Oncotarget

Vol 8, No 66

December 15, 2017

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About The Cover

The cover for issue 66 of Oncotarget features Figure 7A, "Verteporfin restores PLX4032 suppression of ERK1/2 signaling and tumor formation," from Fisher, et al.

Table of Contents

Editorial

Terminating B cell receptor signaling

Terminating B cell receptor signaling

https://doi.org/10.18632/oncotarget.22986

Dara K. Mohammad, Beston F. Nore,  and CI. Edvard Smith
109857-109858
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Optimizing therapy for del(17p) multiple myeloma

Optimizing therapy for del(17p) multiple myeloma

https://doi.org/10.18632/oncotarget.22987

Hervé Avet-Loiseau, Paul G. Richardson,  and Alessandra di Bacco
109859-109860
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Research Papers

Stromal cell extracellular vesicular cargo mediated regulation of breast cancer cell metastasis via ubiquitin conjugating enzyme E2 N pathway

Stromal cell extracellular vesicular cargo mediated regulation of breast cancer cell metastasis via ubiquitin conjugating enzyme E2 N pathway

https://doi.org/10.18632/oncotarget.22371

Krishna C. Vallabhaneni, Patrice Penfornis, Fei Xing, Yoni Hassler, Kristen V. Adams, Yin-Yuan Mo, Kounosuke Watabe,  and Radhika Pochampally
109861-109876
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Extracellular miR-224 as a prognostic marker for clear cell renal cell carcinoma

Extracellular miR-224 as a prognostic marker for clear cell renal cell carcinoma

https://doi.org/10.18632/oncotarget.22436

Nakanori Fujii, Hiroshi Hirata, Koji Ueno, Junichi Mori, Shintaro Oka, Kosuke Shimizu, Yoshihisa Kawai, Ryo Inoue, Yoshiaki Yamamoto, Hiroaki Matsumoto, Tomoyuki Shimabukuro, Koichi Udoh, Yoshinobu Hoshii, Rajvir Dahiya,  and Hideyasu Matsuyama
109877-109888
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Clinical efficacy of short-course chemotherapy combined with topical injection therapy in treatment of superficial lymph node tuberculosis

Clinical efficacy of short-course chemotherapy combined with topical injection therapy in treatment of superficial lymph node tuberculosis

https://doi.org/10.18632/oncotarget.22492

Huiru An, Zhongyuan Wang, Hongbing Chen, Tao Wang, Xinjing Wang, Lin Liu, Xiao Liu, Jing Xu, Luxing He, Kai Zhang, Hongyan Zhang,  and Xinying Liu
109889-109893
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A new bioluminescent reporter system to study the biodistribution of systematically injected tumor-derived bioluminescent extracellular vesicles in mice

A new bioluminescent reporter system to study the biodistribution of systematically injected tumor-derived bioluminescent extracellular vesicles in mice

https://doi.org/10.18632/oncotarget.22493

Prakash Gangadaran, Xiu Juan Li, Ho Won Lee, Ji Min Oh, Senthilkumar Kalimuthu, Ramya Lakshmi Rajendran, Seung Hyun Son, Se Hwan Baek, Thoudam Debraj Singh, Liya Zhu, Shin Young Jeong, Sang-Woo Lee, Jaetae Lee,  and Byeong-Cheol Ahn
109894-109914
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Identification of a cytogenetic and molecular subgroup of acute myeloid leukemias showing sensitivity to L-Asparaginase

Identification of a cytogenetic and molecular subgroup of acute myeloid leukemias showing sensitivity to L-Asparaginase

https://doi.org/10.18632/oncotarget.18565

Salvatore Nicola Bertuccio, Salvatore Serravalle, Annalisa Astolfi, Annalisa Lonetti, Valentina Indio, Anna Leszl, Andrea Pession,  and Fraia Melchionda
109915-109923
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Identifying mitotane-induced mitochondria-associated membranes dysfunctions: metabolomic and lipidomic approaches

Identifying mitotane-induced mitochondria-associated membranes dysfunctions: metabolomic and lipidomic approaches

https://doi.org/10.18632/oncotarget.18968

Ségolène Hescot, Larbi Amazit, Marie Lhomme, Simon Travers, Anais DuBow, Stephanie Battini, Geoffrey Boulate, Izzie Jacques Namer, Anne Lombes, Anatol Kontush, Alessio Imperiale, Eric Baudin,  and Marc Lombes
109924-109940
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

