Oncotarget

Vol 8, No 42

September 22, 2017

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About The Cover

The cover for issue 42 of Oncotarget features Figure 3, "Comparable affordability of 8 patented cancer drugs in 7 countries," from Goldstein, et al.

Table of Contents

Research Papers

Selective DNA methylation in cancers controls collateral damage induced by large structural variations

Selective DNA methylation in cancers controls collateral damage induced by large structural variations

https://doi.org/10.18632/oncotarget.10487

Vakul Mohanty, Ogulsheker Akmamedova,  and Kakajan Komurov
71385-71392
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Racial differences in prostate inflammation: results from the REDUCE study

Racial differences in prostate inflammation: results from the REDUCE study

https://doi.org/10.18632/oncotarget.10690

Adriana C. Vidal, Zinan Chen, Lauren E. Howard, Daniel M. Moreira, Ramiro Castro-Santamaria, Gerald L. Andriole, Emanuela Taioli, Jay H. Fowke, Beatrice Knudsen, Charles G. Drake, J. Curtis Nickel,  and Stephen J. Freedland
71393-71399
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Inhibition of extracellular matrix mediated TGF-β signalling suppresses endometrial cancer metastasis

Inhibition of extracellular matrix mediated TGF-β signalling suppresses endometrial cancer metastasis

https://doi.org/10.18632/oncotarget.18069

Subhransu S. Sahoo, Min Yuan Quah, Sarah Nielsen, Joshua Atkins, Gough G. Au, Murray J. Cairns, Pravin Nahar, Janine M. Lombard,  and Pradeep S. Tanwar
71400-71417
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

miR-338-3p inhibits epithelial-mesenchymal transition and metastasis in hepatocellular carcinoma cells

miR-338-3p inhibits epithelial-mesenchymal transition and metastasis in hepatocellular carcinoma cells

https://doi.org/10.18632/oncotarget.10138

Jing-Song Chen, Li-Li Liang, Hong-Xu Xu, Fan Chen, Shun-Li Shen, Wei Chen, Lian-Zhou Chen, Qiao Su, Long-Juan Zhang, Jiong Bi, Wen-Tao Zeng, Wen Li, Ning Ma,  and Xiao-Hui Huang
71418-71429
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Integrated analysis of dosage effect lncRNAs in lung adenocarcinoma based on comprehensive network

Integrated analysis of dosage effect lncRNAs in lung adenocarcinoma based on comprehensive network

https://doi.org/10.18632/oncotarget.19864

Yunzhen Wei, Zichuang Yan, Cheng Wu, Qiang Zhang, Yinling Zhu, Kun Li,  and Yan Xu
71430-71446
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Androgen receptor amplification is concordant between circulating tumor cells and biopsies from men undergoing treatment for metastatic castration resistant prostate cancer

Androgen receptor amplification is concordant between circulating tumor cells and biopsies from men undergoing treatment for metastatic castration resistant prostate cancer

https://doi.org/10.18632/oncotarget.16169

Jennifer Podolak, Kristi Eilers, Timothy Newby, Rachel Slottke, Erin Tucker, Susan B. Olson, Hui-Wen Lue, Jack Youngren, Rahul Aggarwal, Eric J. Small, Julie N. Graff, Joshi J. Alumkal, Tomasz M. Beer,  and George V. Thomas
71447-71455
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MUC2 mucin deficiency alters inflammatory and metabolic pathways in the mouse intestinal mucosa

MUC2 mucin deficiency alters inflammatory and metabolic pathways in the mouse intestinal mucosa

https://doi.org/10.18632/oncotarget.16886

Selamawit Tadesse, Georgia Corner, Elena Dhima, Michele Houston, Chandan Guha, Leonard Augenlicht,  and Anna Velcich
71456-71470
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Reduced production and uptake of lactate are essential for the ability of WNT5A signaling to inhibit breast cancer cell migration and invasion

Reduced production and uptake of lactate are essential for the ability of WNT5A signaling to inhibit breast cancer cell migration and invasion

https://doi.org/10.18632/oncotarget.17277

Chandra Prakash Prasad, Katja Södergren,  and Tommy Andersson
71471-71488
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Evolutionary cancer-favoring engineered vaccinia virus for metastatic hepatocellular carcinoma

Evolutionary cancer-favoring engineered vaccinia virus for metastatic hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.17288

So Young Yoo, Su-Nam Jeong, Dae Hwan Kang,  and Jeong Heo
71489-71499
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Repression of SUMOylation pathway by grass carp reovirus contributes to the upregulation of PKR in an IFN-independent manner

Repression of SUMOylation pathway by grass carp reovirus contributes to the upregulation of PKR in an IFN-independent manner

https://doi.org/10.18632/oncotarget.20309

Fei Yu, Longlong Wang, Hao Wang, Jialu Sheng,  and Liqun Lu
71500-71511
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Repurposing Albendazole: new potential as a chemotherapeutic agent with preferential activity against HPV-negative head and neck squamous cell cancer

Repurposing Albendazole: new potential as a chemotherapeutic agent with preferential activity against HPV-negative head and neck squamous cell cancer

https://doi.org/10.18632/oncotarget.17292

Farhad Ghasemi, Morgan Black, Frederick Vizeacoumar, Nicole Pinto, Kara M. Ruicci, Carson Cao Son Huu Le, Matthew R. Lowerison, Hon Sing Leong, John Yoo, Kevin Fung, Danielle MacNeil, David A. Palma, Eric Winquist, Joe S. Mymryk, Paul C. Boutros, Alessandro Datti, John W. Barrett,  and Anthony C. Nichols
71512-71519
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Association of serum Ninjurin2 levels with neurologic damage and postherpetic neuralgia occurrence: an observational cohort study in chinese herpeszoster patients

Association of serum Ninjurin2 levels with neurologic damage and postherpetic neuralgia occurrence: an observational cohort study in chinese herpeszoster patients

https://doi.org/10.18632/oncotarget.17640

Guozhuan Zhang, Yingjiao Sun, Lei Wang, Hui Tian,  and Lishuang Liang
71520-71527
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Notch4 and mhc class II polymorphisms are associated with hcv-related benign and malignant lymphoproliferative diseases

Notch4 and mhc class II polymorphisms are associated with hcv-related benign and malignant lymphoproliferative diseases

https://doi.org/10.18632/oncotarget.17655

Laura Gragnani, Elisa Fognani, Valli De Re, Massimo Libra, Adriana Garozzo, Patrizio Caini, Guia Cerretelli, Andrea Giovannelli, Serena Lorini, Monica Monti, Silvia Bagnoli, Irene Piaceri,  and Anna Linda Zignego
71528-71535
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TUBB3 overexpression has a negligible effect on the sensitivity to taxol in cultured cell lines

TUBB3 overexpression has a negligible effect on the sensitivity to taxol in cultured cell lines

https://doi.org/10.18632/oncotarget.17740

Mihoko A. Tame, Anna G. Manjón, Daria Belokhvostova, Jonne A. Raaijmakers,  and René H. Medema
71536-71547
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A global comparison of the cost of patented cancer drugs in relation to global differences in wealth

A global comparison of the cost of patented cancer drugs in relation to global differences in wealth

https://doi.org/10.18632/oncotarget.17742

Daniel A. Goldstein, Jonathon Clark, Yifan Tu, Jie Zhang, Fenqi Fang, Robert Goldstein, Salomon M. Stemmer,  and Eli Rosenbaum
71548-71555
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A single nucleotide polymorphism of AIRE gene located in the 21q22.3 increases the risk of rheumatoid arthritis

A single nucleotide polymorphism of AIRE gene located in the 21q22.3 increases the risk of rheumatoid arthritis

https://doi.org/10.18632/oncotarget.17746

Yuan-Sheng Xu, Xi-Jia Jiang,  and Jian-Min Chen
71556-71562
Abstract  |  PDF  |  HTML  |  Order a Reprint

Interleukin-35 expression is associated with colon cancer progression

Interleukin-35 expression is associated with colon cancer progression

https://doi.org/10.18632/oncotarget.17751

Jian Zhang, Tao Mao, Shuyun Wang, Dongsheng Wang, Zhaojian Niu, Zhenqing Sun,  and Jianli Zhang
71563-71573
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Inhibition of colorectal cancer genomic copy number alterations and chromosomal fragile site tumor suppressor FHIT and WWOX deletions by DNA mismatch repair

Inhibition of colorectal cancer genomic copy number alterations and chromosomal fragile site tumor suppressor FHIT and WWOX deletions by DNA mismatch repair

https://doi.org/10.18632/oncotarget.17776

Sohail Jahid, Jian Sun, Ozkan Gelincik, Pedro Blecua, Winfried Edelmann, Raju Kucherlapati, Kathy Zhou, Maria Jasin, Zeynep H. Gümüş,  and Steven M. Lipkin
71574-71586
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Profiling and bioinformatic analysis of circular RNA expression regulated by c-Myc

Profiling and bioinformatic analysis of circular RNA expression regulated by c-Myc

https://doi.org/10.18632/oncotarget.17788

Qiheng Gou, Ke Wu, Jian-Kang Zhou, Yuxin Xie, Lunxu Liu,  and Yong Peng
71587-71596
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Characterization of the transcriptional and metabolic responses of pediatric high grade gliomas to mTOR-HIF-1α axis inhibition

Characterization of the transcriptional and metabolic responses of pediatric high grade gliomas to mTOR-HIF-1α axis inhibition

https://doi.org/10.18632/oncotarget.16500

Aurélia Nguyen, François Marie Moussalieh, Alan Mackay, A. Ercument Cicek, Andres Coca, Marie Pierre Chenard, Noelle Weingertner, Benoit Lhermitte, Eric Letouzé, Eric Guérin, Erwan Pencreach, Sarah Jannier, Dominique Guenot, Izzie Jacques Namer, Chris Jones,  and Natacha Entz-Werlé
71597-71617
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

CDK1 interacts with iASPP to regulate colorectal cancer cell proliferation through p53 pathway

CDK1 interacts with iASPP to regulate colorectal cancer cell proliferation through p53 pathway

https://doi.org/10.18632/oncotarget.17794

Wei Gan, Hua Zhao, Tiegang Li, Kuijie Liu,  and Jiangsheng Huang
71618-71629
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MGr1-Antigen/37 kDa laminin receptor precursor promotes cellular prion protein induced multi-drug-resistance of gastric cancer

