Aryl hydrocarbon receptor nuclear translocator (ARNT) isoforms control lymphoid cancer cell proliferation through differentially regulating tumor suppressor p53 activity

MicroRNA dysregulation and esophageal cancer development depend on the extent of zinc dietary deficiency

MPL W515L expression induces TGFβ secretion and leads to an increase in chemokinesis via phosphorylation of THOC5

DNA methylation in PRDM8 is indicative for dyskeratosis congenita

Metformin regulates oxLDL-facilitated endothelial dysfunction by modulation of SIRT1 through repressing LOX-1-modulated oxidative signaling

Identity, proliferation capacity, genomic stability and novel senescence markers of mesenchymal stem cells isolated from low volume of human bone marrow

Identification of long non-coding RNAs as novel biomarker and potential therapeutic target for atrial fibrillation in old adults

Stress resistance and lifespan are increased in C. elegans but decreased in S. cerevisiae by mafr-1/maf1 deletion

Targeting c-fms kinase attenuates chronic aristolochic acid nephropathy in mice

An efficient model of human endometriosis by induced unopposed estrogenicity in baboons

miR-19b attenuates H₂O₂-induced apoptosis in rat H9C2 cardiomyocytes via targeting PTEN

Acidic leucine-rich nuclear phosphoprotein-32A (ANP32A) association with lymph node metastasis predicts poor survival in oral squamous cell carcinoma patients

Immunogenicity and safety of xenogeneic vascular endothelial growth factor receptor-2 DNA vaccination in mice and dogs

First in-depth analysis of the novel Th2-type cytokines in salmonid fish reveals distinct patterns of expression and modulation but overlapping bioactivities

Compensatory roles of CD8⁺ T cells and plasmacytoid dendritic cells in gut immune regulation for reduced function of CD4⁺ Tregs

Removal of regulatory T cells prevents secondary chronic infection but increases the mortality of subsequent sub-acute infection in sepsis mice

Epigenetic regulation of HGK/MAP4K4 in T cells of type 2 diabetes patients

New pathogen-specific immunoPET/MR tracer for molecular imaging of a systemic bacterial infection

Aldehyde dehydrogenase 1A1 in stem cells and cancer

The role of small adaptor proteins in the control of oncogenic signaling driven by tyrosine kinases in human cancer

Oxidation of heat shock protein 60 and protein disulfide isomerase activates ERK and migration of human hepatocellular carcinoma HepG2

Tumor-infiltrating macrophages express interleukin-25 and predict a favorable prognosis in patients with gastric cancer after radical resection

Loss of oncogenic miR-155 in tumor cells promotes tumor growth by enhancing C/EBP-β-mediated MDSC infiltration

Overexpression of lipocalin 2 in human cervical cancer enhances tumor invasion

Aberrant epigenetic regulation in clear cell sarcoma of the kidney featuring distinct DNA hypermethylation and EZH2 overexpression

Bevacizumab specifically decreases elevated levels of circulating KIT+CD11b+ cells and IL-10 in metastatic breast cancer patients

A systematic review of serum autoantibodies as biomarkers for pancreatic cancer detection

Distinct lymphocyte antigens 6 (Ly6) family members Ly6D, Ly6E, Ly6K and Ly6H drive tumorigenesis and clinical outcome

EZH2 promotes cell migration and invasion but not alters cell proliferation by suppressing E-cadherin, partly through association with MALAT-1 in pancreatic cancer

Smad4-dependent suppressor pituitary homeobox 2 promotes PPP2R2A-mediated inhibition of Akt pathway in pancreatic cancer

Brother of the regulator of the imprinted site (BORIS) variant subfamily 6 is involved in cervical cancer stemness and can be a target of immunotherapy

HIF2α contributes to antiestrogen resistance via positive bilateral crosstalk with EGFR in breast cancer cells

Mucin glycosylating enzyme GALNT2 suppresses malignancy in gastric adenocarcinoma by reducing MET phosphorylation

Identification of quinazoline compounds as novel potent inhibitors of Wnt/β-catenin signaling in colorectal cancer cells

