ATM/MAPK7 crosstalk in cancer

Cancer suppression by systemic inactivation of p38MAPK

Dimethyl fumarate for ischemic stroke

Pravastatin activates activator protein 2 alpha to augment the angiotensin II-induced abdominal aortic aneurysms

Neutralization of interleukin-9 ameliorates symptoms of allergic rhinitis by reducing Th2, Th9, and Th17 responses and increasing the Treg response in a murine model

Epithelial membrane protein 3 regulates TGF-β signaling activation in CD44-high glioblastoma

Musashi2 promotes the development and progression of pancreatic cancer by down-regulating Numb protein

Probing the prostate tumour microenvironment I: impact of glucose deprivation on a cell model of prostate cancer progression

Detection of phosphatidylserine-positive exosomes as a diagnostic marker for ovarian malignancies: a proof of concept study

Prognostic value of the neutrophil-to-lymphocyte ratio in the ARQ 197-215 second-line study for advanced hepatocellular carcinoma

Distinct patterns of infiltrating CD8+ T cells in HPV+ and CD68 macrophages in HPV- oropharyngeal squamous cell carcinomas are associated with better clinical outcome but PD-L1 expression is not prognostic

Ladarixin, a dual CXCR1/2 inhibitor, attenuates experimental melanomas harboring different molecular defects by affecting malignant cells and tumor microenvironment

Nuclear transport of cancer extracellular vesicle-derived biomaterials through nuclear envelope invagination-associated late endosomes

The ribosomal protein gene RPL5 is a haploinsufficient tumor suppressor in multiple cancer types

Long non-coding RNA SPRY4-IT1 pormotes colorectal cancer metastasis by regulate epithelial-mesenchymal transition

IκB-Kinase-epsilon (IKKε) over-expression promotes the growth of prostate cancer through the C/EBP-β dependent activation of IL-6 gene expression

KLK6 proteolysis is implicated in the turnover and uptake of extracellular alpha-synuclein species

Impact of diabetes on the risk of bedsore in patients undergoing surgery: an updated quantitative analysis of cohort studies

Loss of maternal chromosome 11 is a signature event in SDHAF2, SDHD, and VHL-related paragangliomas, but less significant in SDHB-related paragangliomas

Transcription factor HBP1 is a direct anti-cancer target of transcription factor FOXO1 in invasive oral cancer

Tianfoshen oral liquid: a CFDA approved clinical traditional Chinese medicine, normalizes major cellular pathways disordered during colorectal carcinogenesis

Increased incidence of ectopic pregnancy after in vitro fertilization in women with decreased ovarian reserve

Transdifferentiation of human male germline stem cells to hepatocytes in vivo via the transplantation under renal capsules

Tolfenamic acid-induced alterations in genes and pathways in pancreatic cancer cells

Inactivation of CK1α in multiple myeloma empowers drug cytotoxicity by affecting AKT and β-catenin survival signaling pathways

Genomic characteristics of pancreatic squamous cell carcinoma, an investigation by using high throughput sequencing after in-solution hybrid capture

The association of two polymorphisms in adiponectin-encoding gene with hypertension risk and the changes of circulating adiponectin and blood pressure: A meta-analysis

Allergies and risk of colorectal cancer: a systematic review and meta-analysis of observational studies

Chemotherapy-mediated miR-29b expression inhibits the invasion and angiogenesis of cervical cancer

Valproic acid inhibits glioblastoma multiforme cell growth via paraoxonase 2 expression

Cytoprotective effect of chlorogenic acid against hydrogen peroxide-induced oxidative stress in MC3T3-E1 cells through PI3K/Akt-mediated Nrf2/HO-1 signaling pathway

MicroRNA-744 promotes prostate cancer progression through aberrantly activating Wnt/β-catenin signaling

Transcriptional suppression of microRNA-27a contributes to laryngeal cancer differentiation via GSK-3β-involved Wnt/β-catenin pathway

MAGE expression in head and neck squamous cell carcinoma primary tumors, lymph node metastases and respective recurrences-implications for immunotherapy