MGr1-Antigen/37 kDa laminin receptor precursor promotes cellular prion protein induced multi-drug-resistance of gastric cancer

https://doi.org/10.18632/oncotarget.17795

Guanhong Luo, Weijie Wang, Qiong Wu, Yuanyuan Lu, Tao Su, Nan Gu, Kai Li, Jingbo Wang, Rui Du, Xiaodi Zhao, Xiaohua Li, Rui Fan, Hongbo Zhang, Yongzhan Nie, Xinmin Zhou, Yongquan Shi, Jie Liang, Xin Wang,  and Daiming Fan
71630-71641
Abstract  |  PDF  |  HTML  |  Order a Reprint

HMGB1-mediated autophagy attenuates gemcitabine-induced apoptosis in bladder cancer cells involving JNK and ERK activation

HMGB1-mediated autophagy attenuates gemcitabine-induced apoptosis in bladder cancer cells involving JNK and ERK activation

https://doi.org/10.18632/oncotarget.17796

Hubin Yin, Xiaoyu Yang, Wen Gu, Yan Liu, Xinyuan Li, Xiaolong Huang, Xin Zhu, Yong Tao, Xin Gou,  and Weiyang He
71642-71656
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A novel synthetic derivative of quercetin, 8-trifluoromethyl-3,5,7,3′,4′-O-pentamethyl-quercetin, inhibits bladder cancer growth by targeting the AMPK/mTOR signaling pathway

A novel synthetic derivative of quercetin, 8-trifluoromethyl-3,5,7,3′,4′-O-pentamethyl-quercetin, inhibits bladder cancer growth by targeting the AMPK/mTOR signaling pathway

https://doi.org/10.18632/oncotarget.17799

Ting Tao, Caimei He, Jun Deng, Yanjun Huang, Qiongli Su, Mei Peng, Meiling Yi, Kwame Oteng Darko, Hui Zou,  and Xiaoping Yang
71657-71671
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Functional heterogeneity in tumor-derived human pancreatic stellate cells: Differential expression of HGF and implications for mitogenic signaling and migration in pancreatic cancer cells

Functional heterogeneity in tumor-derived human pancreatic stellate cells: Differential expression of HGF and implications for mitogenic signaling and migration in pancreatic cancer cells

https://doi.org/10.18632/oncotarget.17800

Vegard Tjomsland, Monica Aasrum, Thoralf Christoffersen,  and Ivar P. Gladhaug
71672-71684
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Hematopoietic transcription factors and differential cofactor binding regulate PRKACB isoform expression

Hematopoietic transcription factors and differential cofactor binding regulate PRKACB isoform expression

https://doi.org/10.18632/oncotarget.17386

Olga N. Kuvardina, Stefanie Herkt, Annekarin Meyer, Lucas Schneider, Jasmin Yillah, Nicole Kohrs, Halvard Bonig, Erhard Seifried, Carsten Müller-Tidow,  and Jörn Lausen
71685-71698
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A nation-wide retrospective epidemiological study of gastroenteropancreatic neuroendocrine neoplasms in china

A nation-wide retrospective epidemiological study of gastroenteropancreatic neuroendocrine neoplasms in china

https://doi.org/10.18632/oncotarget.17599

Jin-Hu Fan, Yu-Qing Zhang, Su-Sheng Shi, Yuan-Jia Chen, Xing-Hua Yuan, Li-Ming Jiang, Shao-Ming Wang, Li Ma, Yu-Tong He, Chang-Yan Feng, Xi-Bin Sun, Qing Liu, Katrina Deloso, Yihebali Chi,  and You-Lin Qiao
71699-71708
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Blockage of FOXP3 transcription factor dimerization and FOXP3/AML1 interaction inhibits T regulatory cell activity: sequence optimization of a peptide inhibitor

Blockage of FOXP3 transcription factor dimerization and FOXP3/AML1 interaction inhibits T regulatory cell activity: sequence optimization of a peptide inhibitor

https://doi.org/10.18632/oncotarget.17845

Teresa Lozano, Marta Gorraiz, Aritz Lasarte-Cía, Marta Ruiz, Obdulia Rabal, Julen Oyarzabal, Sandra Hervás-Stubbs, Diana Llopiz, Pablo Sarobe, Jesús Prieto, Noelia Casares,  and Juan José Lasarte
71709-71724
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

B7-H3 promotes gastric cancer cell migration and invasion

B7-H3 promotes gastric cancer cell migration and invasion

https://doi.org/10.18632/oncotarget.17847

Yecheng Li, Xiaodong Yang, Yong Wu, Kui Zhao, Zhenyu Ye, Junjia Zhu, Xiaohui Xu, Xin Zhao,  and Chungen Xing
71725-71735
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UBE2J2 promotes hepatocellular carcinoma cell epithelial-mesenchymal transition and invasion in vitro

UBE2J2 promotes hepatocellular carcinoma cell epithelial-mesenchymal transition and invasion in vitro

https://doi.org/10.18632/oncotarget.17601

Shaopeng Chen, Ying Tan, Haihua Deng, Zhifa Shen, Yanhong Liu, Pan Wu, Chunyan Tan,  and Yuyang Jiang
71736-71749
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Determination of IL-1B (rs16944) and IL-6 (rs1800796) genetic polymorphisms in IgA nephropathy in a northwest Chinese Han population

Determination of IL-1B (rs16944) and IL-6 (rs1800796) genetic polymorphisms in IgA nephropathy in a northwest Chinese Han population

https://doi.org/10.18632/oncotarget.17603

Daofa Zhang, Maowei Xie, Xiaohong Yang, Yin Zhang, Yan Su, Yanni Wang, Haiyang Huang, Hui Han, Wenning Li, Keying Fu, Huiluan Su, Wentan Xu, Yeguang Han, Ru Wang, Pei Zhang, Wei Wu, Yun Huang, Daojun Chen, Tianbo Jin,  and Jiali Wei
71750-71758
Abstract  |  PDF  |  HTML  |  Order a Reprint

Eight potential biomarkers for distinguishing between lung adenocarcinoma and squamous cell carcinoma

Eight potential biomarkers for distinguishing between lung adenocarcinoma and squamous cell carcinoma

https://doi.org/10.18632/oncotarget.17606

Jian Xiao, Xiaoxiao Lu, Xi Chen, Yong Zou, Aibin Liu, Wei Li, Bixiu He, Shuya He,  and Qiong Chen
71759-71771
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Down-regulation of MRPS23 inhibits rat breast cancer proliferation and metastasis

Down-regulation of MRPS23 inhibits rat breast cancer proliferation and metastasis

https://doi.org/10.18632/oncotarget.17888

Yan Gao, Fuyan Li, Hong Zhou, Yi Yang, Ruimin Wu, Yijia Chen, Wei Li, Yang Li, Xueqin Xu, Changbin Ke,  and Zhijun Pei
71772-71781
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WX-132-18B, a novel microtubule inhibitor, exhibits promising anti-tumor effects

WX-132-18B, a novel microtubule inhibitor, exhibits promising anti-tumor effects

https://doi.org/10.18632/oncotarget.17710

Fang Guan, Rui Ding, Qi Zhang, Wei Chen, Feifei Li, Long Long, Wei Li, Linna Li, Dexuan Yang, Lan Xie, Shoujun Yuan,  and Lili Wang
71782-71796
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Renal cell carcinoma histological subtype distribution differs by age, gender, and tumor size in coastal Chinese patients

Renal cell carcinoma histological subtype distribution differs by age, gender, and tumor size in coastal Chinese patients

https://doi.org/10.18632/oncotarget.17894

Junlong Wu, Peipei Zhang, Guiming Zhang, Hongkai Wang, Weijie Gu, Bo Dai, Hailiang Zhang, Guohai Shi, Yijun Shen, Yiping Zhu, Yao Zhu,  and Dingwei Ye
71797-71804
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Clinical impact of high serum hepatocyte growth factor in advanced non-small cell lung cancer

Clinical impact of high serum hepatocyte growth factor in advanced non-small cell lung cancer

https://doi.org/10.18632/oncotarget.17895

Takahiro Tsuji, Yuichi Sakamori, Hiroaki Ozasa, Yoshitaka Yagi, Hitomi Ajimizu, Yuto Yasuda, Tomoko Funazo, Takashi Nomizo, Hironori Yoshida, Hiroki Nagai, Ken Maeno, Tetsuya Oguri, Toyohiro Hirai,  and Young Hak Kim
71805-71816
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In vitro and in vivo cytotoxic activity of human lactoferricin derived antitumor peptide R-DIM-P-LF11-334 on human malignant melanoma

In vitro and in vivo cytotoxic activity of human lactoferricin derived antitumor peptide R-DIM-P-LF11-334 on human malignant melanoma

https://doi.org/10.18632/oncotarget.17823

Sabrina Riedl, Beate Rinner, Helmut Schaider, Bernadette Liegl-Atzwanger, Katharina Meditz, Julia Preishuber-Pflügl, Sarah Grissenberger, Karl Lohner,  and Dagmar Zweytick
71817-71832
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

AG488 as a therapy against gliomas

AG488 as a therapy against gliomas

https://doi.org/10.18632/oncotarget.18284

Jadith Ziegler, Anja Bastian, Megan Lerner, Lora Bailey-Downs, Debra Saunders, Nataliya Smith, Jake Sutton, James D. Battiste, Michael A. Ihnat, Aleem Gangjee,  and Rheal A. Towner
71833-71844
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A peptide antagonist of Prep1-p160 interaction improves ceramide-induced insulin resistance in skeletal muscle cells

A peptide antagonist of Prep1-p160 interaction improves ceramide-induced insulin resistance in skeletal muscle cells

https://doi.org/10.18632/oncotarget.18286

Ilaria Cimmino, Virginia Lorenzo, Francesca Fiory, Nunzianna Doti, Serena Ricci, Serena Cabaro, Antonietta Liotti, Luigi Vitagliano, Michele Longo, Claudia Miele, Pietro Formisano, Francesco Beguinot, Menotti Ruvo,  and Francesco Oriente
71845-71858
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The caudal pedunculopontine tegmental nucleus may be involved in the regulation of skeletal muscle activity by melanocortin-sympathetic pathway: a virally mediated trans-synaptic tracing study in spinally transected transgenic mice

The caudal pedunculopontine tegmental nucleus may be involved in the regulation of skeletal muscle activity by melanocortin-sympathetic pathway: a virally mediated trans-synaptic tracing study in spinally transected transgenic mice

https://doi.org/10.18632/oncotarget.17983

Zhi-Gang He, Bao-Wen Liu, Zhi-Xiao Li, Xue-Bi Tian, San-Guang Liu, Anne Manyande, Ding-Yu Zhang,  and Hong-Bing Xiang
71859-71866
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Loss of Barx1 promotes hepatocellular carcinoma metastasis through up-regulating MGAT5 and MMP9 expression and indicates poor prognosis

