ENT1 and treatment of viral diseases

Undoing SUMO aids polyQ AR

Cancer metabolism of cone photoreceptors

Inheritance in MGUS and MM

Stathmin drives virus-induced metastasis

Armt1: a phoenix rises from the ashes

Hsp70 proteins in mitosis and disease

MicroRNAs, T follicular helper cells and inflammaging

IL-11 in multiple sclerosis

The negative NK cell maturation checkpoint Foxo1

Pathogenic Th2 (Tpath2) cells in airway inflammation

The flavors of plasma cells

Adenosine: a selfish-immunity signal?

PTX3 acts as an extrinsic oncosuppressor

Tuning B cell responsiveness by antigen receptor isotype

EFTUD2 on innate immunity

Immunosuppressive arenaviral exoribonuclease

Caspase 3 in dying tumor cells mediates post-irradiation angiogenesis

Functional signaling pathway analysis of lung adenocarcinomas identifies novel therapeutic targets for KRAS mutant tumors

Direct inhibition of c-Myc-Max heterodimers by celastrol and celastrol-inspired triterpenoids

Common cancer-associated imbalances in the DNA damage response confer sensitivity to single agent ATR inhibition

Antigen spreading-induced CD8⁺T cells confer protection against the lethal challenge of wild-type malignant mesothelioma by eliminating myeloid-derived suppressor cells

Bortezomib enhances expression of effector molecules in anti-tumor CD8⁺ T lymphocytes by promoting Notch-nuclear factor-κB crosstalk

Lack of intracellular replication of M. tuberculosis and M. bovis BCG caused by delivering bacilli to lysosomes in murine brain microvascular endothelial cells

Piperine metabolically regulates peritoneal resident macrophages to potentiate their functions against bacterial infection

Nodal metastasis in cervical cancer occurs in clearly delineated fields of immune suppression in the pelvic lymph catchment area

DNA-mediated adjuvant immunotherapy extends survival in two different mouse models of myeloid malignancies

MicroRNAs as prognostic molecular signatures in renal cell carcinoma: a systematic review and meta-analysis

An integrative approach for the identification of prognostic and predictive biomarkers in rectal cancer

EMMPRIN regulates tumor growth and metastasis by recruiting bone marrow-derived cells through paracrine signaling of SDF-1 and VEGF

MicroRNA-506 suppresses tumor proliferation and metastasis in colon cancer by directly targeting the oncogene EZH2

Molecular inimitability amongst tumors: implications for precision cancer medicine in the age of personalized oncology

TQ inhibits hepatocellular carcinoma growth in vitro and in vivo via repression of Notch signaling

Acquired resistance to 5-fluorouracil via HSP90/Src-mediated increase in thymidylate synthase expression in colon cancer

Normal mammary epithelial cells promote carcinoma basement membrane invasion by inducing microtubule-rich protrusions

Acquisition of a single EZH2 D1 domain mutation confers acquired resistance to EZH2-targeted inhibitors

p62/IMP2 stimulates cell migration and reduces cell adhesion in breast cancer

A CD21 low phenotype, with no evidence of autoantibodies to complement proteins, is consistent with a poor prognosis in CLL

A nanostructure of functional targeting epirubicin liposomes dually modified with aminophenyl glucose and cyclic pentapeptide used for brain glioblastoma treatment

MiR-373 drives the epithelial-to-mesenchymal transition and metastasis via the miR-373-TXNIP-HIF1α-TWIST signaling axis in breast cancer

PDGF activation in PGDS-positive arachnoid cells induces meningioma formation in mice promoting tumor progression in combination with Nf2 and Cdkn2ab loss

RhoGDI deficiency induces constitutive activation of Rho GTPases and COX-2 pathways in association with breast cancer progression

MicroRNA-99a inhibits tumor aggressive phenotypes through regulating HOXA1 in breast cancer cells

Glucose transporter isoform 1 expression enhances metastasis of malignant melanoma cells

Flcn-deficient renal cells are tumorigenic and sensitive to mTOR suppression

miR-134 in extracellular vesicles reduces triple-negative breast cancer aggression and increases drug sensitivity

Synergistic anticancer effects of triptolide and celastrol, two main compounds from thunder god vine

MiR-200b regulates autophagy associated with chemoresistance in human lung adenocarcinoma

Down-regulation of the Lamin A/C in neuroblastoma triggers the expansion of tumor initiating cells

Suppressor of Ty homolog-5, a novel tumor-specific human telomerase reverse transcriptase promoter-binding protein and activator in colon cancer cells

Antitumoral activity of the mithralog EC-8042 in triple negative breast cancer linked to cell cycle arrest in G2

Circulating microRNA signature as liquid-biopsy to monitor lung cancer in low-dose computed tomography screening

Integrated miRNA profiling and bioinformatics analyses reveal potential causative miRNAs in gastric adenocarcinoma

LYAR promotes colorectal cancer cell mobility by activating galectin-1 expression

IL-13 receptor α2 is a negative prognostic factor in human lung cancer and stimulates lung cancer growth in mice

