Oncotarget

Vol 7, No 36

September 6, 2016

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About The Cover

The cover for issue 36 of Oncotarget features Figure 7 (Schematic model of regulatory pathways involved in MYCN turnover) from Vaughan, et al

Table of Contents

Editorial: Autophagy and Cell Death

The gasdermin-D pore: Executor of pyroptotic cell death

The gasdermin-D pore: Executor of pyroptotic cell death

https://doi.org/10.18632/oncotarget.11421

Sebastian Rühl,  and Petr Broz
57481-57482
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Commentary: Autophagy and Cell Death

RIPK3-dependent cell death and inflammasome activation in FLT3-ITD expressing LICs

RIPK3-dependent cell death and inflammasome activation in FLT3-ITD expressing LICs

https://doi.org/10.18632/oncotarget.11195

Ulrike Höckendorf, Monica Yabal,  and Philipp J. Jost
57483-57484
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Research Perspective: Pathology

Conditional ablation of HDAC3 in islet beta cells results in glucose intolerance and enhanced susceptibility to STZ-induced diabetes

Conditional ablation of HDAC3 in islet beta cells results in glucose intolerance and enhanced susceptibility to STZ-induced diabetes

https://doi.org/10.18632/oncotarget.11295

Wen-Bin Chen, Ling Gao, Jie Wang, Yan-Gang Wang, Zheng Dong, Jiajun Zhao, Qing-Sheng Mi,  and Li Zhou
57485-57497
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Research Perspective: Immunology

Kukoamine B promotes TLR4-independent lipopolysaccharide uptake in murine hepatocytes

Kukoamine B promotes TLR4-independent lipopolysaccharide uptake in murine hepatocytes

https://doi.org/10.18632/oncotarget.11292

Dong Yang, Xinchuan Zheng, Ning Wang, Shijun Fan, Yongjun Yang, Yongling Lu, Qian Chen, Xin Liu,  and Jiang Zheng
57498-57513
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Priority Research Papers

NFIB overexpression cooperates with Rb/p53 deletion to promote small cell lung cancer

NFIB overexpression cooperates with Rb/p53 deletion to promote small cell lung cancer

https://doi.org/10.18632/oncotarget.11583

Nan Wu, Deshui Jia, Ali H. Ibrahim, Cindy J. Bachurski, Richard M. Gronostajski,  and David MacPherson
57514-57524
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Inhibition of mTOR-kinase destabilizes MYCN and is a potential therapy for MYCN-dependent tumors

Inhibition of mTOR-kinase destabilizes MYCN and is a potential therapy for MYCN-dependent tumors

https://doi.org/10.18632/oncotarget.10544

Lynsey Vaughan, Paul A. Clarke, Karen Barker, Yvan Chanthery, Clay W. Gustafson, Elizabeth Tucker, Jane Renshaw, Florence Raynaud, Xiaodun Li, Rosemary Burke, Yann Jamin, Simon P. Robinson, Andrew Pearson, Michel Maira, William A. Weiss, Paul Workman,  and Louis Chesler
57525-57544
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Interview with Dr. Louis Chesler  |  Order a Reprint

Research Papers: Pathology

Chronic obstructive sleep apnea accelerates pulmonary remodeling via TGF-β/miR-185/CoLA1 signaling in a canine model

Chronic obstructive sleep apnea accelerates pulmonary remodeling via TGF-β/miR-185/CoLA1 signaling in a canine model

https://doi.org/10.18632/oncotarget.11296

Xue Ding, Chengyuan Yu, Yang Liu, Sen Yan, Wenpeng Li, Dingyu Wang, Li Sun, Yu Han, Minghui Li, Song Zhang, Fengxiang Yun, Hongwei Zhao,  and Yue Li
57545-57555
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Spatial learning and memory impairments are associated with increased neuronal activity in 5XFAD mouse as measured by manganese-enhanced magnetic resonance imaging

Spatial learning and memory impairments are associated with increased neuronal activity in 5XFAD mouse as measured by manganese-enhanced magnetic resonance imaging

https://doi.org/10.18632/oncotarget.11353

Xiang Tang, Di Wu, Li-Hua Gu, Bin-Bin Nie, Xin-Yang Qi, Yan-Juan Wang, Fang-Fang Wu, Xiao-Li Li, Feng Bai, Xiao-Chun Chen, Lin Xu, Qing-Guo Ren,  and Zhi-Jun Zhang
57556-57570
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A novel polymer-free ciglitazone-coated vascular stent: in vivo and ex vivo analysis of stent endothelialization in a rabbit iliac artery model

A novel polymer-free ciglitazone-coated vascular stent: in vivo and ex vivo analysis of stent endothelialization in a rabbit iliac artery model

https://doi.org/10.18632/oncotarget.11584

Sylvia Otto, Kristin Jaeger, Frank D. Kolodgie, Diana Muehlstaedt, Marcus Franz, Sabine Bischoff, Harald Schubert, Hans R. Figulla, Renu Virmani,  and Tudor C. Poerner
57571-57580
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Research Papers: Immunology

Identification of novel host biomarkers in plasma as candidates for the immunodiagnosis of tuberculosis disease and monitoring of tuberculosis treatment response

Identification of novel host biomarkers in plasma as candidates for the immunodiagnosis of tuberculosis disease and monitoring of tuberculosis treatment response

https://doi.org/10.18632/oncotarget.11420

Ruschca Jacobs, Stephanus Malherbe, Andre G. Loxton, Kim Stanley, Gian van der Spuy, Gerhard Walzl,  and Novel N. Chegou
57581-57592
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Downregulation of the phosphatase JKAP/DUSP22 in T cells as a potential new biomarker of systemic lupus erythematosus nephritis

Downregulation of the phosphatase JKAP/DUSP22 in T cells as a potential new biomarker of systemic lupus erythematosus nephritis

https://doi.org/10.18632/oncotarget.11419

Huai-Chia Chuang, Yi-Ming Chen, Wei-Ting Hung, Ju-Pi Li, Der-Yuan Chen, Joung-Liang Lan,  and Tse-Hua Tan
57593-57605
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Expression and regulation of immune-modulatory enzyme indoleamine 2,3-dioxygenase (IDO) by human airway epithelial cells and its effect on T cell activation

Expression and regulation of immune-modulatory enzyme indoleamine 2,3-dioxygenase (IDO) by human airway epithelial cells and its effect on T cell activation

https://doi.org/10.18632/oncotarget.11586

Wejdan A. Aldajani, Fabián Salazar, Herb F. Sewell, Alan Knox,  and Amir M. Ghaemmaghami
57606-57617
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Research Papers

Selenoprotein W redox-regulated Ca2+ channels correlate with selenium deficiency-induced muscles Ca2+ leak

