p53 pathway dysfunction in AML: beyond TP53 mutations

Atg4 in autophagosome biogenesis

Loss of PACS-2 delays regeneration in DSS-induced colitis but does not affect the Apc^Min model of colorectal cancer

The PAX8 cistrome in epithelial ovarian cancer

Lipopolysaccharide induces acute bursal atrophy in broiler chicks by activating TLR4‑MAPK-NF-κB/AP-1 signaling

Genome-wide gene expression analysis in the amphioxus, Branchiostoma belcheri after poly (I: C) challenge using strand-specific RNA-seq

Regulatory T cells with a defect in inhibition on co-stimulation deteriorated primary biliary cholangitis

CysLT1 receptor antagonist alleviates pathogenesis of collagen-induced arthritis mouse model

The management of active surveillance in prostate cancer: validation of the Canary Prostate Active Surveillance Study risk calculator with the Spanish Urological Association Registry

Dual targeting of HER3 and MEK may overcome HER3-dependent drug-resistance of colon cancers

Efficacy and safety of dupilumab for the treatment of moderate-to-severe atopic dermatitis in adults

Retrospective investigation of retinoblastoma in Chinese patients

Curcumin downregulates the expression of Snail via suppressing Smad2 pathway to inhibit TGF-β1-induced epithelial-mesenchymal transitions in hepatoma cells

Development and validation of a machine learning-based predictive model to improve the prediction of inguinal status of anal cancer patients: A preliminary report

Mimicking the BIM BH3 domain overcomes resistance to EGFR tyrosine kinase inhibitors in EGFR-mutant non-small cell lung cancer

The AKT inhibitor triciribine in combination with paclitaxel has order-specific efficacy against Zfp217-induced breast cancer chemoresistance

Stathmin 1 expression predicts prognosis and benefits from adjuvant chemotherapy in patients with gallbladder carcinoma

Phosphorylation of Rab37 by protein kinase C alpha inhibits the exocytosis function and metastasis suppression activity of Rab37

NLRP3 inflammasome activation plays a carcinogenic role through effector cytokine IL-18 in lymphoma

Development of novel target modules for retargeting of UniCAR T cells to GD2 positive tumor cells

Aging increases the expression of lung CINCs and MCP-1 in senile patients with pneumonia

The relationship between DNA methylation and Reprimo gene expression in gastric cancer cells

Improving anti-melanoma effect of curcumin by biodegradable nanoparticles

Involvement of the oncogene B-cell lymphoma 6 in the fusion and differentiation process of trophoblastic cells of the placenta

Hyperglycemia combined Helicobacter pylori infection increases risk of synchronous colorectal adenoma and carotid artery plaque

Overexpression of miR-101 promotes TRAIL-induced mitochondrial apoptosis in papillary thyroid carcinoma by targeting c-met and MCL-1

Ultrasound molecular imaging with cRGD-PLGA-PFOB nanoparticles for liver fibrosis staging in a rat model

Therapeutic effects of adipose-derived mesenchymal stem cells against brain death-induced remote organ damage and post-heart transplant acute rejection

Downregulation of miR-221-3p and upregulation of its target gene PARP1 are prognostic biomarkers for triple negative breast cancer patients and associated with poor prognosis

TrkB promotes laryngeal cancer metastasis via activation PI3K/AKT pathway

Azacitidine combined with the selective FLT3 kinase inhibitor crenolanib disrupts stromal protection and inhibits expansion of residual leukemia-initiating cells in FLT3-ITD AML with concurrent epigenetic mutations

Dissect new mechanistic insights for geniposide efficacy on the hepatoprotection using multiomics approach

Trends in colorectal cancer mortality in hispanics: a SEER analysis

B-CAN: a resource sharing platform to improve the operation, visualization and integrated analysis of TCGA breast cancer data

Transcriptional response to hypoxic stress in melanoma and prognostic potential of GBE1 and BNIP3

Metformin improves nonalcoholic fatty liver disease in obese mice via down-regulation of apolipoprotein A5 as part of the AMPK/LXRα signaling pathway

