Oncotarget

Vol 1, No 5

September 2010

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About The Cover

J124 and J128 have anti-metastatic efficacy in a metastasis model. (a), Livers of mice treated with J124 and J128 as opposed to vehicle alone show distinctive difference in the number of tumor nodules. (b), Representative liver H&E sections of treated and untreated animals underscore differential liver metastasis load. See Schmidt-Kittler et al. (pp. 339-348) and commentary on p. 315-316 of this issue for details.

Table of Contents

Commentaries

P3Kα: A Driver of Tumor Metastasis?

P3Kα: A Driver of Tumor Metastasis?

https://doi.org/10.18632/oncotarget.162

Leigh Zawel
315-316
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The heme oxygenase-1 and c-FLIP in acute myeloid leukemias: two non-redundant but mutually exclusive cellular safeguards protecting cells against TNF-induced cell death?

The heme oxygenase-1 and c-FLIP in acute myeloid leukemias: two non-redundant but mutually exclusive cellular safeguards protecting cells against TNF-induced cell death?

https://doi.org/10.18632/oncotarget.163

Sarah Shirley,  and Olivier Micheau
317-319
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Reviews

Membrane lipids in invadopodia and podosomes: Key structures for cancer invasion and metastasis

Membrane lipids in invadopodia and podosomes: Key structures for cancer invasion and metastasis

https://doi.org/10.18632/oncotarget.164

Hideki Yamaguchi,  and Tsukasa Oikawa
320-328
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Research Papers

CD277 is a negative co-stimulatory molecule universally expressed by ovarian cancer microenvironmental cells

CD277 is a negative co-stimulatory molecule universally expressed by ovarian cancer microenvironmental cells

https://doi.org/10.18632/oncotarget.165

Juan R. Cubillos-Ruiz, Diana Martinez, Uciane K. Scarlett, Melanie R. Rutkowski, Yolanda C. Nesbeth, Ana L. Camposeco-Jacobs,  and Jose R. Conejo-Garcia
329-338
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PI3Kα Inhibitors That Inhibit Metastasis

PI3Kα Inhibitors That Inhibit Metastasis

https://doi.org/10.18632/oncotarget.166

Oleg Schmidt-Kittler, Jiuxiang Zhu, Jian Yang, Guosheng Liu, William Hendricks, Christoph Lengauer, Sandra B. Gabelli, Kenneth W. Kinzler, Bert Vogelstein, David L. Huso,  and Shibin Zhou
339-348
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miR-449a causes Rb-dependent cell cycle arrest and senescence in prostate cancer cells

miR-449a causes Rb-dependent cell cycle arrest and senescence in prostate cancer cells

https://doi.org/10.18632/oncotarget.167

Emily J. Noonan, Robert F. Place, Shashwati Basak, Deepa Pookot,  and Long-Cheng Li
349-358
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FLIP regulation of HO-1 and TNF signalling in human acute myeloid leukemia provides a unique secondary anti-apoptotic mechanism

FLIP regulation of HO-1 and TNF signalling in human acute myeloid leukemia provides a unique secondary anti-apoptotic mechanism

https://doi.org/10.18632/oncotarget.168

Stuart A. Rushworth, Lyubov Zaitseva, Susana Langa, Kristian M. Bowles,  and David J. MacEwan
359-366
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Research Perspectives

What are genome-wide association studies telling us about B-cell tumor development?

What are genome-wide association studies telling us about B-cell tumor development?

https://doi.org/10.18632/oncotarget.169

Amy L. Sherborne,  and Richard S. Houlston
367-372
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Mouse models of hepatocarcinogenesis: What can we learn for the prevention of human hepatocellular carcinoma?

Mouse models of hepatocarcinogenesis: What can we learn for the prevention of human hepatocellular carcinoma?

https://doi.org/10.18632/oncotarget.170

Mihael Vucur, Christoph Roderburg, Kira Bettermann, Frank Tacke, Mathias Heikenwalder, Christian Trautwein,  and Tom Luedde
373-378
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The Siah2-HIF-FoxA2 axis in prostate cancer – new markers and therapeutic opportunities

The Siah2-HIF-FoxA2 axis in prostate cancer – new markers and therapeutic opportunities

https://doi.org/10.18632/oncotarget.171

Jianfei Qi, Maurizio Pellecchia,  and Ze’ev A. Ronai
379-385
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