Oncotarget

Vol 8, No 62

December 1, 2017

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About The Cover

The cover for issue 62 of Oncotarget features Supplementary Figure 4, "Histopathological analysis of liver and lung of mice injected with PBMCs, PBMCs and nTreg cells expanded in the presence of rapamycin alone or rapamycin (R) associated with vorinostat and azacytidin (RAV). Broken line circles surround lymphocytic infiltrates," from Miyara, et al.

Table of Contents

Editorial

Targeting macrophages to treat intracranial aneurysm

Targeting macrophages to treat intracranial aneurysm

https://doi.org/10.18632/oncotarget.21368

Tomohiro Aoki, Rie Yamamoto,  and Shuh Narumiya
104704-104705
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Research Papers: Gerotarget (Focus on Aging)

Weight loss in the healthy elderly might be a non-cognitive sign of preclinical Alzheimer’s disease

Weight loss in the healthy elderly might be a non-cognitive sign of preclinical Alzheimer’s disease

https://doi.org/10.18632/oncotarget.22218

Amanda Jimenez, Jordi Pegueroles, María Carmona-Iragui, Eduard Vilaplana, Victor Montal, Daniel Alcolea, Laura Videla, Ignacio Illán-Gala, Adriana Pané, Anna Casajoana, Olivia Belbin, Jordi Clarimón, Violeta Moizé, Josep Vidal, Alberto Lleó, Juan Fortea, Rafael Blesa,  and The Alzheimer’s Disease Neuroimaging Initiative
104706-104716
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Research Papers

Rab coupling protein mediated endosomal recycling of N-cadherin influences cell motility

Rab coupling protein mediated endosomal recycling of N-cadherin influences cell motility

https://doi.org/10.18632/oncotarget.10513

Andrew J. Lindsay,  and Mary W. McCaffrey
104717-104732
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Combination of IL-2, rapamycin, DNA methyltransferase and histone deacetylase inhibitors for the expansion of human regulatory T cells

Combination of IL-2, rapamycin, DNA methyltransferase and histone deacetylase inhibitors for the expansion of human regulatory T cells

https://doi.org/10.18632/oncotarget.10914

Makoto Miyara, Driss Chader, Aude Burlion, Jérémie Goldstein, Delphine Sterlin, Françoise Norol, Hélène Trebeden-Nègre, Laetitia Claër, Shimon Sakaguchi, Gilles Marodon, Zahir Amoura,  and Guy Gorochov
104733-104744
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Discovery and evaluation of triple inhibitors of VEGFR-2, TIE-2 and EphB4 as anti-angiogenic and anti-cancer agents

Discovery and evaluation of triple inhibitors of VEGFR-2, TIE-2 and EphB4 as anti-angiogenic and anti-cancer agents

https://doi.org/10.18632/oncotarget.20065

Lin Zhang, Yuanyuan Shan, Xingyue Ji, Mengyuan Zhu, Chuansheng Li, Ying Sun, Ru Si, Xiaoyan Pan, Jinfeng Wang, Weina Ma, Bingling Dai, Binghe Wang,  and Jie Zhang
104745-104760
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Molecular analyses of prostate tumors for diagnosis of malignancy on fine-needle aspiration biopsies

Molecular analyses of prostate tumors for diagnosis of malignancy on fine-needle aspiration biopsies

https://doi.org/10.18632/oncotarget.22289

Menglin Shan, Qianlin Xia, Dong Yan, Yanjun Zhu, Xuan Zhang, Guihong Zhang, Jianming Guo, Jun Hou, Weiping Chen, Tongyu Zhu, Xiaoyan Zhang, Jianqing Xu, Jin Wang, Tao Ding,  and Jianghua Zheng
104761-104771
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Tumor-suppressive effect of S-adenosylmethionine supplementation in a murine model of inflammation-mediated hepatocarcinogenesis is dependent on treatment longevity

Tumor-suppressive effect of S-adenosylmethionine supplementation in a murine model of inflammation-mediated hepatocarcinogenesis is dependent on treatment longevity

https://doi.org/10.18632/oncotarget.18300

Evgeniy Stoyanov, Lina Mizrahi, Devorah Olam, Temima Schnitzer-Perlman, Eithan Galun,  and Daniel S. Goldenberg
104772-104784
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Clinicopathological features and prognosis of malignant peripheral nerve sheath tumor: a retrospective study of 159 cases from 1999 to 2016

Clinicopathological features and prognosis of malignant peripheral nerve sheath tumor: a retrospective study of 159 cases from 1999 to 2016

https://doi.org/10.18632/oncotarget.18975

Zhennan Yuan, Libin Xu, Zhenguo Zhao, Songfeng Xu, Xinxin Zhang, Ting Liu, Shuguang Zhang,  and Shengji Yu
104785-104795
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mRNA expression profiles obtained from microdissected pancreatic cancer cells can predict patient survival

mRNA expression profiles obtained from microdissected pancreatic cancer cells can predict patient survival

https://doi.org/10.18632/oncotarget.20076

Ana-Barbara García-García, M. Carmen Gómez-Mateo, Rebeca Hilario, Pilar Rentero-Garrido, Alvaro Martínez-Domenech, Veronica Gonzalez-Albert, Andres Cervantes, Pablo Marín-Garcia, Felipe Javier Chaves, Antonio Ferrández-Izquierdo,  and Luis Sabater
104796-104805
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Depression and its impact on health-related quality of life among Chinese inpatients with lung cancer

Depression and its impact on health-related quality of life among Chinese inpatients with lung cancer

https://doi.org/10.18632/oncotarget.21001

Wen Gu, Yan-Min Xu, Jun-Hong Zhu,  and Bao-Liang Zhong
104806-104812
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Lamin B2 binding to minichromosome maintenance complex component 7 promotes non-small cell lung carcinogenesis

Lamin B2 binding to minichromosome maintenance complex component 7 promotes non-small cell lung carcinogenesis

https://doi.org/10.18632/oncotarget.20338

Yinan Ma, Liangru Fei, Meiyu Zhang, Wenzhu Zhang, Xiaofang Liu, Congcong Wang, Yuan Luo, Haiyan Zhang,  and Yuchen Han
104813-104830
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Identification of novel gene expression signature in lung adenocarcinoma by using next-generation sequencing data and bioinformatics analysis

Identification of novel gene expression signature in lung adenocarcinoma by using next-generation sequencing data and bioinformatics analysis

https://doi.org/10.18632/oncotarget.21022

Ya-Ling Hsu, Jen-Yu Hung, Yen-Lung Lee, Feng-Wei Chen, Kuo-Feng Chang, Wei-An Chang, Ying-Ming Tsai, Inn-Wen Chong,  and Po-Lin Kuo
104831-104854
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Doxycycline inhibits breast cancer EMT and metastasis through PAR-1/NF-κB/miR-17/E-cadherin pathway

Doxycycline inhibits breast cancer EMT and metastasis through PAR-1/NF-κB/miR-17/E-cadherin pathway

https://doi.org/10.18632/oncotarget.20418

Weilong Zhong, Shuang Chen, Yuan Qin, Heng Zhang, Hongzhi Wang, Jing Meng, Longcong Huai, Qiang Zhang, Tingting Yin, Yueyang Lei, Jingxia Han, Lingfei He, Bo Sun, Huijuan Liu, Yanrong Liu, Honggang Zhou, Tao Sun,  and Cheng Yang
104855-104866
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MicroRNA-200a activates Nrf2 signaling to protect osteoblasts from dexamethasone