Loss of Barx1 promotes hepatocellular carcinoma metastasis through up-regulating MGAT5 and MMP9 expression and indicates poor prognosis

https://doi.org/10.18632/oncotarget.18288

Guodong Wang, Jian Liu, Yi Cai, Jie Chen, Wenbing Xie, Xiangqian Kong, Wenjie Huang, Hao Guo, Xiaodi Zhao, Yuanyuan Lu, Lu Niu, Xiaowei Li, Haijia Zhang, Chao Lei, Zhijie Lei, Jipeng Yin, Hao Hu, Fan Yu, Yongzhan Nie, Limin Xia,  and Kaichun Wu
71867-71880
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LncRNA FENDRR sensitizes doxorubicin-resistance of osteosarcoma cells through down-regulating ABCB1 and ABCC1

LncRNA FENDRR sensitizes doxorubicin-resistance of osteosarcoma cells through down-regulating ABCB1 and ABCC1

https://doi.org/10.18632/oncotarget.17985

Zhu Kun-Peng, Ma Xiao-Long,  and Zhang Chun-Lin
71881-71893
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Identification of a novel YAP–14-3-3ζ negative feedback loop in gastric cancer

Identification of a novel YAP–14-3-3ζ negative feedback loop in gastric cancer

https://doi.org/10.18632/oncotarget.18011

Bin Zhang, Aihua Gong, Hui Shi, Qingli Bie, Zhaofeng Liang, Peipei Wu, Fei Mao, Hui Qian,  and Wenrong Xu
71894-71910
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Endoplasmic reticulum chaperone prolyl 4-hydroxylase, beta polypeptide (P4HB) promotes malignant phenotypes in glioma via MAPK signaling

Endoplasmic reticulum chaperone prolyl 4-hydroxylase, beta polypeptide (P4HB) promotes malignant phenotypes in glioma via MAPK signaling

https://doi.org/10.18632/oncotarget.18026

Stella Sun, Karrie M.Y. Kiang, Amy S.W. Ho, Derek Lee, Ming-Wai Poon, Fei-Fan Xu, Jenny K.S. Pu, Amanda N.C. Kan, Nikki P.Y. Lee, Xiao-Bing Liu, Kwan Man, Philip J.R. Day, Wai-Man Lui, Ching-Fai Fung,  and Gilberto K.K. Leung
71911-71923
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Analysis of miRNA expression profile induced by short term starvation in breast cancer cells treated with doxorubicin

Analysis of miRNA expression profile induced by short term starvation in breast cancer cells treated with doxorubicin

https://doi.org/10.18632/oncotarget.18028

Sergio Rizzo, Antonina Cangemi, Antonio Galvano, Daniele Fanale, Silvio Buscemi, Marcello Ciaccio, Antonio Russo, Sergio Castorina,  and Viviana Bazan
71924-71932
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Transcriptional factor OCT4 promotes esophageal cancer metastasis by inducing epithelial-mesenchymal transition through VEGF-C/VEGFR-3 signaling pathway

Transcriptional factor OCT4 promotes esophageal cancer metastasis by inducing epithelial-mesenchymal transition through VEGF-C/VEGFR-3 signaling pathway

https://doi.org/10.18632/oncotarget.18035

Chunguang Li, Maoling Zhu, Xiaoli Lou, Chunying Liu, Hezhong Chen, Xuejing Lin, Weidan Ji, Zhigang Li,  and Changqing Su
71933-71945
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Diagnosis of Pneumocystis jirovecii pneumonia with serum cell-free DNA in non-HIV-infected immunocompromised patients

Diagnosis of Pneumocystis jirovecii pneumonia with serum cell-free DNA in non-HIV-infected immunocompromised patients

https://doi.org/10.18632/oncotarget.18037

Dong Wang, Yang Hu, Ting Li, Heng-Mo Rong,  and Zhao-Hui Tong
71946-71953
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Up-regulation of CIT promotes the growth of colon cancer cells

Up-regulation of CIT promotes the growth of colon cancer cells

https://doi.org/10.18632/oncotarget.18615

Zehua Wu, Xiangying Zhu, Wendi Xu, Yu Zhang, Lin Chen, Fabo Qiu, Binyuan Zhang, Liqun Wu, Zhihai Peng,  and Huamei Tang
71954-71964
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Myeloid-specific genetic ablation of ATP-binding cassette transporter ABCA1 is protective against cancer

Myeloid-specific genetic ablation of ATP-binding cassette transporter ABCA1 is protective against cancer

https://doi.org/10.18632/oncotarget.18666

Maryam Zamanian-Daryoush, Daniel J. Lindner, Joseph A. DiDonato, Mathew Wagner, Jennifer Buffa, Pat Rayman, John S. Parks, Marit Westerterp, Alan R. Tall,  and Stanley L. Hazen
71965-71980
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Cell lines generated from a chronic lymphocytic leukemia mouse model exhibit constitutive Btk and Akt signaling

Cell lines generated from a chronic lymphocytic leukemia mouse model exhibit constitutive Btk and Akt signaling

https://doi.org/10.18632/oncotarget.18234

Simar Pal Singh, Saravanan Y. Pillai, Marjolein J.W. de Bruijn, Ralph Stadhouders, Odilia B.J. Corneth, Henk Jan van den Ham, Alice Muggen, Wilfred van IJcken, Erik Slinger, Annemieke Kuil, Marcel Spaargaren, Arnon P. Kater, Anton W. Langerak,  and Rudi W. Hendriks
71981-71995
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Macrophages are targets of retinoic acid signaling during the wound-healing process after thulium laser resection of the prostate

Macrophages are targets of retinoic acid signaling during the wound-healing process after thulium laser resection of the prostate

https://doi.org/10.18632/oncotarget.18238

Dian-Jun Yu, Xing-Jie Wang, Yun-Feng Shi, Chen-Yi Jiang, Rui-Zhe Zhao, Yi-Ping Zhu, Li Chen, Yuan-Qing Yang, Xiao-Wen Sun,  and Shu-Jie Xia
71996-72007
Abstract  |  PDF  |  HTML  |  Order a Reprint

Dual effects of constitutively active androgen receptor and full-length androgen receptor for N-cadherin regulation in prostate cancer

Dual effects of constitutively active androgen receptor and full-length androgen receptor for N-cadherin regulation in prostate cancer

https://doi.org/10.18632/oncotarget.18270

Félicie Cottard, Pauline Ould Madi-Berthélémy, Eva Erdmann, Frédérique Schaff-Wendling, Céline Keime, Tao Ye, Jean-Emmanuel Kurtz,  and Jocelyn Céraline
72008-72020
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MARCKS promotes invasion and is associated with biochemical recurrence in prostate cancer

MARCKS promotes invasion and is associated with biochemical recurrence in prostate cancer

https://doi.org/10.18632/oncotarget.18894

Emma Dorris, Amanda O’Neill, Karen Hanrahan, Ann Treacy,  and R. William Watson
72021-72030
Abstract  |  PDF  |  HTML  |  Order a Reprint

Prognostic significance of clinicopathological factors in early breast cancer: 20 years of follow-up in a single-center analysis

Prognostic significance of clinicopathological factors in early breast cancer: 20 years of follow-up in a single-center analysis

https://doi.org/10.18632/oncotarget.18526

Valentina Cocciolone, Katia Cannita, Maria Letizia Calandrella, Enrico Ricevuto, Paola Lanfiuti Baldi, Tina Sidoni, Azzurra Irelli, Stefania Paradisi, Laura Pizzorno, Valter Resta, Alberto Bafile, Edoardo Alesse, Alessandra Tessitore,  and Corrado Ficorella
72031-72043
Abstract  |  PDF  |  HTML  |  Order a Reprint

Clinical study on the relationship between hepatitis B virus infection and risk of breast cancer: a large sized case-control and single center study in southwest of China

Clinical study on the relationship between hepatitis B virus infection and risk of breast cancer: a large sized case-control and single center study in southwest of China

https://doi.org/10.18632/oncotarget.19132

Lin-Jie Lu, Vishnu Prasad Adhikari, Chun-Xia Zhao, He Wu, Wei Dai, Xin Li, Hong-Yuan Li, Guo-Sheng Ren, Kai-Nan Wu,  and Ling-Quan Kong
72044-72053
Abstract  |  PDF  |  HTML  |  Order a Reprint

Direct comparison study of DNA methylation markers in EpCAM-positive circulating tumour cells, corresponding circulating tumour DNA, and paired primary tumours in breast cancer

Direct comparison study of DNA methylation markers in EpCAM-positive circulating tumour cells, corresponding circulating tumour DNA, and paired primary tumours in breast cancer

https://doi.org/10.18632/oncotarget.18679

Maria Chimonidou, Areti Strati, Nikos Malamos, Sophia Kouneli, Vassilis Georgoulias,  and Evi Lianidou
72054-72068
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Xuefu zhuyu decoction improves cognitive impairment in experimental traumatic brain injury via synaptic regulation

Xuefu zhuyu decoction improves cognitive impairment in experimental traumatic brain injury via synaptic regulation

https://doi.org/10.18632/oncotarget.18895

Jing Zhou, Tao Liu, Hanjin Cui, Rong Fan, Chunhu Zhang, Weijun Peng, Ali Yang, Lin Zhu, Yang Wang,  and Tao Tang
72069-72081
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Genome-wide functional analysis on the molecular mechanism of specifically biosynthesized fluorescence Eu complex

Genome-wide functional analysis on the molecular mechanism of specifically biosynthesized fluorescence Eu complex

https://doi.org/10.18632/oncotarget.18914

Jing Ye, Xiawei Dong, Xuerui Jiang, Hui Jiang, Chen-Zhong Li,  and Xuemei Wang
72082-72095
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Expression of protein kinase C gamma promotes cell migration in colon cancer

Expression of protein kinase C gamma promotes cell migration in colon cancer

https://doi.org/10.18632/oncotarget.18916

Catríona M. Dowling, Sheri L. Hayes, James J. Phelan, Mary Clare Cathcart, Stephen P. Finn, Brian Mehigan, Paul McCormick, John C. Coffey, Jacintha O’Sullivan,  and Patrick A. Kiely
72096-72107
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The integrative clinical impact of tumor-infiltrating T lymphocytes and NK cells in relation to B lymphocyte and plasma cell density in esophageal and gastric adenocarcinoma

