Suppression of Her2/Neu mammary tumor development in mda-7/IL-24 transgenic mice

Prolonged ovarian hormone deprivation alters the effects of 17β-estradiol on microRNA expression in the aged female rat hypothalamus

Activation of sirtuin 1/3 improves vascular hyporeactivity in severe hemorrhagic shock by alleviation of mitochondrial damage

Loss of Gata4 in Sertoli cells impairs the spermatogonial stem cell niche and causes germ cell exhaustion by attenuating chemokine signaling

Downregulation of RPL15 may predict poor survival and associate with tumor progression in pancreatic ductal adenocarcinoma

Altered microRNA profiles in cerebrospinal fluid exosome in Parkinson disease and Alzheimer disease

Regenerating islet-derived protein 1 inhibits the activation of islet stellate cells isolated from diabetic mice

Lithium increases proliferation of hippocampal neural stem/progenitor cells and rescues irradiation-induced cell cycle arrest in vitro

Adenoid cystic carcinoma: current therapy and potential therapeutic advances based on genomic profiling

Caveolin-1, a stress-related oncotarget, in drug resistance

Tumor-derived exosomes in cancer progression and treatment failure

Cx26 knockout predisposes the mammary gland to primary mammary tumors in a DMBA-induced mouse model of breast cancer

Plasma DCLK1 is a marker of hepatocellular carcinoma (HCC): Targeting DCLK1 prevents HCC tumor xenograft growth via a microRNA-dependent mechanism

Targeting mitochondrial RNA polymerase in acute myeloid leukemia

Characterization of a mantle cell lymphoma cell line resistant to the Chk1 inhibitor PF-00477736

miR-135b suppresses tumorigenesis in glioblastoma stem-like cells impairing proliferation, migration and self-renewal

Wnt2 complements Wnt/β-catenin signaling in colorectal cancer

MicroRNA-21 links epithelial-to-mesenchymal transition and inflammatory signals to confer resistance to neoadjuvant trastuzumab and chemotherapy in HER2-positive breast cancer patients

Targeting metabolic flexibility by simultaneously inhibiting respiratory complex I and lactate generation retards melanoma progression

Arsenic trioxide disrupts glioma stem cells via promoting PML degradation to inhibit tumor growth

Silencing of E2F3 suppresses tumor growth of Her2⁺ breast cancer cells by restricting mitosis

Honokiol inhibits bladder tumor growth by suppressing EZH2/miR-143 axis

Mitochondrial translocation of EGFR regulates mitochondria dynamics and promotes metastasis in NSCLC

Role of cystathionine beta synthase in lipid metabolism in ovarian cancer

Rescuing lymphocytes from HLA-G immunosuppressive effects mediated by the tumor microenvironment

Expression of IL-1α correlates with distant metastasis in patients with head and neck squamous cell carcinoma

SMAC mimetic Debio 1143 synergizes with taxanes, topoisomerase inhibitors and bromodomain inhibitors to impede growth of lung adenocarcinoma cells

Targeting Syndecan-1, a molecule implicated in the process of vasculogenic mimicry, enhances the therapeutic efficacy of the L19-IL2 immunocytokine in human melanoma xenografts

The regulatory mechanisms of myogenin expression in doxorubicin-treated rat cardiomyocytes

MicroRNA-27b, microRNA-101 and microRNA-128 inhibit angiogenesis by down-regulating vascular endothelial growth factor C expression in gastric cancers

Expression and activity of eIF6 trigger Malignant Pleural Mesothelioma growth in vivo

In vivo imaging of therapy response to a novel Pan-HER antibody mixture using FDG and FLT positron emission tomography

Urine BLCA-4 exerts potential role in detecting patients with bladder cancers: a pooled analysis of individual studies

Preclinical model in HCC: the SGK1 kinase inhibitor SI113 blocks tumor progression in vitro and in vivo and synergizes with radiotherapy

Combinatorial TGF-β attenuation with paclitaxel inhibits the epithelial-to-mesenchymal transition and breast cancer stem-like cells

Clinical value of integrated-signature miRNAs in colorectal cancer: miRNA expression profiling analysis and experimental validation

MiR-744 increases tumorigenicity of pancreatic cancer by activating Wnt/β-catenin pathway

Aptamer targeting EGFRvIII mutant hampers its constitutive autophosphorylation and affects migration, invasion and proliferation of glioblastoma cells

OX40 expression enhances the prognostic significance of CD8 positive lymphocyte infiltration in colorectal cancer

Revealing potential molecular targets bridging colitis and colorectal cancer based on multidimensional integration strategy

Small molecule RL71 targets SERCA2 at a novel site in the treatment of human colorectal cancer

High intensity focused ultrasound enhances anti-tumor immunity by inhibiting the negative regulatory effect of miR-134 on CD86 in a murine melanoma model

Acute MUS81 depletion leads to replication fork slowing and a constitutive DNA damage response

Decrease of 5hmC in gastric cancers is associated with TET1 silencing due to with DNA methylation and bivalent histone marks at TET1 CpG island 3′-shore

Molecular profiling of low grade serous ovarian tumours identifies novel candidate driver genes

YK-4-279 effectively antagonizes EWS-FLI1 induced leukemia in a transgenic mouse model

A bladder cancer microenvironment simulation system based on a microfluidic co-culture model

Methionine adenosyltransferase α2 sumoylation positively regulate Bcl-2 expression in human colon and liver cancer cells

Ubiquitin-specific protease 12 interacting partners Uaf-1 and WDR20 are potential therapeutic targets in prostate cancer

Host JDP2 expression in the bone marrow contributes to metastatic spread

SF3A1 and pancreatic cancer: new evidence for the association of the spliceosome and cancer