Selenoprotein W redox-regulated Ca2+ channels correlate with selenium deficiency-induced muscles Ca2+ leak

https://doi.org/10.18632/oncotarget.11459

Haidong Yao, Ruifeng Fan, Xia Zhao, Wenchao Zhao, Wei Liu, Jie Yang, Hamid Sattar, Jinxin Zhao, Ziwei Zhang,  and Shiwen Xu
57618-57632
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Fibroblast growth factor receptor 4 (FGFR4) and fibroblast growth factor 19 (FGF19) autocrine enhance breast cancer cells survival

Fibroblast growth factor receptor 4 (FGFR4) and fibroblast growth factor 19 (FGF19) autocrine enhance breast cancer cells survival

https://doi.org/10.18632/oncotarget.9328

Kai Hung Tiong, Boon Shing Tan, Heng Lungh Choo, Felicia Fei-Lei Chung, Ling-Wei Hii, Si Hoey Tan, Nelson Tze Woei Khor, Shew Fung Wong, Sze-Jia See, Yuen-Fen Tan, Rozita Rosli, Soon-Keng Cheong,  and Chee-Onn Leong
57633-57650
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Acquired savolitinib resistance in non-small cell lung cancer arises via multiple mechanisms that converge on MET-independent mTOR and MYC activation

Acquired savolitinib resistance in non-small cell lung cancer arises via multiple mechanisms that converge on MET-independent mTOR and MYC activation

https://doi.org/10.18632/oncotarget.10859

Ryan E. Henry, Evan R. Barry, Lillian Castriotta, Brendon Ladd, Aleksandra Markovets, Garry Beran, Yongxin Ren, Feng Zhou, Ammar Adam, Michael Zinda, Corinne Reimer, Weiguo Qing, Weiguo Su, Edwin Clark, Celina M. D’Cruz,  and Alwin G. Schuller
57651-57670
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Cancer megafunds with in silico and in vitro validation: accelerating cancer drug discovery via financial engineering without financial crisis

Cancer megafunds with in silico and in vitro validation: accelerating cancer drug discovery via financial engineering without financial crisis

https://doi.org/10.18632/oncotarget.9808

Xianjin Yang, Edouard Debonneuil, Alex Zhavoronkov,  and Bud Mishra
57671-57678
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Impaired 53BP1/RIF1 DSB mediated end-protection stimulates CtIP-dependent end resection and switches the repair to PARP1-dependent end joining in G1

Impaired 53BP1/RIF1 DSB mediated end-protection stimulates CtIP-dependent end resection and switches the repair to PARP1-dependent end joining in G1

https://doi.org/10.18632/oncotarget.11023

Ali Bakr, Sabrina Köcher, Jennifer Volquardsen, Cordula Petersen, Kerstin Borgmann, Ekkehard Dikomey, Kai Rothkamm,  and Wael Y. Mansour
57679-57693
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Circulating resistin levels and obesity-related cancer risk: A meta-analysis

Circulating resistin levels and obesity-related cancer risk: A meta-analysis

https://doi.org/10.18632/oncotarget.11034

Wei-Jing Gong, Wei Zheng, Ling Xiao, Li-Ming Tan, Jian Song, Xiang-Ping Li, Di Xiao, Jia-Jia Cui, Xi Li, Hong-Hao Zhou, Ji-Ye Yin,  and Zhao-Qian Liu
57694-57704
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A novel multi-target RNAi adenovirus inhibits hepatoma cell proliferation, migration, and induction of angiogenesis

A novel multi-target RNAi adenovirus inhibits hepatoma cell proliferation, migration, and induction of angiogenesis

https://doi.org/10.18632/oncotarget.9531

Mei Huang, Guangyao Li, Tingting Pan, Ya Cheng, Weihua Ren, Weidong Jia, Jinliang Ma,  and Geliang Xu
57705-57713
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

ATM protein is deficient in over 40% of lung adenocarcinomas

ATM protein is deficient in over 40% of lung adenocarcinomas

https://doi.org/10.18632/oncotarget.9757

Liza C. Villaruz, Helen Jones, Sanja Dacic, Shira Abberbock, Brenda F. Kurland, Laura P. Stabile, Jill M. Siegfried, Thomas P. Conrads, Neil R. Smith, Mark J. O'Connor, Andrew J. Pierce,  and Christopher J. Bakkenist
57714-57725
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A cancer specific hypermethylation signature of the TERT promoter predicts biochemical relapse in prostate cancer: a retrospective cohort study

A cancer specific hypermethylation signature of the TERT promoter predicts biochemical relapse in prostate cancer: a retrospective cohort study

https://doi.org/10.18632/oncotarget.10639

Pedro Castelo-Branco, Ricardo Leão, Tatiana Lipman, Brittany Campbell, Donghyun Lee, Aryeh Price, Cindy Zhang, Abolfazl Heidari, Derek Stephens, Stefan Boerno, Hugo Coelho, Ana Gomes, Celia Domingos, Joana D. Apolonio, Georg Schäfer, Robert G. Bristow, Michal R. Schweiger, Robert Hamilton, Alexandre Zlotta, Arnaldo Figueiredo, Helmut Klocker, Holger Sültmann,  and Uri Tabori
57726-57736
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

CD147 knockdown improves the antitumor efficacy of trastuzumab in HER2-positive breast cancer cells

CD147 knockdown improves the antitumor efficacy of trastuzumab in HER2-positive breast cancer cells

https://doi.org/10.18632/oncotarget.10252

Lijuan Xiong, Li Ding, Haoyong Ning, Chenglin Wu, Kaifei Fu, Yuxiao Wang, Yan Zhang, Yan Liu,  and Lijun Zhou
57737-57751
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Honokiol suppresses lung tumorigenesis by targeting EGFR and its downstream effectors

Honokiol suppresses lung tumorigenesis by targeting EGFR and its downstream effectors

https://doi.org/10.18632/oncotarget.10759

Jung Min Song, Arunkumar Anandharaj, Pramod Upadhyaya, Ameya R. Kirtane, Jong-Hyuk Kim, Kwon Ho Hong, Jayanth Panyam,  and Fekadu Kassie
57752-57769
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Src-like adaptor protein 2 (SLAP2) binds to and inhibits FLT3 signaling

Src-like adaptor protein 2 (SLAP2) binds to and inhibits FLT3 signaling

https://doi.org/10.18632/oncotarget.10760

Sausan A. Moharram, Rohit A. Chougule, Xianwei Su, Tianfeng Li, Jianmin Sun, Hui Zhao, Lars Rönnstrand,  and Julhash U. Kazi
57770-57782
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Role of SATB2 in human pancreatic cancer: Implications in transformation and a promising biomarker