The integrative clinical impact of tumor-infiltrating T lymphocytes and NK cells in relation to B lymphocyte and plasma cell density in esophageal and gastric adenocarcinoma

https://doi.org/10.18632/oncotarget.19437

Maria C. Svensson, Carl Fredrik Warfvinge, Richard Fristedt, Charlotta Hedner, David Borg, Jakob Eberhard, Patrick Micke, Björn Nodin, Karin Leandersson,  and Karin Jirström
72108-72126
Abstract  |  PDF  |  HTML  |  Order a Reprint

Visualization and quantitation of epidermal growth factor receptor homodimerization and activation with a proximity ligation assay

Visualization and quantitation of epidermal growth factor receptor homodimerization and activation with a proximity ligation assay

https://doi.org/10.18632/oncotarget.19552

Keiichi Ota, Taishi Harada, Kohei Otsubo, Akiko Fujii, Yuko Tsuchiya, Kentaro Tanaka, Isamu Okamoto,  and Yoichi Nakanishi
72127-72132
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Targeting of PHOX2B expression allows the identification of drugs effective in counteracting neuroblastoma cell growth

Targeting of PHOX2B expression allows the identification of drugs effective in counteracting neuroblastoma cell growth

https://doi.org/10.18632/oncotarget.19922

Eleonora Di Zanni, Giovanna Bianchi, Roberto Ravazzolo, Lizzia Raffaghello, Isabella Ceccherini,  and Tiziana Bachetti
72133-72146
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Drug repositioning of mevalonate pathway inhibitors as antitumor agents for ovarian cancer

Drug repositioning of mevalonate pathway inhibitors as antitumor agents for ovarian cancer

https://doi.org/10.18632/oncotarget.20046

Yusuke Kobayashi, Hiroyasu Kashima, Yohan Suryo Rahmanto, Kouji Banno, Yu Yu, Yusuke Matoba, Keiko Watanabe, Moito Iijima, Takashi Takeda, Haruko Kunitomi, Miho Iida, Masataka Adachi, Kanako Nakamura, Kosuke Tsuji, Kenta Masuda, Hiroyuki Nomura, Eiichiro Tominaga,  and Daisuke Aoki
72147-72156
Abstract  |  PDF  |  HTML  |  Order a Reprint

The crucial role of SRPK1 in IGF-1-induced EMT of human gastric cancer

The crucial role of SRPK1 in IGF-1-induced EMT of human gastric cancer

https://doi.org/10.18632/oncotarget.20048

Hong Wang, Chunlei Wang, Wenling Tian,  and Yanfen Yao
72157-72166
Abstract  |  PDF  |  HTML  |  Order a Reprint

Small-molecule inhibitors of PD-1/PD-L1 immune checkpoint alleviate the PD-L1-induced exhaustion of T-cells

Small-molecule inhibitors of PD-1/PD-L1 immune checkpoint alleviate the PD-L1-induced exhaustion of T-cells

https://doi.org/10.18632/oncotarget.20050

Lukasz Skalniak, Krzysztof M. Zak, Katarzyna Guzik, Katarzyna Magiera, Bogdan Musielak, Magdalena Pachota, Bozena Szelazek, Justyna Kocik, Przemyslaw Grudnik, Marcin Tomala, Sylwia Krzanik, Krzysztof Pyrc, Alexander Dömling, Grzegorz Dubin,  and Tad A. Holak
72167-72181
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Discovery and validation of the tumor-suppressive function of long noncoding RNA PANDA in human diffuse large B-cell lymphoma through the inactivation of MAPK/ERK signaling pathway

Discovery and validation of the tumor-suppressive function of long noncoding RNA PANDA in human diffuse large B-cell lymphoma through the inactivation of MAPK/ERK signaling pathway

https://doi.org/10.18632/oncotarget.20053

Yingjun Wang, Mingzhi Zhang, Huanan Xu, Yifei Wang, Zhaoming Li, Yu Chang, Xinhuan Wang, Xiaorui Fu, Zhiyuan Zhou, Siyuan Yang, Bei Wang,  and Yufeng Shang
72182-72196
Abstract  |  PDF  |  HTML  |  Order a Reprint

MMP16 promotes tumor metastasis and indicates poor prognosis in hepatocellular carcinoma

MMP16 promotes tumor metastasis and indicates poor prognosis in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.20060

Zhenghai Shen, Xing Wang, Xiaotian Yu, Yun Zhang,  and Lei Qin
72197-72204
Abstract  |  PDF  |  HTML  |  Order a Reprint

Induction of GD3/α1-adrenergic receptor/transglutaminase 2-mediated erythroid differentiation in chronic myelogenous leukemic K562 cells

Induction of GD3/α1-adrenergic receptor/transglutaminase 2-mediated erythroid differentiation in chronic myelogenous leukemic K562 cells

https://doi.org/10.18632/oncotarget.20080

Sun-Hyung Ha, Sung-Koo Kang, Hyunju Choi, Choong-Hwan Kwak, Fukushi Abekura, Jun-Young Park, Kyung-Min Kwon, Hyeun-Wook Chang, Young-Choon Lee, Ki-Tae Ha, Bo Kyeng Hou, Tae-Wook Chung,  and Cheorl-Ho Kim
72205-72219
Abstract  |  PDF  |  HTML  |  Order a Reprint

Downregulation of circulating exosomal miR-638 predicts poor prognosis in colon cancer patients

Downregulation of circulating exosomal miR-638 predicts poor prognosis in colon cancer patients

https://doi.org/10.18632/oncotarget.19689

Shushan Yan, Guangwang Dang, Xiaoyu Zhang, Chengwen Jin, Lang Qin, Yugang Wang, Min Shi, Haijin Huang,  and Quanhong Duan
72220-72226
Abstract  |  PDF  |  HTML  |  Order a Reprint

Common genetic variant rs3802842 in 11q23 contributes to colorectal cancer risk in Chinese population

Common genetic variant rs3802842 in 11q23 contributes to colorectal cancer risk in Chinese population

https://doi.org/10.18632/oncotarget.19702

Chunze Zhang, Xichuan Li, Weihua Zhang, Yijia Wang, Guanwei Fan, Wenhong Wang, Shuo Chen, Hai Qin,  and Xipeng Zhang
72227-72234
Abstract  |  PDF  |  HTML  |  Order a Reprint

TLE1 inhibits anoikis and promotes tumorigenicity in human lung cancer cells through ZEB1-mediated E-cadherin repression

TLE1 inhibits anoikis and promotes tumorigenicity in human lung cancer cells through ZEB1-mediated E-cadherin repression

https://doi.org/10.18632/oncotarget.19703

Xin Yao, Tri Pham, Brandi Temple, Selena Gray, Cornita Cannon, Camry Hardy, Kamari Fletcher, Shubha Kale Ireland, Ahamed Hossain, Renwei Chen, Asim B. Abdel-Mageed,  and Hector Biliran
72235-72249
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

High expression of dedicator of cytokinesis 1 (DOCK1) confers poor prognosis in acute myeloid leukemia

High expression of dedicator of cytokinesis 1 (DOCK1) confers poor prognosis in acute myeloid leukemia

https://doi.org/10.18632/oncotarget.19706

Sze-Hwei Lee, Yu-Chiao Chiu, Yi-Hung Li, Chien-Chin Lin, Hsin-An Hou, Wen-Chien Chou,  and Hwei-Fang Tien
72250-72259
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

[10]-gingerol induces apoptosis and inhibits metastatic dissemination of triple negative breast cancer in vivo

[10]-gingerol induces apoptosis and inhibits metastatic dissemination of triple negative breast cancer in vivo

https://doi.org/10.18632/oncotarget.20139

Ana Carolina B.M. Martin, Angelina M. Fuzer, Amanda B. Becceneri, James Almada da Silva, Rebeka Tomasin, Delphine Denoyer, Soo-Hyun Kim, Katherine A. McIntyre, Helen B. Pearson, Belinda Yeo, Aadya Nagpal, Xiawei Ling, Heloisa S. Selistre-de-Araújo, Paulo Cézar Vieira, Marcia R. Cominetti,  and Normand Pouliot
72260-72271
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The overexpression of salivary cytokeratins as potential diagnostic biomarkers in head and neck squamous cell carcinomas

The overexpression of salivary cytokeratins as potential diagnostic biomarkers in head and neck squamous cell carcinomas

https://doi.org/10.18632/oncotarget.19731

Kai Dun Tang, Liz Kenny, Chris Perry, Ian Frazer,  and Chamindie Punyadeera
72272-72280
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Proteasome inhibitors prevent bi-directional HER2/estrogen-receptor cross-talk leading to cell death in endocrine and lapatinib-resistant HER2+/ER+ breast cancer cells

Proteasome inhibitors prevent bi-directional HER2/estrogen-receptor cross-talk leading to cell death in endocrine and lapatinib-resistant HER2+/ER+ breast cancer cells

https://doi.org/10.18632/oncotarget.20261

Sonja Thaler, Marcus Schmidt, Sven Roßwag, Gitta Thiede, Arno Schad,  and Jonathan P. Sleeman
72281-72301
Abstract  |  PDF  |  HTML  |  Order a Reprint

The sirtuin 6 prevents angiotensin II-mediated myocardial fibrosis and injury by targeting AMPK-ACE2 signaling

The sirtuin 6 prevents angiotensin II-mediated myocardial fibrosis and injury by targeting AMPK-ACE2 signaling

https://doi.org/10.18632/oncotarget.20305

Zhen-Zhou Zhang, Yu-Wen Cheng, Hai-Yan Jin, Qing Chang, Qian-Hui Shang, Ying-Le Xu, Lin-Xi Chen, Ran Xu, Bei Song,  and Jiu-Chang Zhong
72302-72314
Abstract  |  PDF  |  HTML  |  Order a Reprint

Postoperative course and prognostic value of circulating angiogenic cytokines after pancreatic cancer resection

Postoperative course and prognostic value of circulating angiogenic cytokines after pancreatic cancer resection

https://doi.org/10.18632/oncotarget.20315

Cui Yang, Ulrich Bork, Sebastian Schölch, Yakup Kulu, Lars Kaderali, Uta L. Bolstorff, Christoph Kahlert, Jürgen Weitz, Nuh N. Rahbari,  and Christoph Reissfelder
72315-72323
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Downregulation of type 3 inositol (1,4,5)-trisphosphate receptor decreases breast cancer cell migration through an oscillatory Ca2+ signal