MicroRNA-200a activates Nrf2 signaling to protect osteoblasts from dexamethasone

https://doi.org/10.18632/oncotarget.20452

Sai Zhao, Li Mao, Shou-Guo Wang, Feng-Li Chen, Feng Ji,  and Hao-Dong Fei
104867-104876
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Dietary polyphenols influence antimetabolite agents: methotrexate, 6-mercaptopurine and 5-fluorouracil in leukemia cell lines

Dietary polyphenols influence antimetabolite agents: methotrexate, 6-mercaptopurine and 5-fluorouracil in leukemia cell lines

https://doi.org/10.18632/oncotarget.20501

Amani Mahbub, Christine Le Maitre, Sarah Haywood-Small, Neil Cross,  and Nicola Jordan-Mahy
104877-104893
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A c-Jun N-terminal kinase inhibitor, JNK-IN-8, sensitizes triple negative breast cancer cells to lapatinib

A c-Jun N-terminal kinase inhibitor, JNK-IN-8, sensitizes triple negative breast cancer cells to lapatinib

https://doi.org/10.18632/oncotarget.20581

Nancy D. Ebelt, Tamer S. Kaoud, Ramakrishna Edupuganti, Sabrina Van Ravenstein, Kevin N. Dalby,  and Carla L. Van
104894-104912
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A primary tumor gene expression signature identifies a crucial role played by tumor stroma myofibroblasts in lymph node involvement in oral squamous cell carcinoma

A primary tumor gene expression signature identifies a crucial role played by tumor stroma myofibroblasts in lymph node involvement in oral squamous cell carcinoma

https://doi.org/10.18632/oncotarget.20645

Gianluigi Mazzoccoli, Stefano Castellana, Massimo Carella, Orazio Palumbo, Cristiana Tiberio, Caterina Fusilli, Daniele Capocefalo, Tommaso Biagini, Tommaso Mazza,  and Lorenzo Lo Muzio
104913-104927
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A CARP-1 functional mimetic loaded vitamin E-TPGS micellar nano-formulation for inhibition of renal cell carcinoma

A CARP-1 functional mimetic loaded vitamin E-TPGS micellar nano-formulation for inhibition of renal cell carcinoma

https://doi.org/10.18632/oncotarget.20650

Vino T. Cheriyan, Hashem O. Alsaab, Sreeja Sekhar, Caitlin Stieber, Prashant Kesharwani, Samaresh Sau, Magesh Muthu, Lisa A. Polin, Edi Levi, Arun K. Iyer,  and Arun K. Rishi
104928-104945
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Soluble chemokine (C-X-C motif) ligand 16 (CXCL16) in urine as a novel biomarker candidate to identify high grade and muscle invasive urothelial carcinomas

Soluble chemokine (C-X-C motif) ligand 16 (CXCL16) in urine as a novel biomarker candidate to identify high grade and muscle invasive urothelial carcinomas

https://doi.org/10.18632/oncotarget.20737

Kerstin Lang, Nadine Bonberg, Sibylle Robens, Thomas Behrens, Jan Hovanec, Thomas Deix, Katharina Braun, Florian Roghmann, Joachim Noldus, Volker Harth, Karl-Heinz Jöckel, Raimund Erbel, Yu Chun Tam, Andrea Tannapfel, Heiko Udo Käfferlein,  and Thomas Brüning
104946-104959
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The protective value of miR-204-5p for prognosis and its potential gene network in various malignancies: a comprehensive exploration based on RNA-seq high-throughput data and bioinformatics

The protective value of miR-204-5p for prognosis and its potential gene network in various malignancies: a comprehensive exploration based on RNA-seq high-throughput data and bioinformatics

https://doi.org/10.18632/oncotarget.21950

Zhi-Hua Ye, Dong-Yue Wen, Xiao-Yong Cai, Liang Liang, Pei-Rong Wu, Hui Qin, Hong Yang, Yun He,  and Gang Chen
104960-104980
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Parity improves anti-tumor immunity in breast cancer patients

Parity improves anti-tumor immunity in breast cancer patients

https://doi.org/10.18632/oncotarget.20756

Anna-Lena Krause, Florian Schuetz, Marc Boudewijns, Maria Pritsch, Markus Wallwiener, Michael Golatta, Joachim Rom, Joerg Heil, Christof Sohn, Andreas Schneeweiss, Philipp Beckhove,  and Christoph Domschke
104981-104991
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Effects of trimetazidine on periprocedural microRNA-21 expression by CD4+ T lymphocytes in patients with unstable angina pectoris

Effects of trimetazidine on periprocedural microRNA-21 expression by CD4+ T lymphocytes in patients with unstable angina pectoris

https://doi.org/10.18632/oncotarget.20975

Qiang Su, Lang Li, Jinmin Zhao, Yuhan Sun,  and Huafeng Yang
104992-104999
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Four-month course of adjuvant dabrafenib in patients with surgically resected stage IIIC melanoma characterized by a BRAFV600E/K mutation

Four-month course of adjuvant dabrafenib in patients with surgically resected stage IIIC melanoma characterized by a BRAFV600E/K mutation

https://doi.org/10.18632/oncotarget.21072

Parisa Momtaz, James J. Harding, Charlotte Ariyan, Daniel G. Coit, Taha Merghoub, Billel Gasmi, Daoqi You, Agnes Viale, Katherine S. Panageas, Aliaksandra Samoila, Michael A. Postow, Jedd D. Wolchok,  and Paul B. Chapman
105000-105010
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Relationship of tumor size with pathological and prognostic factors for hilar cholangiocarcinoma

Relationship of tumor size with pathological and prognostic factors for hilar cholangiocarcinoma

https://doi.org/10.18632/oncotarget.22054

Hai-Jie Hu, Rong-Xing Zhou, Anuj Shrestha, Yong-Qiong Tan, Wen-Jie Ma, Qin Yang, Jiong Lu, Jun-Ke Wang, Yong Zhou,  and Fu-Yu Li
105011-105019
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Gene editing of the extra domain A positive fibronectin in various tumors, amplified the effects of CRISPR/Cas system on the inhibition of tumor progression

Gene editing of the extra domain A positive fibronectin in various tumors, amplified the effects of CRISPR/Cas system on the inhibition of tumor progression

https://doi.org/10.18632/oncotarget.21136

Wan-Qi Lv, Hai-Cheng Wang, Jing Peng, Yi-Xiang Wang, Jiu-Hui Jiang,  and Cui-Ying Li
105020-105036
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Associations between TNFSF4, TNFSF8 and TNFSF15 and Behçet's disease but not VKH syndrome in Han Chinese

Associations between TNFSF4, TNFSF8 and TNFSF15 and Behçet's disease but not VKH syndrome in Han Chinese

https://doi.org/10.18632/oncotarget.22064

Yan Jiang, Ling Cheng, Xin Li, Wenke Zhou,  and Li Zhang
105037-105046
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Synergistic effect of farnesyl transferase inhibitor lonafarnib combined with chemotherapeutic agents against the growth of hepatocellular carcinoma cells

Synergistic effect of farnesyl transferase inhibitor lonafarnib combined with chemotherapeutic agents against the growth of hepatocellular carcinoma cells

https://doi.org/10.18632/oncotarget.22086

Jialiang Wang, Yifan Lian, Yurong Gu, Hongbo Wang, Lin Gu, Yanlin Huang, Liang Zhou,  and Yuehua Huang
105047-105060
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AIO LQ-0110: a randomized phase II trial comparing oral doxycycline versus local administration of erythromycin as preemptive treatment strategies of panitumumab-mediated skin toxicity in patients with metastatic colorectal cancer