Role of SATB2 in human pancreatic cancer: Implications in transformation and a promising biomarker

https://doi.org/10.18632/oncotarget.10860

Wei Yu, Yiming Ma, Sharmila Shankar,  and Rakesh K. Srivastava
57783-57797
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Her2 oncogene transformation enhances 5-aminolevulinic acid-mediated protoporphyrin IX production and photodynamic therapy response

Her2 oncogene transformation enhances 5-aminolevulinic acid-mediated protoporphyrin IX production and photodynamic therapy response

https://doi.org/10.18632/oncotarget.11058

Xue Yang, Pratheeba Palasuberniam, Kenneth A. Myers, Chenguang Wang,  and Bin Chen
57798-57810
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Acute myeloid leukemia stem cell markers in prognosis and targeted therapy: potential impact of BMI-1, TIM-3 and CLL-1

Acute myeloid leukemia stem cell markers in prognosis and targeted therapy: potential impact of BMI-1, TIM-3 and CLL-1

https://doi.org/10.18632/oncotarget.11063

Noureldien H.E. Darwish, Thangirala Sudha, Kavitha Godugu, Osama Elbaz, Hasan A. Abdelghaffar, Emad E.A. Hassan,  and Shaker A. Mousa
57811-57820
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

UHRF1 regulates global DNA hypomethylation and is associated with poor prognosis in esophageal squamous cell carcinoma

UHRF1 regulates global DNA hypomethylation and is associated with poor prognosis in esophageal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.11067

Kenichi Nakamura, Yoshifumi Baba, Keisuke Kosumi, Kazuto Harada, Hironobu Shigaki, Keisuke Miyake, Yuki Kiyozumi, Mayuko Ohuchi, Junji Kurashige, Takatsugu Ishimoto, Masaaki Iwatsuki, Yasuo Sakamoto, Naoya Yoshida, Masayuki Watanabe, Mitsuyoshi Nakao,  and Hideo Baba
57821-57831
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

PTEN expression is a prognostic marker for patients with non-small cell lung cancer: a systematic review and meta-analysis of the literature

PTEN expression is a prognostic marker for patients with non-small cell lung cancer: a systematic review and meta-analysis of the literature

https://doi.org/10.18632/oncotarget.11068

Jian Xiao, Cheng-Ping Hu, Bi-Xiu He, Xi Chen, Xiao-Xiao Lu, Ming-Xuan Xie, Wei Li, Shu-Ya He, Shao-Jin You,  and Qiong Chen
57832-57840
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Deletion of epidermal Rac1 inhibits HPV-8 induced skin papilloma formation and facilitates HPV-8- and UV-light induced skin carcinogenesis

Deletion of epidermal Rac1 inhibits HPV-8 induced skin papilloma formation and facilitates HPV-8- and UV-light induced skin carcinogenesis

https://doi.org/10.18632/oncotarget.11069

Jayesh Deshmukh, Ruth Pofahl, Herbert Pfister,  and Ingo Haase
57841-57850
Abstract  |  PDF  |  HTML  |  Order a Reprint

Inhibition of PlexA1-mediated brain tumor growth and tumor-associated angiogenesis using a transmembrane domain targeting peptide

Inhibition of PlexA1-mediated brain tumor growth and tumor-associated angiogenesis using a transmembrane domain targeting peptide

https://doi.org/10.18632/oncotarget.11072

Laurent Jacob, Paul Sawma, Norbert Garnier, Lionel A.T. Meyer, Justine Fritz, Thomas Hussenet, Caroline Spenlé, Jacky Goetz, Julien Vermot, Aurore Fernandez, Nadège Baumlin, Samia Aci-Sèche, Gertraud Orend, Guy Roussel, Gérard Crémel, Monique Genest, Pierre Hubert,  and Dominique Bagnard
57851-57865
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

KDM4B plays an important role in mitochondrial apoptosis by upregulating HAX1 expression in colorectal cancer

KDM4B plays an important role in mitochondrial apoptosis by upregulating HAX1 expression in colorectal cancer

https://doi.org/10.18632/oncotarget.11077

Haijie Li, Xi Yang, Guihua Wang, Xiaolan Li, Deding Tao, Junbo Hu,  and Xuelai Luo
57866-57877
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

RSUME is implicated in tumorigenesis and metastasis of pancreatic neuroendocrine tumors

RSUME is implicated in tumorigenesis and metastasis of pancreatic neuroendocrine tumors

https://doi.org/10.18632/oncotarget.11081

Yonghe Wu, Lucas Tedesco, Kristin Lucia, Anna M. Schlitter, Jose Monteserin Garcia, Irene Esposito, Christoph J. Auernhammer, Marily Theodoropoulou, Eduardo Arzt, Ulrich Renner,  and Günter K. Stalla
57878-57893
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Sunitinib as salvage treatment including potent anti-tumor activity in carcinomatous ulcers for patients with multidrug-resistant metastatic breast cancer

Sunitinib as salvage treatment including potent anti-tumor activity in carcinomatous ulcers for patients with multidrug-resistant metastatic breast cancer

https://doi.org/10.18632/oncotarget.11082

Bing Sun, Xin Zhao, Lijuan Ding, Xiangying Meng, Santai Song,  and Shikai Wu
57894-57902
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Long non-coding RNA ANRIL promotes the invasion and metastasis of thyroid cancer cells through TGF-β/Smad signaling pathway

Long non-coding RNA ANRIL promotes the invasion and metastasis of thyroid cancer cells through TGF-β/Smad signaling pathway

https://doi.org/10.18632/oncotarget.11087

Jian-Jie Zhao, Shuai Hao, Ling-Li Wang, Chun-Yan Hu, Shu Zhang, Ling-Ji Guo, Gang Zhang, Bo Gao, Yan Jiang, Wu-Guo Tian,  and Dong-Lin Luo
57903-57918
Abstract  |  PDF  |  HTML  |  Order a Reprint

IRWRLDA: improved random walk with restart for lncRNA-disease association prediction

IRWRLDA: improved random walk with restart for lncRNA-disease association prediction

https://doi.org/10.18632/oncotarget.11141

Xing Chen, Zhu-Hong You, Gui-Ying Yan,  and Dun-Wei Gong
57919-57931
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Anti-cancer effects of nitrogen-containing bisphosphonates on human cancer cells

Anti-cancer effects of nitrogen-containing bisphosphonates on human cancer cells

https://doi.org/10.18632/oncotarget.10773

Pengfei Jiang, Peiying Zhang, Rajesh Mukthavaram, Natsuko Nomura, Sandeep C. Pingle, Dayu Teng, Shu Chien, Fang Guo,  and Santosh Kesari
57932-57942
Abstract  |  PDF  |  HTML  |  Order a Reprint

Structural basis for exploring the allosteric inhibition of human kidney type glutaminase