Downregulation of type 3 inositol (1,4,5)-trisphosphate receptor decreases breast cancer cell migration through an oscillatory Ca2+ signal

https://doi.org/10.18632/oncotarget.20327

Abdallah Mound, Alexia Vautrin-Glabik, Arthur Foulon, Béatrice Botia, Frédéric Hague, Jan B. Parys, Halima Ouadid-Ahidouch,  and Lise Rodat-Despoix
72324-72341
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Immunohistochemical biomarkers and volumetric parameters for predicting radiotherapy-based outcomes in patients with p16-negative pharyngeal cancer

Immunohistochemical biomarkers and volumetric parameters for predicting radiotherapy-based outcomes in patients with p16-negative pharyngeal cancer

https://doi.org/10.18632/oncotarget.20374

Rui-Yun Chen, Ying-Chun Lin, Shang-Wen Chen, Tze-Yi Lin, Te-Chun Hsieh, Kuo-Yang Yen, Ji-An Liang, Shih-Neng Yang, Yao-Ching Wang, Ya-Huey Chen, Shu-Fen Chiang,  and Chia-Hung Kao
72342-72351
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Acquired somatic TP53 or PIK3CA mutations are potential predictors of when polyps evolve into colorectal cancer

Acquired somatic TP53 or PIK3CA mutations are potential predictors of when polyps evolve into colorectal cancer

https://doi.org/10.18632/oncotarget.20376

Pi-Yueh Chang, Jinn-Shiun Chen, Shih-Cheng Chang, Mei-Chia Wang, Nai-Chung Chang, Ying-Hao Wen, Wen-Sy Tsai, Wei-Hsiu Liu, Hsiu-Ling Liu,  and Jang-Jih Lu
72352-72362
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Imprinting disorder in donor cells is detrimental to the development of cloned embryos in pigs

Imprinting disorder in donor cells is detrimental to the development of cloned embryos in pigs

https://doi.org/10.18632/oncotarget.20390

Xuexiong Song, Fangzheng Li, Zhongling Jiang, Yueping Sun, Huatao Li, Shansong Gao, Liping Zhang, Binghua Xue, Guimin Zhao, Jingyu Li, Zhonghua Liu, Hongbin He,  and Yanjun Huan
72363-72374
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Association between MPHOSPH6 gene polymorphisms and IgA nephropathy risk in a Chinese Han population

Association between MPHOSPH6 gene polymorphisms and IgA nephropathy risk in a Chinese Han population

https://doi.org/10.18632/oncotarget.19758

Xiaohong Yang, Yin Zhang, Wenning Li, Yan Su, Dan Niu, Yanni Wang, Haiyang Huang, Hui Han, Daofa Zhang, Maowei Xie, Huiluan Su, Wentan Xu,  and Jiali Wei
72375-72380
Abstract  |  PDF  |  HTML  |  Order a Reprint

Variants of GSK3β and SFRP4 genes in Wnt signaling were not associated with osteonecrosis of the femoral head

Variants of GSK3β and SFRP4 genes in Wnt signaling were not associated with osteonecrosis of the femoral head

https://doi.org/10.18632/oncotarget.20393

Yang Song, Zhenwu Du, Qiwei Yang, Ming Ren, Qingyu Wang, Gaoyang Chen, Haiyue Zhao, Zhaoyan Li,  and Guizhen Zhang
72381-72388
Abstract  |  PDF  |  HTML  |  Order a Reprint

Nomogram for prediction of level 2 axillary lymph node metastasis in proven level 1 node-positive breast cancer patients

Nomogram for prediction of level 2 axillary lymph node metastasis in proven level 1 node-positive breast cancer patients

https://doi.org/10.18632/oncotarget.20395

Yanlin Jiang, Hong Xu, Hao Zhang, Xunyan Ou, Zhen Xu, Liping Ai, Lisha Sun,  and Caigang Liu
72389-72399
Abstract  |  PDF  |  HTML  |  Order a Reprint

MicroRNA-16-5p overexpression suppresses proliferation and invasion as well as triggers apoptosis by targeting VEGFA expression in breast carcinoma

MicroRNA-16-5p overexpression suppresses proliferation and invasion as well as triggers apoptosis by targeting VEGFA expression in breast carcinoma

https://doi.org/10.18632/oncotarget.20398

Yunhui Qu, Hongtao Liu, Xinquan Lv, Yuqiong Liu, Xiaojuan Wang, Min Zhang, Xiaqing Zhang, Yuenan Li, Qianqian Lou, Shenglei Li,  and Huixiang Li
72400-72410
Abstract  |  PDF  |  HTML  |  Order a Reprint

Efficient cell death induction in human glioblastoma cells by photodynamic treatment with Tetrahydroporphyrin-Tetratosylat (THPTS) and ionizing irradiation

Efficient cell death induction in human glioblastoma cells by photodynamic treatment with Tetrahydroporphyrin-Tetratosylat (THPTS) and ionizing irradiation

https://doi.org/10.18632/oncotarget.20403

Peter Hambsch, Yury P. Istomin, Dimitri A. Tzerkovsky, Ina Patties, Jochen Neuhaus, Rolf-Dieter Kortmann, Stanislav Schastak,  and Annegret Glasow
72411-72423
Abstract  |  PDF  |  HTML  |  Order a Reprint

Functional compatibility between Purkinje cell axon branches and their target neurons in the cerebellum

Functional compatibility between Purkinje cell axon branches and their target neurons in the cerebellum

https://doi.org/10.18632/oncotarget.19770

Zhilai Yang, Na Chen, Rongjing Ge, Hao Qian,  and Jin-Hui Wang
72424-72437
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Evaluation of cytology versus human papillomavirus-based cervical cancer screening algorithms in Bhutan

Evaluation of cytology versus human papillomavirus-based cervical cancer screening algorithms in Bhutan

https://doi.org/10.18632/oncotarget.19783

Ugyen Tshomo, Silvia Franceschi, Tshokey Tshokey, Tashi Tobgay, Iacopo Baussano, Vanessa Tenet, Daniëlle A.M. Heideman, Peter J.F. Snijders,  and Gary M. Clifford
72438-72446
Abstract  |  PDF  |  HTML  |  Order a Reprint

Effect of weekly or daily dosing regimen of Gefitinib in mouse models of lung cancer

Effect of weekly or daily dosing regimen of Gefitinib in mouse models of lung cancer

https://doi.org/10.18632/oncotarget.19785

Qi Zhang, Ruichao Li, Xu Chen, Sang Beom Lee, Jing Pan, Donghai Xiong, Jiaqi Hu, Mark Steven Miller, Eva Szabo, Ronald A. Lubet, Yian Wang,  and Ming You
72447-72456
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Advanced nasopharyngeal carcinoma: pre-treatment prediction of progression based on multi-parametric MRI radiomics

Advanced nasopharyngeal carcinoma: pre-treatment prediction of progression based on multi-parametric MRI radiomics

https://doi.org/10.18632/oncotarget.19799

Bin Zhang, Fusheng Ouyang, Dongsheng Gu, Yuhao Dong, Lu Zhang, Xiaokai Mo, Wenhui Huang,  and Shuixing Zhang
72457-72465
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The significance of ENAH in carcinogenesis and prognosis in gastric cancer

The significance of ENAH in carcinogenesis and prognosis in gastric cancer

https://doi.org/10.18632/oncotarget.19801

Dan-Dan Wang, Qun Jin, Lei-Lei Wang, Shu-Fang Han, Yi-Bing Chen, Guo-Dong Sun, Shi-Fei Sun, Shu-Wang Sun, Tao Wang, Fan-Jie Liu, Ping Wang,  and Bin Shi
72466-72479
Abstract  |  PDF  |  HTML  |  Order a Reprint

Progesterone receptor membrane component 1 is phosphorylated upon progestin treatment in breast cancer cells

Progesterone receptor membrane component 1 is phosphorylated upon progestin treatment in breast cancer cells

https://doi.org/10.18632/oncotarget.19819

Marina Willibald, Giuliano Bayer, Vanessa Stahlhut, Gereon Poschmann, Kai Stühler, Berthold Gierke, Michael Pawlak, Harald Seeger, Alfred O. Mueck, Dieter Niederacher, Tanja Fehm,  and Hans Neubauer
72480-72493
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Epidermal growth factor receptor activity is elevated in glioma cancer stem cells and is required to maintain chemotherapy and radiation resistance

Epidermal growth factor receptor activity is elevated in glioma cancer stem cells and is required to maintain chemotherapy and radiation resistance

https://doi.org/10.18632/oncotarget.19868

Lisa Y. Pang, Lauren Saunders,  and David J. Argyle
72494-72512
Abstract  |  PDF  |  HTML  |  Order a Reprint

Modulating BAP1 expression affects ROS homeostasis, cell motility and mitochondrial function

Modulating BAP1 expression affects ROS homeostasis, cell motility and mitochondrial function

https://doi.org/10.18632/oncotarget.19872

Lucie Hebert, Dorine Bellanger, Chloé Guillas, Antoine Campagne, Florent Dingli, Damarys Loew, Alice Fievet, Virginie Jacquemin, Tatiana Popova, Didier Jean, Fatima Mechta-Grigoriou, Raphaël Margueron,  and Marc-Henri Stern
72513-72527
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Chronic high dose of captopril induces depressive-like behaviors in mice: possible mechanism of regulatory T cell in depression

Chronic high dose of captopril induces depressive-like behaviors in mice: possible mechanism of regulatory T cell in depression

https://doi.org/10.18632/oncotarget.19879

Hyun-Sun Park, Arum Han, Hye-Lim Yeo, Min-Jung Park, Min-Jung You, Hyun Jin Choi, Chang-Won Hong, Sang-Hyuk Lee, Seung Hyun Kim, Borah Kim,  and Min-Soo Kwon
72528-72543
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Targeting the cancer stem cell marker, aldehyde dehydrogenase 1, to circumvent cisplatin resistance in NSCLC

Targeting the cancer stem cell marker, aldehyde dehydrogenase 1, to circumvent cisplatin resistance in NSCLC

https://doi.org/10.18632/oncotarget.19881

Lauren MacDonagh, Michael F. Gallagher, Brendan Ffrench, Claudia Gasch, Eamon Breen, Steven G. Gray, Siobhan Nicholson, Niamh Leonard, Ronan Ryan, Vincent Young, John J. O’Leary, Sinead Cuffe, Stephen P. Finn, Kenneth J. O’Byrne,  and Martin P. Barr
72544-72563
Abstract  |  PDF  |  HTML  |  Order a Reprint

