Oncotarget

Vol 8, No 65

December 12, 2017

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About The Cover

The cover for issue 65 of Oncotarget features Figure 6C, "Schematic representation of SLPI’s effects on the regulation of the Rb/FoxM1 complex," from Kozin, et al.

Table of Contents

Editorial

On the hunt for B-cell lymphoblastic leukemia-initiating stem cells

On the hunt for B-cell lymphoblastic leukemia-initiating stem cells

https://doi.org/10.18632/oncotarget.22578

Bartosch Wojcik, Fabian Lang,  and Michael A. Rieger
108286-108287
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p53 pathway dysfunction in AML: beyond TP53 mutations

p53 pathway dysfunction in AML: beyond TP53 mutations

https://doi.org/10.18632/oncotarget.22713

Sean M. Post, Steven M. Kornblau,  and Alfonso Quintás-Cardama
108288-108289
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Atg4 in autophagosome biogenesis

Atg4 in autophagosome biogenesis

https://doi.org/10.18632/oncotarget.22714

Jana Sánchez-Wandelmer,  and Fulvio Reggiori
108290-108291
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Priority Research Papers

Secretory leukocyte protease inhibitor (SLPI) as a potential target for inhibiting metastasis of triple-negative breast cancers

Secretory leukocyte protease inhibitor (SLPI) as a potential target for inhibiting metastasis of triple-negative breast cancers

https://doi.org/10.18632/oncotarget.22660

Sergey V. Kozin, Nir Maimon, Rong Wang, Nisha Gupta, Lance Munn, Rakesh K. Jain,  and Igor Garkavtsev
108292-108302
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Loss of PACS-2 delays regeneration in DSS-induced colitis but does not affect the ApcMin model of colorectal cancer

Loss of PACS-2 delays regeneration in DSS-induced colitis but does not affect the ApcMin model of colorectal cancer

https://doi.org/10.18632/oncotarget.22661

Sarah L. Dombernowsky, Jeanette Schwarz, Jacob Samsøe-Petersen, Reidar Albrechtsen, Kim B. Jensen, Gary Thomas,  and Marie Kveiborg
108303-108315
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The PAX8 cistrome in epithelial ovarian cancer

The PAX8 cistrome in epithelial ovarian cancer

https://doi.org/10.18632/oncotarget.22718

Emily K. Adler, Rosario I. Corona, Janet M. Lee, Norma Rodriguez-Malave, Paulette Mhawech-Fauceglia, Heidi Sowter, Dennis J. Hazelett, Kate Lawrenson,  and Simon A. Gayther
108316-108332
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Research Papers: Pathology

Clinical role and biological function of CDK5 in hepatocellular carcinoma: A study based on immunohistochemistry, RNA-seq and in vitro investigation

Clinical role and biological function of CDK5 in hepatocellular carcinoma: A study based on immunohistochemistry, RNA-seq and in vitro investigation

https://doi.org/10.18632/oncotarget.22659

Rui Zhang, Peng Lin, Hong Yang, Yun He, Yi-Wu Dang, Zhen-Bo Feng,  and Gang Chen
108333-108354
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Research Papers: Immunology

The shared and specific mechanism of four autoimmune diseases

The shared and specific mechanism of four autoimmune diseases

https://doi.org/10.18632/oncotarget.19383

Meiwei Luan, Zhenwei Shang, Yanbo Teng, Xinren Chen, Mingming Zhang, Hongchao Lv,  and Ruijie Zhang
108355-108374
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Lipopolysaccharide induces acute bursal atrophy in broiler chicks by activating TLR4‑MAPK-NF-κB/AP-1 signaling

Lipopolysaccharide induces acute bursal atrophy in broiler chicks by activating TLR4‑MAPK-NF-κB/AP-1 signaling

https://doi.org/10.18632/oncotarget.19964

Abdur Rahman Ansari, Ning-Ya Li, Zhi-Jian Sun, Hai-Bo Huang, Xing Zhao, Lei Cui, Ya-Fang Hu, Ju-Ming Zhong, Niel A. Karrow,  and Hua-Zhen Liu
108375-108391
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Genome-wide gene expression analysis in the amphioxus, Branchiostoma belcheri after poly (I: C) challenge using strand-specific RNA-seq

Genome-wide gene expression analysis in the amphioxus, Branchiostoma belcheri after poly (I: C) challenge using strand-specific RNA-seq

https://doi.org/10.18632/oncotarget.21553

Qi-Lin Zhang, Zheng-Qing Xie, Ming-Zhong Liang, Bang Luo, Xiu-Qiang Wang,  and Jun-Yuan Chen
108392-108405
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Regulatory T cells with a defect in inhibition on co-stimulation deteriorated primary biliary cholangitis

Regulatory T cells with a defect in inhibition on co-stimulation deteriorated primary biliary cholangitis

https://doi.org/10.18632/oncotarget.22658

Jianing Chen, Xianliang Hou, Hongyu Jia, Guangying Cui, Zhongwen Wu, Lin Wang, Chong Lu, Wei Wu, Yingfeng Wei, Toshimitsu Uede, Lanjuan Li, Zhexiong Lian,  and Hongyan Diao
108406-108417
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CysLT1 receptor antagonist alleviates pathogenesis of collagen-induced arthritis mouse model

CysLT1 receptor antagonist alleviates pathogenesis of collagen-induced arthritis mouse model

https://doi.org/10.18632/oncotarget.22664

Minwen Xu, Ruiyun Hong, Xiaoli Zhang, Hailin Zou, Yi Zhang, Zhiping Hou,  and Liefeng Wang
108418-108429
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Research Papers

Energy metabolism in glioblastoma stem cells: PPARα a metabolic adaptor to intratumoral microenvironment

Energy metabolism in glioblastoma stem cells: PPARα a metabolic adaptor to intratumoral microenvironment

https://doi.org/10.18632/oncotarget.19086

Alessia Fidoamore, Loredana Cristiano, Chiara Laezza, Renato Galzio, Elisabetta Benedetti, Benedetta Cinque, Andrea Antonosante, Michele d’Angelo, Vanessa Castelli, Maria Grazia Cifone, Rodolfo Ippoliti, Antonio Giordano,  and Annamaria Cimini
108430-108450
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The management of active surveillance in prostate cancer: validation of the Canary Prostate Active Surveillance Study risk calculator with the Spanish Urological Association Registry

The management of active surveillance in prostate cancer: validation of the Canary Prostate Active Surveillance Study risk calculator with the Spanish Urological Association Registry

https://doi.org/10.18632/oncotarget.21984

Ángel Borque-Fernando, José Rubio-Briones, Luis Mariano Esteban, Argimiro Collado-Serra, Yoni Pallás-Costa, Pedro Ángel López-González, Jorge Huguet-Pérez, José Ignacio Sanz-Vélez, Jesús Manuel Gil-Fabra, Enrique Gómez-Gómez, Cristina Quicios-Dorado, Lluis Fumadó, Sara Martínez-Breijo, Juan Soto-Villalba,  and on behalf of the PIEM Active Surveillance Study Group
108451-108462
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Dual targeting of HER3 and MEK may overcome HER3-dependent drug-resistance of colon cancers

Dual targeting of HER3 and MEK may overcome HER3-dependent drug-resistance of colon cancers

https://doi.org/10.18632/oncotarget.11400

Giulia Bon, Rossella Loria, Carla Azzurra Amoreo, Alessandra Verdina, Isabella Sperduti, Arianna Mastrofrancesco, Silvia Soddu, Maria Grazia Diodoro, Marcella Mottolese, Matilde Todaro, Giorgio Stassi, Michele Milella, Ruggero De Maria,  and Rita Falcioni
108463-108479
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Efficacy and safety of dupilumab for the treatment of moderate-to-severe atopic dermatitis in adults