Structural basis for exploring the allosteric inhibition of human kidney type glutaminase

https://doi.org/10.18632/oncotarget.10791

Sarath Ramachandran, Catherine Qiurong Pan, Sarah C. Zimmermann, Bridget Duvall, Takashi Tsukamoto, Boon Chuan Low,  and J. Sivaraman
57943-57954
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Ligand activated progesterone receptor B drives autophagy-senescence transition through a Beclin-1/Bcl-2 dependent mechanism in human breast cancer cells

Ligand activated progesterone receptor B drives autophagy-senescence transition through a Beclin-1/Bcl-2 dependent mechanism in human breast cancer cells

https://doi.org/10.18632/oncotarget.10799

Francesca De Amicis, Carmela Guido, Marta Santoro, Francesca Giordano, Ada Donà, Pietro Rizza, Michele Pellegrino, Ida Perrotta, Daniela Bonofiglio, Diego Sisci, Maria Luisa Panno, Donatella Tramontano, Saveria Aquila,  and Sebastiano Andò
57955-57969
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

DcR3 gene polymorphisms are associated with sporadic breast infiltrating ductal carcinoma in Northeast Chinese women

DcR3 gene polymorphisms are associated with sporadic breast infiltrating ductal carcinoma in Northeast Chinese women

https://doi.org/10.18632/oncotarget.11153

Zhenkun Fu, Shuang Chen, Shengwei Liu, Shaoli Han, Xiang Gao, Dalin Li,  and Dianjun Li
57970-57977
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Increased expression of EHF contributes to thyroid tumorigenesis through transcriptionally regulating HER2 and HER3

Increased expression of EHF contributes to thyroid tumorigenesis through transcriptionally regulating HER2 and HER3

https://doi.org/10.18632/oncotarget.11154

Yanyan Lv, Fang Sui, Jingjing Ma, Xiaojuan Ren, Qi Yang, Yanfang Zhang, Haixia Guan, Bingyin Shi, Peng Hou,  and Meiju Ji
57978-57990
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic value of long non-coding RNA UCA1 in human solid tumors

Prognostic value of long non-coding RNA UCA1 in human solid tumors

https://doi.org/10.18632/oncotarget.11155

Fang-teng Liu, Pei-qian Zhu, Hong-liang Luo, Yi Zhang,  and Cheng Qiu
57991-58000
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

KRAS mutation as a prognostic factor in ampullary adenocarcinoma: a meta-analysis and review

KRAS mutation as a prognostic factor in ampullary adenocarcinoma: a meta-analysis and review

https://doi.org/10.18632/oncotarget.11156

Bum Jun Kim, Hyun Joo Jang, Jung Han Kim, Hyeong Su Kim,  and Jin Lee
58001-58006
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Therapeutic implication of HER2 in advanced biliary tract cancer

Therapeutic implication of HER2 in advanced biliary tract cancer

https://doi.org/10.18632/oncotarget.11157

Ah-Rong Nam, Ji-Won Kim, Yongjun Cha, Hyerim Ha, Ji Eun Park, Ju-Hee Bang, Mei Hua Jin, Kyung-Hun Lee, Tae-Yong Kim, Sae-Won Han, Seock-Ah Im, Tae-You Kim, Do-Youn Oh,  and Yung-Jue Bang
58007-58021
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Co-expression analysis identifies long noncoding RNA SNHG1 as a novel predictor for event-free survival in neuroblastoma

Co-expression analysis identifies long noncoding RNA SNHG1 as a novel predictor for event-free survival in neuroblastoma

https://doi.org/10.18632/oncotarget.11158

Divya Sahu, Chia-Lang Hsu, Chen-Ching Lin, Tz-Wen Yang, Wen-Ming Hsu, Shinn-Ying Ho, Hsueh-Fen Juan,  and Hsuan-Cheng Huang
58022-58037
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Ethacrynic acid improves the antitumor effects of irreversible epidermal growth factor receptor tyrosine kinase inhibitors in breast cancer

Ethacrynic acid improves the antitumor effects of irreversible epidermal growth factor receptor tyrosine kinase inhibitors in breast cancer

https://doi.org/10.18632/oncotarget.10846

Bing Liu, XinPing Huang, YunLong Hu, TingTing Chen, BoYa Peng, NingNing Gao, ZhenChao Jin, TieLiu Jia, Na Zhang, ZhuLin Wang,  and GuangYi Jin
58038-58050
Abstract  |  PDF  |  HTML  |  Order a Reprint

ABCB1 as predominant resistance mechanism in cells with acquired SNS-032 resistance

ABCB1 as predominant resistance mechanism in cells with acquired SNS-032 resistance

https://doi.org/10.18632/oncotarget.11160

Nadine Löschmann, Martin Michaelis, Florian Rothweiler, Yvonne Voges, Barbora Balónová, Barry A. Blight,  and Jindrich Cinatl Jr
58051-58064
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Impaired mitophagy in Fanconi anemia is dependent on mitochondrial fission

Impaired mitophagy in Fanconi anemia is dependent on mitochondrial fission

https://doi.org/10.18632/oncotarget.11161

Pavithra Shyamsunder, Milan Esner, Maunish Barvalia, Yu Jun Wu, Tomáš Loja, Huat Bay Boon, Matilde E. Lleonart, Rama S Verma, Lumir Krejci,  and Alex Lyakhovich
58065-58074
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Simultaneous activation and inhibition of autophagy sensitizes cancer cells to chemotherapy

Simultaneous activation and inhibition of autophagy sensitizes cancer cells to chemotherapy

https://doi.org/10.18632/oncotarget.10873

Kwan-Hwa Chi, Yu-Shan Wang, Yi-Chun Huang, Hsin-Chien Chiang, Mau-Shin Chi, Chau-Hwa Chi, Hsin-Ell Wang,  and Shang-Jyh Kao
58075-58088
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Preconditioning of bone marrow mesenchymal stem cells with hydrogen sulfide improves their therapeutic potential

Preconditioning of bone marrow mesenchymal stem cells with hydrogen sulfide improves their therapeutic potential

https://doi.org/10.18632/oncotarget.11166

Qun Zhang, Song Liu, Tong Li, Lin Yuan, Hansen Liu, Xueer Wang, Fuwu Wang, Shuanglian Wang, Aijun Hao, Dexiang Liu,  and Zhen Wang
58089-58104
Abstract  |  PDF  |  HTML  |  Order a Reprint

Comparison of the EORTC criteria and PERCIST in solid tumors: a pooled analysis and review

Comparison of the EORTC criteria and PERCIST in solid tumors: a pooled analysis and review

https://doi.org/10.18632/oncotarget.11171

Jung Han Kim
58105-58110
Abstract  |  PDF  |  HTML  |  Order a Reprint

Suppression of breast cancer metastasis through the inactivation of ADP-ribosylation factor 1

