, Nicola Valeri, Michele Ghidini, Elizabeth C. Smyth, Wanda Liguigli, Laura Toppo, Rodolfo Mattioli, Alessandra Curti, Jens C. Hahne, Federica M. Negri, Stefano Panni, Margherita Ratti, Silvia Lazzarelli, Fabiana Gerevini, Chiara Colombi, Andrea Panni, Massimo Rovatti, Leonardo Treccani, Mario Martinotti,  and Rodolfo Passalacqua
111795-111806
Abstract  |  PDF  |  HTML  |  Order a Reprint

Leucine mediates autophagosome-lysosome fusion and improves sperm motility by activating the PI3K/Akt pathway

Leucine mediates autophagosome-lysosome fusion and improves sperm motility by activating the PI3K/Akt pathway

https://doi.org/10.18632/oncotarget.22910

Jin Zhang, Xuemei Zhang, Yingjie Liu, Zihao Su, Farman Ullah Dawar, Hong Dan, Yan He, Jian-Fang Gui,  and Jie Mei
111807-111818
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Can urologists introduce the concept of “oligometastasis” for metastatic bladder cancer after total cystectomy?

Can urologists introduce the concept of “oligometastasis” for metastatic bladder cancer after total cystectomy?

https://doi.org/10.18632/oncotarget.22911

Koichiro Ogihara, Eiji Kikuchi, Keitaro Watanabe, Ryohei Kufukihara, Yoshinori Yanai, Kimiharu Takamatsu, Kazuhiro Matsumoto, Satoshi Hara, Masafumi Oyama, Tetsuo Monma, Takeshi Masuda, Shintaro Hasegawa,  and Mototsugu Oya
111819-111835
Abstract  |  PDF  |  HTML  |  Order a Reprint

Tumoral immune-infiltrate (IF), PD-L1 expression and role of CD8/TIA-1 lymphocytes in localized osteosarcoma patients treated within protocol ISG-OS1

Tumoral immune-infiltrate (IF), PD-L1 expression and role of CD8/TIA-1 lymphocytes in localized osteosarcoma patients treated within protocol ISG-OS1

https://doi.org/10.18632/oncotarget.22912

Emanuela Palmerini, Claudio Agostinelli, Piero Picci, Stefano Pileri, Teresa Marafioti, Pier-Luigi Lollini, Katia Scotlandi, Alessandra Longhi, Maria Serena Benassi,  and Stefano Ferrari
111836-111846
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

CRISPR/Cas9-mediated reversibly immortalized mouse bone marrow stromal stem cells (BMSCs) retain multipotent features of mesenchymal stem cells (MSCs)

CRISPR/Cas9-mediated reversibly immortalized mouse bone marrow stromal stem cells (BMSCs) retain multipotent features of mesenchymal stem cells (MSCs)

https://doi.org/10.18632/oncotarget.22915

Xue Hu, Li Li, Xinyi Yu, Ruyi Zhang, Shujuan Yan, Zongyue Zeng, Yi Shu, Chen Zhao, Xingye Wu, Jiayan Lei, Yasha Li, Wenwen Zhang, Chao Yang, Ke Wu, Ying Wu, Liping An, Shifeng Huang, Xiaojuan Ji, Cheng Gong, Chengfu Yuan, Linghuan Zhang, Wei Liu, Bo Huang, Yixiao Feng, Bo Zhang, Rex C. Haydon, Hue H. Luu, Russell R. Reid, Michael J. Lee, Jennifer Moriatis Wolf, Zebo Yu,  and Tong-Chuan He
111847-111865
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

S-adenosyl-methionine (SAM) alters the transcriptome and methylome and specifically blocks growth and invasiveness of liver cancer cells

S-adenosyl-methionine (SAM) alters the transcriptome and methylome and specifically blocks growth and invasiveness of liver cancer cells

https://doi.org/10.18632/oncotarget.22942

Yan Wang, ZhongSheng Sun,  and Moshe Szyf
111866-111881
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

ICAM-1 regulates macrophage polarization by suppressing MCP-1 expression via miR-124 upregulation

ICAM-1 regulates macrophage polarization by suppressing MCP-1 expression via miR-124 upregulation

https://doi.org/10.18632/oncotarget.22948

Wei Gu, Lun Yao, Lexing Li, Jianping Zhang, Aaron T. Place, Richard D. Minshall,  and Guoquan Liu
111882-111901
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A plasma miRNA signature for lung cancer early detection

A plasma miRNA signature for lung cancer early detection

https://doi.org/10.18632/oncotarget.22950

Qixin Leng, Yanli Lin, Fangran Jiang, Cheng-Ju Lee, Min Zhan, HongBin Fang, Yue Wang,  and Feng Jiang
111902-111911
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The inhibition of cordycepin on cancer stemness in TGF-beta induced chemo-resistant ovarian cancer cell