Human papillomavirus dysregulates the cellular apparatus controlling the methylation status of H3K27 in different human cancers to consistently alter gene expression regardless of tissue of origin

Human papillomavirus dysregulates the cellular apparatus controlling the methylation status of H3K27 in different human cancers to consistently alter gene expression regardless of tissue of origin

https://doi.org/10.18632/oncotarget.19885

Steven F. Gameiro, Bart Kolendowski, Ali Zhang, John W. Barrett, Anthony C. Nichols, Joe Torchia,  and Joe S. Mymryk
72564-72576
Abstract  |  PDF  |  HTML  |  Order a Reprint

The recurrence risk of neural tube defects (NTDs) in a population with high prevalence of NTDs in northern China

The recurrence risk of neural tube defects (NTDs) in a population with high prevalence of NTDs in northern China

https://doi.org/10.18632/oncotarget.19890

Jufen Liu, Zhiwen Li, Nicholas D.E. Greene, Hongtian Li,  and Aiguo Ren
72577-72583
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Extracellular sphingomyelinase activity impairs TNF-α-induced endothelial cell death via ADAM17 activation and TNF receptor 1 shedding

Extracellular sphingomyelinase activity impairs TNF-α-induced endothelial cell death via ADAM17 activation and TNF receptor 1 shedding

https://doi.org/10.18632/oncotarget.19983

Anselm Sommer, Marie Düppe, Lena Baumecker, Felix Kordowski, Joscha Büch, Johaiber Fuchslocher Chico, Jürgen Fritsch, Stefan Schütze, Dieter Adam, Maria Sperrhacke, Sucharit Bhakdi,  and Karina Reiss
72584-72596
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

M2 macrophages are more resistant than M1 macrophages following radiation therapy in the context of glioblastoma

M2 macrophages are more resistant than M1 macrophages following radiation therapy in the context of glioblastoma

https://doi.org/10.18632/oncotarget.19994

Marine M. Leblond, Elodie A. Pérès, Charly Helaine, Aurélie N. Gérault, Damien Moulin, Clément Anfray, Didier Divoux, Edwige Petit,  and Myriam Bernaudin Samuel Valable
72597-72612
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Transarterial chemoembolization (TACE) with degradable starch microspheres (DSM) in hepatocellular carcinoma (HCC): multi-center results on safety and efficacy

Transarterial chemoembolization (TACE) with degradable starch microspheres (DSM) in hepatocellular carcinoma (HCC): multi-center results on safety and efficacy

https://doi.org/10.18632/oncotarget.19997

Andreas Schicho, Philippe L. Pereira, Michael Haimerl, Christoph Niessen, Katharina Michalik, Lukas P. Beyer, Christian Stroszczynski,  and Philipp Wiggermann
72613-72620
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Circulating tumor DNA detection in head and neck cancer: evaluation of two different detection approaches

Circulating tumor DNA detection in head and neck cancer: evaluation of two different detection approaches

https://doi.org/10.18632/oncotarget.20004

Sandra Perdomo, Patrice H. Avogbe, Matthieu Foll, Behnoush Abedi-Ardekani, Violeta Lescher Facciolla, Devasena Anantharaman, Priscilia Chopard, Florence Le Calvez-Kelm, Marta Vilensky, Jerry Polesel, Ivana Holcatova, Lorenzo Simonato, Cristina Canova, Pagona Lagiou, James D. McKay,  and Paul Brennan
72621-72632
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

RPN2 promotes colorectal cancer cell proliferation through modulating the glycosylation status of EGFR

RPN2 promotes colorectal cancer cell proliferation through modulating the glycosylation status of EGFR

https://doi.org/10.18632/oncotarget.20005

Haiping Li, Al-Japairai K, Yong Tao, Zheng Xiang,  and Zheng Xiang
72633-72651
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Ubenimex suppresses Pim-3 kinase expression by targeting CD13 to reverse MDR in HCC cells

Ubenimex suppresses Pim-3 kinase expression by targeting CD13 to reverse MDR in HCC cells

https://doi.org/10.18632/oncotarget.20194

Qie Guo, Zhong-Guo Sui, Wen Xu, Xiang-Hua Quan, Jia-Lin Sun, Xiao Li, Hong-Yan Ji,  and Fan-Bo Jing
72652-72665
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Binase treatment increases interferon sensitivity and apoptosis in SiHa cervical carcinoma cells by downregulating E6 and E7 human papilloma virus oncoproteins

Binase treatment increases interferon sensitivity and apoptosis in SiHa cervical carcinoma cells by downregulating E6 and E7 human papilloma virus oncoproteins

https://doi.org/10.18632/oncotarget.20199

Vladimir A. Mitkevich, Ksenia M. Burnysheva, Irina Yu Petrushanko, Alexei A. Adzhubei, Alexey A. Schulga, Peter M. Chumakov,  and Alexander A. Makarov
72666-72675
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Inhibiting PHD2 in bone marrow mesenchymal stem cells via lentiviral vector-mediated RNA interference facilitates the repair of periodontal tissue defects in SD rats

Inhibiting PHD2 in bone marrow mesenchymal stem cells via lentiviral vector-mediated RNA interference facilitates the repair of periodontal tissue defects in SD rats

https://doi.org/10.18632/oncotarget.20243

Changxing Chen, Houxuan Li, Jun Jiang, Qian Zhang,  and Fuhua Yan
72676-72699
Abstract  |  PDF  |  HTML  |  Order a Reprint

Comparison of twelve single-drug regimens for the treatment of type 2 diabetes mellitus

Comparison of twelve single-drug regimens for the treatment of type 2 diabetes mellitus

https://doi.org/10.18632/oncotarget.20282

Shao-Lian Wang, Wen-Bin Dong, Xiao-Lin Dong, Wen-Min Zhu, Fang-Fang Wang, Fang Han,  and Xin Yan
72700-72713
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The influence of two functional genetic variants of GRK5 on tau phosphorylation and their association with Alzheimer’s disease risk

The influence of two functional genetic variants of GRK5 on tau phosphorylation and their association with Alzheimer’s disease risk

https://doi.org/10.18632/oncotarget.20283

Yuan Zhang, Jianghao Zhao, Mingkang Yin, Yujie Cai, Shengyuan Liu, Yan Wang, Xingliang Zhang, Hao Cao, Ting Chen, Pengru Huang, Hui Mai, Zhou Liu, Hua Tao, Bin Zhao,  and Lili Cui
72714-72726
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Combination treatment of ergosterol followed by amphotericin B induces necrotic cell death in human hepatocellular carcinoma cells

Combination treatment of ergosterol followed by amphotericin B induces necrotic cell death in human hepatocellular carcinoma cells

https://doi.org/10.18632/oncotarget.20285

Yu-Chun Lin, Bao-Hong Lee, Jassey Alagie,  and Ching-Hua Su
72727-72738
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Alpha lipoic acid attenuates radiation-induced oral mucositis in rats

Alpha lipoic acid attenuates radiation-induced oral mucositis in rats

https://doi.org/10.18632/oncotarget.20286

Jin Hyun Kim, Myeong Hee Jung, Jin Pyeong Kim, Hyun-Jung Kim, Jung Hwa Jung, Jong Ryeal Hahm, Ki Mun Kang, Bae-Kwon Jeong,  and Seung Hoon Woo
72739-72747
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MicroRNA-134 plasma levels before and after treatment with valproic acid for epilepsy patients

MicroRNA-134 plasma levels before and after treatment with valproic acid for epilepsy patients

https://doi.org/10.18632/oncotarget.20292

Xiaofeng Wang, Yifeng Luo, Shuangxi Liu, Liming Tan, Sanhu Wang,  and Rongyong Man
72748-72754
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Sensitive detection of PD-L1 expression on circulating epithelial tumor cells (CETCs) could be a potential biomarker to select patients for treatment with PD-1/PD-L1 inhibitors in early and metastatic solid tumors

Sensitive detection of PD-L1 expression on circulating epithelial tumor cells (CETCs) could be a potential biomarker to select patients for treatment with PD-1/PD-L1 inhibitors in early and metastatic solid tumors

https://doi.org/10.18632/oncotarget.20346

Dorothea Sonja Schott, Monika Pizon, Ulrich Pachmann,  and Katharina Pachmann
72755-72772
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Mono-ADP-ribosylation of histone 3 at arginine-117 promotes proliferation through its interaction with P300

Mono-ADP-ribosylation of histone 3 at arginine-117 promotes proliferation through its interaction with P300

https://doi.org/10.18632/oncotarget.20347

Feng Ling, Yi Tang, Ming Li, Qing-Shu Li, Xian Li, Lian Yang, Wei Zhao, Cong-Cong Jin, Zhen Zeng, Chang Liu, Cheng-Fang Wu, Wen-Wen Chen, Xiao Lin, Ya-Lan Wang,  and Michael D. Threadgill
72773-72787
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miR-150 enhances apoptotic and anti-tumor effects of paclitaxel in paclitaxel-resistant ovarian cancer cells by targeting Notch3

miR-150 enhances apoptotic and anti-tumor effects of paclitaxel in paclitaxel-resistant ovarian cancer cells by targeting Notch3

https://doi.org/10.18632/oncotarget.20348

Tae Hoen Kim, Ju-Yeon Jeong, Ju-Yeon Park, Se-Wha Kim, Jin Hyung Heo, Haeyoun Kang, Gwangil Kim,  and Hee Jung An
72788-72800
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The effect of MVK-MMAB variants, their haplotypes and G×E interactions on serum lipid levels and the risk of coronary heart disease and ischemic stroke

The effect of MVK-MMAB variants, their haplotypes and G×E interactions on serum lipid levels and the risk of coronary heart disease and ischemic stroke

https://doi.org/10.18632/oncotarget.20349

Liu Miao, Rui-Xing Yin, Feng Huang, Wu-Xian Chen, Xiao-Li Cao,  and Jin-Zhen Wu
72801-72817
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Neutrophils protect lymphoma cells against cytotoxic and targeted therapies through CD11b/ICAM-1 binding

Neutrophils protect lymphoma cells against cytotoxic and targeted therapies through CD11b/ICAM-1 binding

https://doi.org/10.18632/oncotarget.20350

Taghreed Hirz, Eva-Laure Matera, Kamel Chettab, Lars Petter Jordheim, Doriane Mathé, Anne Evesque, Justine Esmenjaud, Gilles Salles,  and Charles Dumontet
72818-72834
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The miR-486-5p plays a causative role in prostate cancer through negative regulation of multiple tumor suppressor pathways