HIF-1α contributes to hypoxia adaptation of the naked mole rat

HIF-1α contributes to hypoxia adaptation of the naked mole rat

https://doi.org/10.18632/oncotarget.22767

Bang Xiao, Shiyong Wang, Guoshi Yang, Xiaoxi Sun, Shanmin Zhao, Lifang Lin, Jishuai Cheng, Wenjing Yang, Wei Cong, Wei Sun, Guanghan Kan,  and Shufang Cui
109941-109951
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KLF15 promotes the proliferation and metastasis of lung adenocarcinoma cells and has potential as a cancer prognostic marker

KLF15 promotes the proliferation and metastasis of lung adenocarcinoma cells and has potential as a cancer prognostic marker

https://doi.org/10.18632/oncotarget.21972

Lihua Gao, Hongmei Qiu, Jian Liu, Yuzhen Ma, Jia Feng, Li Qian, Jianguo Zhang, Yifei Liu,  and Tingting Bian
109952-109961
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Wnt/β-catenin and Hedgehog pathways are involved in the inflammatory effect of Interleukin 18 on rat chondrocytes

Wnt/β-catenin and Hedgehog pathways are involved in the inflammatory effect of Interleukin 18 on rat chondrocytes

https://doi.org/10.18632/oncotarget.20584

Jiapeng Bao, Chiyuan Ma, Jisheng Ran, Yan Xiong, Shigui Yan,  and Lidong Wu
109962-109972
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Inhibition of SDF-1-induced migration of oncogene-driven myeloid leukemia by the L-RNA aptamer (Spiegelmer), NOX-A12, and potentiation of tyrosine kinase inhibition

Inhibition of SDF-1-induced migration of oncogene-driven myeloid leukemia by the L-RNA aptamer (Spiegelmer), NOX-A12, and potentiation of tyrosine kinase inhibition

https://doi.org/10.18632/oncotarget.22409

Ellen L. Weisberg, Martin Sattler, Abdel Kareem Azab, Dirk Eulberg, Anna Kruschinski, Paul W. Manley, Richard Stone,  and James D. Griffin
109973-109984
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FTY-720 induces apoptosis in neuroblastoma via multiple signaling pathways

FTY-720 induces apoptosis in neuroblastoma via multiple signaling pathways

https://doi.org/10.18632/oncotarget.22452

Ingo Lange, Italo Espinoza-Fuenzalida, Mourad Wagdy Ali, Laura Espana Serrano,  and Dana-Lynn T. Koomoa
109985-109999
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Serum metabolomic profiling of human gastric cancer and its relationship with the prognosis

Serum metabolomic profiling of human gastric cancer and its relationship with the prognosis

https://doi.org/10.18632/oncotarget.21314

Daguang Wang, Wei Li, Qi Zou, Lei Yin, Yechao Du, Jingkai Gu,  and Jian Suo
110000-110015
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HDAC inhibition as a treatment concept to combat temsirolimus-resistant bladder cancer cells

HDAC inhibition as a treatment concept to combat temsirolimus-resistant bladder cancer cells

https://doi.org/10.18632/oncotarget.22454

Eva Juengel, Ramin Najafi, Jochen Rutz, Sebastian Maxeiner, Jasmina Makarevic, Frederik Roos, Igor Tsaur, Axel Haferkamp,  and Roman A. Blaheta
110016-110028
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Adverse stimulation of 4-nonylphenol in abnormal reproductive organs of female chickens

Adverse stimulation of 4-nonylphenol in abnormal reproductive organs of female chickens

https://doi.org/10.18632/oncotarget.21858

Fenghua Zhang, Peng Yang, Lei Qin,  and Jie Zhang
110029-110038
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Estrogen modulates vascular smooth muscle cell function through downregulation of SIRT1

Estrogen modulates vascular smooth muscle cell function through downregulation of SIRT1

https://doi.org/10.18632/oncotarget.22546

Chien-Hsing Lee, Sheng-Chiang Su, Chi-Fu Chiang, Chu-Yen Chien, Chia-Chen Hsu, Tzu-Yi Yu, Shih-Ming Huang, Yi-Shing Shieh, Hong-Wei Kao, Chien-Sung Tsai, Yi-Jen Hung,  and Chih-Yuan Lin
110039-110051
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CDKN2B is critical for verapamil-mediated reversal of doxorubicin resistance in hepatocellular carcinoma

CDKN2B is critical for verapamil-mediated reversal of doxorubicin resistance in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.22123

Tengyue Zhang, Kelong Ma, Jin Huang, Shitang Wang, Yabei Liu, Gaofei Fan, Miao Liu, Guangshan Yang, Cheng Wang,  and Pingsheng Fan
110052-110063
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Lewis y antigen promotes p27 degradation by regulating ubiquitin-proteasome activity