Efficacy and safety of dupilumab for the treatment of moderate-to-severe atopic dermatitis in adults

https://doi.org/10.18632/oncotarget.22499

Xinghua Xu, Yi Zheng, Xin Zhang, Yanling He,  and Chengxin Li
108480-108491
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Retrospective investigation of retinoblastoma in Chinese patients

Retrospective investigation of retinoblastoma in Chinese patients

https://doi.org/10.18632/oncotarget.18174

Liwen Jin, Wei Zhang, Hong Pan, Tengyan Li, Beihong Liu, Junyang Zhao,  and Binbin Wang
108492-108497
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Curcumin downregulates the expression of Snail via suppressing Smad2 pathway to inhibit TGF-β1-induced epithelial-mesenchymal transitions in hepatoma cells

Curcumin downregulates the expression of Snail via suppressing Smad2 pathway to inhibit TGF-β1-induced epithelial-mesenchymal transitions in hepatoma cells

https://doi.org/10.18632/oncotarget.22590

Meng-Ting Cao, Hui-Fang Liu, Zhi-Gang Liu, Ping Xiao, Jing-Jing Chen, Yuan Tan, Xiao-Xin Jiang, Zhi-Chao Jiang, Yu Qiu, Hong-Jun Huang, Qiu-Gui Zhang,  and Guan-Min Jiang
108498-108508
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Development and validation of a machine learning-based predictive model to improve the prediction of inguinal status of anal cancer patients: A preliminary report

Development and validation of a machine learning-based predictive model to improve the prediction of inguinal status of anal cancer patients: A preliminary report

https://doi.org/10.18632/oncotarget.10749

Berardino De Bari, Mauro Vallati, Roberto Gatta, Laëtitia Lestrade, Stefania Manfrida, Christian Carrie,  and Vincenzo Valentini
108509-108521
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Mimicking the BIM BH3 domain overcomes resistance to EGFR tyrosine kinase inhibitors in EGFR-mutant non-small cell lung cancer

Mimicking the BIM BH3 domain overcomes resistance to EGFR tyrosine kinase inhibitors in EGFR-mutant non-small cell lung cancer

https://doi.org/10.18632/oncotarget.19411

Jinjing Xia, Hao Bai, Bo Yan, Rong Li, Minhua Shao, Liwen Xiong,  and Baohui Han
108522-108533
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The AKT inhibitor triciribine in combination with paclitaxel has order-specific efficacy against Zfp217-induced breast cancer chemoresistance

The AKT inhibitor triciribine in combination with paclitaxel has order-specific efficacy against Zfp217-induced breast cancer chemoresistance

https://doi.org/10.18632/oncotarget.19308

Christopher D. Suarez, Junmin Wu, Sunil S. Badve, Joseph A. Sparano, William Kaliney,  and Laurie E. Littlepage
108534-108547
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Stathmin 1 expression predicts prognosis and benefits from adjuvant chemotherapy in patients with gallbladder carcinoma

Stathmin 1 expression predicts prognosis and benefits from adjuvant chemotherapy in patients with gallbladder carcinoma

https://doi.org/10.18632/oncotarget.19625

Xiaobo Bo, Jie Wang, Qiang Fu, Yueqi Wang, Houbao Liu,  and Jiejie Xu
108548-108555
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Phosphorylation of Rab37 by protein kinase C alpha inhibits the exocytosis function and metastasis suppression activity of Rab37

Phosphorylation of Rab37 by protein kinase C alpha inhibits the exocytosis function and metastasis suppression activity of Rab37

https://doi.org/10.18632/oncotarget.20998

Hong-Tai Tzeng, Tsung-Hsin Li, Yen-An Tang, Chung-Han Tsai, Pei-Jung Frank Lu, Wu-Wei Lai, Chi-Wu Chiang,  and Yi-Ching Wang
108556-108570
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NLRP3 inflammasome activation plays a carcinogenic role through effector cytokine IL-18 in lymphoma

NLRP3 inflammasome activation plays a carcinogenic role through effector cytokine IL-18 in lymphoma

https://doi.org/10.18632/oncotarget.21010

Xia Zhao, Chen Zhang, Mingqiang Hua, Ruiqing Wang, Chaoqin Zhong, Jie Yu, Fengjiao Han, Na He, Yanan Zhao, Guoqiang Liu, Ni Zheng, Chunyan Ji,  and Daoxin Ma
108571-108583
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Development of novel target modules for retargeting of UniCAR T cells to GD2 positive tumor cells

Development of novel target modules for retargeting of UniCAR T cells to GD2 positive tumor cells

https://doi.org/10.18632/oncotarget.21017

Nicola Mitwasi, Anja Feldmann, Ralf Bergmann, Nicole Berndt, Claudia Arndt, Stefanie Koristka, Alexandra Kegler, Justyna Jureczek, Anja Hoffmann, Armin Ehninger, Marc Cartellieri, Susann Albert, Claudia Rossig, Gerhard Ehninger, Jens Pietzsch, Jörg Steinbach,  and Michael Bachmann
108584-108603
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Aging increases the expression of lung CINCs and MCP-1 in senile patients with pneumonia

Aging increases the expression of lung CINCs and MCP-1 in senile patients with pneumonia

https://doi.org/10.18632/oncotarget.21285

Wei Li, Cheng Ding,  and Shaojun Yin
108604-108609
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The relationship between DNA methylation and Reprimo gene expression in gastric cancer cells

The relationship between DNA methylation and Reprimo gene expression in gastric cancer cells

https://doi.org/10.18632/oncotarget.21296

Junzhong Lai, Hanze Wang, Qianping Luo, Shanlu Huang, Shujin Lin, Yansong Zheng,  and Qi Chen
108610-108623
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Improving anti-melanoma effect of curcumin by biodegradable nanoparticles

Improving anti-melanoma effect of curcumin by biodegradable nanoparticles

https://doi.org/10.18632/oncotarget.20585

Bilan Wang, Xiaoxiao Liu, Yan Teng, Ting Yu, Junli Chen, Yuzhu Hu, Na Liu, Lingli Zhang,  and Yangmei Shen
108624-108642
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Involvement of the oncogene B-cell lymphoma 6 in the fusion and differentiation process of trophoblastic cells of the placenta

Involvement of the oncogene B-cell lymphoma 6 in the fusion and differentiation process of trophoblastic cells of the placenta

https://doi.org/10.18632/oncotarget.20586

Britta Jasmer, Cornelia Muschol-Steinmetz, Nina-Naomi Kreis, Alexandra Friemel, Ulrikke Kielland-Kaisen, Dörthe Brüggmann, Lukas Jennewein, Roman Allert, Christine Solbach, Juping Yuan,  and Frank Louwen
108643-108654
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Hyperglycemia combined Helicobacter pylori infection increases risk of synchronous colorectal adenoma and carotid artery plaque

Hyperglycemia combined Helicobacter pylori infection increases risk of synchronous colorectal adenoma and carotid artery plaque

https://doi.org/10.18632/oncotarget.22094

Kuang-Chun Hu, Ming-Shiang Wu, Cheng-Hsin Chu, Horng-Yuan Wang, Shee-Chan Lin, Helen L. Po, Ming-Jong Bair, Chuan-Chuan Liu, Tung-Hung Su, Chi-Ling Chen, Chun-Jen Liu,  and Shou-Chuan Shih
108655-108664
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Overexpression of miR-101 promotes TRAIL-induced mitochondrial apoptosis in papillary thyroid carcinoma by targeting c-met and MCL-1

Overexpression of miR-101 promotes TRAIL-induced mitochondrial apoptosis in papillary thyroid carcinoma by targeting c-met and MCL-1

https://doi.org/10.18632/oncotarget.21215

Jie Zhu,  and Zhenjie Li
108665-108675
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Ultrasound molecular imaging with cRGD-PLGA-PFOB nanoparticles for liver fibrosis staging in a rat model