AIO LQ-0110: a randomized phase II trial comparing oral doxycycline versus local administration of erythromycin as preemptive treatment strategies of panitumumab-mediated skin toxicity in patients with metastatic colorectal cancer

https://doi.org/10.18632/oncotarget.21249

Melanie Kripp, Nicole Prasnikar, Ursula Vehling-Kaiser, Julia Quidde, Salah-Eddin Al-Batran, Alexander Stein, Kai Neben, Carla Verena Hannig, Hans Werner Tessen, Tanja Trarbach, Axel Hinke,  and Ralf-Dieter Hofheinz
105061-105071
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Targeted next generation sequencing in Chinese colorectal cancer patients guided anti-EGFR treatment and facilitated precision cancer medicine

Targeted next generation sequencing in Chinese colorectal cancer patients guided anti-EGFR treatment and facilitated precision cancer medicine

https://doi.org/10.18632/oncotarget.21349

Helei Hou, Dong Liu, Chuantao Zhang, Yanxia Jiang, Guifang Lu, Na Zhou, Xiaonan Yan, Xiaoping Zhang, Zhuokun Li, Hongmei Zhu, Zhaoyang Qian,  and Xiaochun Zhang
105072-105080
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Eyes absent gene (EYA1) is a pathogenic driver and a therapeutic target for melanoma

Eyes absent gene (EYA1) is a pathogenic driver and a therapeutic target for melanoma

https://doi.org/10.18632/oncotarget.21352

Joshua Jiawei Zhou, Yuanshen Huang, Xue Zhang, Yabin Cheng, Liren Tang,  and Xiaodong Ma
105081-105092
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Intrapleural targeted therapies (anti-VEGF and anti-EGFR) in the model of malignant pleural effusion

Intrapleural targeted therapies (anti-VEGF and anti-EGFR) in the model of malignant pleural effusion

https://doi.org/10.18632/oncotarget.21362

Milena Marques Pagliarelli Acencio, Juliana Puka, Vanessa Adélia Alvarenga, Vanessa Martins, Mariana Lombardi Peres de Carvalho, Evaldo Marchi, Vera Luiza Capelozzi,  and Lisete Ribeiro Teixeira
105093-105102
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Outcome of EGFR-mutated NSCLC patients with MET-driven resistance to EGFR tyrosine kinase inhibitors

Outcome of EGFR-mutated NSCLC patients with MET-driven resistance to EGFR tyrosine kinase inhibitors

https://doi.org/10.18632/oncotarget.21707

Simon Baldacci, Julien Mazieres, Pascale Tomasini, Nicolas Girard, Florian Guisier, Clarisse Audigier-Valette, Isabelle Monnet, Marie Wislez, Maurice Pérol, Pascal Dô, Eric Dansin, Charlotte Leduc, Etienne Giroux Leprieur, Denis Moro-Sibilot, David Tulasne, Zoulika Kherrouche, Julien Labreuche,  and Alexis B. Cortot
105103-105114
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Hepatitis B virus (HBV) X gene mutations and their association with liver disease progression in HBV-infected patients

Hepatitis B virus (HBV) X gene mutations and their association with liver disease progression in HBV-infected patients

https://doi.org/10.18632/oncotarget.22428

Ahmed A. Al-Qahtani, Mashael R. Al-Anazi, Nyla Nazir, Rohit Ghai, Ayman A. Abdo, Faisal M. Sanai, Waleed K. Al-Hamoudi, Khalid A. Alswat, Hamad I. Al-Ashgar, Mohammed Q. Khan, Ali Albenmousa, Damian Dela Cruz, Marie Fe F. Bohol,  and Mohammed N. Al-Ahdal
105115-105125
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Low density lipoprotein - rosiglitazone - chitosan-calcium alginate/nanoparticles inhibition of human tenon’s fibroblasts activation and proliferation

Low density lipoprotein - rosiglitazone - chitosan-calcium alginate/nanoparticles inhibition of human tenon’s fibroblasts activation and proliferation

https://doi.org/10.18632/oncotarget.21757

Yi Gong, Jia-Yang Yin, Bo-Ding Tong, Jie-Xi Zeng,  and Wei Xiong
105126-105136
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Molecular basis for the DNA damage induction and anticancer activity of asymmetrically substituted anthrapyridazone PDZ-7

Molecular basis for the DNA damage induction and anticancer activity of asymmetrically substituted anthrapyridazone PDZ-7

https://doi.org/10.18632/oncotarget.21806

Majus Misiak, Mateusz Heldt, Marlena Szeligowska, Stefania Mazzini, Leonardo Scaglioni, Grzegorz J. Grabe, Marcin Serocki, Jan Lica, Marta Switalska, Joanna Wietrzyk, Giovanni L. Beretta, Paola Perego, Dominik Zietkowski, Maciej Baginski, Edward Borowski,  and Andrzej Skladanowski
105137-105154
Abstract  |  PDF  |  HTML  |  Order a Reprint

GOLPH3: a novel biomarker that correlates with poor survival and resistance to chemotherapy in breast cancer

GOLPH3: a novel biomarker that correlates with poor survival and resistance to chemotherapy in breast cancer

https://doi.org/10.18632/oncotarget.21927

Shicong Tang, Hong Pan, Wei Wei, Huawei Yang, Jianlun Liu,  and Rirong Yang
105155-105169
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Roscovitine strongly enhances the effect of olaparib on radiosensitivity for HPV neg. but not for HPV pos. HNSCC cell lines

Roscovitine strongly enhances the effect of olaparib on radiosensitivity for HPV neg. but not for HPV pos. HNSCC cell lines

https://doi.org/10.18632/oncotarget.22005

Frank Ziemann, Steve Seltzsam, Kristin Dreffke, Stefanie Preising, Andrea Arenz, Florentine S.B. Subtil, Thorsten Rieckmann, Rita Engenhart-Cabillic, Ekkehard Dikomey,  and Andrea Wittig
105170-105183
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

High visceral fat percentage is associated with poor outcome in endometrial cancer

High visceral fat percentage is associated with poor outcome in endometrial cancer

https://doi.org/10.18632/oncotarget.21917

Karen Klepsland Mauland, Øyvin Eng, Sigmund Ytre-Hauge, Ingvild L. Tangen, Anna Berg, Helga B. Salvesen, D8;yvind O. Salvesen, Camilla Krakstad, Jone Trovik, Erling A. Hoivik, Henrica Maria Johanna Werner, Gunnar Mellgren,  and Ingfrid S. Haldorsen
105184-105195
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Coordinated downregulation of Spinophilin and the catalytic subunits of PP1, PPP1CA/B/C, contributes to a worse prognosis in lung cancer

Coordinated downregulation of Spinophilin and the catalytic subunits of PP1, PPP1CA/B/C, contributes to a worse prognosis in lung cancer

https://doi.org/10.18632/oncotarget.22111

Eva M. Verdugo-Sivianes, Lola Navas, Sonia Molina-Pinelo, Irene Ferrer, Alvaro Quintanal-Villalonga, Javier Peinado, Jose M. Garcia-Heredia, Blanca Felipe-Abrio, Sandra Muñoz-Galvan, Juan J. Marin, Luis Montuenga, Luis Paz-Ares,  and Amancio Carnero
105196-105210
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A population pharmacokinetic model for individualised dosage regimens of vancomycin in Chinese neonates and young infants

A population pharmacokinetic model for individualised dosage regimens of vancomycin in Chinese neonates and young infants

https://doi.org/10.18632/oncotarget.22114

Lin Song, Cui-Yao He, Nan-Ge Yin, Fang Liu, Yun-Tao Jia,  and Yao Liu
105211-105221
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Gene function analysis and underlying mechanism of esophagus cancer based on microarray gene expression profiling