Lewis y antigen promotes p27 degradation by regulating ubiquitin-proteasome activity

https://doi.org/10.18632/oncotarget.22617

Mingbo Cai, Shan Jin, Lu Deng, Liancheng Zhu, Zhenhua Hu, Dawo Liu, Juanjuan Liu, Mingzi Tan, Jian Gao, Huimin Wang,  and Bei Lin
110064-110076
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Strong fascin expression promotes metastasis independent of its F-actin bundling activity

Strong fascin expression promotes metastasis independent of its F-actin bundling activity

https://doi.org/10.18632/oncotarget.22249

Lisa S. Heinz, Stefanie Muhs, Johanna Schiewek, Saskia Grüb, Marcus Nalaskowski, Yuan-Na Lin, Harriet Wikman, Leticia Oliveira-Ferrer, Tobias Lange, Jasmin Wellbrock, Anja Konietzny, Marina Mikhaylova,  and Sabine Windhorst
110077-110091
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Saikosaponins A, C and D enhance liver-targeting effects of anticancer drugs by modulating drug transporters

Saikosaponins A, C and D enhance liver-targeting effects of anticancer drugs by modulating drug transporters

https://doi.org/10.18632/oncotarget.22639

Limin Feng, Lijuan Liu, Ya Zhao,  and Ruizhi Zhao
110092-110102
Abstract  |  PDF  |  HTML  |  Order a Reprint

Domain retention in transcription factor fusion genes and its biological and clinical implications: a pan-cancer study

Domain retention in transcription factor fusion genes and its biological and clinical implications: a pan-cancer study

https://doi.org/10.18632/oncotarget.22653

Pora Kim, Leomar Y. Ballester,  and Zhongming Zhao
110103-110117
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Proteomic changes in cerebrospinal fluid from primary central nervous system lymphoma patients are associated with protein ectodomain shedding

Proteomic changes in cerebrospinal fluid from primary central nervous system lymphoma patients are associated with protein ectodomain shedding

https://doi.org/10.18632/oncotarget.22654

Daniel Michael Waldera-Lupa, Omid Etemad-Parishanzadeh, Mareike Brocksieper, Nina Kirchgaessler, Sabine Seidel, Thomas Kowalski, Manuel Montesinos-Rongen, Martina Deckert, Uwe Schlegel,  and Kai Stühler
110118-110132
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Acquired resistance to PI3K/mTOR inhibition is associated with mitochondrial DNA mutation and glycolysis

Acquired resistance to PI3K/mTOR inhibition is associated with mitochondrial DNA mutation and glycolysis

https://doi.org/10.18632/oncotarget.22655

King Xin Koh, Gim Hwa Tan, Sarah Hong Hui Low, Mohd Feroz Mohd Omar, Min Ji Han, Barry Iacopetta, Ross Soo, Mounia Beloueche-Babari, Bhaskar Bhattacharya,  and Richie Soong
110133-110144
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Genetic variations in TERC and TERT genes are associated with lung cancer risk in a Chinese Han population

Genetic variations in TERC and TERT genes are associated with lung cancer risk in a Chinese Han population

https://doi.org/10.18632/oncotarget.22329

Gang Ye, Nan Tan, Chenyang Meng, Jingjie Li, Li Jing, Mengdan Yan, Tianbo Jin,  and Fulin Chen
110145-110152
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Association of ALDH3B2 gene polymorphism and risk factors with susceptibility of esophageal squamous cell carcinoma in a Chinese population: a case-control study involving 2,358 subjects

Association of ALDH3B2 gene polymorphism and risk factors with susceptibility of esophageal squamous cell carcinoma in a Chinese population: a case-control study involving 2,358 subjects

https://doi.org/10.18632/oncotarget.22656

Jun Yin, Weifeng Tang, Tao Long, Huiwen Pan, Jianchao Liu, Lu Lv, Chao Liu, Yijun Shi, Jingfeng Zhu, Yangyong Sun, Aizhong Shao, Qiang Zhou, Zhengbing Ren, Guowen Ding, Suocheng Chen, Yan Liu, Jun Yao, Hao Ding, Yulan Yan, Haiyong Gu, Cheng Qian, Liming Wang, Qun Wang,  and Lijie Tan
110153-110165
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New role of ID3 in melanoma adaptive drug-resistance