Serum microRNA signatures and metabolomics have high diagnostic value in hepatocellular carcinoma

Systematic analysis reveals tumor-enhancing and -suppressing microRNAs in Drosophila epithelial tumors

Comparison of ALK status between primary and corresponding lymph node metastatic tumors in lung cancer patients

Improvement of anti-cancer drug efficacy via thermosensitive hydrogel in peritoneal carcinomatosis in gastric cancer

Association between MMP-3 polymorphisms among Chinese patients with osteonecrosis of the femoral head

CIPPN: computational identification of protein pupylation sites by using neural network

Matrine inhibits BCR/ABL mediated ERK/MAPK pathway in human leukemia cells

Nitric oxide is cytoprotective to breast cancer spheroids vulnerable to estrogen-induced apoptosis

Integrated analysis of chromosome copy number variation and gene expression in cervical carcinoma

Deletion lengthening at chromosomes 6q and 16q targets multiple tumor suppressor genes and is associated with an increasingly poor prognosis in prostate cancer

Therapeutic strategies and genetic profile comparisons in small cell carcinoma and large cell neuroendocrine carcinoma of the lung using next-generation sequencing

Ultrasound and clinicopathological features of papillary thyroid carcinomas with BRAF and TERT promoter mutations

Shexiang Tongxin dropping pill protects against isoproterenol-induced myocardial ischemia in vivo and in vitro

A novel dynamic model for predicting outcome in patients with hepatitis B virus related acute-on-chronic liver failure

Recipient bone marrow assimilates the myeloid/lymphoid reconstitution of distinct fetal hematopoietic stem cells

Increased risk of brain cancer incidence in stroke patients: a clinical case series, population-based and longitudinal follow-up study

Glucose impairs tamoxifen responsiveness modulating connective tissue growth factor in breast cancer cells

Tumour-microenvironmental blood flow determines a metabolomic signature identifying lysophospholipids and resolvin D as biomarkers in endometrial cancer patients

Tripterygium Wilfordii inhibits tonsillar IgA production by downregulating IgA class switching in IgA nephropathy

G6PD promotes renal cell carcinoma proliferation through positive feedback regulation of p-STAT3

GnRH agonist treatment for idiopathic central precocious puberty can improve final adult height in Chinese girls

Metformin sensitizes lung cancer cells to treatment by the tyrosine kinase inhibitor erlotinib

The relative change in regulatory T cells / T helper lymphocytes ratio as parameter for prediction of therapy efficacy in metastatic colorectal cancer patients

Shikonin induces ROS-based mitochondria-mediated apoptosis in colon cancer

Investigation of TCF7L2, LEP and LEPR polymorphisms with esophageal squamous cell carcinomas

Pyruvate kinase M2 phosphorylates H2AX and promotes genomic instability in human tumor cells

RA and ω-3 PUFA co-treatment activates autophagy in cancer cells

Targeting of CD122 enhances antitumor immunity by altering the tumor immune environment

Interleukin-22 participates in the inflammatory process of vitiligo

Histopathological, molecular, clinical and radiological characterization of rosette-forming glioneuronal tumor in the central nervous system

Mild hypothermia modulates the expression of nestin and caspase-3 in the sub-granular zone and improves neurological outcomes in rats with ischemic stroke

Inhibition of hepatocellular carcinoma growth by blockade of glycosphingolipid synthesis

Tanshinone IIA inhibits angiogenesis in human endothelial progenitor cells in vitro and in vivo

Intratumoral heterogeneity and TERT promoter mutations in progressive/higher-grade meningiomas

Serum amyloid a induces M2b-like macrophage polarization during liver inflammation

Overexpression of SCAMP3 is an indicator of poor prognosis in hepatocellular carcinoma

Induction of renal artery hyperresponsiveness by alpha1-adrenoceptor in hepatorenal syndrome

Androgen enhances the activity of ETS-1 and promotes the proliferation of HCC cells

APRIL promotes non-small cell lung cancer growth and metastasis by targeting ERK1/2 signaling