Suppression of breast cancer metastasis through the inactivation of ADP-ribosylation factor 1

https://doi.org/10.18632/oncotarget.11185

Xiayang Xie, Shou-Ching Tang, Yafei Cai, Wenhu Pi, Libin Deng, Guangyu Wu, Alain Chavanieu,  and Yong Teng
58111-58120
Abstract  |  PDF  |  HTML  |  Order a Reprint

Radio-frequency plasma polymerized biodegradable carrier for in vivo release of cis-platinum

Radio-frequency plasma polymerized biodegradable carrier for in vivo release of cis-platinum

https://doi.org/10.18632/oncotarget.10932

Sudhir Bhatt, Fatemeh Valamanesh, Jerome Pulpytel, Rea Lo Dico, Aliby Baiyukha, Iman Al-dybiat, Marc Pocard, Farzaneh Arefi-Khonsari,  and Massoud Mirshahi
58121-58132
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Combretastatin-A4 phosphate improves the distribution and antitumor efficacy of albumin-bound paclitaxel in W256 breast carcinoma model

Combretastatin-A4 phosphate improves the distribution and antitumor efficacy of albumin-bound paclitaxel in W256 breast carcinoma model

https://doi.org/10.18632/oncotarget.11249

Meng Gao, Dongjian Zhang, Qiaomei Jin, Cuihua Jiang, Cong Wang, Jindian Li, Fei Peng, Dejian Huang, Jian Zhang,  and Shaoli Song
58133-58141
Abstract  |  PDF  |  HTML  |  Order a Reprint

Bromodomain inhibitor OTX015 (MK-8628) combined with targeted agents shows strong in vivo antitumor activity in lymphoma

Bromodomain inhibitor OTX015 (MK-8628) combined with targeted agents shows strong in vivo antitumor activity in lymphoma

https://doi.org/10.18632/oncotarget.10983

Eugenio Gaudio, Chiara Tarantelli, Maurilio Ponzoni, Elodie Odore, Keyvan Rezai, Elena Bernasconi, Luciano Cascione, Andrea Rinaldi, Anastasios Stathis, Eugenia Riveiro, Esteban Cvitkovic, Emanuele Zucca,  and Francesco Bertoni
58142-58147
Abstract  |  PDF  |  HTML  |  Order a Reprint

miR-497-5p inhibits cell proliferation and invasion by targeting KCa3.1 in angiosarcoma

miR-497-5p inhibits cell proliferation and invasion by targeting KCa3.1 in angiosarcoma

https://doi.org/10.18632/oncotarget.11252

Yaobing Chen, Dong Kuang, Xia Zhao, Dong Chen, Xiaoyan Wang, Qin Yang, Jie Wan, Yuanli Zhu, Yu Wang, Shiying Zhang, Ying Wang, Qiang Tang, Mikio Masuzawa, Guoping Wang,  and Yaqi Duan
58148-58161
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Matriptase regulates c-Met mediated proliferation and invasion in inflammatory breast cancer

Matriptase regulates c-Met mediated proliferation and invasion in inflammatory breast cancer

https://doi.org/10.18632/oncotarget.11262

Gina L. Zoratti, Lauren M. Tanabe, Thomas E. Hyland, Michael J. Duhaime, Éloïc Colombo, Richard Leduc, Eric Marsault, Michael D. Johnson, Chen-Yong Lin, Julie Boerner, Julie E. Lang,  and Karin List
58162-58173
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Impacts of the mTOR gene polymorphisms rs2536 and rs2295080 on breast cancer risk in the Chinese population

Impacts of the mTOR gene polymorphisms rs2536 and rs2295080 on breast cancer risk in the Chinese population

https://doi.org/10.18632/oncotarget.11272

Yang Zhao, Yan Diao, XiJing Wang, Shuai Lin, Meng Wang, HuaFeng Kang, PengTao Yang, Cong Dai, XingHan Liu, Kang Liu, ShanLi Li, YuYao Zhu,  and ZhiJun Dai
58174-58180
Abstract  |  PDF  |  HTML  |  Order a Reprint

IL-1α and IL-1β-producing macrophages populate lung tumor lesions in mice

IL-1α and IL-1β-producing macrophages populate lung tumor lesions in mice

https://doi.org/10.18632/oncotarget.11276

Michela Terlizzi, Chiara Colarusso, Ada Popolo, Aldo Pinto,  and Rosalinda Sorrentino
58181-58192
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

UBE2C cell-free RNA in urine can discriminate between bladder cancer and hematuria

UBE2C cell-free RNA in urine can discriminate between bladder cancer and hematuria

https://doi.org/10.18632/oncotarget.11277

Won Tae Kim, Pildu Jeong, Chunri Yan, Ye Hwan Kim, Il-Seok Lee, Ho-Won Kang, Yong-June Kim, Sang-Cheol Lee, Sang Jin Kim, Yong Tae Kim, Sung-Kwon Moon, Yung-Hyun Choi, Isaac Yi Kim, Seok Joong Yun,  and Wun-Jae Kim
58193-58202
Abstract  |  PDF  |  HTML  |  Order a Reprint

The putative tumor suppressor gene EphA7 is a novel BMI-1 target

The putative tumor suppressor gene EphA7 is a novel BMI-1 target

https://doi.org/10.18632/oncotarget.11279

Gaëlle Prost, Sebastian Braun, Falk Hertwig, Marcus Winkler, Lucas Jagemann, Sara Nolbrant, Isabelle V. Leefa, Nils Offen, Kenichi Miharada, Stefan Lang, Isabella Artner,  and Ulrike A. Nuber
58203-58217
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MicroRNA 744-3p promotes MMP-9-mediated metastasis by simultaneously suppressing PDCD4 and PTEN in laryngeal squamous cell carcinoma

MicroRNA 744-3p promotes MMP-9-mediated metastasis by simultaneously suppressing PDCD4 and PTEN in laryngeal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.11280

John Zeng-Hong Li, Wei Gao, Wen-Bin Lei, Jing Zhao, Jimmy Yu-Wai Chan, William Ignace Wei, Wei-Kuen Ho,  and Thian-Sze Wong
58218-58233
Abstract  |  PDF  |  HTML  |  Order a Reprint

A clinical observation of Chinese chronic myelogenous leukemia patients after discontinuation of tyrosine kinase inhibitors

A clinical observation of Chinese chronic myelogenous leukemia patients after discontinuation of tyrosine kinase inhibitors

https://doi.org/10.18632/oncotarget.11281

Qing Li, Zhaodong Zhong, Chen Zeng, Li Meng, Chunrui Li, Yi Luo, Hongxiang Wang, Weiming Li, Jue Wang, Fanjun Cheng, Anyuan Guo, Songya Liu, Caibao Jin, Xiaojian Zhu, Yong You,  and Ping Zou
58234-58243
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Proteolysis-a characteristic of tumor-initiating cells in murine metastatic breast cancer