Na_v1.5 regulates breast tumor growth and metastatic dissemination in vivo

Metformin and temozolomide act synergistically to inhibit growth of glioma cells and glioma stem cells in vitro and in vivo

MiR-208a stimulates the cocktail of SOX2 and β-catenin to inhibit the let-7 induction of self-renewal repression of breast cancer stem cells and formed miR208a/let-7 feedback loop via LIN28 and DICER1

Deciphering the molecular basis of invasiveness in Sdhb-deficient cells

IL-17 producing mast cells promote the expansion of myeloid-derived suppressor cells in a mouse allergy model of colorectal cancer

Immature myeloid progenitors promote disease progression in a mouse model of Barrett’s-like metaplasia

Twist1-mediated 4E-BP1 regulation through mTOR in non-small cell lung cancer

PD-L1 is remarkably over-expressed in EBV-associated pulmonary lymphoepithelioma-like carcinoma and related to poor disease-free survival

Breast cancer associated a2 isoform vacuolar ATPase immunomodulates neutrophils: potential role in tumor progression

Repurposing the anti-malarial drug artesunate as a novel therapeutic agent for metastatic renal cell carcinoma due to its attenuation of tumor growth, metastasis, and angiogenesis

Lysine-specific demethylase 1 promotes tumorigenesis and predicts prognosis in gallbladder cancer

Down-regulation of IKKβ expression in glioma-infiltrating microglia/macrophages is associated with defective inflammatory/immune gene responses in glioblastoma

Sur8/Shoc2 promotes cell motility and metastasis through activation of Ras-PI3K signaling

Inhibiting NFAT1 for breast cancer therapy: New insights into the mechanism of action of MDM2 inhibitor JapA

Isolation and characterization of novel RECK tumor suppressor gene splice variants

t-Darpp overexpression in HER2-positive breast cancer confers a survival advantage in lapatinib

Role of the short isoform of the progesterone receptor in breast cancer cell invasiveness at estrogen and progesterone levels in the pre- and post-menopausal ranges

Vesicular stomatitis virus expressing interferon-β is oncolytic and promotes antitumor immune responses in a syngeneic murine model of non-small cell lung cancer

p73 regulates basal and starvation-induced liver metabolism in vivo

Extracting tumor tissue immune status from expression profiles: correlating renal cancer prognosis with tumor-associated immunome

Pre-clinical evidence of PIM kinase inhibitor activity in BCR-ABL1 unmutated and mutated Philadelphia chromosome-positive (Ph+) leukemias

High frequency of additional gene mutations in acute myeloid leukemia with MLL partial tandem duplication: DNMT3A mutation is associated with poor prognosis

Cigarette side-stream smoke lung and bladder carcinogenesis: inducing mutagenic acrolein-DNA adducts, inhibiting DNA repair and enhancing anchorage-independent-growth cell transformation

An epigenetic auto-feedback loop regulates TGF-β type II receptor expression and function in NSCLC

A common promoter hypomethylation signature in invasive breast, liver and prostate cancer cell lines reveals novel targets involved in cancer invasiveness

Targeting of RUNX3 by miR-130a and miR-495 cooperatively increases cell proliferation and tumor angiogenesis in gastric cancer cells

Inhibition of BMK1 pathway suppresses cancer stem cells through BNIP3 and BNIP3L

Simultaneous targeting of 5-LOX-COX and EGFR blocks progression of pancreatic ductal adenocarcinoma

Contrasting breast cancer molecular subtypes across serial tumor progression stages: biological and prognostic implications

Genomic landscape of endometrial stromal sarcoma of uterus

Depletion of mucin in mucin-producing human gastrointestinal carcinoma: Results from in vitro and in vivo studies with bromelain and N-acetylcysteine

Liver X receptor reduces proliferation of human oral cancer cells by promoting cholesterol efflux via up-regulation of ABCA1 expression

The NEXT-1 (Next generation pErsonalized tX with mulTi-omics and preclinical model) trial: prospective molecular screening trial of metastatic solid cancer patients, a feasibility analysis

Lowered circulating aspartate is a metabolic feature of human breast cancer

Non-thermal plasma induces AKT degradation through turn-on the MUL1 E3 ligase in head and neck cancer

BRD4-targeted therapy induces Myc-independent cytotoxicity in Gnaq/11-mutatant uveal melanoma cells

T-LAK cell-originated protein kinase presents a novel therapeutic target in FLT3-ITD mutated acute myeloid leukemia

Role of N-cadherin in proliferation, migration, and invasion of germ cell tumours

Cranberry proanthocyanidins inhibit esophageal adenocarcinoma in vitro and in vivo through pleiotropic cell death induction and PI3K/AKT/mTOR inactivation

Expression profile of innate immune receptors, NLRs and AIM2, in human colorectal cancer: correlation with cancer stages and inflammasome components

Silencing NKD2 by promoter region hypermethylation promotes gastric cancer invasion and metastasis by up-regulating SOX18 in human gastric cancer