Ultrasound molecular imaging with cRGD-PLGA-PFOB nanoparticles for liver fibrosis staging in a rat model

https://doi.org/10.18632/oncotarget.21358

Jiqing Xuan, Yuli Chen, Leilei Zhu, Yuan Guo, Liming Deng, Yuanyi Zheng, Zhaoxia Wang, Zhigang Wang,  and Meng Ao
108676-108691
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Therapeutic effects of adipose-derived mesenchymal stem cells against brain death-induced remote organ damage and post-heart transplant acute rejection

Therapeutic effects of adipose-derived mesenchymal stem cells against brain death-induced remote organ damage and post-heart transplant acute rejection

https://doi.org/10.18632/oncotarget.21433

Hon-Kan Yip, Mel S. Lee, Cheuk-Kwan Sun, Kuan-Hung Chen, Han-Tan Chai, Pei-Hsun Sung, Kun-Chen Lin, Sheung-Fat Ko, Chun-Man Yuen, Chu-Feng Liu, Pei-Lin Shao,  and Fan-Yen Lee
108692-108711
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Downregulation of miR-221-3p and upregulation of its target gene PARP1 are prognostic biomarkers for triple negative breast cancer patients and associated with poor prognosis

Downregulation of miR-221-3p and upregulation of its target gene PARP1 are prognostic biomarkers for triple negative breast cancer patients and associated with poor prognosis

https://doi.org/10.18632/oncotarget.21561

Ling Deng, Qianqian Lei, Yu Wang, Zhu Wang, Guiqin Xie, Xiaorong Zhong, Yanping Wang, Nianyong Chen, Yan Qiu, Tianjie Pu, Hong Bu,  and Hong Zheng
108712-108725
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TrkB promotes laryngeal cancer metastasis via activation PI3K/AKT pathway

TrkB promotes laryngeal cancer metastasis via activation PI3K/AKT pathway

https://doi.org/10.18632/oncotarget.21711

Liang Jiang, Zhihai Wang, Chuan Liu, Zhitao Gong, Yucheng Yang, Houyong Kang, Yanshi Li,  and Guohua Hu
108726-108737
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Azacitidine combined with the selective FLT3 kinase inhibitor crenolanib disrupts stromal protection and inhibits expansion of residual leukemia-initiating cells in FLT3-ITD AML with concurrent epigenetic mutations

Azacitidine combined with the selective FLT3 kinase inhibitor crenolanib disrupts stromal protection and inhibits expansion of residual leukemia-initiating cells in FLT3-ITD AML with concurrent epigenetic mutations

https://doi.org/10.18632/oncotarget.21877

Anne-Kathrin Garz, Saskia Wolf, Sonja Grath, Verena Gaidzik, Stefan Habringer, Binje Vick, Martina Rudelius, Christoph Ziegenhain, Sylvia Herold, Marie-Theresa Weickert, Martha Smets, Christian Peschel, Robert A.J. Oostendorp, Sebastian Bultmann, Irmela Jeremias, Christian Thiede, Konstanze Döhner, Ulrich Keller,  and Katharina S. Götze
108738-108759
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Dissect new mechanistic insights for geniposide efficacy on the hepatoprotection using multiomics approach

Dissect new mechanistic insights for geniposide efficacy on the hepatoprotection using multiomics approach

https://doi.org/10.18632/oncotarget.21897

Shi Qiu, Aihua Zhang, Tianlei Zhang, Hui Sun, Yu Guan, Guangli Yan,  and Xijun Wang
108760-108770
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Trends in colorectal cancer mortality in hispanics: a SEER analysis

Trends in colorectal cancer mortality in hispanics: a SEER analysis

https://doi.org/10.18632/oncotarget.21938

Afsaneh Barzi, Dongyun Yang, Sayedamin Mostofizadeh,  and Heinz-Josef Lenz
108771-108777
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B-CAN: a resource sharing platform to improve the operation, visualization and integrated analysis of TCGA breast cancer data

B-CAN: a resource sharing platform to improve the operation, visualization and integrated analysis of TCGA breast cancer data

https://doi.org/10.18632/oncotarget.21947

Can-Hong Wen, Shao-Min Ou, Xiao-Bo Guo, Chen-Feng Liu, Yan-Bo Shen, Na You, Wei-Hong Cai, Wen-Jun Shen, Xue-Qin Wang,  and Hai-Zhu Tan
108778-108785
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Transcriptional response to hypoxic stress in melanoma and prognostic potential of GBE1 and BNIP3

Transcriptional response to hypoxic stress in melanoma and prognostic potential of GBE1 and BNIP3

https://doi.org/10.18632/oncotarget.22150

Stéphanie Buart, Stéphane Terry, Muhammad Z. Noman, Emilie Lanoy, Céline Boutros, Paul Fogel, Philippe Dessen, Guillaume Meurice, Yann Gaston-Mathé, Philippe Vielh, Séverine Roy, Emilie Routier, Virginie Marty, Sophie Ferlicot, Luc Legrès, Morad El. Bouchtaoui, Nyam Kamsu-Kom, Jane Muret, Eric Deutsch, Alexander Eggermont, Jean-Charles Soria, Caroline Robert,  and Salem Chouaib
108786-108801
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Metformin improves nonalcoholic fatty liver disease in obese mice via down-regulation of apolipoprotein A5 as part of the AMPK/LXRα signaling pathway

Metformin improves nonalcoholic fatty liver disease in obese mice via down-regulation of apolipoprotein A5 as part of the AMPK/LXRα signaling pathway

https://doi.org/10.18632/oncotarget.22163

Min-Jie Lin, Wen Dai, Melanie J. Scott, Rong Li, Yi-Qi Zhang, Yang Yang, Lu-Zhu Chen,  and Xian-Sheng Huang
108802-108809
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Serum microRNA signatures and metabolomics have high diagnostic value in hepatocellular carcinoma

Serum microRNA signatures and metabolomics have high diagnostic value in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.22224

Hai-Ning Liu, Hao Wu, Yan-Jie Chen, Yu-Jen Tseng, Enkhnaran Bilegsaikhan, Ling Dong, Xi-Zhong Shen,  and Tao-Tao Liu
108810-108824
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Systematic analysis reveals tumor-enhancing and -suppressing microRNAs in Drosophila epithelial tumors

Systematic analysis reveals tumor-enhancing and -suppressing microRNAs in Drosophila epithelial tumors

https://doi.org/10.18632/oncotarget.22226

Zhiqiang Shu, Yi-Chun Huang, William H. Palmer, Yoichiro Tamori, Gengqiang Xie, Hui Wang, Nan Liu,  and Wu-Min Deng
108825-108839
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Comparison of ALK status between primary and corresponding lymph node metastatic tumors in lung cancer patients

Comparison of ALK status between primary and corresponding lymph node metastatic tumors in lung cancer patients

https://doi.org/10.18632/oncotarget.22294

Qiqi Gao, Honghai Ma, Bo Wang, Yake Yao, Jianya Zhou,  and Jianying Zhou
108840-108847
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Improvement of anti-cancer drug efficacy via thermosensitive hydrogel in peritoneal carcinomatosis in gastric cancer

Improvement of anti-cancer drug efficacy via thermosensitive hydrogel in peritoneal carcinomatosis in gastric cancer

https://doi.org/10.18632/oncotarget.22312

Tae-Su Han, Keun Hur, Boram Choi, Ji-Yeon Lee, Sun-Ju Byeon, Jimin Min, Jieun Yu, Jung-Kyo Cho, Jimin Hong, Hyuk-Joon Lee, Seong-Ho Kong, Woo-Ho Kim, Kazuyoshi Yanagihara, Soo-Chang Song,  and Han-Kwang Yang
108848-108858
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Association between MMP-3 polymorphisms among Chinese patients with osteonecrosis of the femoral head