The miR-486-5p plays a causative role in prostate cancer through negative regulation of multiple tumor suppressor pathways

https://doi.org/10.18632/oncotarget.20427

Yang Yang, Changwei Ji, Suhan Guo, Xin Su, Xiaozhi Zhao, Shiwei Zhang, Guangxiang Liu, Xuefeng Qiu, Qing Zhang, Hongqian Guo,  and Huimei Chen
72835-72846
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Protein-coding genes, long non-coding RNAs combined with microRNAs as a novel clinical multi-dimension transcriptome signature to predict prognosis in ovarian cancer

Protein-coding genes, long non-coding RNAs combined with microRNAs as a novel clinical multi-dimension transcriptome signature to predict prognosis in ovarian cancer

https://doi.org/10.18632/oncotarget.20457

Xu Meng, Guo Jin-Cheng, Zhang Jue, Ma Quan-Fu, Yan Bin,  and Wu Xu-Feng
72847-72859
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Stereotactic ablative body radiotherapy for spinal metastasis from hepatocellular carcinoma: its oncologic outcomes and risk of vertebral compression fracture

Stereotactic ablative body radiotherapy for spinal metastasis from hepatocellular carcinoma: its oncologic outcomes and risk of vertebral compression fracture

https://doi.org/10.18632/oncotarget.20529

Gyu Sang Yoo, Hee Chul Park, Jeong Il Yu, Do Hoon Lim, Won Kyung Cho, Eonju Lee, Sang Hoon Jung, Youngyih Han, Eun-Sang Kim, Sun-Ho Lee, Whan Eoh, Se-Jun Park, Sung-Soo Chung, Chong-Suh Lee,  and Joon Hyuk Lee
72860-72871
Abstract  |  PDF  |  HTML  |  Order a Reprint

Acylated and unacylated ghrelin inhibit atrophy in myotubes co-cultured with colon carcinoma cells

Acylated and unacylated ghrelin inhibit atrophy in myotubes co-cultured with colon carcinoma cells

https://doi.org/10.18632/oncotarget.20531

Xianliang Zeng, Sizeng Chen, Yang Yang,  and Zhao Ke
72872-72885
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Differential expression of microRNA let-7b-5p regulates burn-induced hyperglycemia

Differential expression of microRNA let-7b-5p regulates burn-induced hyperglycemia

https://doi.org/10.18632/oncotarget.20543

Yajie Zhang, Bin Yin, Bin Shu, Zhen Liu, Hong Ding,  and Chiyu Jia
72886-72892
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PDZ-containing 1 acts as a suppressor of pancreatic cancer by regulating PTEN phosphorylation

PDZ-containing 1 acts as a suppressor of pancreatic cancer by regulating PTEN phosphorylation

https://doi.org/10.18632/oncotarget.20552

Qiang Ma, Xiuxiu Wu, Jing Wu, Huanwen Wu, Ying Xiao, Lili Wang, Zhiyong Liang,  and Tonghua Li
72893-72909
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5-HT induces PPAR γ reduction and proliferation of pulmonary artery smooth muscle cells via modulating GSK-3β/β-catenin pathway

5-HT induces PPAR γ reduction and proliferation of pulmonary artery smooth muscle cells via modulating GSK-3β/β-catenin pathway

https://doi.org/10.18632/oncotarget.20582

Rui Ke, Xinming Xie, Shaojun Li, Yilin Pan, Jian Wang, Xin Yan, Weijin Zang, Li Gao,  and Manxiang Li
72910-72920
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Meta-Analysis

Genetic analysis of the Vitamin D receptor start codon polymorphism (FokI) in cervical vertebra and lumbar spine pathologies: a meta-analysis

Genetic analysis of the Vitamin D receptor start codon polymorphism (FokI) in cervical vertebra and lumbar spine pathologies: a meta-analysis

https://doi.org/10.18632/oncotarget.20380

Xinyu Hu, Min Liu, Yanjun Ni,  and Guolong Zhang
72921-72932
Abstract  |  PDF  |  HTML  |  Order a Reprint

The MMP2 rs243865 polymorphism increases the risk of prostate cancer: A meta-analysis

The MMP2 rs243865 polymorphism increases the risk of prostate cancer: A meta-analysis

https://doi.org/10.18632/oncotarget.18014

Kun Liu, Shuo Gu, Xuzhong Liu, Qing Sun, Yunyan Wang, Junsong Meng,  and Zongyuan Xu
72933-72938
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GSTP1 polymorphism predicts treatment outcome and toxicities for breast cancer

GSTP1 polymorphism predicts treatment outcome and toxicities for breast cancer

https://doi.org/10.18632/oncotarget.18513

Jie Ma, Shao-Liang Zhu, Yang Liu, Xiang-Yang Huang,  and Dan-Ke Su
72939-72949
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Role of nab-paclitaxel in metastatic breast cancer: a meta-analysis of randomized clinical trials

Role of nab-paclitaxel in metastatic breast cancer: a meta-analysis of randomized clinical trials

https://doi.org/10.18632/oncotarget.18900

Yun Liu, Guoxin Ye, Dali Yan, Lei Zhang, Fan Fan,  and Jifeng Feng
72950-72958
Abstract  |  PDF  |  HTML  |  Order a Reprint

Meta-analysis reveals gender difference in the association of liver cancer incidence and excess BMI

Meta-analysis reveals gender difference in the association of liver cancer incidence and excess BMI

https://doi.org/10.18632/oncotarget.20127

Kun-Fang Yao, Ming Ma, Guo-Yong Ding, Zhan-Ming Li, Hui-Ling Chen, Bing Han, Qiang Chen, Xin-Quan Jiang,  and Li-Shun Wang
72959-72971
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Impact of hyperlipidemia and atrial fibrillation on the efficacy of endovascular treatment for acute ischemic stroke: a meta-analysis

Impact of hyperlipidemia and atrial fibrillation on the efficacy of endovascular treatment for acute ischemic stroke: a meta-analysis

https://doi.org/10.18632/oncotarget.20183

Jingwei Zheng, Ligen Shi, Weilin Xu, Ningning Zhao, Feng Liang, Jingyi Zhou,  and Jianmin Zhang
72972-72984
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The diagnostic value of serum creatinine and cystatin c in evaluating glomerular filtration rate in patients with chronic kidney disease: a systematic literature review and meta-analysis

The diagnostic value of serum creatinine and cystatin c in evaluating glomerular filtration rate in patients with chronic kidney disease: a systematic literature review and meta-analysis

https://doi.org/10.18632/oncotarget.20271

Xilian Qiu, Chunyong Liu, Yuqiu Ye, Huiqun Li, Yanbing Chen, Yongmei Fu, Zhenjie Liu, Xianzhang Huang, Yunqiang Zhang, Xueyuan Liao, Hongyong Liu, Wenbo Zhao,  and Xun Liu
72985-72999
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Statins reduce all-cause mortality in chronic obstructive pulmonary disease: an updated systematic review and meta-analysis of observational studies

Statins reduce all-cause mortality in chronic obstructive pulmonary disease: an updated systematic review and meta-analysis of observational studies

https://doi.org/10.18632/oncotarget.20304

Wen-Feng Li, Yu-Qing Huang, Cheng Huang,  and Ying-Qing Feng
73000-73008
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The addition of bevacizumab in the first-line treatment for metastatic colorectal cancer: an updated meta-analysis of randomized trials

The addition of bevacizumab in the first-line treatment for metastatic colorectal cancer: an updated meta-analysis of randomized trials

https://doi.org/10.18632/oncotarget.20314

Hyun Joo Jang, Bum Jun Kim, Jung Han Kim,  and Hyeong Su Kim
73009-73016
Abstract  |  PDF  |  HTML  |  Order a Reprint

The meta and bioinformatics analysis of GRP78 expression in gastric cancer

The meta and bioinformatics analysis of GRP78 expression in gastric cancer

https://doi.org/10.18632/oncotarget.20318

Hua-Chuan Zheng, Bao-Cheng Gong,  and Shuang Zhao
73017-73028
Abstract  |  PDF  |  HTML  |  Order a Reprint

Expression of the long non-coding RNA HOTAIR as a prognostic factor in squamous cell carcinoma of the head and neck: a systematic review and meta-analysis

Expression of the long non-coding RNA HOTAIR as a prognostic factor in squamous cell carcinoma of the head and neck: a systematic review and meta-analysis

https://doi.org/10.18632/oncotarget.20373

Giuseppe Troiano, Vito Carlo Alberto Caponio, Linda Boldrup, Xiaolian Gu, Lorenzo Lo Muzio, Nicola Sgaramella, Lixiao Wang,  and Karin Nylander
73029-73036
Abstract  |  PDF  |  HTML  |  Order a Reprint

The effect of pathological fractures on the prognosis of patients with osteosarcoma: a meta-analysis of 14 studies

The effect of pathological fractures on the prognosis of patients with osteosarcoma: a meta-analysis of 14 studies

https://doi.org/10.18632/oncotarget.20375

Yifei Zhou, Qian Lu, Jifeng Xu, Ruijian Yan, Junkun Zhu, Juntao Xu, Xuesheng Jiang, Jianyou Li,  and Fengfeng Wu
73037-73049
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Efficacy and safety of immunosuppressive medications for steroid-resistant nephrotic syndrome in children: a systematic review and network meta-analysis

Efficacy and safety of immunosuppressive medications for steroid-resistant nephrotic syndrome in children: a systematic review and network meta-analysis

https://doi.org/10.18632/oncotarget.20377

Shaojun Li, Haiping Yang, Pengfei Guo, Xiaoxiao Ao, Junli Wan, Qiu Li,  and Liping Tan
73050-73062
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Association of four genetic polymorphisms in the vascular endothelial growth factor-A gene and development of ovarian cancer: a meta-analysis

Association of four genetic polymorphisms in the vascular endothelial growth factor-A gene and development of ovarian cancer: a meta-analysis

https://doi.org/10.18632/oncotarget.20379

Chao-Huan Xu, Zhong-Hui He,  and Hong Xu
73063-73078
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Metformin use and survival outcomes in endometrial cancer: a systematic review and meta-analysis

Metformin use and survival outcomes in endometrial cancer: a systematic review and meta-analysis

https://doi.org/10.18632/oncotarget.20388

Weimin Xie, Tianjia Li, Jing Yang, Mengmeng Shang, Ying Xiao, Qian Li,  and Jiaxin Yang
73079-73086
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Discrepancies on the association between androgen deprivation therapy for prostate cancer and subsequent dementia: meta-analysis and meta-regression

