Oncotarget

Vol 1, No 3

July 2010

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About The Cover

Src tyrosine kinase increases Robo1 at the plasma membrane in an Abl kinase dependent manner to promote tumor cell migration. An immunofluorescence image of endogenous Robo1 at the plasma membrane of Src transformed cells is shown. See Khusial et al (pp. 198-209) and commentary on p. 167 of this issue for details.

Table of Contents

Commentaries

POLQ in Breast Cancer

POLQ in Breast Cancer

https://doi.org/10.18632/oncotarget.120

Adrian Begg
161-162
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Phosphatidylcholine metabolic transformation and progression signature as a pharmacodynamic biomarker

Phosphatidylcholine metabolic transformation and progression signature as a pharmacodynamic biomarker

https://doi.org/10.18632/oncotarget.121

Eric O. Aboagye
163-166
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Src and Abl hijack the Robo1 pathway

Src and Abl hijack the Robo1 pathway

https://doi.org/10.18632/oncotarget.122

Christian Naus
167-167
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Reviews

Prognostic impact of the MDM2SNP309 Allele in Leukemia and Lymphoma

Prognostic impact of the MDM2SNP309 Allele in Leukemia and Lymphoma

https://doi.org/10.18632/oncotarget.123

Sean M. Post, Vinod Pant, Hussein Abbas,  and Alfonso Quintás-Cardama
168-174
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Research Papers

Overexpression of POLQ Confers a Poor Prognosis in Early Breast Cancer Patients

Overexpression of POLQ Confers a Poor Prognosis in Early Breast Cancer Patients

https://doi.org/10.18632/oncotarget.124

Geoff S. Higgins, Adrian L. Harris, Remko Prevo, Thomas Helleday, W Gillies McKenna,  and Francesca M. Buffa
175-184
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Modulation of melanoma cell phospholipid metabolism in response to heat shock protein 90 inhibition

Modulation of melanoma cell phospholipid metabolism in response to heat shock protein 90 inhibition

https://doi.org/10.18632/oncotarget.125

Mounia Beloueche-Babari, Vaitha Arunan, L. Elizabeth Jackson, Nina Perusinghe, Swee Y. Sharp, Paul Workman,  and Martin O. Leach
185-197
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Src activates Abl to augment Robo1 expression in order to promote tumor cell migration

Src activates Abl to augment Robo1 expression in order to promote tumor cell migration

https://doi.org/10.18632/oncotarget.126

P. Raaj Khusial, Bhaskar Vadla, Harini Krishnan, Trudy F. Ramlall, Yongquan Shen, Hitoshi Ichikawa, Jian-Guo Geng,  and Gary S. Goldberg
198-209
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Jagged1 expression regulated by Notch3 and Wnt/β-catenin signaling pathways in ovarian cancer

Jagged1 expression regulated by Notch3 and Wnt/β-catenin signaling pathways in ovarian cancer

https://doi.org/10.18632/oncotarget.127

Xu Chen, Alexander Stoeck, Soo Jung Lee, Ie-Ming Shih, Michael M. Wang,  and Tian-Li Wang
210-218
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Research Perspectives

PEAK1, a Novel Kinase Target in the Fight Against Cancer

PEAK1, a Novel Kinase Target in the Fight Against Cancer

https://doi.org/10.18632/oncotarget.128

Jonathan A. Kelber,  and Richard L. Klemke
219-223
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Is miR-29 an oncogene or tumor suppressor in CLL?

Is miR-29 an oncogene or tumor suppressor in CLL?

https://doi.org/10.18632/oncotarget.129

Yuri Pekarsky,  and Carlo M. Croce
224-227
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Targeting Rb mutant cancers by inactivating TSC2

Targeting Rb mutant cancers by inactivating TSC2

https://doi.org/10.18632/oncotarget.130

Jennifer S. Searle, Binghui Li,  and Wei Du
228-232
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