Association between MMP-3 polymorphisms among Chinese patients with osteonecrosis of the femoral head

https://doi.org/10.18632/oncotarget.22313

Yuxin Qi, Yong Zhu, Yuju Cao, Huiqiang Wu, Mingqi Sun, Hao Wu, Linlin Pan, Guoqiang Wang,  and Jianzhong Wang
108859-108866
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CIPPN: computational identification of protein pupylation sites by using neural network

CIPPN: computational identification of protein pupylation sites by using neural network

https://doi.org/10.18632/oncotarget.22335

Wenzheng Bao, Zhu-Hong You,  and De-Shuang Huang
108867-108879
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Matrine inhibits BCR/ABL mediated ERK/MAPK pathway in human leukemia cells

Matrine inhibits BCR/ABL mediated ERK/MAPK pathway in human leukemia cells

https://doi.org/10.18632/oncotarget.22353

Lingdi Ma, Zhenyu Xu, Jian Wang, Zhichao Zhu, Guibin Lin, Lijia Jiang, Xuzhang Lu,  and Chang Zou
108880-108889
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Nitric oxide is cytoprotective to breast cancer spheroids vulnerable to estrogen-induced apoptosis

Nitric oxide is cytoprotective to breast cancer spheroids vulnerable to estrogen-induced apoptosis

https://doi.org/10.18632/oncotarget.21610

Yana Shafran, Naomi Zurgil, Orit Ravid-Hermesh, Maria Sobolev, Elena Afrimzon, Yaron Hakuk, Asher Shainberg,  and Mordechai Deutsch
108890-108911
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Integrated analysis of chromosome copy number variation and gene expression in cervical carcinoma

Integrated analysis of chromosome copy number variation and gene expression in cervical carcinoma

https://doi.org/10.18632/oncotarget.22403

Deng Yan, Song Yi, Wang Chi Chiu, Liu Gui Qin, Wong Hoi Kin, Chung Tony Kwok Hung, Han Linxiao, Choy Kwong Wai, Sui Yi, Yang Tao,  and Tang Tao
108912-108922
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Deletion lengthening at chromosomes 6q and 16q targets multiple tumor suppressor genes and is associated with an increasingly poor prognosis in prostate cancer

Deletion lengthening at chromosomes 6q and 16q targets multiple tumor suppressor genes and is associated with an increasingly poor prognosis in prostate cancer

https://doi.org/10.18632/oncotarget.22408

Martina Kluth, Simon Jung, Omar Habib, Mina Eshagzaiy, Anna Heinl, Nina Amschler, Sawinee Masser, Malte Mader, Frederic Runte, Philipp Barow, Sohall Frogh, Jazan Omari, Christina Möller-Koop, Claudia Hube-Magg, Joachim Weischenfeldt, Jan Korbel, Stefan Steurer, Till Krech, Hartwig Huland, Markus Graefen, Sarah Minner, Guido Sauter, Thorsten Schlomm,  and Ronald Simon
108923-108935
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Therapeutic strategies and genetic profile comparisons in small cell carcinoma and large cell neuroendocrine carcinoma of the lung using next-generation sequencing

Therapeutic strategies and genetic profile comparisons in small cell carcinoma and large cell neuroendocrine carcinoma of the lung using next-generation sequencing

https://doi.org/10.18632/oncotarget.22426

Masaoki Ito, Yoshihiro Miyata, Shoko Hirano, Shingo Kimura, Fumiko Irisuna, Kyoko Ikeda, Kei Kushitani, Yasuhiro Tsutani, Daisuke Ueda, Norifumi Tsubokawa, Yukio Takeshima,  and Morihito Okada
108936-108945
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Ultrasound and clinicopathological features of papillary thyroid carcinomas with BRAF and TERT promoter mutations

Ultrasound and clinicopathological features of papillary thyroid carcinomas with BRAF and TERT promoter mutations

https://doi.org/10.18632/oncotarget.22430

Soo Yeon Hahn, Tae Hyuk Kim, Chang Seok Ki, Sun Wook Kim, Soohyun Ahn, Jung Hee Shin,  and Jae Hoon Chung
108946-108957
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Shexiang Tongxin dropping pill protects against isoproterenol-induced myocardial ischemia in vivo and in vitro

Shexiang Tongxin dropping pill protects against isoproterenol-induced myocardial ischemia in vivo and in vitro

https://doi.org/10.18632/oncotarget.22440

Jianyong Qi, Wenjun Pan, Yafang Tan, Jiaru Luo, Dancai Fan, Juan Yu, Jiashin Wu,  and Minzhou Zhang
108958-108969
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A novel dynamic model for predicting outcome in patients with hepatitis B virus related acute-on-chronic liver failure

A novel dynamic model for predicting outcome in patients with hepatitis B virus related acute-on-chronic liver failure

https://doi.org/10.18632/oncotarget.22447

Ran Xue, Zhonghui Duan, Haixia Liu, Li Chen, Hongwei Yu, Meixin Ren, Yueke Zhu, Chenggang Jin, Tao Han, Zhiliang Gao,  and Qinghua Meng
108970-108980
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Recipient bone marrow assimilates the myeloid/lymphoid reconstitution of distinct fetal hematopoietic stem cells

Recipient bone marrow assimilates the myeloid/lymphoid reconstitution of distinct fetal hematopoietic stem cells

https://doi.org/10.18632/oncotarget.22479

Xiao-Lin Guo, Lei Chu, Fang Ke, Li-Li Mu, Zhen Li, Jie-Jing Cai, Huai-Fang Li,  and Deng-Li Hong
108981-108988
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Increased risk of brain cancer incidence in stroke patients: a clinical case series, population-based and longitudinal follow-up study

Increased risk of brain cancer incidence in stroke patients: a clinical case series, population-based and longitudinal follow-up study

https://doi.org/10.18632/oncotarget.22480

Chih-Wei Chen, Tain-Junn Cheng, Chung-Han Ho, Jhi-Joung Wang, Shih-Feng Weng, Ya-Chin Hou, Hung-Chi Cheng, Chung-Ching Chio, Yan-Shen Shan,  and Wen-Tsan Chang
108989-108999
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Glucose impairs tamoxifen responsiveness modulating connective tissue growth factor in breast cancer cells

Glucose impairs tamoxifen responsiveness modulating connective tissue growth factor in breast cancer cells

https://doi.org/10.18632/oncotarget.22552

Maria Rosaria Ambrosio, Vittoria D’Esposito, Valerio Costa, Domenico Liguoro, Francesca Collina, Monica Cantile, Nella Prevete, Carmela Passaro, Giusy Mosca, Michelino De Laurentiis, Maurizio Di Bonito, Gerardo Botti, Renato Franco, Francesco Beguinot, Alfredo Ciccodicola,  and Pietro Formisano
109000-109017
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Tumour-microenvironmental blood flow determines a metabolomic signature identifying lysophospholipids and resolvin D as biomarkers in endometrial cancer patients

Tumour-microenvironmental blood flow determines a metabolomic signature identifying lysophospholipids and resolvin D as biomarkers in endometrial cancer patients

https://doi.org/10.18632/oncotarget.22558

Núria Eritja, Mariona Jové, Kristine Eldevik Fasmer, Sònia Gatius, Manuel Portero-Otin, Jone Trovik, Camilla Krakstad, Joaquim Sol, Reinald Pamplona, Ingfrid S. Haldorsen,  and Xavier Matias-Guiu
109018-109026
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Tripterygium Wilfordii inhibits tonsillar IgA production by downregulating IgA class switching in IgA nephropathy