New role of ID3 in melanoma adaptive drug-resistance

https://doi.org/10.18632/oncotarget.22698

Sachindra  , Lionel Larribère, Daniel Novak, Huizi Wu, Laura Hüser, Karol Granados, Elias Orouji,  and Jochen Utikal
110166-110175
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Reduced alternative splicing of estrogen receptor alpha in the endometrium of women with endometriosis

Reduced alternative splicing of estrogen receptor alpha in the endometrium of women with endometriosis

https://doi.org/10.18632/oncotarget.22701

Ying Zhang, Yong Zhang, Chunbo Zhao, Tiantian Yu, Ye Liu, Weihui Shi, Fengtao Shi, Xinmei Liu, Jianzhong Sheng, Hefeng Huang,  and Hong Xu
110176-110186
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MicroRNA-449a maintains self-renewal in liver cancer stem-like cells by targeting Tcf3

MicroRNA-449a maintains self-renewal in liver cancer stem-like cells by targeting Tcf3

https://doi.org/10.18632/oncotarget.22705

Qianzhen Zhang, Zhi Yang, Juanjuan Shan, Limei Liu, Chungang Liu, Junjie Shen, Xuejiao Chen, Yanmin Xu, Jun Chen, Qinghua Ma, Li Yang,  and Cheng Qian
110187-110200
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Optimization of the margin expanded from the clinical to the planned target volume during intensity-modulated radiotherapy for nasopharyngeal carcinoma

Optimization of the margin expanded from the clinical to the planned target volume during intensity-modulated radiotherapy for nasopharyngeal carcinoma

https://doi.org/10.18632/oncotarget.22518

Wang Fangzheng, Sun Quanquan, Jiang Chuner, Ye Zhimin, Yang Shuangyan, Yu Huanhuan, Shi Jianfang, Masoto Sakamoto, Qin Weifeng, Fu Zhenfu, Jiang Yangming,  and Wang Yuezhen
110201-110208
Abstract  |  PDF  |  HTML  |  Order a Reprint

MicroRNA-34a promotes mitochondrial dysfunction-induced apoptosis in human lens epithelial cells by targeting Notch2

MicroRNA-34a promotes mitochondrial dysfunction-induced apoptosis in human lens epithelial cells by targeting Notch2

https://doi.org/10.18632/oncotarget.22597

Fan Fan, Jianhui Zhuang, Peng Zhou, Xin Liu,  and Yi Luo
110209-110220
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Structural determinant of BST-2-mediated regulation of breast cancer cell motility: a role for cytoplasmic tail tyrosine residues

Structural determinant of BST-2-mediated regulation of breast cancer cell motility: a role for cytoplasmic tail tyrosine residues

https://doi.org/10.18632/oncotarget.22753

Wasifa Naushad, Wadie D. Mahauad-Fernandez,  and Chioma M. Okeoma
110221-110233
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

LINCRNA00273 promotes cancer metastasis and its G-Quadruplex promoter can serve as a novel target to inhibit cancer invasiveness

LINCRNA00273 promotes cancer metastasis and its G-Quadruplex promoter can serve as a novel target to inhibit cancer invasiveness

https://doi.org/10.18632/oncotarget.22622

Samarjit Jana, Jagannath Jana, Kartick Patra, Soma Mondal, Jyotsna Bhat, Arnab Sarkar, Pallabi Sengupta, Anindya Biswas, Meghomukta Mukherjee, Satya Prakash Tripathi, Rahul Gangwal, Joyita Hazra, Abhay T. Sangamwar, Gopeswar Mukherjee, Shamee Bhattacharjee, Deba Prasad Mandal,  and Subhrangsu Chatterjee
110234-110256
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Inhibition of YAP function overcomes BRAF inhibitor resistance in melanoma cancer stem cells

Inhibition of YAP function overcomes BRAF inhibitor resistance in melanoma cancer stem cells

https://doi.org/10.18632/oncotarget.22628

Matthew L. Fisher, Daniel Grun, Gautam Adhikary, Wen Xu,  and Richard L. Eckert
110257-110272
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Targeting chaperonin containing TCP1 (CCT) as a molecular therapeutic for small cell lung cancer

Targeting chaperonin containing TCP1 (CCT) as a molecular therapeutic for small cell lung cancer

https://doi.org/10.18632/oncotarget.22681

Ana C. Carr, Amr S. Khaled, Rania Bassiouni, Orielyz Flores, Daniel Nierenberg, Hammad Bhatti, Priya Vishnubhotla, J. Manuel Perez, Santimukul Santra,  and Annette R. Khaled
110273-110288
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Accelerated atherogenesis in completely ligated common carotid artery of apolipoprotein E-deficient mice