The inhibition of cordycepin on cancer stemness in TGF-beta induced chemo-resistant ovarian cancer cell

https://doi.org/10.18632/oncotarget.22951

Chia-Woei Wang, Bao-Hong Lee,  and Chen-Jei Tai
111912-111921
Abstract  |  PDF  |  HTML  |  Order a Reprint

IGF-1 induces the epithelial-mesenchymal transition via Stat5 in hepatocellular carcinoma

IGF-1 induces the epithelial-mesenchymal transition via Stat5 in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.22952

Chuanzong Zhao, Qian Wang, Ben Wang, Qi Sun, Zhaobin He, Jianguo Hong, Florian Kuehn, Enyu Liu,  and Zongli Zhang
111922-111930
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The impact of antibiotic usage on the efficacy of chemoimmunotherapy is contingent on the source of tumor-reactive T cells

The impact of antibiotic usage on the efficacy of chemoimmunotherapy is contingent on the source of tumor-reactive T cells

https://doi.org/10.18632/oncotarget.22953

Michal P. Kuczma, Zhi-Chun Ding, Tao Li, Tsadik Habtetsion, Tingting Chen, Zhonglin Hao, Locke Bryan, Nagendra Singh, James N. Kochenderfer,  and Gang Zhou
111931-111942
Abstract  |  PDF  |  HTML  |  Order a Reprint

Anti-neoplastic drugs increase caveolin-1-dependent migration, invasion and metastasis of cancer cells

Anti-neoplastic drugs increase caveolin-1-dependent migration, invasion and metastasis of cancer cells

https://doi.org/10.18632/oncotarget.22955

Natalia I. Díaz-Valdivia, Claudia C. Calderón, Jorge E. Díaz, Lorena Lobos-González, Hugo Sepulveda, Rina J. Ortíz, Samuel Martinez, Veronica Silva, Horacio J. Maldonado, Patricio Silva, Sergio Wehinger, Verónica A. Burzio, Vicente A. Torres, Martín Montecino, Lisette Leyton,  and Andrew F.G. Quest
111943-111965
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Somatic mutation dynamics in MDS patients treated with azacitidine indicate clonal selection in patients-responders

Somatic mutation dynamics in MDS patients treated with azacitidine indicate clonal selection in patients-responders

https://doi.org/10.18632/oncotarget.22957

Kamila Polgarova, Karina Vargova, Vojtech Kulvait, Nina Dusilkova, Lubomir Minarik, Zuzana Zemanova, Michal Pesta, Anna Jonasova,  and Tomas Stopka
111966-111978
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Long-term effects of sitagliptin in patients with type 2 diabetes mellitus and hypertension: results from the PROLOGUE study

Long-term effects of sitagliptin in patients with type 2 diabetes mellitus and hypertension: results from the PROLOGUE study

https://doi.org/10.18632/oncotarget.22959

Ziliang Ye, Hui Li, Haili Lu, Qiang Su,  and Lang Li
111979-111997
Abstract  |  PDF  |  HTML  |  Order a Reprint

A maternal high-fat diet during pregnancy and lactation, in addition to a postnatal high-fat diet, leads to metabolic syndrome with spatial learning and memory deficits: beneficial effects of resveratrol

A maternal high-fat diet during pregnancy and lactation, in addition to a postnatal high-fat diet, leads to metabolic syndrome with spatial learning and memory deficits: beneficial effects of resveratrol

https://doi.org/10.18632/oncotarget.22960

Shih-Wen Li, Hong-Ren Yu, Jiunn-Ming Sheen, Mao-Meng Tiao, You-Lin Tain, I-Chun Lin, Yu-Ju Lin, Kow-Aung Chang, Ching-Chou Tsai,  and Li-Tung Huang
111998-112013
Abstract  |  PDF  |  HTML  |  Order a Reprint

A comparison of ARMS-Plus and droplet digital PCR for detecting EGFR activating mutations in plasma

A comparison of ARMS-Plus and droplet digital PCR for detecting EGFR activating mutations in plasma

https://doi.org/10.18632/oncotarget.22997

Xinxin Zhang, Ning Chang, Guohua Yang, Yong Zhang, Mingxiang Ye, Jing Cao, Jie Xiong, Zhiping Han, Shuo Wu, Lei Shang,  and Jian Zhang
112014-112023
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Effect of gene-lifestyle interaction on gestational diabetes risk