Tripterygium Wilfordii inhibits tonsillar IgA production by downregulating IgA class switching in IgA nephropathy

https://doi.org/10.18632/oncotarget.22561

Huining Li, Dan Kong, Yang Xu, Xiaomei Li, Guodong Yao, Kexin Chen, Qi You, Qingtao Shi, Lei Zhang, Xin Wang, Dawei Yuan, Shusheng Miao, Jingshu Geng, Xiaoming Jin,  and Hongxue Meng
109027-109042
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

G6PD promotes renal cell carcinoma proliferation through positive feedback regulation of p-STAT3

G6PD promotes renal cell carcinoma proliferation through positive feedback regulation of p-STAT3

https://doi.org/10.18632/oncotarget.22566

Qiao Zhang, Zhe Yang, Qiaoqiao Han, Honggang Bai, Yanling Wang, Xiaojia Yi, Zihan Yi, Lijuan Yang, Lu Jiang, Xin Song, Yingmin Kuang,  and Yuechun Zhu
109043-109060
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GnRH agonist treatment for idiopathic central precocious puberty can improve final adult height in Chinese girls

GnRH agonist treatment for idiopathic central precocious puberty can improve final adult height in Chinese girls

https://doi.org/10.18632/oncotarget.22568

Yanqin Ying, Jing Tang, Wei Chen, Zemin Cai,  and Wan Ting Niu
109061-109067
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Metformin sensitizes lung cancer cells to treatment by the tyrosine kinase inhibitor erlotinib

Metformin sensitizes lung cancer cells to treatment by the tyrosine kinase inhibitor erlotinib

https://doi.org/10.18632/oncotarget.22596

Xiaofei Wang, Keqiang Chen, Ying Yu, Yi Xiang, Jae Hong Kim, Wanghua Gong, Jiaqiang Huang, Guochao Shi, Qingyun Li, Min Zhou, Thomas Sayers, Poonam Tewary, Beili Gao,  and Ji Ming Wang
109068-109078
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The relative change in regulatory T cells / T helper lymphocytes ratio as parameter for prediction of therapy efficacy in metastatic colorectal cancer patients

The relative change in regulatory T cells / T helper lymphocytes ratio as parameter for prediction of therapy efficacy in metastatic colorectal cancer patients

https://doi.org/10.18632/oncotarget.22606

Tong Xu, Jiezhen Lu,  and Hanxiang An
109079-109093
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Shikonin induces ROS-based mitochondria-mediated apoptosis in colon cancer

Shikonin induces ROS-based mitochondria-mediated apoptosis in colon cancer

https://doi.org/10.18632/oncotarget.22618

Wenquan Liang, Jianxin Cui, Kecheng Zhang, Hongqing Xi, Aizhen Cai, Jiyang Li, Yunhe Gao, Chong Hu, Yi Liu, Yixun Lu, Ning Wang, Xiaosong Wu, Bo Wei,  and Lin Chen
109094-109106
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Investigation of TCF7L2, LEP and LEPR polymorphisms with esophageal squamous cell carcinomas

Investigation of TCF7L2, LEP and LEPR polymorphisms with esophageal squamous cell carcinomas

https://doi.org/10.18632/oncotarget.22619

Hao Qiu, Xunting Lin, Weifeng Tang, Chao Liu, Yu Chen, Hao Ding, Mingqiang Kang,  and Shuchen Chen
109107-109119
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Pyruvate kinase M2 phosphorylates H2AX and promotes genomic instability in human tumor cells

Pyruvate kinase M2 phosphorylates H2AX and promotes genomic instability in human tumor cells

https://doi.org/10.18632/oncotarget.22621

Li Xia, Kang Qin, Xin-Ran Wang, Xiao-Ling Wang, Ai-Wu Zhou, Guo-Qiang Chen,  and Ying Lu
109120-109134
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RA and ω-3 PUFA co-treatment activates autophagy in cancer cells

RA and ω-3 PUFA co-treatment activates autophagy in cancer cells

https://doi.org/10.18632/oncotarget.22629

Shenglong Zhu, Guangxiao Lin, Ci Song, Yikuan Wu, Ninghan Feng, Wei Chen, Zhao He,  and Yong Q. Chen
109135-109150
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Targeting of CD122 enhances antitumor immunity by altering the tumor immune environment

Targeting of CD122 enhances antitumor immunity by altering the tumor immune environment

https://doi.org/10.18632/oncotarget.22642

Daniel O. Villarreal, Michael J. Allegrezza, Melissa A. Smith, Diana Chin, Leopoldo L. Luistro,  and Linda A. Snyder
109151-109160
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Interleukin-22 participates in the inflammatory process of vitiligo

Interleukin-22 participates in the inflammatory process of vitiligo

https://doi.org/10.18632/oncotarget.22644

Jinjin Dong, Xiaohong An, Hui Zhong, Yichuan Wang, Jing Shang,  and Jia Zhou
109161-109174
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Histopathological, molecular, clinical and radiological characterization of rosette-forming glioneuronal tumor in the central nervous system

Histopathological, molecular, clinical and radiological characterization of rosette-forming glioneuronal tumor in the central nervous system

https://doi.org/10.18632/oncotarget.22646

Chenlong Yang, Jingyi Fang, Guang Li, Shaowu Li, Tingting Ha, Jiangfei Wang, Bao Yang, Jun Yang,  and Yulun Xu
109175-109190
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Mild hypothermia modulates the expression of nestin and caspase-3 in the sub-granular zone and improves neurological outcomes in rats with ischemic stroke

Mild hypothermia modulates the expression of nestin and caspase-3 in the sub-granular zone and improves neurological outcomes in rats with ischemic stroke

https://doi.org/10.18632/oncotarget.22647

Dan Yu, Xueying Wang, Feng Zhou, Liang Wang, Guoshuai Yang, Wei Zhong, Ying Li, Zhiping Zhou, Aiyue Wang,  and Yanhui Zhou
109191-109200
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Inhibition of hepatocellular carcinoma growth by blockade of glycosphingolipid synthesis

Inhibition of hepatocellular carcinoma growth by blockade of glycosphingolipid synthesis

https://doi.org/10.18632/oncotarget.22648

Richard Jennemann, Giuseppina Federico, Daniel Mathow, Mariona Rabionet, Francesca Rampoldi, Zoran V. Popovic, Martina Volz, Thomas Hielscher, Roger Sandhoff,  and Hermann-Josef Gröne
109201-109216
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Tanshinone IIA inhibits angiogenesis in human endothelial progenitor cells in vitro and in vivo

Tanshinone IIA inhibits angiogenesis in human endothelial progenitor cells in vitro and in vivo

https://doi.org/10.18632/oncotarget.22649

Hsiang-Ping Lee, Yueh-Ching Liu, Po-Chun Chen, Huai-Ching Tai, Te-Mao Li, Yi-Chin Fong, Chih-Shiang Chang, Min-Huan Wu, Li-Pin Chiu, Chia-Jung Wang, Yi-Hsuan Chen, Yih-Jer Wu, Chih-Hsin Tang,  and Shih-Wei Wang
109217-109227
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Intratumoral heterogeneity and TERT promoter mutations in progressive/higher-grade meningiomas

Intratumoral heterogeneity and TERT promoter mutations in progressive/higher-grade meningiomas

https://doi.org/10.18632/oncotarget.22650

Tareq A. Juratli, Christian Thiede, Mara V.A. Koerner, Shilpa S. Tummala, Dirk Daubner, Ganesh M. Shankar, Erik A. Williams, Maria Martinez-Lage, Silke Soucek, Katja Robel, Tristan Penson, Mechthild Krause, Steffen Appold, Matthias Meinhardt, Thomas Pinzer, Julie J. Miller, Dietmar Krex, Heather A. Ely, Ian M. Silverman, Jason Christiansen, Gabriele Schackert, Hiroaki Wakimoto, Matthias Kirsch, Priscilla K. Brastianos,  and Daniel P. Cahill
109228-109237
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Serum amyloid a induces M2b-like macrophage polarization during liver inflammation