Application of mitochondrial pyruvate carrier blocker UK5099 creates metabolic reprogram and greater stem-like properties in LnCap prostate cancer cells in vitro

Migration-prone glioma cells show curcumin resistance associated with enhanced expression of miR-21 and invasion/anti-apoptosis-related proteins

Inhibiting bladder tumor growth with a cell penetrating R11 peptide derived from the p53 C-terminus

Reciprocal regulation of Abl kinase by Crk Y251 and Abi1 controls invasive phenotypes in glioblastoma

miR-149 represses metastasis of hepatocellular carcinoma by targeting actin-regulatory proteins PPM1F

Heterogeneity revealed by integrated genomic analysis uncovers a molecular switch in malignant uveal melanoma

JNJ-26481585 primes rhabdomyosarcoma cells for chemotherapeutics by engaging the mitochondrial pathway of apoptosis

miRNA-regulated delivery of lincRNA-p21 suppresses β-catenin signaling and tumorigenicity of colorectal cancer stem cells

The dual topoisomerase inhibitor A35 preferentially and specially targets topoisomerase 2α by enhancing pre-strand and post-strand cleavage and inhibiting DNA religation

Allele frequencies of BRAFV600 mutations in primary melanomas and matched metastases and their relevance for BRAF inhibitor therapy in metastatic melanoma

Usp22 deficiency impairs intestinal epithelial lineage specification in vivo

Endosomal gene expression: a new indicator for prostate cancer patient prognosis?

The novel combination of dual mTOR inhibitor AZD2014 and pan-PIM inhibitor AZD1208 inhibits growth in acute myeloid leukemia via HSF pathway suppression

A combination of tyrosine kinase inhibitors, crizotinib and dasatinib for the treatment of glioblastoma multiforme

Lapatinib increases motility of triple-negative breast cancer cells by decreasing miRNA-7 and inducing Raf-1/MAPK-dependent interleukin-6

SNP-SNP interaction analysis of NF-κB signaling pathway on breast cancer survival

Loss of the epigenetic mark, 5-Hydroxymethylcytosine, correlates with small cell/nevoid subpopulations and assists in microstaging of human melanoma

LncRNA MALAT1 functions as a competing endogenous RNA to regulate ZEB2 expression by sponging miR-200s in clear cell kidney carcinoma

Identification of hallmarks of lung adenocarcinoma prognosis using whole genome sequencing

Polarized cell migration induces cancer type-specific CD133/integrin/Src/Akt/GSK3β/β-catenin signaling required for maintenance of cancer stem cell properties

The impact of RNA binding motif protein 4-regulated splicing cascade on the progression and metabolism of colorectal cancer cells

CDC25A governs proliferation and differentiation of FLT3-ITD acute myeloid leukemia

Bortezomib-mediated down-regulation of telomerase and disruption of telomere homeostasis contributes to apoptosis of malignant cells

Upregulated in Hepatitis B virus-associated hepatocellular carcinoma cells, miR-331-3p promotes proliferation of hepatocellular carcinoma cells by targeting ING5

ZNF32 protects against oxidative stress-induced apoptosis by modulating C1QBP transcription

Suppression of mitochondrial respiration with auraptene inhibits the progression of renal cell carcinoma: involvement of HIF-1α degradation

miR-124 and miR-506 inhibit colorectal cancer progression by targeting DNMT3B and DNMT1

Epigenetic silencing of HIC1 promotes epithelial-mesenchymal transition and drives progression in esophageal squamous cell carcinoma

Molecular profiling of cetuximab and bevacizumab treatment of colorectal tumours reveals perturbations in metabolic and hypoxic response pathways

Subcellular localization of PUMA regulates its pro-apoptotic activity in Burkitt’s lymphoma B cells

Mechanisms linking obesity to altered metabolism in mice colon carcinogenesis

Increased metastasis with loss of E2F2 in Myc-driven tumors

Inhibition of Lyn is a promising treatment for mantle cell lymphoma with bortezomib resistance

Interplay between YB-1 and IL-6 promotes the metastatic phenotype in breast cancer cells

Co-expression of mitosis-regulating genes contributes to malignant progression and prognosis in oligodendrogliomas

MicroRNA-15a/16-1 cluster located at chromosome 13q14 is down-regulated but displays different expression pattern and prognostic significance in multiple myeloma

Traditional Chinese patent medicines for cancer treatment in China: a nationwide medical insurance data analysis

Combining plasma Epstein-Barr virus DNA and nodal maximal standard uptake values of 18F-fluoro-2-deoxy-D-glucose positron emission tomography improved prognostic stratification to predict distant metastasis for locoregionally advanced nasopharyngeal carcinoma

Etoposide enhances antitumor efficacy of MDR1-driven oncolytic adenovirus through autoupregulation of the MDR1 promoter activity

Better survival of renal cell carcinoma in patients with inflammatory bowel disease

Development and validation of a pretreatment prognostic index to predict death and lung metastases in extremity osteosarcoma

The use of personalized biomarkers and liquid biopsies to monitor treatment response and disease recurrence in locally advanced rectal cancer after neoadjuvant chemoradiation

Ideal number of biopsy tumor fragments for predicting HER2 status in gastric carcinoma resection specimens

Treatment outcomes and late toxicities of 869 patients with nasopharyngeal carcinoma treated with definitive intensity modulated radiation therapy: new insight into the value of total dose of cisplatin and radiation boost

Breastfeeding and the incidence of endometrial cancer: A meta-analysis

Plasma fibrinogen levels are correlated with postoperative distant metastasis and prognosis in esophageal squamous cell carcinoma

Distinguishing grade I meningioma from higher grade meningiomas without biopsy

Concurrent radiotherapy with gefitinib in elderly patients with esophageal squamous cell carcinoma: Preliminary results of a phase II study