CD19⁺CD24^hiCD38^hiBregs involved in downregulate helper T cells and upregulate regulatory T cells in gastric cancer

Prostaglandin E receptor 4 (EP4) promotes colonic tumorigenesis

MT1-MMP dependent repression of the tumor suppressor SPRY4 contributes to MT1-MMP driven melanoma cell motility

Golgi protein 73 activation of MMP-13 promotes hepatocellular carcinoma cell invasion

Targeting the membrane-anchored serine protease testisin with a novel engineered anthrax toxin prodrug to kill tumor cells and reduce tumor burden

The NF-κB p65/miR-23a-27a-24 cluster is a target for leukemia treatment

Effective impairment of myeloma cells and their progenitors by blockade of monocarboxylate transportation

Long noncoding RNA HOXA-AS2 promotes gastric cancer proliferation by epigenetically silencing P21/PLK3/DDIT3 expression

The pan-HER family tyrosine kinase inhibitor afatinib overcomes HER3 ligand heregulin-mediated resistance to EGFR inhibitors in non-small cell lung cancer

The hypomethylating agent decitabine prior to chemotherapy improves the therapy efficacy in refractory/relapsed acute myeloid leukemia patients

Induction of USP17 by combining BET and HDAC inhibitors in breast cancer cells

SIP1 is a downstream effector of GADD45G in senescence induction and growth inhibition of liver tumor cells

GLI1 orchestrates CXCR4/CXCR7 signaling to enhance migration and metastasis of breast cancer cells

GRP78 confers the resistance to 5-FU by activating the c-Src/LSF/TS Axis in hepatocellular carcinoma

Heme oxygenase-1 in macrophages controls prostate cancer progression

Differential susceptibility to colorectal cancer due to naturally occurring gut microbiota

HSulf-1 deficiency dictates a metabolic reprograming of glycolysis and TCA cycle in ovarian cancer

Targeting EZH2 regulates tumor growth and apoptosis through modulating mitochondria dependent cell-death pathway in HNSCC

Imaging of carbonic anhydrase IX with an ¹¹¹In-labeled dual-motif inhibitor

AR-v7 protein expression is regulated by protein kinase and phosphatase

Apoptosis induced by temozolomide and nimustine in glioblastoma cells is supported by JNK/c-Jun-mediated induction of the BH3-only protein BIM

Pyrvinium selectively targets blast phase-chronic myeloid leukemia through inhibition of mitochondrial respiration

Dendritic cell vaccination with a toll-like receptor agonist derived from mycobacteria enhances anti-tumor immunity

HBx-related long non-coding RNA DBH-AS1 promotes cell proliferation and survival by activating MAPK signaling in hepatocellular carcinoma

MUC4-promoted neural invasion is mediated by the axon guidance factor netrin-1 in PDAC

Differential expression and biochemical activity of the immune receptor Tim-3 in healthy and malignant human myeloid cells

The association between let-7, RAS and HIF-1α in Ewing Sarcoma tumor growth

Primary CNS lymphoproliferative disease, mycophenolate and calcineurin inhibitor usage

EGFRvIII does not affect radiosensitivity with or without gefitinib treatment in glioblastoma cells

BPTF promotes tumor growth and predicts poor prognosis in lung adenocarcinomas

The metastasis suppressor, NDRG1, inhibits “stemness” of colorectal cancer via down-regulation of nuclear β-catenin and CD44

The value of forceps biopsy and core needle biopsy in prediction of pathologic complete remission in locally advanced rectal cancer treated with neoadjuvant chemoradiotherapy

The efficacy and safety of Endostar combined with chemoradiotherapy for patients with advanced, locally recurrent nasopharyngeal carcinoma

Comparison of survival and clinicopathologic features in colorectal cancer among African American, Caucasian, and Chinese patients treated in the United States: Results from the surveillance epidemiology and end results (SEER) database

Effects of first- and second-generation tyrosine kinase inhibitor therapy on glucose and lipid metabolism in chronic myeloid leukemia patients: a real clinical problem?

Reducing the probability of radiation-induced hepatic toxicity by changing the treatment modality from helical tomotherapy to fixed-beam intensity-modulated radiotherapy

Efficiency of CD19 chimeric antigen receptor-modified T cells for treatment of B cell malignancies in phase I clinical trials: a meta-analysis

High PD-L1 expression was associated with poor prognosis in 870 Chinese patients with breast cancer

Prognostic clinical factors in pretreated colorectal cancer patients receiving regorafenib: implications for clinical management.

RET mutation p.S891A in a Chinese family with familial medullary thyroid carcinoma and associated cutaneous amyloidosis binding OSMR variant p.G513D

Changes in expression levels of ERCC1, DPYD, and VEGFA mRNA after first-line chemotherapy of metastatic colorectal cancer: results of a multicenter study

KRAS mutations affect prognosis of non-small-cell lung cancer patients treated with first-line platinum containing chemotherapy

Association of FGFR3 and FGFR4 gene polymorphisms with breast cancer in Chinese women of Heilongjiang province