Serum amyloid a induces M2b-like macrophage polarization during liver inflammation

https://doi.org/10.18632/oncotarget.22652

Yibin Wang, Haijun Huang, Renhua Sun, Bingyu Chen, Fang Han, Qian Li, Yin Ni, Xi Li, Jingquan Liu, Xiaozhou Mou,  and Yuexing Tu
109238-109246
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Overexpression of SCAMP3 is an indicator of poor prognosis in hepatocellular carcinoma

Overexpression of SCAMP3 is an indicator of poor prognosis in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.22665

Xinyuan Zhang, Jie Sheng, Yuhong Zhang, Yu Tian, Jie Zhu, Nan Luo, Congshu Xiao,  and Rongkuan Li
109247-109257
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Induction of renal artery hyperresponsiveness by alpha1-adrenoceptor in hepatorenal syndrome

Induction of renal artery hyperresponsiveness by alpha1-adrenoceptor in hepatorenal syndrome

https://doi.org/10.18632/oncotarget.22668

Xiaogang Zhang, Xinsen Xu, Yina Jiang, Jianyu He, Wenjing Wang, Wei Li, Xufeng Zhang,  and Yi Lv
109258-109270
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Androgen enhances the activity of ETS-1 and promotes the proliferation of HCC cells

Androgen enhances the activity of ETS-1 and promotes the proliferation of HCC cells

https://doi.org/10.18632/oncotarget.22669

Hui Ren, Bo Ren, Jiabin Zhang, Xiaofeng Zhang, Lixin Li, Lingzhan Meng, Zhijie Li, Jia Li, Yinjie Gao,  and Xuemei Ma
109271-109288
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APRIL promotes non-small cell lung cancer growth and metastasis by targeting ERK1/2 signaling

APRIL promotes non-small cell lung cancer growth and metastasis by targeting ERK1/2 signaling

https://doi.org/10.18632/oncotarget.22672

Hengli Dou, Zhaohua Yan, Meng Zhang,  and Xiaoxin Xu
109289-109300
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Ascl2 activation by YAP1/KLF5 ensures the self-renewability of colon cancer progenitor cells

Ascl2 activation by YAP1/KLF5 ensures the self-renewability of colon cancer progenitor cells

https://doi.org/10.18632/oncotarget.22673

Xiaolong Wei, Jun Ye, Yangyang Shang, Haoyuan Chen, Shanxi Liu, Li Liu,  and Rongquan Wang
109301-109318
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Inhibitor repurposing reveals ALK, LTK, FGFR, RET and TRK kinases as the targets of AZD1480

Inhibitor repurposing reveals ALK, LTK, FGFR, RET and TRK kinases as the targets of AZD1480

https://doi.org/10.18632/oncotarget.22674

Iva Gudernova, Lukas Balek, Miroslav Varecha, Jana Fialova Kucerova, Michaela Kunova Bosakova, Bohumil Fafilek, Veronika Palusova, Stjepan Uldrijan, Lukas Trantirek,  and Pavel Krejci
109319-109331
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Association between SOD1, CAT, GSHPX1 polymorphisms and the risk of inflammatory bowel disease in the Polish population

Association between SOD1, CAT, GSHPX1 polymorphisms and the risk of inflammatory bowel disease in the Polish population

https://doi.org/10.18632/oncotarget.22675

Malgorzata Mrowicka, Jerzy Mrowicki, Michal Mik, Radoslaw Wojtczak, Lukasz Dziki, Adam Dziki,  and Ireneusz Majsterek
109332-109339
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The anti-cancer effects and mechanisms of Scutellaria barbata D. Don on CL1-5 lung cancer cells

The anti-cancer effects and mechanisms of Scutellaria barbata D. Don on CL1-5 lung cancer cells

https://doi.org/10.18632/oncotarget.22677

Chin-Chuan Chen, Chun-Pin Kao, Mei-Miao Chiu,  and Shu-Huei Wang
109340-109357
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Dysregulated connexin 43 in HER2-positive drug resistant breast cancer cells enhances proliferation and migration

Dysregulated connexin 43 in HER2-positive drug resistant breast cancer cells enhances proliferation and migration

https://doi.org/10.18632/oncotarget.22678

Elizabeth S. Yeh, Christina J. Williams, Carly Bess Williams, Ingrid V. Bonilla, Nancy Klauber-DeMore,  and Stephanie L. Phillips
109358-109369
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3D-structured illumination microscopy reveals clustered DNA double-strand break formation in widespread γH2AX foci after high LET heavy-ion particle radiation

3D-structured illumination microscopy reveals clustered DNA double-strand break formation in widespread γH2AX foci after high LET heavy-ion particle radiation

https://doi.org/10.18632/oncotarget.22679

Yoshihiko Hagiwara, Atsuko Niimi, Mayu Isono, Motohiro Yamauchi, Takaaki Yasuhara, Siripan Limsirichaikul, Takahiro Oike, Hiro Sato, Kathryn D. Held, Takashi Nakano,  and Atsushi Shibata
109370-109381
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

XRCC1 serves as a potential prognostic indicator for clear cell renal cell carcinoma and inhibits its invasion and metastasis through suppressing MMP-2 and MMP-9

XRCC1 serves as a potential prognostic indicator for clear cell renal cell carcinoma and inhibits its invasion and metastasis through suppressing MMP-2 and MMP-9

https://doi.org/10.18632/oncotarget.22680

Qing-Hua Liu, You Wang, Hong-Mei Yong, Ping-Fu Hou, Jie Pan, Jin Bai,  and Jun-Nian Zheng
109382-109392
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Detection of HPV related oropharyngeal cancer in oral rinse specimens

Detection of HPV related oropharyngeal cancer in oral rinse specimens

https://doi.org/10.18632/oncotarget.22682

Matthew Rosenthal, Bin Huang, Nora Katabi, Jocelyn Migliacci, Robert Bryant, Samuel Kaplan, Timothy Blackwell, Snehal Patel, Liying Yang, Zhiheng Pei, Yi-Wei Tang,  and Ian Ganly
109393-109401
Abstract  |  PDF  |  HTML  |  Order a Reprint

T-cell responses to KSHV infection: a systematic approach

T-cell responses to KSHV infection: a systematic approach

https://doi.org/10.18632/oncotarget.22683

Romin Roshan, Nazzarena Labo, Matthew Trivett, Wendell Miley, Vickie Marshall, Lori Coren, Elena M. Cornejo Castro, Hannah Perez, Benjamin Holdridge, Eliza Davis, Rodrigo Matus-Nicodemos, Victor I. Ayala, Raymond Sowder II, Kathleen M. Wyvill, Karen Aleman, Christine Fennessey, Jeffrey Lifson, Mark N. Polizzotto, Daniel Douek, Brandon Keele, Thomas S. Uldrick, Robert Yarchoan, Claes Ohlen, David Ott,  and Denise Whitby
109402-109416
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Estrogen receptor signaling mediates leptin-induced growth of breast cancer cells via autophagy induction

Estrogen receptor signaling mediates leptin-induced growth of breast cancer cells via autophagy induction

https://doi.org/10.18632/oncotarget.22684

Pawan Kumar Raut, Dong Young Choi, Sang Hyun Kim, Jin Tae Hong, Taeg Kyu Kwon, Jee Heon Jeong,  and Pil-Hoon Park
109417-109435
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Systematic assessment of cervical cancer initiation and progression uncovers genetic panels for deep learning-based early diagnosis and proposes novel diagnostic and prognostic biomarkers