Ascl2 activation by YAP1/KLF5 ensures the self-renewability of colon cancer progenitor cells

Inhibitor repurposing reveals ALK, LTK, FGFR, RET and TRK kinases as the targets of AZD1480

Association between SOD1, CAT, GSHPX1 polymorphisms and the risk of inflammatory bowel disease in the Polish population

The anti-cancer effects and mechanisms of Scutellaria barbata D. Don on CL1-5 lung cancer cells

Dysregulated connexin 43 in HER2-positive drug resistant breast cancer cells enhances proliferation and migration

3D-structured illumination microscopy reveals clustered DNA double-strand break formation in widespread γH2AX foci after high LET heavy-ion particle radiation

XRCC1 serves as a potential prognostic indicator for clear cell renal cell carcinoma and inhibits its invasion and metastasis through suppressing MMP-2 and MMP-9

Detection of HPV related oropharyngeal cancer in oral rinse specimens

T-cell responses to KSHV infection: a systematic approach

Estrogen receptor signaling mediates leptin-induced growth of breast cancer cells via autophagy induction

Systematic assessment of cervical cancer initiation and progression uncovers genetic panels for deep learning-based early diagnosis and proposes novel diagnostic and prognostic biomarkers

Copy number variations in atypical fibroxanthomas and pleomorphic dermal sarcomas

Elevated red blood cell distribution width predicts poor prognosis in hilar cholangiocarcinoma

Acute nutritional stress during pregnancy affects placental efficiency, fetal growth and adult glucose homeostasis

Notoginsenoside R7 suppresses cervical cancer via PI3K/PTEN/Akt/mTOR signaling

Associations of plasma hepcidin with mortality risk in patients with coronary artery disease

Long non-coding RNA HOXA11-AS promotes the proliferation HCC cells by epigenetically silencing DUSP5

Optimizing prognosis-related key miRNA-target interactions responsible for cancer metastasis

A proteomic approach for the identification of biomarkers in endometrial cancer uterine aspirate

MiR-520f promotes cell aggressiveness by regulating fibroblast growth factor 16 in hepatocellular carcinoma

Fluorescence-guided surgery for cancer patients: a proof of concept study on human xenografts in mice and spontaneous tumors in pets

Neat1 in hematopoietic stem cells

Proteomic approach toward determining the molecular background of pazopanib resistance in synovial sarcoma

TRIB2 contributes to cisplatin resistance in small cell lung cancer

The synergistic antitumor effect of arsenic trioxide combined with cytotoxic T cells in pulmonary metastasis model of colon cancer

Experimental verification of a 3D in vivo dose monitoring system based on EPID

LRP6 promotes invasion and metastasis of colorectal cancer through cytoskeleton dynamics

Tumor gene expression data classification via sample expansion-based deep learning

Notch signaling negatively regulates BMP9-induced osteogenic differentiation of mesenchymal progenitor cells by inhibiting JunB expression

Coregulator profiling of the glucocorticoid receptor in lymphoid malignancies

Progranulin derived engineered protein Atsttrin suppresses TNF-α-mediated inflammation in intervertebral disc degenerative disease

Impact of epidermal growth factor receptor sensitizing mutations on outcomes of patients with non-small cell lung cancer treated with definitive thoracic radiation therapy: a systematic review and meta-analysis

Efficacy of sorafenib in patients with hepatocellular carcinoma after resection: a meta-analysis

Clinicopathological significance of CHFR methylation in non-small cell lung cancer: a systematic review and meta-analysis

Systematic review and meta-analysis of the prognostic value of CXCR2 in solid tumor patients

Predictive value of post-procedural early (within 24 h) increase in cystatin C for contrast-induced acute kidney injury and mortality following coronary angiography or intervention

Prognostic nomogram for acute-on-chronic hepatitis B liver failure

Predicting clinically significant prostate cancer based on pre-operative patient profile and serum biomarkers

Microwave ablation versus radiofrequency ablation for the treatment of pulmonary tumors

Molecular characterization of circulating tumor cells in lung cancer: moving beyond enumeration