Accelerated atherogenesis in completely ligated common carotid artery of apolipoprotein E-deficient mice

https://doi.org/10.18632/oncotarget.22685

Zhihui Chang, Chaoji Huangfu, Andrew T. Grainger, Jingang Zhang, Qiyong Guo,  and Weibin Shi
110289-110299
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Cancer risk susceptibility loci in a Swedish population

Cancer risk susceptibility loci in a Swedish population

https://doi.org/10.18632/oncotarget.22687

Wen Liu, Xiang Jiao, Jessada Thutkawkorapin, Hovsep Mahdessian,  and Annika Lindblom
110300-110310
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The combination of preoperative platelet count and neutrophil lymphocyte ratio as a prognostic indicator in localized renal cell carcinoma

The combination of preoperative platelet count and neutrophil lymphocyte ratio as a prognostic indicator in localized renal cell carcinoma

https://doi.org/10.18632/oncotarget.22688

Takuya Tsujino, Kazumasa Komura, Atsushi Ichihashi, Takeshi Tsutsumi, Tomohisa Matsunaga, Yuki Yoshikawa, Ryoichi Maenosono, Kyohei Okita, Tomoaki Takai, Rintaro Oide, Koichiro Minami, Hirofumi Uehara, Kohei Taniguchi, Hajime Hirano, Hayahito Nomi, Naokazu Ibuki, Kiyoshi Takahara, Teruo Inamoto,  and Haruhito Azuma
110311-110325
Abstract  |  PDF  |  HTML  |  Order a Reprint

Methylenetetrahydrofolate reductase tagging polymorphisms are associated with risk of non-small cell lung cancer in eastern Chinese Han population

Methylenetetrahydrofolate reductase tagging polymorphisms are associated with risk of non-small cell lung cancer in eastern Chinese Han population

https://doi.org/10.18632/oncotarget.22887

Hao Ding, Yafeng Wang, Yuanmei Chen, Chao Liu, Hao Qiu, Mingqiang Kang,  and Weifeng Tang
110326-110336
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Analysis of the codon usage pattern in Middle East Respiratory Syndrome Coronavirus

Analysis of the codon usage pattern in Middle East Respiratory Syndrome Coronavirus

https://doi.org/10.18632/oncotarget.22738

Ye Chen, Quanming Xu, Xiaomin Yuan, Xinxin Li, Ting Zhu, Yanmei Ma,  and Ji-Long Chen
110337-110349
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High-dose sitagliptin for systemic inhibition of dipeptidylpeptidase-4 to enhance engraftment of single cord umbilical cord blood transplantation

High-dose sitagliptin for systemic inhibition of dipeptidylpeptidase-4 to enhance engraftment of single cord umbilical cord blood transplantation

https://doi.org/10.18632/oncotarget.22739

Sherif S. Farag, Robert Nelson, Mitchell S. Cairo, Heather A. O’Leary, Shuhong Zhang, Carol Huntley, David Delgado, Jennifer Schwartz, Mohammad Abu Zaid, Rafat Abonour, Michael Robertson,  and Hal Broxmeyer
110350-110357
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Identify clear cell renal cell carcinoma related genes by gene network

Identify clear cell renal cell carcinoma related genes by gene network

https://doi.org/10.18632/oncotarget.22769

Fangrong Yan, Yue Wang, Chunhui Liu, Huiling Zhao, Liya Zhang, Xiaofan Lu, Chen Chen, Yaoyan Wang, Tao Lu,  and Fei Wang
110358-110366
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Resminostat induces changes in epithelial plasticity of hepatocellular carcinoma cells and sensitizes them to sorafenib-induced apoptosis

Resminostat induces changes in epithelial plasticity of hepatocellular carcinoma cells and sensitizes them to sorafenib-induced apoptosis

https://doi.org/10.18632/oncotarget.22775

Jitka Soukupova, Esther Bertran, Irene Peñuelas-Haro, Uxue Urdiroz-Urricelqui, Matthias Borgman, Hella Kohlhof,  and Isabel Fabregat
110367-110379
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Neuroprotection by aripiprazole against β-amyloid-induced toxicity by P-CK2α activation via inhibition of GSK-3β

Neuroprotection by aripiprazole against β-amyloid-induced toxicity by P-CK2α activation via inhibition of GSK-3β

https://doi.org/10.18632/oncotarget.22777

So Youn Park, Hwa Kyoung Shin, Won Suk Lee, Sun Sik Bae, Koanhoi Kim, Ki Whan Hong,  and Chi Dae Kim
110380-110391
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Inhibition of PI4K IIIα radiosensitizes in human tumor xenograft and immune-competent syngeneic murine tumor model