Proteolysis-a characteristic of tumor-initiating cells in murine metastatic breast cancer

https://doi.org/10.18632/oncotarget.11309

Larissa E. Hillebrand, Fee Bengsch, Jochen Hochrein, Jan Hülsdünker, Julia Bender, Marie Follo, Hauke Busch, Melanie Boerries,  and Thomas Reinheckel
58244-58260
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Factors predicting organ-specific distant metastasis in patients with completely resected lung adenocarcinoma

Factors predicting organ-specific distant metastasis in patients with completely resected lung adenocarcinoma

https://doi.org/10.18632/oncotarget.11338

Jung-Jyh Hung, Wen-Juei Jeng, Yu-Chung Wu, Teh-Ying Chou,  and Wen-Hu Hsu
58261-58273
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

C23 promotes tumorigenesis via suppressing p53 activity

C23 promotes tumorigenesis via suppressing p53 activity

https://doi.org/10.18632/oncotarget.11071

Qun Li, Yan Zhu, Lili Hou, Juan Wang, Guilin Hu, Xing Fang, Yamin Hu, Tingting Tao, Xin Wei, Haitao Tang, Baojun Huang,  and Wanglai Hu
58274-58285
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Aberrant DR5 transport through disruption of lysosomal function suggests a novel mechanism for receptor activation

Aberrant DR5 transport through disruption of lysosomal function suggests a novel mechanism for receptor activation

https://doi.org/10.18632/oncotarget.11073

Birce Akpinar, Barbora Safarikova, Jarmila Laukova, Shubhranshu Debnath, Alena Hyrslova Vaculova, Boris Zhivotovsky,  and Magnus Olsson
58286-58301
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic nomogram for post-surgical treatment with adjuvant TACE in hepatitis B virus-related hepatocellular carcinoma

Prognostic nomogram for post-surgical treatment with adjuvant TACE in hepatitis B virus-related hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.11078

Hao Hu, Xi Kun Han, Xiao Ran Long, Jia Fan, Zhi Ping Yan, Jian Hua Wang,  and Rong Liu
58302-58314
Abstract  |  PDF  |  HTML  |  Order a Reprint

G-protein-coupled receptors mediate ω-3 PUFAs-inhibited colorectal cancer by activating the Hippo pathway

G-protein-coupled receptors mediate ω-3 PUFAs-inhibited colorectal cancer by activating the Hippo pathway

https://doi.org/10.18632/oncotarget.11089

Kun Zhang, Zhimei Hu, Haixia Qi, Zhemin Shi, Yanan Chang, Qingbin Yao, Hongmei Cui, Lina Zheng, Yawei Han, Xiaohui Han, Zhen Zhang, Ting Chen,  and Wei Hong
58315-58330
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Targeting antisense mitochondrial ncRNAs inhibits murine melanoma tumor growth and metastasis through reduction in survival and invasion factors

Targeting antisense mitochondrial ncRNAs inhibits murine melanoma tumor growth and metastasis through reduction in survival and invasion factors

https://doi.org/10.18632/oncotarget.11110

Lorena Lobos-González, Verónica Silva, Mariela Araya, Franko Restovic, Javiera Echenique, Luciana Oliveira-Cruz, Christopher Fitzpatrick, Macarena Briones, Jaime Villegas, Claudio Villota, Soledad Vidaurre, Vincenzo Borgna, Miguel Socias, Sebastián Valenzuela, Constanza Lopez, Teresa Socias, Manuel Varas, Jorge Díaz, Luis O. Burzio,  and Verónica A. Burzio
58331-58350
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

CD44 and CD24 coordinate the reprogramming of nasopharyngeal carcinoma cells towards a cancer stem cell phenotype through STAT3 activation

CD44 and CD24 coordinate the reprogramming of nasopharyngeal carcinoma cells towards a cancer stem cell phenotype through STAT3 activation

https://doi.org/10.18632/oncotarget.11113

Yao-An Shen, Chia-Yu Wang, Hui-Yen Chuang, John Jeng-Jong Hwang, Wei-Hsin Chi, Chih-Hung Shu, Ching-Yin Ho, Wing-Yin Li,  and Yann-Jang Chen
58351-58366
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Up-regulation of microRNA let-7c by quercetin inhibits pancreatic cancer progression by activation of Numbl

Up-regulation of microRNA let-7c by quercetin inhibits pancreatic cancer progression by activation of Numbl

https://doi.org/10.18632/oncotarget.11122

Clifford C. Nwaeburu, Natalie Bauer, Zhefu Zhao, Alia Abukiwan, Jury Gladkich, Axel Benner,  and Ingrid Herr
58367-58380
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Growth factor progranulin promotes tumorigenesis of cervical cancer via PI3K/Akt/mTOR signaling pathway

Growth factor progranulin promotes tumorigenesis of cervical cancer via PI3K/Akt/mTOR signaling pathway

https://doi.org/10.18632/oncotarget.11126

Tingting Feng, Lin Zheng, Feng Liu, Xiaoying Xu, Sheng Mao, Xiao Wang, Juan Liu, Yi Lu, Weiming Zhao, Xiuping Yu,  and Wei Tang
58381-58395
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The DDGP (cisplatin, dexamethasone, gemcitabine, and pegaspargase) regimen for treatment of extranodal natural killer (NK)/T-cell lymphoma, nasal type

The DDGP (cisplatin, dexamethasone, gemcitabine, and pegaspargase) regimen for treatment of extranodal natural killer (NK)/T-cell lymphoma, nasal type

https://doi.org/10.18632/oncotarget.11135

Lei Zhang, Sucai Li, Sisi Jia, Feifei Nan, Zhaoming Li, Jingyu Cao, Shanshan Fan, Chao Zhang, Liping Su, Jinghua Wang, Hongwei Xue,  and Mingzhi Zhang
58396-58404
Abstract  |  PDF  |  HTML  |  Order a Reprint

The tri-peptide GHK-Cu complex ameliorates lipopolysaccharide-induced acute lung injury in mice

The tri-peptide GHK-Cu complex ameliorates lipopolysaccharide-induced acute lung injury in mice

https://doi.org/10.18632/oncotarget.11168

Jeong-Ran Park, Hanbyeol Lee, Seok-In Kim,  and Se-Ran Yang
58405-58417
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A recombinantly tailored β-defensin that displays intensive macropinocytosis-mediated uptake exerting potent efficacy against K-Ras mutant pancreatic cancer