Gene function analysis and underlying mechanism of esophagus cancer based on microarray gene expression profiling

https://doi.org/10.18632/oncotarget.22160

Ying Yue, Mengjia Song, Yamin Qiao, Pupu Li, Yiqiang Yuan, Jingyao Lian, Suying Wang,  and Yi Zhang
105222-105237
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

CTHRC1 activates pro-tumorigenic signaling pathways in hepatocellular carcinoma

CTHRC1 activates pro-tumorigenic signaling pathways in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.22164

Yunpeng Wang, Mijin Lee, Goungran Yu, Hua Lee, Xueji Han,  and Daeghon Kim
105238-105250
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Super enhancer associated RAI14 is a new potential biomarker in lung adenocarcinoma

Super enhancer associated RAI14 is a new potential biomarker in lung adenocarcinoma

https://doi.org/10.18632/oncotarget.22165

Chongze Yuan, Hong Hu, Muyu Kuang, Zongwei Chen, Xiaoting Tao, Shengjian Fang, Yihua Sun, Yawei Zhang,  and Haiquan Chen
105251-105261
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Retinol dehydrogenase-10 promotes development and progression of human glioma via the TWEAK-NF-κB axis

Retinol dehydrogenase-10 promotes development and progression of human glioma via the TWEAK-NF-κB axis

https://doi.org/10.18632/oncotarget.22166

Feng Guan, Liang Wang, Shuyu Hao, Zhen Wu, Jian Bai, Zhuang Kang, Quan Zhou, Hong Chang, Hui Yin, Da Li, Kaibin Tian, Junpeng Ma, Guijun Zhang,  and Junting Zhang
105262-105275
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SPC24 promotes osteosarcoma progression by increasing EGFR/MAPK signaling

SPC24 promotes osteosarcoma progression by increasing EGFR/MAPK signaling

https://doi.org/10.18632/oncotarget.22167

Jun Sheng, Mengchen Yin, Zhengwang Sun, Xia Kang, Da Liu, Kai Jiang, Jia Xu, Feixing Zhao, Qunfeng Guo,  and Wei Zheng
105276-105283
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Abnormally glycosylated MUC1 establishes a positive feedback circuit of inflammatory cytokines, mediated by NF-κB p65 and EzH2, in colitis-associated cancer

Abnormally glycosylated MUC1 establishes a positive feedback circuit of inflammatory cytokines, mediated by NF-κB p65 and EzH2, in colitis-associated cancer

https://doi.org/10.18632/oncotarget.22168

Sandra Cascio, Jacque L. Faylo, Joshua C. Sciurba, Jia Xue, Sarangarajan Ranganathan, Jason J. Lohmueller, Pamela L. Beatty,  and Olivera J. Finn
105284-105298
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Immunological landscape of consensus clusters in colorectal cancer

Immunological landscape of consensus clusters in colorectal cancer

https://doi.org/10.18632/oncotarget.22169

Pawel Karpinski, Joanna Rossowska,  and Maria Malgorzata Sasiadek
105299-105311
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Functional polymorphisms in NR3C1 are associated with gastric cancer risk in Chinese population

Functional polymorphisms in NR3C1 are associated with gastric cancer risk in Chinese population

https://doi.org/10.18632/oncotarget.22172

Yayun Gu, Bin Deng, Jing Kong, Caiwang Yan, Tongtong Huang, Jianshui Yang, Yan Wang, Tianpei Wang, Qi Qi, Guangfu Jin, Jiangbo Du, Yanbing Ding,  and Li Liu
105312-105319
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MicroRNA co-expression networks exhibit increased complexity in pancreatic ductal compared to Vater’s papilla adenocarcinoma

MicroRNA co-expression networks exhibit increased complexity in pancreatic ductal compared to Vater’s papilla adenocarcinoma

https://doi.org/10.18632/oncotarget.22184

Tommaso Mazza, Massimiliano Copetti, Daniele Capocefalo, Caterina Fusilli, Tommaso Biagini, Massimo Carella, Antonio De Bonis, Nicola Mastrodonato, Ada Piepoli, Valerio Pazienza, Evaristo Maiello, Fabio Francesco di Mola, Pierluigi di Sebastiano, Angelo Andriulli,  and Francesca Tavano
105320-105339
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Agrin para-secreted by PDGF-activated human hepatic stellate cells promotes hepatocarcinogenesis in vitro and in vivo

Agrin para-secreted by PDGF-activated human hepatic stellate cells promotes hepatocarcinogenesis in vitro and in vivo

https://doi.org/10.18632/oncotarget.22186

Xing Lv, Cheng Fang, Ruozhe Yin, Bowei Qiao, Runze Shang, Jianlin Wang, Wenjie Song, Yong He,  and Yong Chen
105340-105355
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Investigation of RIP140 and LCoR as independent markers for poor prognosis in cervical cancer

Investigation of RIP140 and LCoR as independent markers for poor prognosis in cervical cancer

https://doi.org/10.18632/oncotarget.22187

Aurelia Vattai, Vincent Cavailles, Sophie Sixou, Susanne Beyer, Christina Kuhn, Mina Peryanova, Helene Heidegger, Kerstin Hermelink, Doris Mayr, Sven Mahner, Christian Dannecker, Udo Jeschke,  and Bernd Kost
105356-105371
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Sensitization of lung cancer cells by altered dimerization of HSP27

Sensitization of lung cancer cells by altered dimerization of HSP27

https://doi.org/10.18632/oncotarget.22192

Byeol Choi, Seul-Ki Choi, You Na Park, Soo-Yeon Kwak, Hwa Jeong Lee, Youngjoo Kwon, Younghwa Na,  and Yun-Sil Lee
105372-105382
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Mek activity is required for ErbB2 expression in breast cancer cells detached from the extracellular matrix

Mek activity is required for ErbB2 expression in breast cancer cells detached from the extracellular matrix

https://doi.org/10.18632/oncotarget.22194

Iman A. Khan, Byong H. Yoo, Janusz Rak,  and Kirill V. Rosen
105383-105396
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

CD20 expression sub-stratifies standard-risk patients with B cell precursor acute lymphoblastic leukemia

CD20 expression sub-stratifies standard-risk patients with B cell precursor acute lymphoblastic leukemia

https://doi.org/10.18632/oncotarget.22207

ShenMiao Yang, Jing Wang, Ting Zhao, JinSong Jia, HongHu Zhu, Hao Jiang, Jin Lu, Bin Jiang, HongXia Shi, YanRong Liu, YueYun Lai, LanPing Xu, XiaoJun Huang,  and Qian Jiang
105397-105406
Abstract  |  PDF  |  HTML  |  Order a Reprint

Genetic variations of NTCP are associated with susceptibility to HBV infection and related hepatocellular carcinoma

Genetic variations of NTCP are associated with susceptibility to HBV infection and related hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.22211

Peng Wang, Ruidong Mo, Rongtao Lai, Yumin Xu, Jie Lu, Gangde Zhao, Yuhan Liu, Zhujun Cao, Xiaolin Wang, Ziqiang Li, Lanyi Lin, Huijuan Zhou, Wei Cai, Hui Wang, Shisan Bao, Xiaogang Xiang,  and Qing Xie
105407-105424
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Use of autoantibodies against tumor-associated antigens as serum biomarkers for primary screening of cervical cancer