Inhibition of PI4K IIIα radiosensitizes in human tumor xenograft and immune-competent syngeneic murine tumor model

https://doi.org/10.18632/oncotarget.22778

Younghee Park, Ji Min Park, Dan Hyo Kim, Jeanny Kwon,  and In Ah Kim
110392-110405
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Management of intrahepatic recurrence after resection for hepatocellular carcinoma exceeding the barcelona clinic liver cancer criteria

Management of intrahepatic recurrence after resection for hepatocellular carcinoma exceeding the barcelona clinic liver cancer criteria

https://doi.org/10.18632/oncotarget.22779

Wei Xu, Rui Guo, Gang Xu, Lejia Sun, Dandan Hu, Haifeng Xu, Huayu Yang, Xinting Sang, Xin Lu,  and Yilei Mao
110406-110414
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Smad1 promotes colorectal cancer cell migration through Ajuba transactivation

Smad1 promotes colorectal cancer cell migration through Ajuba transactivation

https://doi.org/10.18632/oncotarget.22780

Daming Yang, Tieying Hou, Lei Li, Yimin Chu, Fengli Zhou, Ying Xu, Xinyu Hou, Huan Song, Kai Zhu, Zhaoyuan Hou, Haixia Peng,  and Hao Jia
110415-110425
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Lactate-activated macrophages induced aerobic glycolysis and epithelial-mesenchymal transition in breast cancer by regulation of CCL5-CCR5 axis: a positive metabolic feedback loop

Lactate-activated macrophages induced aerobic glycolysis and epithelial-mesenchymal transition in breast cancer by regulation of CCL5-CCR5 axis: a positive metabolic feedback loop

https://doi.org/10.18632/oncotarget.22786

Sensen Lin, Li Sun, Xiaodan Lyu, Xiongfei Ai, Danyu Du, Nan Su, Hongyang Li, Luyong Zhang, Jun Yu,  and Shengtao Yuan
110426-110443
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Detection of prognostic methylation markers by methylC-capture sequencing in acute myeloid leukemia

Detection of prognostic methylation markers by methylC-capture sequencing in acute myeloid leukemia

https://doi.org/10.18632/oncotarget.22789

Yan Li, Hongmei Zhao, Qingyu Xu, Na Lv, Yu Jing, Lili Wang, Xiaowen Wang, Jing Guo, Lei Zhou, Jing Liu, Guofeng Chen, Chongjian Chen, Yonghui Li,  and Li Yu
110444-110459
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

N-AC-l-Leu-PEI-mediated miR-34a delivery improves osteogenic differentiation under orthodontic force

N-AC-l-Leu-PEI-mediated miR-34a delivery improves osteogenic differentiation under orthodontic force

https://doi.org/10.18632/oncotarget.22790

Wenwen Yu, Yi Zheng, Zhujun Yang, Hongbo Fei, Yang Wang, Xu Hou, Xinhua Sun,  and Yuqin Shen
110460-110473
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FOXO3 induces ubiquitylation of AKT through MUL1 regulation

FOXO3 induces ubiquitylation of AKT through MUL1 regulation

https://doi.org/10.18632/oncotarget.22793

Sun-Yong Kim, Hyo Jeong Kim, Hyung Kwon Byeon, Dae Ho Kim,  and Chul-Ho Kim
110474-110489
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Ubiquitin Specific Peptidase 15 (USP15) suppresses glioblastoma cell growth via stabilization of HECTD1 E3 ligase attenuating WNT pathway activity

Ubiquitin Specific Peptidase 15 (USP15) suppresses glioblastoma cell growth via stabilization of HECTD1 E3 ligase attenuating WNT pathway activity

https://doi.org/10.18632/oncotarget.22798

Maria Oikonomaki, Pierre Bady,  and Monika E. Hegi
110490-110502
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XPO1 target occupancy measurements confirm the selinexor recommended phase 2 dose

XPO1 target occupancy measurements confirm the selinexor recommended phase 2 dose

https://doi.org/10.18632/oncotarget.22801

Marsha L. Crochiere, Stefan Hannus, Kerrin Hansen, Frank Becker, Erkan Baloglu, Margaret Lee, Michael Kauffman, Sharon Shacham,  and Yosef Landesman
110503-110516
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GATA3-induced vWF upregulation in the lung adenocarcinoma vasculature