Effect of gene-lifestyle interaction on gestational diabetes risk

https://doi.org/10.18632/oncotarget.22999

Polina V. Popova, Alexandra A. Klyushina, Lyudmila B. Vasilyeva, Alexandra S. Tkachuk, Yana A. Bolotko, Andrey S. Gerasimov, Evgenii A. Pustozerov, Ekaterina N. Kravchuk, Alexander Predeus, Anna A. Kostareva,  and Elena N. Grineva
112024-112035
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Development of a targeted sequencing approach to identify prognostic, predictive and diagnostic markers in paediatric solid tumours

Development of a targeted sequencing approach to identify prognostic, predictive and diagnostic markers in paediatric solid tumours

https://doi.org/10.18632/oncotarget.23000

Elisa Izquierdo, Lina Yuan, Sally George, Michael Hubank, Chris Jones, Paula Proszek, Janet Shipley, Susanne A. Gatz, Caedyn Stinson, Andrew S. Moore, Steven C. Clifford, Debbie Hicks, Janet C. Lindsey, Rebecca M. Hill, Thomas S. Jacques, Jane Chalker, Khin Thway, Simon O’Connor, Lynley Marshall, Lucas Moreno, Andrew Pearson, Louis Chesler, Brian A. Walker,  and David Gonzalez De Castro
112036-112050
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Curcumin attenuates myocardial ischemia–reperfusion injury

Curcumin attenuates myocardial ischemia–reperfusion injury

https://doi.org/10.18632/oncotarget.23002

Kun Liu, Honglin Chen, Qing-Sheng You, Qing Ye, Fei Wang, Shuo Wang, Shuang-Long Zhang, Kang-Jun Yu,  and Qi Lu
112051-112059
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Effect of dihydropyrimidine dehydrogenase single nucleotide polymorphisms on prognosis of breast cancer patients with chemotherapy

Effect of dihydropyrimidine dehydrogenase single nucleotide polymorphisms on prognosis of breast cancer patients with chemotherapy

https://doi.org/10.18632/oncotarget.23033

Fengxia Qin, Huikun Zhang, Yong Huang, Limin Yang, Feng Yu, Xiaoli Liu, Li Fu, Feng Gu,  and Yongjie Ma
112060-112075
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Meta-Analysis

Incidence and relative risk of peripheral neuropathy in cancer patients treated with eribulin: a meta-analysis

Incidence and relative risk of peripheral neuropathy in cancer patients treated with eribulin: a meta-analysis

https://doi.org/10.18632/oncotarget.21057

Ling Peng, Yun Hong, Xianghua Ye, Peng Shi, Junyan Zhang, Yina Wang,  and Qiong Zhao
112076-112084
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Prognostic role of platelet to lymphocyte ratio in esophageal cancer: A meta-analysis

Prognostic role of platelet to lymphocyte ratio in esophageal cancer: A meta-analysis

https://doi.org/10.18632/oncotarget.22557

Qing-Tao Zhao, Xiao-Peng Zhang, Hua Zhang,  and Guo-Chen Duan
112085-112093
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Clinical Research Papers

Survival benefit evaluation of radiotherapy in esophageal cancer patients aged 80 and older

Survival benefit evaluation of radiotherapy in esophageal cancer patients aged 80 and older

https://doi.org/10.18632/oncotarget.22884

Shan Huang, Shuyu Zheng, Tuotuo Gong, Hongbing Ma, Yue Ke, Songchuan Zhao, Wenyu Wang, Lijun Jia,  and Xiaozhi Zhang
112094-112102
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Reviews

Hypermutation and microsatellite instability in gastrointestinal cancers

Hypermutation and microsatellite instability in gastrointestinal cancers

https://doi.org/10.18632/oncotarget.22783

Kizuki Yuza, Masayuki Nagahashi, Satoshi Watanabe, Kazuaki Takabe,  and Toshifumi Wakai
112103-112115
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T follicular helper cells: a potential therapeutic target in follicular lymphoma

T follicular helper cells: a potential therapeutic target in follicular lymphoma

https://doi.org/10.18632/oncotarget.22788

Jordi Ochando,  and Mounia S. Braza
112116-112131
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The regulation of pre-metastatic niche formation by neutrophils

The regulation of pre-metastatic niche formation by neutrophils

https://doi.org/10.18632/oncotarget.22792

Jadwiga Jablonska, Stephan Lang, Ronit Vogt Sionov,  and Zvi Granot
112132-112144
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Apelin/APJ system: A key therapeutic target for liver disease

Apelin/APJ system: A key therapeutic target for liver disease

https://doi.org/10.18632/oncotarget.22841

Shuang-Yu Lv, Binbin Cui, Wei-Dong Chen,  and Yan-Dong Wang
112145-112151
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MEF2 signaling and human diseases

MEF2 signaling and human diseases

https://doi.org/10.18632/oncotarget.22899

Xiao Chen, Bing Gao, Murugavel Ponnusamy, Zhijuan Lin,  and Jia Liu
112152-112165
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