Use of autoantibodies against tumor-associated antigens as serum biomarkers for primary screening of cervical cancer

https://doi.org/10.18632/oncotarget.22231

Yingji Jin, Seung Cheol Kim, Hyoung Jin Kim, Woong Ju, Yun Hwan Kim,  and Hong-Jin Kim
105425-105439
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Nuclear membrane-localised NOX4D generates pro-survival ROS in FLT3-ITD-expressing AML

Nuclear membrane-localised NOX4D generates pro-survival ROS in FLT3-ITD-expressing AML

https://doi.org/10.18632/oncotarget.22241

Jennifer N. Moloney, Ashok Kumar Jayavelu, Joanna Stanicka, Sarah L. Roche, Rebecca L. O’Brien, Sebastian Scholl, Frank-D. Böhmer,  and Thomas G. Cotter
105440-105457
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Predicting castration-resistant prostate cancer after combined androgen blockade

Predicting castration-resistant prostate cancer after combined androgen blockade

https://doi.org/10.18632/oncotarget.22246

Miao He, Haina Liu, Jingyi Cao, Qian Wang, Haiting Xu,  and Yufeng Wang
105458-105462
Abstract  |  PDF  |  HTML  |  Order a Reprint

Decreased incidence of glaucoma in children with asthma using inhaled corticosteroid: a cohort study

Decreased incidence of glaucoma in children with asthma using inhaled corticosteroid: a cohort study

https://doi.org/10.18632/oncotarget.22252

Ling-Sai Chang, Hui-Ching Lee, Yuh-Chyn Tsai, Lien-Shi Shen, Ching-Ling Li, Shih-Feng Liu,  and Ho-Chang Kuo
105463-105471
Abstract  |  PDF  |  HTML  |  Order a Reprint

Role of VEGFA gene polymorphisms in colorectal cancer patients who treated with bevacizumab

Role of VEGFA gene polymorphisms in colorectal cancer patients who treated with bevacizumab

https://doi.org/10.18632/oncotarget.22295

Wei Cui, Feng Li, Qiang Yuan, Gang Chen, Cailing Chen,  and Bo Yu
105472-105478
Abstract  |  PDF  |  HTML  |  Order a Reprint

Characterization of the efficacies of osimertinib and nazartinib against cells expressing clinically relevant epidermal growth factor receptor mutations

Characterization of the efficacies of osimertinib and nazartinib against cells expressing clinically relevant epidermal growth factor receptor mutations

https://doi.org/10.18632/oncotarget.22297

Keita Masuzawa, Hiroyuki Yasuda, Junko Hamamoto, Shigenari Nukaga, Toshiyuki Hirano, Ichiro Kawada, Katsuhiko Naoki, Kenzo Soejima,  and Tomoko Betsuyaku
105479-105491
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A molecular signature of lung cancer: potential biomarkers for adenocarcinoma and squamous cell carcinoma

A molecular signature of lung cancer: potential biomarkers for adenocarcinoma and squamous cell carcinoma

https://doi.org/10.18632/oncotarget.22298

Varda Shoshan-Barmatz, Yael Bishitz, Avijit Paul, Yakov Krelin, Itay Nakdimon, Nir Peled, Avia Lavon, Elina Rudoy-Zilberman,  and Yael Refaely
105492-105509
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Reactive oxygen species levels control NF-κB activation by low dose deferasirox in erythroid progenitors of low risk myelodysplastic syndromes

Reactive oxygen species levels control NF-κB activation by low dose deferasirox in erythroid progenitors of low risk myelodysplastic syndromes

https://doi.org/10.18632/oncotarget.22299

Mathieu Meunier, Sarah Ancelet, Christine Lefebvre, Josiane Arnaud, Catherine Garrel, Mylène Pezet, Yan Wang, Patrice Faure, Gautier Szymanski, Nicolas Duployez, Claude Preudhomme, Denis Biard, Benoit Polack, Jean-Yves Cahn, Jean Marc Moulis,  and Sophie Park
105510-105524
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

SphK2 over-expression promotes osteosarcoma cell growth

SphK2 over-expression promotes osteosarcoma cell growth

https://doi.org/10.18632/oncotarget.22314

Dawei Xu, Hao Zhu, Chengniu Wang, Wei Zhao, Genxiang Liu, Guofeng Bao, Daoran Cui, Jianbo Fan, Fei Wang, Huricha Jin,  and Zhiming Cui
105525-105535
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Metformin alleviates nickel-induced autophagy and apoptosis via inhibition of hexokinase-2, activating lipocalin-2, in human bronchial epithelial cells

Metformin alleviates nickel-induced autophagy and apoptosis via inhibition of hexokinase-2, activating lipocalin-2, in human bronchial epithelial cells

https://doi.org/10.18632/oncotarget.22317

Yu-Ting Kang, Wen-Cheng Hsu, Chih-Hsien Wu, I-Lun Hsin, Pei-Ru Wu, Kun-Tu Yeh,  and Jiunn-Liang Ko
105536-105552
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Identification of a three miRNA signature as a novel potential prognostic biomarker in patients with bladder cancer

Identification of a three miRNA signature as a novel potential prognostic biomarker in patients with bladder cancer

https://doi.org/10.18632/oncotarget.22318

Fei Peng, Hui Li, Hailang Xiao, Ling Li, Yan Li,  and Yi Wu
105553-105560
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Baicalein suppresses the androgen receptor (AR)-mediated prostate cancer progression via inhibiting the AR N-C dimerization and AR-coactivators interaction

Baicalein suppresses the androgen receptor (AR)-mediated prostate cancer progression via inhibiting the AR N-C dimerization and AR-coactivators interaction

https://doi.org/10.18632/oncotarget.22319

Defeng Xu, Qiulu Chen, Yalin Liu,  and Xingqiao Wen
105561-105573
Abstract  |  PDF  |  HTML  |  Order a Reprint

The meta and bioinformatics analysis of fascin expression in gastric cancer: a potential marker for aggressiveness and worse prognosis

The meta and bioinformatics analysis of fascin expression in gastric cancer: a potential marker for aggressiveness and worse prognosis

https://doi.org/10.18632/oncotarget.22325

Hua-Chuan Zheng,  and Shuang Zhao
105574-105583
Abstract  |  PDF  |  HTML  |  Order a Reprint

Lipopolysaccharide-coated CuS nanoparticles promoted anti-cancer and anti-metastatic effect by immuno-photothermal therapy

Lipopolysaccharide-coated CuS nanoparticles promoted anti-cancer and anti-metastatic effect by immuno-photothermal therapy

https://doi.org/10.18632/oncotarget.22331

Bian Jang, Li Xu, Madhappan S. Moorthy, Wei Zhang, Ling Zeng, Mingyeong Kang, Minseok Kwak, Junghwan Oh,  and Jun-O Jin
105584-105595
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Apatinib is effective for treatment of advanced hepatocellular carcinoma

Apatinib is effective for treatment of advanced hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.22337

Yinlong Kong, Lin Sun, Zhenyu Hou, Yongqiang Zhang, Ping Chen, Yunlong Cui, Xiaolin Zhu, Tianqiang Song, Qiang Li, Huikai Li, Ti Zhang,  and Lunxiu Qin
105596-105605
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Pilot study: molecular risk factors for diagnosing sporadic Parkinson's disease based on gene expression in blood in MPTP-induced rhesus monkeys