GATA3-induced vWF upregulation in the lung adenocarcinoma vasculature

https://doi.org/10.18632/oncotarget.22806

Yinghua Xu, Silin Pan, Jing Liu, Fengyun Dong, Zuowang Cheng, Jinjin Zhang, Ruixia Qi, Qi Zang, Caiqing Zhang, Xia Wang, Jiandong Zhang, Fufang Wang, Thaddeus D. Allen,  and Ju Liu
110517-110529
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Early morphological change for predicting outcome in metastatic colorectal cancer after regorafenib

Early morphological change for predicting outcome in metastatic colorectal cancer after regorafenib

https://doi.org/10.18632/oncotarget.22807

Hiroyuki Arai, Kunihisa Miyakawa, Tadamichi Denda, Takuro Mizukami, Yoshiki Horie, Naoki Izawa, Mami Hirakawa, Takashi Ogura, Takashi Tsuda, Yu Sunakawa,  and Takako Eguchi Nakajima
110530-110539
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MicroRNA-128 suppresses paclitaxel-resistant lung cancer by inhibiting MUC1-C and BMI-1 in cancer stem cells

MicroRNA-128 suppresses paclitaxel-resistant lung cancer by inhibiting MUC1-C and BMI-1 in cancer stem cells

https://doi.org/10.18632/oncotarget.22818

Hyebin Koh, Hyeri Park, Nisansala Chandimali, Do Luong Huynh, Jiao Jiao Zhang, Mrinmoy Ghosh, Meeta Gera, Nameun Kim, Yesol Bak, Do-Young Yoon, Yang Ho Park, Taeho Kwon,  and Dong Kee Jeong
110540-110551
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LncRNA CRNDE promotes cell proliferation, invasion and migration by competitively binding miR-384 in papillary thyroid cancer

LncRNA CRNDE promotes cell proliferation, invasion and migration by competitively binding miR-384 in papillary thyroid cancer

https://doi.org/10.18632/oncotarget.22819

Honggang Sun, Liqin He, Lan Ma, Tao Lu, Jianguo Wei, Kejie Xie,  and Xingmu Wang
110552-110565
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Jujube leaf green tea extracts inhibits hepatocellular carcinoma cells by activating AMPK

Jujube leaf green tea extracts inhibits hepatocellular carcinoma cells by activating AMPK

https://doi.org/10.18632/oncotarget.22821

HX Liu, MQ Xu, SP Li, S Tian, MX Guo, JY Qi, CJ He,  and XS Zhao
110566-110575
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C21 steroid-enriched fraction refined from Marsdenia tenacissima inhibits hepatocellular carcinoma through the coordination of Hippo-Yap and PTEN-PI3K/AKT signaling pathways

C21 steroid-enriched fraction refined from Marsdenia tenacissima inhibits hepatocellular carcinoma through the coordination of Hippo-Yap and PTEN-PI3K/AKT signaling pathways

https://doi.org/10.18632/oncotarget.22833

Yu Zhang, Kaiqiang Li, Youmin Ying, Bingyu Chen, Ke Hao, Boxu Chen, Yu Zheng, Jianxin Lyu, Xiangming Tong, Xiaopan Chen, Ying Wan, Zhajun Zhan, Wei Zhang,  and Zhen Wang
110576-110591
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Melatonin up-regulates the expression of the GATA-4 transcription factor and increases testosterone secretion from Leydig cells through RORα signaling in an in vitro goat spermatogonial stem cell differentiation culture system

Melatonin up-regulates the expression of the GATA-4 transcription factor and increases testosterone secretion from Leydig cells through RORα signaling in an in vitro goat spermatogonial stem cell differentiation culture system

https://doi.org/10.18632/oncotarget.22855

Shou-Long Deng, Yan Zhang, Kun Yu, Xiu-Xia Wang, Su-Ren Chen, De-Ping Han, C. Yan Cheng, Zheng-Xing Lian,  and Yi-Xun Liu
110592-110605
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Meta-Analysis

Prognostic value of lymphocyte-to-monocyte ratio among Asian lung cancer patients: a systematic review and meta-analysis

Prognostic value of lymphocyte-to-monocyte ratio among Asian lung cancer patients: a systematic review and meta-analysis

https://doi.org/10.18632/oncotarget.20574

Wen Li, Guangzhi Ma, Qiang Wu, Yunfu Deng, Ya Liu,  and Jing Wang
110606-110613
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Association between rs3087243 and rs231775 polymorphism within the cytotoxic T-lymphocyte antigen 4 gene and Graves’ disease: a case/control study combined with meta-analyses