A recombinantly tailored β-defensin that displays intensive macropinocytosis-mediated uptake exerting potent efficacy against K-Ras mutant pancreatic cancer

https://doi.org/10.18632/oncotarget.11170

Yue Du, Bo-yang Shang, Wei-jin Sheng, Sheng-hua Zhang, Yi Li, Qing-fang Miao,  and Yong-su Zhen
58418-58434
Abstract  |  PDF  |  HTML  |  Order a Reprint

TP53 mutated glioblastoma stem-like cell cultures are sensitive to dual mTORC1/2 inhibition while resistance in TP53 wild type cultures can be overcome by combined inhibition of mTORC1/2 and Bcl-2

TP53 mutated glioblastoma stem-like cell cultures are sensitive to dual mTORC1/2 inhibition while resistance in TP53 wild type cultures can be overcome by combined inhibition of mTORC1/2 and Bcl-2

https://doi.org/10.18632/oncotarget.11205

Subramanian Venkatesan, Marlous Hoogstraat, Ester Caljouw, Tessa Pierson, Jochem K.H. Spoor, Lona Zeneyedpour, Hendrikus J. Dubbink, Lennard J. Dekker, Mariëlle van der Kaaij, Jenneke Kloezeman, Lotte M.E. Berghauser Pont, Nicolle J.M. Besselink, Theo M. Luider, Jos Joore, John W. Martens, Martine L.M. Lamfers, Stefan Sleijfer,  and Sieger Leenstra
58435-58444
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Doxorubicin-triggered self-assembly of native amphiphilic peptides into spherical nanoparticles

Doxorubicin-triggered self-assembly of native amphiphilic peptides into spherical nanoparticles

https://doi.org/10.18632/oncotarget.11213

Xiaobo Fan, Fengfeng Zhao, Xiyong Wang,  and Guoqiu Wu
58445-58458
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic values of normal preoperative serum cancer markers for gastric cancer

Prognostic values of normal preoperative serum cancer markers for gastric cancer

https://doi.org/10.18632/oncotarget.11248

Fan Feng, Li Sun, Zhen Liu, Shushang Liu, Gaozan Zheng, Guanghui Xu, Man Guo, Xiao Lian, Daiming Fan,  and Hongwei Zhang
58459-58469
Abstract  |  PDF  |  HTML  |  Order a Reprint

Elevated eukaryotic elongation factor 2 expression is involved in proliferation and invasion of lung squamous cell carcinoma

Elevated eukaryotic elongation factor 2 expression is involved in proliferation and invasion of lung squamous cell carcinoma

https://doi.org/10.18632/oncotarget.11298

Yang Song, Bing Sun, LiHong Hao, Jun Hu, Sha Du, Xin Zhou, LiYuan Zhang, Lu Liu, LinLin Gong, XinMing Chi, Qiang Liu,  and ShuJuan Shao
58470-58482
Abstract  |  PDF  |  HTML  |  Order a Reprint

DCUN1D3 activates SCFSKP2 ubiquitin E3 ligase activity and cell cycle progression under UV damage

DCUN1D3 activates SCFSKP2 ubiquitin E3 ligase activity and cell cycle progression under UV damage

https://doi.org/10.18632/oncotarget.11302

Shuai Zhang, Jing Huang, Taiping Shi, Fanlei Hu, Li Zhang, Ping-Kun Zhou, Dalong Ma, Teng Ma,  and Xiaoyan Qiu
58483-58491
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Detection of the T790M mutation of EGFR in plasma of advanced non–small cell lung cancer patients with acquired resistance to tyrosine kinase inhibitors (West Japan oncology group 8014LTR study)

Detection of the T790M mutation of EGFR in plasma of advanced non–small cell lung cancer patients with acquired resistance to tyrosine kinase inhibitors (West Japan oncology group 8014LTR study)

https://doi.org/10.18632/oncotarget.11303

Takayuki Takahama, Kazuko Sakai, Masayuki Takeda, Koichi Azuma, Toyoaki Hida, Masataka Hirabayashi, Tetsuya Oguri, Hiroshi Tanaka, Noriyuki Ebi, Toshiyuki Sawa, Akihiro Bessho, Motoko Tachihara, Hiroaki Akamatsu, Shuji Bandoh, Daisuke Himeji, Tatsuo Ohira, Mototsugu Shimokawa, Yoichi Nakanishi, Kazuhiko Nakagawa,  and Kazuto Nishio
58492-58499
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The reliable assurance of detecting somatic mutations in cancer-related genes by next-generation sequencing: the results of external quality assessment in China

The reliable assurance of detecting somatic mutations in cancer-related genes by next-generation sequencing: the results of external quality assessment in China

https://doi.org/10.18632/oncotarget.11306

Rui Zhang, Jiansheng Ding, Yanxi Han, Lang Yi, Jiehong Xie, Xin Yang, Gaowei Fan, Guojing Wang, Mingju Hao, Dong Zhang, Kuo Zhang, Guigao Lin,  and Jinming Li
58500-58515
Abstract  |  PDF  |  HTML  |  Order a Reprint

Targeting ALDH1A1 by disulfiram/copper complex inhibits non-small cell lung cancer recurrence driven by ALDH-positive cancer stem cells

Targeting ALDH1A1 by disulfiram/copper complex inhibits non-small cell lung cancer recurrence driven by ALDH-positive cancer stem cells

https://doi.org/10.18632/oncotarget.11305

Xinwei Liu, Lihui Wang, Wei Cui, Xiangzhong Yuan, Lulu Lin, Qi Cao, Nannan Wang, Yi Li, Wei Guo, Xun Zhang, Chunfu Wu,  and Jingyu Yang
58516-58530
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Targeting a novel cancer-driving protein (LAPTM4B-35) by a small molecule (ETS) to inhibit cancer growth and metastasis

Targeting a novel cancer-driving protein (LAPTM4B-35) by a small molecule (ETS) to inhibit cancer growth and metastasis

https://doi.org/10.18632/oncotarget.11325

Maojin Li, Rouli Zhou, Yi Shan, Li Li, Lin Wang,  and Gang Liu
58531-58542
Abstract  |  PDF  |  HTML  |  Order a Reprint

Clinical Research Papers

Prognostic significance of preoperative prognostic nutritional index in colorectal cancer: results from a retrospective cohort study and a meta-analysis

Prognostic significance of preoperative prognostic nutritional index in colorectal cancer: results from a retrospective cohort study and a meta-analysis

https://doi.org/10.18632/oncotarget.10148

Yuchong Yang, Peng Gao, Xiaowan Chen, Yongxi Song, Jinxin Shi, Junhua Zhao, Jingxu Sun, Yingying Xu,  and Zhenning Wang
58543-58552
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Randomized clinical trial: Nucleos(t)ide analogues improved survival of CHB-related HCC patients via reducing severity and progression of malignancy