Pilot study: molecular risk factors for diagnosing sporadic Parkinson's disease based on gene expression in blood in MPTP-induced rhesus monkeys

https://doi.org/10.18632/oncotarget.22348

Liangqin Shi, Chao Huang, Qihui Luo, Yu Xia, Heng Liu, Like Li, Wentao Liu, Wenjing Ma, Jing Fang, Li Tang, Wen Zeng,  and Zhengli Chen
105606-105614
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Indirubin, a bisindole alkaloid from Isatis indigotica, reduces H1N1 susceptibility in stressed mice by regulating MAVS signaling

Indirubin, a bisindole alkaloid from Isatis indigotica, reduces H1N1 susceptibility in stressed mice by regulating MAVS signaling

https://doi.org/10.18632/oncotarget.22350

Chong Jie, Zhuo Luo, Huan Chen, Min Wang, Chang Yan, Zhong-Fu Mao, Gao-Keng Xiao, Hiroshi Kurihara, Yi-Fang Li,  and Rong-Rong He
105615-105629
Abstract  |  PDF  |  HTML  |  Order a Reprint

Relationship between expression of cyclooxygenase 2 and neovascularization in human pterygia

Relationship between expression of cyclooxygenase 2 and neovascularization in human pterygia

https://doi.org/10.18632/oncotarget.22351

Dongwei Liu, Chang Peng, Zhengxuan Jiang,  and Liming Tao
105630-105636
Abstract  |  PDF  |  HTML  |  Order a Reprint

Survivin overexpression is potentially associated with pituitary adenoma invasiveness

Survivin overexpression is potentially associated with pituitary adenoma invasiveness

https://doi.org/10.18632/oncotarget.22354

Xiangyi Kong, Shun Gong, Lijuan Su, Xinqi Cheng, Honglei Li, Tingting You,  and Yanguo Kong
105637-105647
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Altered network efficiency of functional brain networks in patients with breast cancer after chemotherapy

Altered network efficiency of functional brain networks in patients with breast cancer after chemotherapy

https://doi.org/10.18632/oncotarget.22358

Han Xuan, Chen Gan, Wen Li, Zhonglian Huang, Longsheng Wang, Qianqian Jia, Zhendong Chen,  and Huaidong Cheng
105648-105661
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Activation of Nrf2 by MIND4-17 protects osteoblasts from hydrogen peroxide-induced oxidative stress

Activation of Nrf2 by MIND4-17 protects osteoblasts from hydrogen peroxide-induced oxidative stress

https://doi.org/10.18632/oncotarget.22360

Shiguang Guo, Hao-Dong Fei, Feng Ji, Feng-Li Chen, Yue Xie,  and Shou-Guo Wang
105662-105672
Abstract  |  PDF  |  HTML  |  Order a Reprint

A green and facile preparation approach, licochalcone A capped on hollow gold nanoparticles, for improving the solubility and dissolution of anticancer natural product

A green and facile preparation approach, licochalcone A capped on hollow gold nanoparticles, for improving the solubility and dissolution of anticancer natural product

https://doi.org/10.18632/oncotarget.22387

Yi-Wei Sun, Li-Hong Wang, Da-Li Meng,  and Xin Che
105673-105681
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Diffusion-weighted MRI-derived ADC values reflect collagen I content in PDX models of uterine cervical cancer

Diffusion-weighted MRI-derived ADC values reflect collagen I content in PDX models of uterine cervical cancer

https://doi.org/10.18632/oncotarget.22388

Anette Hauge, Catherine S. Wegner, Jon-Vidar Gaustad, Trude G. Simonsen, Lise Mari K. Andersen,  and Einar K. Rofstad
105682-105691
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Activation of the NGF/TrkA signaling pathway attenuates diabetic erectile dysfunction

Activation of the NGF/TrkA signaling pathway attenuates diabetic erectile dysfunction

https://doi.org/10.18632/oncotarget.22389

Yi Hou, Linpei Jia, Ying Zhang, Wei Ji,  and Hai Li
105692-105702
Abstract  |  PDF  |  HTML  |  Order a Reprint

Ginseng Rh2 protects endometrial cells from oxygen glucose deprivation/re-oxygenation

Ginseng Rh2 protects endometrial cells from oxygen glucose deprivation/re-oxygenation

https://doi.org/10.18632/oncotarget.22390

Xiao-Fang Tang, Hai-Yan Liu, Ling Wu, Min-Hui Li, Shu-Ping Li,  and Hong-Bin Xu
105703-105713
Abstract  |  PDF  |  HTML  |  Order a Reprint

MutT-related proteins are novel progression and prognostic markers for colorectal cancer

MutT-related proteins are novel progression and prognostic markers for colorectal cancer

https://doi.org/10.18632/oncotarget.22393

Jin Li, Cheng-Cheng Yang, Xin-Yuan Tian, Yun-Xuan Li, Ju Cui, Zhe Chen, Zhou-Lu Deng, Fu-Jun Chen, Hiroshi Hayakawa, Jian-Ping Cai,  and Jian-Ping Cai
105714-105726
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MerTK inhibition by RXDX-106 in MerTK activated gastric cancer cell lines

MerTK inhibition by RXDX-106 in MerTK activated gastric cancer cell lines

https://doi.org/10.18632/oncotarget.22394

Jung Eun Kim, Youjin Kim, Gary Li, Seung Tae Kim, Kyung Kim, Se Hoon Park, Joon Oh Park, Young Suk Park, Ho Yeong Lim, Hyuk Lee, Tae Sung Sohn, Kyoung-Mee Kim, Won Ki Kang,  and Jeeyun Lee
105727-105734
Abstract  |  PDF  |  HTML  |  Order a Reprint

Synthetic nickel-containing superoxide dismutase attenuates para-phenylenediamine-induced bladder dysfunction in rats

Synthetic nickel-containing superoxide dismutase attenuates para-phenylenediamine-induced bladder dysfunction in rats

https://doi.org/10.18632/oncotarget.22395

Bing-Juin Chiang, Tien-Wen Chen, Shiu-Dong Chung, Way-Zen Lee,  and Chiang-Ting Chien
105735-105748
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Exploring the effect of primary tumor sidedness on therapeutic efficacy across treatment lines in patients with metastatic colorectal cancer: analysis of FIRE-3 (AIOKRK0306)

Exploring the effect of primary tumor sidedness on therapeutic efficacy across treatment lines in patients with metastatic colorectal cancer: analysis of FIRE-3 (AIOKRK0306)

https://doi.org/10.18632/oncotarget.22396

Dominik Paul Modest, Sebastian Stintzing, Ludwig Fischer von Weikersthal, Thomas Decker, Alexander Kiani, Ursula Vehling-Kaiser, Salah-Eddin Al-Batran, Tobias Heintges, Christoph Kahl, Gernot Seipelt, Frank Kullmann, Werner Scheithauer, Markus Moehler, Julian Walter Holch, Jobst von Einem, Swantje Held,  and Volker Heinemann
105749-105760
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Preliminary quantitative proteomics analysis in chronic and latent Keshan disease by iTRAQ labeling approach

Preliminary quantitative proteomics analysis in chronic and latent Keshan disease by iTRAQ labeling approach

https://doi.org/10.18632/oncotarget.22397

Yuxiao Sun, Chuanyu Gao, Xianqing Wang,  and Yuhao Liu
105761-105774
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Serum SDF-1 levels are a reliable diagnostic marker of feline mammary carcinoma, discriminating HER2-overexpressing tumors from other subtypes

Serum SDF-1 levels are a reliable diagnostic marker of feline mammary carcinoma, discriminating HER2-overexpressing tumors from other subtypes

https://doi.org/10.18632/oncotarget.22398

Cláudia S. Marques, Maria Soares, Ana Santos, Jorge Correia,  and Fernando Ferreira
105775-105789
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Development of a novel biomarker model for predicting preoperative lymph node metastatic extent in esophageal squamous cell carcinoma1