AMPK-autophagy inhibition sensitizes icaritin-induced anti-colorectal cancer cell activity

A new HDAC inhibitor cinnamoylphenazine shows antitumor activity in association with intensive macropinocytosis

Clinicopathological significance of intratumoral and peritumoral lymphocytes and lymphocyte score based on the histologic subtypes of cutaneous melanoma

Matched-pair analysis of survival in patients with poorly differentiated versus well-differentiated glottic squamous cell carcinoma

E2F-1 targets miR-519d to regulate the expression of the ras homolog gene family member C

Detection of CCNE1/URI (19q12) amplification by in situ hybridisation is common in high grade and type II endometrial cancer

hPaf1/PD2 interacts with OCT3/4 to promote self-renewal of ovarian cancer stem cells

A methodological study of genome-wide DNA methylation analyses using matched archival formalin-fixed paraffin embedded and fresh frozen breast tumors

The conformational changes of Zika virus methyltransferase upon converting SAM to SAH

MEK inhibition is a promising therapeutic strategy for MLL-rearranged infant acute lymphoblastic leukemia patients carrying RAS mutations

Nuclear PRMT5, cyclin D1 and IL-6 are associated with poor outcome in oropharyngeal squamous cell carcinoma patients and is inversely associated with p16-status

Disabled cell density sensing leads to dysregulated cholesterol synthesis in glioblastoma

A novel seven-long non-coding RNA signature predicts survival in early stage lung adenocarcinoma

MiR-155-5p positively regulates CCL17-induced colon cancer cell migration by targeting RhoA

Cyclin E overexpression as a biomarker for combination treatment strategies in inflammatory breast cancer

Tenovin-6 inhibits proliferation and survival of diffuse large B-cell lymphoma cells by blocking autophagy

Molecularly targeted co-delivery of a histone deacetylase inhibitor and paclitaxel by lipid-protein hybrid nanoparticles for synergistic combinational chemotherapy

The homeoprotein Dlx5 drives murine T-cell lymphomagenesis by directly transactivating Notch and upregulating Akt signaling

Intratumoral heterogeneity of intrahepatic cholangiocarcinoma

The impact of intratumoral metabolic heterogeneity on postoperative recurrence and survival in resectable esophageal squamous cell carcinoma

Activation of Akt by SC79 protects myocardiocytes from oxygen and glucose deprivation (OGD)/re-oxygenation

High level of viral microRNA-BART20-5p expression is associated with worse survival of patients with Epstein-Barr virus-associated gastric cancer

Prognostic role of N-Acetylgalactosaminyltransferase 10 in metastatic renal cell carcinoma

Prognostic significance of positive peritoneal cytology in resectable pancreatic cancer: a systemic review and meta-analysis

Acquired resistance to LY2874455 in FGFR2-amplified gastric cancer through an emergence of novel FGFR2-ACSL5 fusion

Epidermal growth factor receptor (EGFR) mutations in non-small cell lung cancer (NSCLC) of Yunnan in southwestern China

Targeted breast cancer therapy by harnessing the inherent blood group antigen immune system

Effects of antiviral therapy on post-hepatectomy HBV reactivation and liver function in HBV DNA-negative patients with HBV-related hepatocellular carcinoma

Peroxiredoxin 2 is associated with colorectal cancer progression and poor survival of patients

Epigenetic silencing of XAF1 in high-grade gliomas is associated with IDH1 status and improved clinical outcome

Boosting the hypoxic response in myeloid cells accelerates resolution of fibrosis and regeneration of the liver in mice

Comparing the long-term efficacy of standard and combined minimally invasive procedures for unresectable HCC: a mixed treatment comparison

SETD6 regulates NF-κB signaling in urothelial cell survival: Implications for bladder cancer

Association of plasma ghrelin levels and ghrelin rs4684677 polymorphism with mild cognitive impairment in type 2 diabetic patients

Genome-wide DNA copy number analysis in clonally expanded human ovarian cancer cells with distinct invasive/migratory capacities

Germacrone derivatives: synthesis, biological activity, molecular docking studies and molecular dynamics simulations

The prognostic relevance of primary tumor location in patients undergoing resection for pancreatic ductal adenocarcinoma