Randomized clinical trial: Nucleos(t)ide analogues improved survival of CHB-related HCC patients via reducing severity and progression of malignancy

https://doi.org/10.18632/oncotarget.10155

Yun Wang, Xiaogang Xiang, Liwen Chen, Zhujun Cao, Rebecca Bao, Huijuan Zhou, Weiliang Tang, Jie Lu, Lanyi Lin, Qing Xie, Shisan Bao,  and Hui Wang
58553-58562
Abstract  |  PDF  |  HTML  |  Order a Reprint

Nuclear localization of B7-H4 in pulmonary adenocarcinomas presenting as a solitary pulmonary nodule

Nuclear localization of B7-H4 in pulmonary adenocarcinomas presenting as a solitary pulmonary nodule

https://doi.org/10.18632/oncotarget.10542

Cheng Chen, Wei-Dong Zhu, Fang Xie,  and Jian-An Huang
58563-58568
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical utility of microRNA-378 as early diagnostic biomarker of human cancers: a meta-analysis of diagnostic test

Clinical utility of microRNA-378 as early diagnostic biomarker of human cancers: a meta-analysis of diagnostic test

https://doi.org/10.18632/oncotarget.10707

Zhan-Zhan Li, Liang-Fang Shen, Yan-Yan Li, Peng Chen,  and Li-Zhang Chen
58569-58578
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Oxaliplatin, 5-fluorouracil and leucovorin (FOLFOX) as second-line therapy for patients with advanced urothelial cancer

Oxaliplatin, 5-fluorouracil and leucovorin (FOLFOX) as second-line therapy for patients with advanced urothelial cancer

https://doi.org/10.18632/oncotarget.10463

Sheng Zhang, Hongxi Xue,  and Qiang Chen
58579-58585
Abstract  |  PDF  |  HTML  |  Order a Reprint

Reviews

Clonal evolution of acute myeloid leukemia highlighted by latest genome sequencing studies

Clonal evolution of acute myeloid leukemia highlighted by latest genome sequencing studies

https://doi.org/10.18632/oncotarget.10850

Xuehong Zhang, Dekang Lv, Yu Zhang, Quentin Liu,  and Zhiguang Li
58586-58594
Abstract  |  PDF  |  HTML  |  Order a Reprint

Anti-miR-203 suppresses ER-positive breast cancer growth and stemness by targeting SOCS3

Anti-miR-203 suppresses ER-positive breast cancer growth and stemness by targeting SOCS3

https://doi.org/10.18632/oncotarget.11193

Naoshad Muhammad, Sourav Bhattacharya, Robert Steele,  and Ratna B. Ray
58595-58605
Abstract  |  PDF  |  HTML  |  Order a Reprint

Diagnostic value of microRNAs in asbestos exposure and malignant mesothelioma: systematic review and qualitative meta-analysis

Diagnostic value of microRNAs in asbestos exposure and malignant mesothelioma: systematic review and qualitative meta-analysis

https://doi.org/10.18632/oncotarget.9686

Luigina Micolucci, Most Mauluda Akhtar, Fabiola Olivieri, Maria Rita Rippo,  and Antonio Domenico Procopio
58606-58637
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Gene mutations and actionable genetic lesions in mantle cell lymphoma

Gene mutations and actionable genetic lesions in mantle cell lymphoma

https://doi.org/10.18632/oncotarget.10716

Makhdum Ahmed, Leo Zhang, Krystle Nomie, Laura Lam,  and Michael Wang
58638-58648
Abstract  |  PDF  |  HTML  |  Order a Reprint

Angiogenesis in pancreatic ductal adenocarcinoma: A controversial issue

Angiogenesis in pancreatic ductal adenocarcinoma: A controversial issue

https://doi.org/10.18632/oncotarget.10765

Vito Longo, Oronzo Brunetti, Antonio Gnoni, Stefano Cascinu, Giampietro Gasparini, Vito Lorusso, Domenico Ribatti,  and Nicola Silvestris
58649-58658
Abstract  |  PDF  |  HTML  |  Order a Reprint

An updated meta-analysis of 37 case-control studies on the association between NFKB1 -94ins/del ATTG promoter polymorphism and cancer susceptibility

An updated meta-analysis of 37 case-control studies on the association between NFKB1 -94ins/del ATTG promoter polymorphism and cancer susceptibility

https://doi.org/10.18632/oncotarget.10808

Yi-Qiao Luo, Duan Wang, Teng Gong,  and Jiang Zhu
58659-58670
Abstract  |  PDF  |  HTML  |  Order a Reprint

Decellularized scaffolds in regenerative medicine

Decellularized scaffolds in regenerative medicine

https://doi.org/10.18632/oncotarget.10945

Yaling Yu, Ali Alkhawaji, Yuqiang Ding,  and Jin Mei
58671-58683
Abstract  |  PDF  |  HTML  |  Order a Reprint

Advanced new strategies for metastatic cancer treatment by therapeutic stem cells and oncolytic virotherapy

Advanced new strategies for metastatic cancer treatment by therapeutic stem cells and oncolytic virotherapy

https://doi.org/10.18632/oncotarget.11017

Geon-Tae Park,  and Kyung-Chul Choi
58684-58695
Abstract  |  PDF  |  HTML  |  Order a Reprint

Cancer diagnostics: The journey from histomorphology to molecular profiling

Cancer diagnostics: The journey from histomorphology to molecular profiling

https://doi.org/10.18632/oncotarget.11061

Atif A. Ahmed,  and Malak Abedalthagafi
58696-58708
Abstract  |  PDF  |  HTML  |  Order a Reprint

Weekly versus three weeks chemotherapy for advanced ovarian cancer: a meta-analysis

Weekly versus three weeks chemotherapy for advanced ovarian cancer: a meta-analysis

https://doi.org/10.18632/oncotarget.11094

Claudia Marchetti, Francesca De Felice, Angela Musella, Innocenza Palaia, Marco Monti, Daniela Musio, Ludovico Muzii, Vincenzo Tombolini,  and Pierluigi Benedetti Panici
58709-58715
Abstract  |  PDF  |  HTML  |  Order a Reprint

Corrections

Correction: Mutation of the BRCA1 SQ-cluster results in aberrant mitosis, reduced homologous recombination, and a compensatory increase in non-homologous end joining

Correction: Mutation of the BRCA1 SQ-cluster results in aberrant mitosis, reduced homologous recombination, and a compensatory increase in non-homologous end joining

https://doi.org/10.18632/oncotarget.11846

Jason M. Beckta, Seth M. Dever, Nisha Gnawali, Ashraf Khalil, Amrita Sule, Sarah E. Golding, Elizabeth Rosenberg, Aarthi Narayanan, Kylene Kehn-Hall, Bo Xu, Lawrence F. Povirk,  and Kristoffer Valerie
58716
Correction  |  PDF


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