Development of a novel biomarker model for predicting preoperative lymph node metastatic extent in esophageal squamous cell carcinoma1

https://doi.org/10.18632/oncotarget.22399

Zhao Ma, Xianxian Wu, Bo Xu, Hongjing Jiang, Peng Tang, Jie Yue, Mingquan Ma, Chuangui Chen, Hongdian Zhang,  and Zhentao Yu
105790-105799
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Two new species of betatorqueviruses identified in a human melanoma that metastasized to the brain

Two new species of betatorqueviruses identified in a human melanoma that metastasized to the brain

https://doi.org/10.18632/oncotarget.22400

Terry Fei Fan Ng, Jennifer A. Dill, Alvin C. Camus, Eric Delwart,  and Erwin G. Van Meir
105800-105808
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Usefulness of plasma matrix metalloproteinase-9 levels in prediction of in-hospital mortality in patients who received emergent percutaneous coronary artery intervention following myocardial infarction

Usefulness of plasma matrix metalloproteinase-9 levels in prediction of in-hospital mortality in patients who received emergent percutaneous coronary artery intervention following myocardial infarction

https://doi.org/10.18632/oncotarget.22401

Jia-Jun Zhu, Qian Zhao, Hui-Juan Qu, Xiao-Mei Li, Qing-Jie Chen, Fen Liu, Bang-Dang Chen,  and Yi-Ning Yang
105809-105818
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NMR-based metabolomic techniques identify potential urinary biomarkers for early colorectal cancer detection

NMR-based metabolomic techniques identify potential urinary biomarkers for early colorectal cancer detection

https://doi.org/10.18632/oncotarget.22402

Zhening Wang, Yan Lin, Jiahao Liang, Yao Huang, Changchun Ma, Xingmu Liu,  and Jurong Yang
105819-105831
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RNA-sequencing reveals genome-wide long non-coding RNAs profiling associated with early development of diabetic nephropathy

RNA-sequencing reveals genome-wide long non-coding RNAs profiling associated with early development of diabetic nephropathy

https://doi.org/10.18632/oncotarget.22405

Wanxin Tang, Dongmei Zhang,  and Xiaoke Ma
105832-105847
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Identification of WT1 as determinant of heptatocellular carcinoma and its inhibition by Chinese herbal medicine Salvia chinensis Benth and its active ingredient protocatechualdehyde

Identification of WT1 as determinant of heptatocellular carcinoma and its inhibition by Chinese herbal medicine Salvia chinensis Benth and its active ingredient protocatechualdehyde

https://doi.org/10.18632/oncotarget.22406

Ning Wang, Hor-Yue Tan, Yau-Tuen Chan, Wei Guo, Sha Li,  and Yibin Feng
105848-105859
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Andrographolide suppresses the migratory ability of human glioblastoma multiforme cells by targeting ERK1/2-mediated matrix metalloproteinase-2 expression

Andrographolide suppresses the migratory ability of human glioblastoma multiforme cells by targeting ERK1/2-mediated matrix metalloproteinase-2 expression

https://doi.org/10.18632/oncotarget.22407

Shih-Liang Yang, Fu-Hsuan Kuo, Pei-Ni Chen, Yi-Hsien Hsieh, Nuo-Yi Yu, Wei-En Yang, Ming-Ju Hsieh,  and Shun-Fa Yang
105860-105872
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MiR-20a-5p promotes radio-resistance by targeting NPAS2 in nasopharyngeal cancer cells

MiR-20a-5p promotes radio-resistance by targeting NPAS2 in nasopharyngeal cancer cells

https://doi.org/10.18632/oncotarget.22411

Fangfang Zhao, Youguang Pu, Liting Qian, Chunbao Zang, Zhenchao Tao,  and Jin Gao
105873-105881
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Renal oncocytoma characterized by the defective complex I of the respiratory chain boosts the synthesis of the ROS scavenger glutathione

Renal oncocytoma characterized by the defective complex I of the respiratory chain boosts the synthesis of the ROS scavenger glutathione

https://doi.org/10.18632/oncotarget.22413

Gerrit Kürschner, Qingzhou Zhang, Rosanna Clima, Yi Xiao, Jonas Felix Busch, Ergin Kilic, Klaus Jung, Nikolaus Berndt, Sascha Bulik, Hermann-Georg Holzhütter, Giuseppe Gasparre, Marcella Attimonelli, Mohan Babu,  and David Meierhofer
105882-105904
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

GSTT1, GSTP1, and GSTM1 genetic variants are associated with survival in previously untreated metastatic breast cancer

GSTT1, GSTP1, and GSTM1 genetic variants are associated with survival in previously untreated metastatic breast cancer

https://doi.org/10.18632/oncotarget.22450

Jian Zhang, Ying Wu, Xichun Hu, Biyun Wang, Leiping Wang, Sheng Zhang, Jun Cao,  and Zhonghua Wang
105905-105914
Abstract  |  PDF  |  HTML  |  Order a Reprint

Telomere length associated with the risks of high-risk and ischemic stroke in southern Chinese Han population

Telomere length associated with the risks of high-risk and ischemic stroke in southern Chinese Han population

https://doi.org/10.18632/oncotarget.22509

Dong Luo, Qun Hou, Jianzhong Yu,  and Dan Yu
105915-105922
Abstract  |  PDF  |  HTML  |  Order a Reprint

Insulin receptor substrate-4 interacts with ubiquitin-specific protease 18 to activate the Jak/STAT signaling pathway

Insulin receptor substrate-4 interacts with ubiquitin-specific protease 18 to activate the Jak/STAT signaling pathway

https://doi.org/10.18632/oncotarget.22510

Baihai Jiao, Xuezhen Shi, Yanzhao Chen, Haiyan Ye, Min Yao, Wenxu Hong, Shilin Li, Xiaoqiong Duan, Yujia Li, Yancui Wang,  and Limin Chen
105923-105935
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Elevated CEA is associated with worse survival in recurrent rectal cancer

Elevated CEA is associated with worse survival in recurrent rectal cancer

https://doi.org/10.18632/oncotarget.22511

Won Kyung Cho, Doo Ho Choi, Hee Chul Park, Won Park, Jeong Il Yu, Young Suk Park, Joon Oh Park, Ho Yeong Lim, Won Ki Kang, Hee Cheol Kim, Yong Beom Cho, Seong Hyeon Yun,  and Woo Yong Lee
105936-105941
Abstract  |  PDF  |  HTML  |  Order a Reprint

A premature stop codon within the tvb receptor gene results in decreased susceptibility to infection by avian leukosis virus subgroups B, D, and E

A premature stop codon within the tvb receptor gene results in decreased susceptibility to infection by avian leukosis virus subgroups B, D, and E

https://doi.org/10.18632/oncotarget.22512

WeiGuo Chen, Yang Liu, Aijun Li, Xinjian Li, Hongxing Li, Zhenkai Dai, Yiming Yan, Xinheng Zhang, Dingming Shu, Huanmin Zhang, Wencheng Lin, Jingyun Ma,  and Qingmei Xie
105942-105956
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HLA-G+3027 polymorphism is associated with tumor relapse in pediatric Hodgkin’s lymphoma