Systematic assessment of cervical cancer initiation and progression uncovers genetic panels for deep learning-based early diagnosis and proposes novel diagnostic and prognostic biomarkers

https://doi.org/10.18632/oncotarget.22689

Nguyen Phuoc Long, Kyung Hee Jung, Sang Jun Yoon, Nguyen Hoang Anh, Tran Diem Nghi, Yun Pyo Kang, Hong Hua Yan, Jung Eun Min, Soon-Sun Hong,  and Sung Won Kwon
109436-109456
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Copy number variations in atypical fibroxanthomas and pleomorphic dermal sarcomas

Copy number variations in atypical fibroxanthomas and pleomorphic dermal sarcomas

https://doi.org/10.18632/oncotarget.22691

Doris Helbig, Alexander Quaas, Cornelia Mauch, Sabine Merkelbach-Bruse, Reinhard Büttner, Michael Emberger, Marion Wobser, Vanessa Rüsseler, Katharina Pütz, Elke Binot, Jan Rehker, Jan Budczies,  and Michaela Angelika Ihle
109457-109467
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Elevated red blood cell distribution width predicts poor prognosis in hilar cholangiocarcinoma

Elevated red blood cell distribution width predicts poor prognosis in hilar cholangiocarcinoma

https://doi.org/10.18632/oncotarget.22694

Bei Li, Zhen You, Xian-Ze Xiong, Yong Zhou, Si-Jia Wu, Rong-Xing Zhou, Jiong Lu,  and Nan-Sheng Cheng
109468-109477
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Acute nutritional stress during pregnancy affects placental efficiency, fetal growth and adult glucose homeostasis

Acute nutritional stress during pregnancy affects placental efficiency, fetal growth and adult glucose homeostasis

https://doi.org/10.18632/oncotarget.22695

Sajida Malik, Alan Diot, Karl Morten, Eszter Dombi, Manu Vatish, C.A. Richard Boyd,  and Joanna Poulton
109478-109486
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Notoginsenoside R7 suppresses cervical cancer via PI3K/PTEN/Akt/mTOR signaling

Notoginsenoside R7 suppresses cervical cancer via PI3K/PTEN/Akt/mTOR signaling

https://doi.org/10.18632/oncotarget.22721

Li Li, Jin-Xia Sun, Xiao-Qi Wang, Xiao-Kai Liu, Xian-Xiong Chen, Bo Zhang, Zhen-Dan He, Dong-Zhou Liu, Li-Xin Chen, Li-Wei Wang,  and Zhong Huang
109487-109496
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Associations of plasma hepcidin with mortality risk in patients with coronary artery disease

Associations of plasma hepcidin with mortality risk in patients with coronary artery disease

https://doi.org/10.18632/oncotarget.22722

Xinrui Li, Ding Ding, Yuan Zhang, Dongfang Su, Min Wang, Xuechen Chen, Yan Yang, Changjiang Hong, Gang Hu,  and Wenhua Ling
109497-109508
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Long non-coding RNA HOXA11-AS promotes the proliferation HCC cells by epigenetically silencing DUSP5

Long non-coding RNA HOXA11-AS promotes the proliferation HCC cells by epigenetically silencing DUSP5

https://doi.org/10.18632/oncotarget.22723

Bin Liu, Jing Li, Xiaoling Liu, Min Zheng, Ye Yang, Qian Lyu,  and Li Jin
109509-109521
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Optimizing prognosis-related key miRNA-target interactions responsible for cancer metastasis

Optimizing prognosis-related key miRNA-target interactions responsible for cancer metastasis

https://doi.org/10.18632/oncotarget.22724

Hongying Zhao, Huating Yuan, Jing Hu, Chaohan Xu, Gaoming Liao, Wenkang Yin, Liwen Xu, Li Wang, Xinxin Zhang, Aiai Shi, Jing Li,  and Yun Xiao
109522-109535
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A proteomic approach for the identification of biomarkers in endometrial cancer uterine aspirate

A proteomic approach for the identification of biomarkers in endometrial cancer uterine aspirate

https://doi.org/10.18632/oncotarget.22725

Blendi Ura, Lorenzo Monasta, Giorgio Arrigoni, Cinzia Franchin, Oriano Radillo, Isabel Peterlunger, Giuseppe Ricci,  and Federica Scrimin
109536-109545
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MiR-520f promotes cell aggressiveness by regulating fibroblast growth factor 16 in hepatocellular carcinoma

MiR-520f promotes cell aggressiveness by regulating fibroblast growth factor 16 in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.22726

Feng Feng Xu, Wen Feng Xie, Guo Qing Zha, Hong Wu Chen,  and Liang Deng
109546-109558
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Fluorescence-guided surgery for cancer patients: a proof of concept study on human xenografts in mice and spontaneous tumors in pets

Fluorescence-guided surgery for cancer patients: a proof of concept study on human xenografts in mice and spontaneous tumors in pets

https://doi.org/10.18632/oncotarget.22728

Eliane Mery, Muriel Golzio, Stephanie Guillermet, Didier Lanore, Augustin Le Naour, Benoît Thibault, Anne Françoise Tilkin-Mariamé, Elizabeth Bellard, Jean Pierre Delord, Denis Querleu, Gwenael Ferron,  and Bettina Couderc
109559-109574
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Neat1 in hematopoietic stem cells

Neat1 in hematopoietic stem cells

https://doi.org/10.18632/oncotarget.22729

Noam Fallik, Yael Bar-Lavan, Yariv Greenshpan, Oron Goldstein, Markus Grosch, Micha Drukker,  and Roi Gazit
109575-109586
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Proteomic approach toward determining the molecular background of pazopanib resistance in synovial sarcoma

Proteomic approach toward determining the molecular background of pazopanib resistance in synovial sarcoma

https://doi.org/10.18632/oncotarget.22730

Zhiwei Qiao, Kumiko Shiozawa,  and Tadashi Kondo
109587-109595
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TRIB2 contributes to cisplatin resistance in small cell lung cancer

TRIB2 contributes to cisplatin resistance in small cell lung cancer

https://doi.org/10.18632/oncotarget.22741

Yuanxin Liang, Dong Yu, Roman Perez-Soler, Jim Klostergaard,  and Yiyu Zou
109596-109608
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The synergistic antitumor effect of arsenic trioxide combined with cytotoxic T cells in pulmonary metastasis model of colon cancer

The synergistic antitumor effect of arsenic trioxide combined with cytotoxic T cells in pulmonary metastasis model of colon cancer

https://doi.org/10.18632/oncotarget.22757

Lei Wang, Wentao Liang, Na Peng, Xiang Hu, Yingxin Xu,  and Zhong Liu
109609-109618
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Experimental verification of a 3D in vivo dose monitoring system based on EPID

Experimental verification of a 3D in vivo dose monitoring system based on EPID

https://doi.org/10.18632/oncotarget.22758

Xiaoyong Wang, Lixin Chen, Conghua Xie, Dajiang Wang, Gaili Chen, Zhengming Fu,  and Hui Liu
109619-109631
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LRP6 promotes invasion and metastasis of colorectal cancer through cytoskeleton dynamics

LRP6 promotes invasion and metastasis of colorectal cancer through cytoskeleton dynamics

https://doi.org/10.18632/oncotarget.22759

Qian Yao, Yu An, Wei Hou, Ya-Nan Cao, Meng-Fei Yao, Ning-Ning Ma, Lin Hou, Hong Zhang, Hai-Jing Liu,  and Bo Zhang
109632-109645
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Tumor gene expression data classification via sample expansion-based deep learning

Tumor gene expression data classification via sample expansion-based deep learning

https://doi.org/10.18632/oncotarget.22762

Jian Liu, Xuesong Wang, Yuhu Cheng,  and Lin Zhang
109646-109660
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Notch signaling negatively regulates BMP9-induced osteogenic differentiation of mesenchymal progenitor cells by inhibiting JunB expression