Colorectal cancer cells suppress CD4⁺ T cells immunity through canonical Wnt signaling

High-dose radiotherapy is associated with better local control of bone metastasis from hepatocellular carcinoma

Factors associated with ethnical disparity in overall survival for patients with hepatocellular carcinoma

Regulation of hepatic pyruvate dehydrogenase phosphorylation in offspring glucose intolerance induced by intrauterine hyperglycemia

CX3CL1: a potential chemokine widely involved in the process spinal metastases

Up-regulation of tumor suppressor genes by exogenous dhC16-Cer contributes to its anti-cancer activity in primary effusion lymphoma

Plumbagin restrains hepatocellular carcinoma angiogenesis by suppressing the migration and invasion of tumor-derived vascular endothelial cells

Posttranscriptional regulation of Galectin-3 by miR-128 contributes to colorectal cancer progression

Selective extracellular vesicle exclusion of miR-142-3p by oral cancer cells promotes both internal and extracellular malignant phenotypes

Ex vivo 2D and 3D HSV-2 infection model using human normal vaginal epithelial cells

Relationship between LINC00341 expression and cancer prognosis

Integrative miRNA and mRNA analysis in penile carcinomas reveals markers and pathways with potential clinical impact

Probing the prostate tumour microenvironment II: Impact of hypoxia on a cell model of prostate cancer progression

Tumor-associated NADH oxidase (tNOX)-NAD⁺-sirtuin 1 axis contributes to oxaliplatin-induced apoptosis of gastric cancer cells

Integrative computational analysis of transcriptional and epigenetic alterations implicates DTX1 as a putative tumor suppressor gene in HNSCC

FM807, a curcumin analogue, shows potent antitumor effects in nasopharyngeal carcinoma cells by heat shock protein 90 inhibition

Hyperhomocysteinemia results from and promotes hepatocellular carcinoma via CYP450 metabolism by CYP2J2 DNA methylation

Silence of cancer susceptibility candidate 9 inhibits gastric cancer and reverses chemoresistance

Elevated NF-κB signaling in Asherman syndrome patients and animal models

uPAR-targeted optical near-infrared (NIR) fluorescence imaging and PET for image-guided surgery in head and neck cancer: proof-of-concept in orthotopic xenograft model

Increased autophagy in fibroblast-like synoviocytes leads to immune enhancement potential in rheumatoid arthritis

Promoter methylation of MCAM, ERα and ERβ in serum of early stage prostate cancer patients

L1 increases adhesion-mediated proliferation and chemoresistance of retinoblastoma

LncSubpathway: a novel approach for identifying dysfunctional subpathways associated with risk lncRNAs by integrating lncRNA and mRNA expression profiles and pathway topologies

Characteristics of Chinese herbal medicine usage in ischemic heart disease patients among type 2 diabetes and their protection against hydrogen peroxide-mediated apoptosis in H9C2 cardiomyoblasts

Bigh3 silencing increases retinoblastoma tumor growth in the murine SV40-TAg-Rb model

In vivo and in vitro effects of microRNA-27a on proliferation, migration and invasion of breast cancer cells through targeting of SFRP1 gene via Wnt/β-catenin signaling pathway

The nitrobenzoxadiazole derivative MC3181 blocks melanoma invasion and metastasis

Tunneling nanotubes promote intercellular mitochondria transfer followed by increased invasiveness in bladder cancer cells

Kalirin and CHD7: novel endothelial dysfunction indicators in circulating extracellular vesicles from hypertensive patients with albuminuria

Hyaluronan synthase 3 mediated oncogenic action through forming inter-regulation loop with tumor necrosis factor alpha in oral cancer

The combination of PD-L1 expression and decreased tumor-infiltrating lymphocytes is associated with a poor prognosis in triple-negative breast cancer

Differential expression of CD44 and CD24 markers discriminates the epitheliod from the fibroblastoid subset in a sarcomatoid renal carcinoma cell line: evidence suggesting the existence of cancer stem cells in both subsets as studied with sorted cells