Association between rs3087243 and rs231775 polymorphism within the cytotoxic T-lymphocyte antigen 4 gene and Graves’ disease: a case/control study combined with meta-analyses

https://doi.org/10.18632/oncotarget.22702

Yaqin Tu, Guorun Fan, Yu Dai, Tianshu Zeng, Fei Xiao, Lulu Chen,  and Wen Kong
110614-110624
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Clinical Research Papers

Lymph node ratio determines the benefit of adjuvant radiotherapy in pathologically 3 or less lymph node-positive prostate cancer after radical prostatectomy: a population-based analysis with propensity-score matching

Lymph node ratio determines the benefit of adjuvant radiotherapy in pathologically 3 or less lymph node-positive prostate cancer after radical prostatectomy: a population-based analysis with propensity-score matching

https://doi.org/10.18632/oncotarget.22610

Yi-Jun Kim, Changhoon Song, Keun-Yong Eom, In Ah Kim,  and Jae-Sung Kim
110625-110634
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Reviews

Single nucleotide polymorphisms and cancer susceptibility

Single nucleotide polymorphisms and cancer susceptibility

https://doi.org/10.18632/oncotarget.22372

Na Deng, Heng Zhou, Hua Fan,  and Yuan Yuan
110635-110649
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F-box proteins in epigenetic regulation of cancer

F-box proteins in epigenetic regulation of cancer

https://doi.org/10.18632/oncotarget.22469

Jia Shen,  and Charles Spruck
110650-110655
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PKM2 in carcinogenesis and oncotherapy

PKM2 in carcinogenesis and oncotherapy

https://doi.org/10.18632/oncotarget.22529

Xia He, Suya Du, Tiantian Lei, Xiang Li, Yilong Liu, Hailian Wang, Rongsheng Tong,  and Yi Wang
110656-110670
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The regulatory roles of long non-coding RNAs in the development of chemoresistance in breast cancer

The regulatory roles of long non-coding RNAs in the development of chemoresistance in breast cancer

https://doi.org/10.18632/oncotarget.22577

Akshay Malhotra, Manju Jain, Hridayesh Prakash, Karen M. Vasquez,  and Aklank Jain
110671-110684
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LncRNAs and their role in cancer stem cells

LncRNAs and their role in cancer stem cells

https://doi.org/10.18632/oncotarget.22161

Shusen Chen, Jiamin Zhu, Feng Wang, Zhifeng Guan, Yangyang Ge, Xi Yang,  and Jing Cai
110685-110692
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Regulation of PD-1/PD-L1 pathway and resistance to PD-1/PDL1 blockade

Regulation of PD-1/PD-L1 pathway and resistance to PD-1/PDL1 blockade

https://doi.org/10.18632/oncotarget.22690

Jie Bai, Zhitao Gao, Xiang Li, Liang Dong, Weidong Han,  and Jing Nie
110693-110707
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Antioxidant agents against trichothecenes: new hints for oxidative stress treatment

Antioxidant agents against trichothecenes: new hints for oxidative stress treatment

https://doi.org/10.18632/oncotarget.22800

Qinghua Wu, Xu Wang, Eugenie Nepovimova, Yun Wang, Hualin Yang, Li Li, Xiujuan Zhang,  and Kamil Kuca
110708-110726
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Case Reports

Bendamustine plus rituximab is an effective first-line treatment in hairy cell leukemia variant: a report of three cases

Bendamustine plus rituximab is an effective first-line treatment in hairy cell leukemia variant: a report of three cases

https://doi.org/10.18632/oncotarget.21304

Andrea Visentin, Silvia Imbergamo, Federica Frezzato, Marco Pizzi, Roberta Bertorelle, Edoardo Scomazzon, Tamara Berno, Marcello Riva, Elisa Piva, Monica Facco, Francesco Piazza, Gianpietro Semenzato,  and Livio Trentin
110727-110731
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Corrections

Correction: Kinetic change of serum carcinoembryonic antigen can early predict progression in patients with metastatic non-small cell lung cancer during maintenance therapy with bevacizumab plus pemetrexed

Correction: Kinetic change of serum carcinoembryonic antigen can early predict progression in patients with metastatic non-small cell lung cancer during maintenance therapy with bevacizumab plus pemetrexed

https://doi.org/10.18632/oncotarget.23291

Nasha Zhang, Li Kong, Fang Shi, Wang Jing, Haiyong Wang, Ming Yang, Jinming Yu,  and Hui Zhu
110732-110732
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