Notch signaling negatively regulates BMP9-induced osteogenic differentiation of mesenchymal progenitor cells by inhibiting JunB expression

https://doi.org/10.18632/oncotarget.22763

Nan Wang, Wei Liu, Tao Tan, Chao-Qun Dong, Duan-Yang Lin, Jun Zhao, Chang Yu,  and Xiao-Ji Luo
109661-109674
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Coregulator profiling of the glucocorticoid receptor in lymphoid malignancies

Coregulator profiling of the glucocorticoid receptor in lymphoid malignancies

https://doi.org/10.18632/oncotarget.22764

Dorien Clarisse, Jonathan Thommis, Karlien Van Wesemael, René Houtman, Dariusz Ratman, Jan Tavernier, Fritz Offner, Ilse Beck,  and Karolien De Bosscher
109675-109691
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Progranulin derived engineered protein Atsttrin suppresses TNF-α-mediated inflammation in intervertebral disc degenerative disease

Progranulin derived engineered protein Atsttrin suppresses TNF-α-mediated inflammation in intervertebral disc degenerative disease

https://doi.org/10.18632/oncotarget.22766

Hong Ding, Jianlu Wei, Yunpeng Zhao, Yi Liu, Lian Liu,  and Lei Cheng
109692-109702
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Meta-Analysis

Comparing the ORBIT and HAS-BLED bleeding risk scores in anticoagulated atrial fibrillation patients: a systematic review and meta-analysis

Comparing the ORBIT and HAS-BLED bleeding risk scores in anticoagulated atrial fibrillation patients: a systematic review and meta-analysis

https://doi.org/10.18632/oncotarget.19858

Cen Wang, Ye Yu, Wengen Zhu, Jianhua Yu, Gregory Y.H. Lip,  and Kui Hong
109703-109711
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Impact of epidermal growth factor receptor sensitizing mutations on outcomes of patients with non-small cell lung cancer treated with definitive thoracic radiation therapy: a systematic review and meta-analysis

Impact of epidermal growth factor receptor sensitizing mutations on outcomes of patients with non-small cell lung cancer treated with definitive thoracic radiation therapy: a systematic review and meta-analysis

https://doi.org/10.18632/oncotarget.21019

Yu Yang Soon, Balamurugan Vellayappan, Jeremy Chee Seong Tey, Cheng Nang Leong, Wee Yao Koh,  and Ivan Weng Keong Tham
109712-109722
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Efficacy of sorafenib in patients with hepatocellular carcinoma after resection: a meta-analysis

Efficacy of sorafenib in patients with hepatocellular carcinoma after resection: a meta-analysis

https://doi.org/10.18632/oncotarget.21299

Jin Shang, Shanling Xu, Jiaxing Zhang, Xuting Ran, Lang Bai,  and Hong Tang
109723-109731
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Clinicopathological significance of CHFR methylation in non-small cell lung cancer: a systematic review and meta-analysis

Clinicopathological significance of CHFR methylation in non-small cell lung cancer: a systematic review and meta-analysis

https://doi.org/10.18632/oncotarget.21962

Chen Wang, Wenxia Ma, Rong Wei, Xiaoqin Zhang, Ningning Shen, Lifang Shang, Li E, Ying Wang, Lifang Gao, Xin Li, Bin Wang, Yaping Zhang,  and Aiping Du
109732-109739
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Systematic review and meta-analysis of the prognostic value of CXCR2 in solid tumor patients

Systematic review and meta-analysis of the prognostic value of CXCR2 in solid tumor patients

https://doi.org/10.18632/oncotarget.22285

Yong Yang, Baoyang Luo, Yong An, Han Sun, Huihua Cai,  and Donglin Sun
109740-109751
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Clinical Research Papers

Serum Galectin-3 level, not Galectin-1, is associated with the clinical feature and outcome in patients with acute ischemic stroke

Serum Galectin-3 level, not Galectin-1, is associated with the clinical feature and outcome in patients with acute ischemic stroke

https://doi.org/10.18632/oncotarget.18211

Han Dong, Zhi-Hao Wang, Na Zhang, Si-Da Liu, Jian-Jun Zhao,  and Song-Yan Liu
109752-109761
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Predictive value of post-procedural early (within 24 h) increase in cystatin C for contrast-induced acute kidney injury and mortality following coronary angiography or intervention

Predictive value of post-procedural early (within 24 h) increase in cystatin C for contrast-induced acute kidney injury and mortality following coronary angiography or intervention

https://doi.org/10.18632/oncotarget.19034

Yong Liu, Kai-Hong Chen, Shi-Qun Chen, Li-Ling Chen, Chong-Yang Duan, Kun Wang, Xiao-Sheng Guo, Hua-Long Li, Wei-Jie Bei, Kai-Yan Lin, Ping-Yan Chen, Ying Xian, Ning Tan, Ying-Ling Zhou, Qing-Shan Geng,  and Ji-Yan Chen
109762-109771
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Prognostic nomogram for acute-on-chronic hepatitis B liver failure

Prognostic nomogram for acute-on-chronic hepatitis B liver failure

https://doi.org/10.18632/oncotarget.21012

Su Lin, Juan Chen, Mingfang Wang, Lifen Han, Haoyang Zhang, Jing Dong, Dawu Zeng, Jiaji Jiang,  and Yueyong Zhu
109772-109782
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Predicting clinically significant prostate cancer based on pre-operative patient profile and serum biomarkers

Predicting clinically significant prostate cancer based on pre-operative patient profile and serum biomarkers

https://doi.org/10.18632/oncotarget.21297

Izak Faiena, Sinae Kim, Nicholas Farber, Young Suk Kwon, Brian Shinder, Neal Patel, Amirali H. Salmasi, Thomas Jang, Eric A. Singer, Wun-Jae Kim,  and Isaac Y. Kim
109783-109790
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Microwave ablation versus radiofrequency ablation for the treatment of pulmonary tumors

Microwave ablation versus radiofrequency ablation for the treatment of pulmonary tumors

https://doi.org/10.18632/oncotarget.22308

Feng Shi, Guangxiao Li, Zejian Zhou, Rongde Xu, Weike Li, Wenhang Zhuang, Zide Chen,  and Xiaoming Chen
109791-109798
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Reviews

Nanoparticles and female reproductive system: how do nanoparticles affect oogenesis and embryonic development

Nanoparticles and female reproductive system: how do nanoparticles affect oogenesis and embryonic development

https://doi.org/10.18632/oncotarget.19087

Cong-Cong Hou,  and Jun-Quan Zhu
109799-109817
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Molecular characterization of circulating tumor cells in lung cancer: moving beyond enumeration

Molecular characterization of circulating tumor cells in lung cancer: moving beyond enumeration

https://doi.org/10.18632/oncotarget.22651

Lei Wang, Coraline Dumenil, Catherine Julié, Violaine Giraud, Jennifer Dumoulin, Sylvie Labrune, Thierry Chinet, Jean-François Emile, Biao He,  and Etienne Giroux Leprieur
109818-109835
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Case Reports

Tyrosine kinase inhibitor sensitive PDGFRΑ mutations in GIST: Two cases and review of the literature

Tyrosine kinase inhibitor sensitive PDGFRΑ mutations in GIST: Two cases and review of the literature

https://doi.org/10.18632/oncotarget.22663

Pieter A. Boonstra, Jourik A. Gietema, Albert J.H. Suurmeijer, Matthew R. Groves, Fernando de Assis Batista, Ed Schuuring,  and Anna K.L. Reyners
109836-109847
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Research Papers

While reinforcing cell cycle arrest, rapamycin and Torins suppress senescence in UVA-irradiated fibroblasts

While reinforcing cell cycle arrest, rapamycin and Torins suppress senescence in UVA-irradiated fibroblasts

https://doi.org/10.18632/oncotarget.17827

Olga V. Leontieva,  and Mikhail V. Blagosklonny
109848-109856
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