Combined evaluation of the FAS cell surface death receptor and CD8+ tumor infiltrating lymphocytes as a prognostic biomarker in breast cancer

The prognostic value of tumor-infiltrating T lymphocytes in ovarian cancer

Prognostic value of combination of preoperative platelet count and mean platelet volume in patients with resectable non-small cell lung cancer

Mean cerebral blood volume is an effective diagnostic index of recurrent and radiation injury in glioma patients: A meta-analysis of diagnostic test

Detection fidelity of AR mutations in plasma derived cell-free DNA

Klotho suppresses the inflammatory responses and ameliorates cardiac dysfunction in aging endotoxemic mice

Propiece IL-1α facilitates the growth of acute T-lymphocytic leukemia cells through the activation of NF-κB and SP1

TNFAIP8 interacts with LATS1 and promotes aggressiveness through regulation of Hippo pathway in hepatocellular carcinoma

Novel HBsAg mutations correlate with hepatocellular carcinoma, hamper HBsAg secretion and promote cell proliferation in vitro

A long term, non-tumorigenic rat hepatocyte cell line and its malignant counterpart, as tools to study hepatocarcinogenesis

SerpinB3 upregulates the Cyclooxygenase-2 / β-Catenin positive loop in colorectal cancer

Stromal fibroblasts present in breast carcinomas promote tumor growth and angiogenesis through adrenomedullin secretion

STAT3 is required for MiR-17-5p-mediated sensitization to chemotherapy-induced apoptosis in breast cancer cells

Stathmin decreases cholangiocarcinoma cell line sensitivity to staurosporine-triggered apoptosis via the induction of ERK and Akt signaling

CHL1 hypermethylation as a potential biomarker of poor prognosis in breast cancer

Liver X receptors agonist GW3965 re-sensitizes gefitinib-resistant human non-small cell lung cancer cell to gefitinib treatment by inhibiting NF-κB in vitro

Significant prognostic value of circulating tumor cells in esophageal cancer patients: A meta-analysis

PLK1 inhibition enhances temozolomide efficacy in IDH1 mutant gliomas

Association between single nucleotide variants of vascular endothelial growth factor A and the risk of thyroid carcinoma and nodular goiter in a Han Chinese population

The lack of the organic cation transporter OCT1 at the plasma membrane of tumor cells precludes a positive response to sorafenib in patients with hepatocellular carcinoma

Prime-boost immunization by both DNA vaccine and oncolytic adenovirus expressing GM-CSF and shRNA of TGF-β2 induces anti-tumor immune activation

Identification of distinct molecular subtypes of uterine carcinosarcoma

Novel polymorphism in FADS1 gene and fish consumption on risk of oral cancer: A case-control study in southeast China

PD-L1 up-regulation in melanoma increases disease aggressiveness and is mediated through miR-17-5p

A phase II open-label multicenter study of gefitinib in combination with irradiation followed by chemotherapy in patients with inoperable stage III non-small cell lung cancer

Application of intensity-modulated radiotherapy in unresectable poorly differentiated thyroid carcinoma

A randomized, phase II study of gefitinib alone versus nimotuzumab plus gefitinib after platinum-based chemotherapy in advanced non-small cell lung cancer (KCSG LU12-01)

Safety and efficacy of bleomycin/pingyangmycin-containing chemotherapy regimens for malignant germ cell tumor patients in the female genital system

TLE1 function and therapeutic potential in cancer

Cold atmospheric plasma, a novel promising anti-cancer treatment modality

Inhibition of cancer antioxidant defense by natural compounds

Metformin therapy and risk of colorectal adenomas and colorectal cancer in type 2 diabetes mellitus patients: A systematic review and meta-analysis

Prognostic value of RDW in cancers: a systematic review and meta-analysis

The association between copper transporters and the prognosis of cancer patients undergoing chemotherapy: a meta-analysis of literatures and datasets

Inhibition of the fibroblast growth factor receptor (FGFR) pathway: the current landscape and barriers to clinical application

The role of long non-coding RNAs in nasopharyngeal carcinoma: As systemic review

The Hippo signaling pathway provides novel anti-cancer drug targets