Discrepancies on the association between androgen deprivation therapy for prostate cancer and subsequent dementia: meta-analysis and meta-regression

https://doi.org/10.18632/oncotarget.20391

Jae Heon Kim, Bora Lee, Deok Hyun Han, Kyoung Jin Chung, In Gab Jeong,  and Benjamin I. Chung
73087-73097
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic value of c-Met overexpression in pancreatic adenocarcinoma: a meta-analysis

Prognostic value of c-Met overexpression in pancreatic adenocarcinoma: a meta-analysis

https://doi.org/10.18632/oncotarget.20392

Jung Han Kim, Hyeong Su Kim, Bum Jun Kim, Jin Lee,  and Hyun Joo Jang
73098-73104
Abstract  |  PDF  |  HTML  |  Order a Reprint

Diagnostic ability of intraoperative ultrasound for identifying tumor residual in glioma surgery operation

Diagnostic ability of intraoperative ultrasound for identifying tumor residual in glioma surgery operation

https://doi.org/10.18632/oncotarget.20394

Guangying Zhang, Zhanzhan Li, Daolin Si,  and Liangfang Shen
73105-73114
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical Research Papers

Postoperative CYFRA 21-1 and CEA as prognostic factors in patients with stage I pulmonary adenocarcinoma

Postoperative CYFRA 21-1 and CEA as prognostic factors in patients with stage I pulmonary adenocarcinoma

https://doi.org/10.18632/oncotarget.17611

Ying He, Yong Cui, Dong Chang,  and Tianyou Wang
73115-73122
Abstract  |  PDF  |  HTML  |  Order a Reprint

Rectovaginal fistula after low anterior resection in Chinese patients with colorectal cancer

Rectovaginal fistula after low anterior resection in Chinese patients with colorectal cancer

https://doi.org/10.18632/oncotarget.17046

Hongtu Zheng, Tianan Guo, Yuchen Wu, Cong Li, Sanjun Cai, Fangqi Liu,  and Ye Xu
73123-73132
Abstract  |  PDF  |  HTML  |  Order a Reprint

Association of lower body mass index with increased glycemic variability in patients with newly diagnosed type 2 diabetes: a cross-sectional study in China

Association of lower body mass index with increased glycemic variability in patients with newly diagnosed type 2 diabetes: a cross-sectional study in China

https://doi.org/10.18632/oncotarget.17111

Jian Wang, Rengna Yan, Juan Wen, Xiaocen Kong, Huiqin Li, Peihua Zhou, Honghong Zhu, Xiaofei Su,  and Jianhua Ma
73133-73143
Abstract  |  PDF  |  HTML  |  Order a Reprint

A phase I study of the SRC kinase inhibitor dasatinib with trastuzumab and paclitaxel as first line therapy for patients with HER2-overexpressing advanced breast cancer. GEICAM/2010-04 study

A phase I study of the SRC kinase inhibitor dasatinib with trastuzumab and paclitaxel as first line therapy for patients with HER2-overexpressing advanced breast cancer. GEICAM/2010-04 study

https://doi.org/10.18632/oncotarget.17113

Alberto Ocana, Marta Gil-Martin, Miguel Martín, Federico Rojo, Silvia Antolín, Ángel Guerrero, José Manuel Trigo, Montse Muñoz, Atanasio Pandiella, Núria Gonzalo Diego, Susana Bezares, Rosalía Caballero, Eva Carrasco,  and Ander Urruticoechea
73144-73153
Abstract  |  PDF  |  HTML  |  Order a Reprint

Hepatocellular carcinoma in hemodialysis patients

Hepatocellular carcinoma in hemodialysis patients

https://doi.org/10.18632/oncotarget.17127

Chern-Horng Lee, Sen-Yung Hsieh, Chih-Chun Chang, I-Kuan Wang, Wen-Hung Huang, Cheng-Hao Weng, Ching-Wei Hsu,  and Tzung-Hai Yen
73154-73161
Abstract  |  PDF  |  HTML  |  Order a Reprint

Primary malignant melanoma of the cervix: Report of 14 cases and review of literature

Primary malignant melanoma of the cervix: Report of 14 cases and review of literature

https://doi.org/10.18632/oncotarget.17183

Guangwen Yuan, Lingying Wu, Bin Li,  and Jusheng An
73162-73167
Abstract  |  PDF  |  HTML  |  Order a Reprint

Prognostic analysis of DLBCL patients and the role of upfront ASCT in high-intermediate and high-risk patients

Prognostic analysis of DLBCL patients and the role of upfront ASCT in high-intermediate and high-risk patients

https://doi.org/10.18632/oncotarget.17324

Ying Zhao, Hong Wang, Song Jin, Jiajia Zheng, Man Huang, Yaqiong Tang, Zhengming Jin, Huiying Qiu, Xiaowen Tang, Chengcheng Fu, Yue Han,  and De-Pei Wu
73168-73176
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Higher N stage and serum ferritin, but lower serum albumin levels are associated with distant metastasis and poor survival in patients with nasopharyngeal carcinoma following intensity-modulated radiotherapy

Higher N stage and serum ferritin, but lower serum albumin levels are associated with distant metastasis and poor survival in patients with nasopharyngeal carcinoma following intensity-modulated radiotherapy

https://doi.org/10.18632/oncotarget.17418

Xiaoqian Chen, Xianfeng Long, Zhongguo Liang, Hao Lei, Ling Li, Song Qu,  and Xiaodong Zhu
73177-73186
Abstract  |  PDF  |  HTML  |  Order a Reprint

The relationship among cardiac structure, dietary salt and aldosterone in patients with primary aldosteronism

The relationship among cardiac structure, dietary salt and aldosterone in patients with primary aldosteronism

https://doi.org/10.18632/oncotarget.17505

Chi-Sheng Hung, Xue-Ming Wu, Ching-Way Chen, Ying-Hsien Chen, Vin-Cent Wu, Che-Wei Liao, Yi-Yao Chang, Ruh-Fang Yen, Ching-Chu Lu, Mao-Yuan M. Su, Kao-Lang Liu, Chin-Chen Chang, Li-Yu Daisy Liu, Kwan-Dun Wu, Yen-Hung Lin,  and the TAIPAI study group
73187-73197
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Combination of platelet count and lymphocyte to monocyte ratio is a prognostic factor in patients undergoing surgery for non-small cell lung cancer

Combination of platelet count and lymphocyte to monocyte ratio is a prognostic factor in patients undergoing surgery for non-small cell lung cancer

https://doi.org/10.18632/oncotarget.18336

Wei Liu, Minwen Ha,  and Nanchang Yin
73198-73207
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Reviews

Single-cell genomic analysis of head and neck squamous cell carcinoma

Single-cell genomic analysis of head and neck squamous cell carcinoma

https://doi.org/10.18632/oncotarget.18021

Andres Stucky, Parish P. Sedghizadeh, Susan Mahabady, Xuelian Chen, Cheng Zhang, Gang Zhang, Xi Zhang,  and Jiang F. Zhong
73208-73218
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S100A4 in cancer progression and metastasis: A systematic review

S100A4 in cancer progression and metastasis: A systematic review

https://doi.org/10.18632/oncotarget.18016

Fei Fei, Jie Qu, Mingqing Zhang, Yuwei Li,  and Shiwu Zhang
73219-73239
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Germline mutations in pancreatic cancer and potential new therapeutic options

Germline mutations in pancreatic cancer and potential new therapeutic options

https://doi.org/10.18632/oncotarget.17291

Rille Pihlak, Juan W. Valle,  and Mairéad G. McNamara
73240-73257
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Erlotinib-based doublet targeted therapy versus erlotinib alone in previously treated advanced non-small-cell lung cancer: a meta-analysis from 24 randomized controlled trials

Erlotinib-based doublet targeted therapy versus erlotinib alone in previously treated advanced non-small-cell lung cancer: a meta-analysis from 24 randomized controlled trials

https://doi.org/10.18632/oncotarget.18319

Jian-Wei Gao, Ping Zhan, Xiang-Yu Qiu, Jia-Jia Jin, Tang-Feng Lv,  and Yong Song
73258-73270
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An emerging function of circRNA-miRNAs-mRNA axis in human diseases

An emerging function of circRNA-miRNAs-mRNA axis in human diseases

https://doi.org/10.18632/oncotarget.19154

Dawei Rong, Handong Sun, Zhouxiao Li, Shuheng Liu, Chaoxi Dong, Kai Fu, Weiwei Tang,  and Hongyong Cao
73271-73281
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Potential applications of MEG3 in cancer diagnosis and prognosis

Potential applications of MEG3 in cancer diagnosis and prognosis

https://doi.org/10.18632/oncotarget.19931

Yuqing He, Yanhong Luo, Biyu Liang, Lei Ye, Guangxing Lu,  and Weiming He
73282-73295
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Tumor-educated mesenchymal stem cells promote pro-metastatic phenotype

Tumor-educated mesenchymal stem cells promote pro-metastatic phenotype

https://doi.org/10.18632/oncotarget.20265

Billy Samuel Hill, Alessandra Pelagalli, Nunzia Passaro,  and Antonella Zannetti
73296-73311
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Leptomeningeal disease: current diagnostic and therapeutic strategies

Leptomeningeal disease: current diagnostic and therapeutic strategies

https://doi.org/10.18632/oncotarget.20272

Gautam Nayar, Tiffany Ejikeme, Pakawat Chongsathidkiet, Aladine A. Elsamadicy, Kimberly L. Blackwell, Jeffrey M. Clarke, Shivanand P. Lad,  and Peter E. Fecci
73312-73328
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Potential therapeutic targets of triple-negative breast cancer based on its intrinsic subtype

Potential therapeutic targets of triple-negative breast cancer based on its intrinsic subtype

https://doi.org/10.18632/oncotarget.20274

Fangyuan Shao, Heng Sun,  and Chu-Xia Deng
73329-73344
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Prognostic value of microRNA expression levels in pancreatic adenocarcinoma: a review of the literature

Prognostic value of microRNA expression levels in pancreatic adenocarcinoma: a review of the literature

https://doi.org/10.18632/oncotarget.20277

Patrick Wald, X. Shawn Liu, Cory Pettit, Mary Dillhoff, Andrei Manilchuk, Carl Schmidt, Evan Wuthrick, Wei Chen,  and Terence M. Williams
73345-73361
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