HLA-G+3027 polymorphism is associated with tumor relapse in pediatric Hodgkin’s lymphoma

https://doi.org/10.18632/oncotarget.22515

Valli De Re, Laura Caggiari, Lara Mussolin, Emanuele Stefano d’Amore, Barbara Famengo, Mariangela De Zorzi, Lia Martina, Caterina Elia, Marta Pillon, Nicola Santoro, Paola Muggeo, Salvatore Buffardi, Maurizio Bianchi, Alessandra Sala, Piero Farruggia, Luciana Vinti, Edgardo D. Carosella, Roberta Burnelli,  and Maurizio Mascarin
105957-105970
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Polymorphisms in matrix metalloproteinases 2, 3, and 8 increase recurrence and mortality risk by regulating enzyme activity in gastric adenocarcinoma

Polymorphisms in matrix metalloproteinases 2, 3, and 8 increase recurrence and mortality risk by regulating enzyme activity in gastric adenocarcinoma

https://doi.org/10.18632/oncotarget.22516

Youdong Lin, Jinsheng Liu, Long Jin,  and Yun Jiang
105971-105983
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Decisive role of P42/44 mitogen-activated protein kinase in Δ9-tetrahydrocannabinol-induced migration of human mesenchymal stem cells

Decisive role of P42/44 mitogen-activated protein kinase in Δ9-tetrahydrocannabinol-induced migration of human mesenchymal stem cells

https://doi.org/10.18632/oncotarget.22517

Ellen Lüder, Robert Ramer, Kirsten Peters,  and Burkhard Hinz
105984-105994
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1,8-cineole prevents UVB-induced skin carcinogenesis by targeting the aryl hydrocarbon receptor

1,8-cineole prevents UVB-induced skin carcinogenesis by targeting the aryl hydrocarbon receptor

https://doi.org/10.18632/oncotarget.22519

Jangho Lee, Su Jeong Ha, Joon Park, Yong Ho Kim, Nam Hyouck Lee, Young Eon Kim, Yoonsook Kim, Kyung-Mo Song,  and Sung Keun Jung
105995-106008
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Role of preoperative magnetic resonance imaging and histological assessment in identifying patients with a low risk of endometrial cancer: a Korean Gynecologic Oncology Group ancillary study

Role of preoperative magnetic resonance imaging and histological assessment in identifying patients with a low risk of endometrial cancer: a Korean Gynecologic Oncology Group ancillary study

https://doi.org/10.18632/oncotarget.22520

Jung-Yun Lee, Yun Hwan Kim, Jong-Min Lee, Kidong Kim, Sokbom Kang, Myong Cheol Lim, Beob-Jong Kim, Bang Hyun Lee,  and Jae Weon Kim
106009-106016
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Gene delivery and gene expression in vertebrate using baculovirus Bombyx mori nucleopolyhedrovirus vector

Gene delivery and gene expression in vertebrate using baculovirus Bombyx mori nucleopolyhedrovirus vector

https://doi.org/10.18632/oncotarget.22522

Xingjian Liu, Yinü Li, Xiaoyuan Hu, Yongzhu Yi,  and Zhifang Zhang
106017-106025
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RTL1 promotes melanoma proliferation by regulating Wnt/β-catenin signalling

RTL1 promotes melanoma proliferation by regulating Wnt/β-catenin signalling

https://doi.org/10.18632/oncotarget.22523

Guobiao Fan, Dan Ye, Songcheng Zhu, Jiajie Xi, Xudong Guo, Jing Qiao, Yukang Wu, Wenwen Jia, Guiying Wang, Guohuang Fan,  and Jiuhong Kang
106026-106037
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FAM3C activates HSF1 to suppress hepatic gluconeogenesis and attenuate hyperglycemia of type 1 diabetic mice

FAM3C activates HSF1 to suppress hepatic gluconeogenesis and attenuate hyperglycemia of type 1 diabetic mice

https://doi.org/10.18632/oncotarget.22524

Zhenzhen Chen, Junpei Wang, Weili Yang, Ji Chen, Yuhong Meng, Biaoqi Feng, Yujing Chi, Bin Geng, Yong Zhou, Qinghua Cui,  and Jichun Yang
106038-106049
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TLR2/MyD88 pathway-dependent regulation of dendritic cells by dengue virus promotes antibody-dependent enhancement via Th2-biased immunity

TLR2/MyD88 pathway-dependent regulation of dendritic cells by dengue virus promotes antibody-dependent enhancement via Th2-biased immunity

https://doi.org/10.18632/oncotarget.22525

Junu Aleyas George, Seong Bum Kim, Jin Young Choi, Ajit Mahadev Patil, Ferdaus Mohd Altaf Hossain, Erdenebelig Uyangaa, Jin Hur, Sang-Youel Park, John-Hwa Lee, Koanhoi Kim,  and Seong Kug Eo
106050-106070
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CXCL8 derived from tumor-associated macrophages and esophageal squamous cell carcinomas contributes to tumor progression by promoting migration and invasion of cancer cells

CXCL8 derived from tumor-associated macrophages and esophageal squamous cell carcinomas contributes to tumor progression by promoting migration and invasion of cancer cells

https://doi.org/10.18632/oncotarget.22526

Masayoshi Hosono, Yu-Ichiro Koma, Nobuhisa Takase, Naoki Urakawa, Nobuhide Higashino, Kazuki Suemune, Himiko Kodaira, Mari Nishio, Manabu Shigeoka, Yoshihiro Kakeji,  and Hiroshi Yokozaki
106071-106088
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Elevated pretreatment platelet distribution width and platelet count predict poor prognosis in nasopharyngeal carcinoma

Elevated pretreatment platelet distribution width and platelet count predict poor prognosis in nasopharyngeal carcinoma

https://doi.org/10.18632/oncotarget.22528

XueCheng Xie, XiaoChun Zeng, SuJuan Cao, XiaoMao Hu, QiaoJing Shi, Dan Li, ShiYuan Zhou, Ping Gu,  and ZhongShan Zhang
106089-106097
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Altered expression of differential gene and lncRNA in the lower thoracic spinal cord on different time courses of experimental obstructive jaundice model accompanied with altered peripheral nociception in rats

Altered expression of differential gene and lncRNA in the lower thoracic spinal cord on different time courses of experimental obstructive jaundice model accompanied with altered peripheral nociception in rats

https://doi.org/10.18632/oncotarget.22532

Qian Wang, Zhi-Xiao Li, Bao-Wen Liu, Zhi-Gang He, Cheng Liu, Min Chen, San-Guang Liu, Wei-Zhong Wu,  and Hong-Bing Xiang
106098-106112
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Clinical Research Papers

Comparison of hydrocortisone and prednisone in the glucocorticoid replacement therapy post-adrenalectomy of Cushing’s Syndrome

Comparison of hydrocortisone and prednisone in the glucocorticoid replacement therapy post-adrenalectomy of Cushing’s Syndrome

https://doi.org/10.18632/oncotarget.20597

Kunlong Tang, Liang Wang, Zhongyuan Yang, Yingying Sui, Liming Li, Yuting Huang,  and Peng Gao
106113-106120
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Impact of socioeconomic status on survival of colorectal cancer patients

Impact of socioeconomic status on survival of colorectal cancer patients

https://doi.org/10.18632/oncotarget.20859

Qian Zhang, Yufu Wang, Hanqing Hu, Rui Huang, Lei Xie, Enrui Liu, Ying-Gang Chen, Guiyu Wang,  and Xishan Wang
106121-106131
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Reviews

Immune system and melanoma biology: a balance between immunosurveillance and immune escape

Immune system and melanoma biology: a balance between immunosurveillance and immune escape

https://doi.org/10.18632/oncotarget.22190

Anna Passarelli, Francesco Mannavola, Luigia Stefania Stucci, Marco Tucci,  and Francesco Silvestris
106132-106142
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