Long non-coding RNA FEZF1-AS1 facilitates cell proliferation and migration in colorectal carcinoma

SIRT1 increases YAP- and MKK3-dependent p38 phosphorylation in mouse liver and human hepatocellular carcinoma

Heparanase promotes myeloma progression by inducing mesenchymal features and motility of myeloma cells

Dosing de novo combinations of two targeted drugs: Towards a customized precision medicine approach to advanced cancers

EIF2S3Y suppresses the pluripotency state and promotes the proliferation of mouse embryonic stem cells

Histone acetyltransferase inhibitor CPTH6 preferentially targets lung cancer stem-like cells

Mutual amplification of HNF4α and IL-1R1 composes an inflammatory circuit in Helicobacter pylori associated gastric carcinogenesis

Human telomerase reverse transcriptase (hTERT) promotes gastric cancer invasion through cooperating with c-Myc to upregulate heparanase expression

Efficacy of continued cetuximab for unresectable metastatic colorectal cancer after disease progression during first-line cetuximab-based chemotherapy: a retrospective cohort study

Pinin interacts with C-terminal binding proteins for RNA alternative splicing and epithelial cell identity of human ovarian cancer cells

Oncogenic potential of histone-variant H2A.Z.1 and its regulatory role in cell cycle and epithelial-mesenchymal transition in liver cancer

Polycomb repressor complex 1 promotes gene silencing through H2AK119 mono-ubiquitination in acinar-to-ductal metaplasia and pancreatic cancer cells

Examining plasma microRNA markers for colorectal cancer at different stages

Frequency of CD4+CD25+Foxp3+ cells in peripheral blood in relation to urinary bladder cancer malignancy indicators before and after surgical removal

Reduced RKIP enhances nasopharyngeal carcinoma radioresistance by increasing ERK and AKT activity

Brachyury identifies a class of enteroendocrine cells in normal human intestinal crypts and colorectal cancer

Non-coding RNA LINC00857 is predictive of poor patient survival and promotes tumor progression via cell cycle regulation in lung cancer

Defining specificity and on-target activity of BH3-mimetics using engineered B-ALL cell lines

Role of MIF/CD74 signaling pathway in the development of pleural mesothelioma

Integrative radiogenomic analysis for multicentric radiophenotype in glioblastoma

Identification of novel pathways linking epithelial-to-mesenchymal transition with resistance to HER2-targeted therapy

Regulation of laryngeal squamous cell cancer progression by the lncRNA H19/miR-148a-3p/DNMT1 axis

HIF-3α1 promotes colorectal tumor cell growth by activation of JAK-STAT3 signaling

A strategy to eradicate well-developed Krebs-2 ascites in mice

MicroRNA-150 suppresses cell proliferation and metastasis in hepatocellular carcinoma by inhibiting the GAB1-ERK axis

Downregulation of TFAM inhibits the tumorigenesis of non-small cell lung cancer by activating ROS-mediated JNK/p38MAPK signaling and reducing cellular bioenergetics

Dioxonaphthoimidazoliums AB1 and YM155 disrupt phosphorylation of p50 in the NF-κB pathway

miR-144-3p, a tumor suppressive microRNA targeting ETS-1 in laryngeal squamous cell carcinoma

Hypoxia induces TFE3 expression in head and neck squamous cell carcinoma

Substrate-specific effects of pirinixic acid derivatives on ABCB1-mediated drug transport

CCL-34, a synthetic toll-like receptor 4 activator, modulates differentiation and maturation of myeloid dendritic cells

Antidepressants in association with reducing risk of oral cancer occurrence: a nationwide population-based cohort and nested case-control studies

Long non-coding RNA LINC01133 represses KLF2, P21 and E-cadherin transcription through binding with EZH2, LSD1 in non small cell lung cancer

Overcoming chemo/radio-resistance of pancreatic cancer by inhibiting STAT3 signaling

XPG rs2296147 T>C polymorphism predicted clinical outcome in colorectal cancer

Long non-coding RNA MALAT1 increases AKAP-9 expression by promoting SRPK1-catalyzed SRSF1 phosphorylation in colorectal cancer cells