Novel and potent anti-tumor and anti-metastatic di-2-pyridylketone thiosemicarbazones demonstrate marked differences in pharmacology between the first and second generation lead agents

Genomic landscape of liposarcoma

Metastasis-associated MCL1 and P16 copy number alterations dictate resistance to vemurafenib in a BRAF^V600E patient-derived papillary thyroid carcinoma preclinical model

Longer genotypically-estimated leukocyte telomere length is associated with increased adult glioma risk

Caspase cleavage of iASPP potentiates its ability to inhibit p53 and NF-κB

Genome-wide haplotype association study identify TNFRSF1A, CASP7, LRP1B, CDH1 and TG genes associated with Alzheimer’s disease in Caribbean Hispanic individuals

Antihypertensive treatments in adult autosomal dominant polycystic kidney disease: network meta-analysis of the randomized controlled trials

Oleoylethanolamide, an endogenous PPAR-α ligand, attenuates liver fibrosis targeting hepatic stellate cells

Plasma microRNA expression profiles in Chinese patients with rheumatoid arthritis

NK cell expression of natural cytotoxicity receptors may determine relapse risk in older AML patients undergoing immunotherapy for remission maintenance

The double face of Morgana in tumorigenesis

Non-coding RNAs in cardiac regeneration

Acyl-CoA synthetase-4, a new regulator of mTOR and a potential therapeutic target for enhanced estrogen receptor function in receptor-positive and -negative breast cancer

EMT-induced metabolite signature identifies poor clinical outcome

Genetic variant of PRKAA1 and gastric cancer risk in an eastern Chinese population

The Akt1/IL-6/STAT3 pathway regulates growth of lung tumor initiating cells

ILs-3, 6 and 11 increase, but ILs-10 and 24 decrease stemness of human prostate cancer cells in vitro

Grifolin directly targets ERK1/2 to epigenetically suppress cancer cell metastasis

NF-κB drives acquired resistance to a novel mutant-selective EGFR inhibitor

Identification of a novel platelet antagonist that binds to CLEC-2 and suppresses podoplanin-induced platelet aggregation and cancer metastasis

Colon cancer cell invasion is promoted by protein kinase CK2 through increase of endothelin-converting enzyme-1c protein stability

MiR-542-5p is a negative prognostic factor and promotes osteosarcoma tumorigenesis by targeting HUWE1

Predictive significance of DNA damage and repair biomarkers in triple-negative breast cancer patients treated with neoadjuvant chemotherapy: An exploratory analysis

A functional variant in miR-155 regulation region contributes to lung cancer risk and survival

Genetic and epigenetic characterization of hypodiploid acute lymphoblastic leukemia

Iron deficient erythropoiesis might play key role in development of anemia in cancer patients

LINC00152 promotes proliferation in hepatocellular carcinoma by targeting EpCAM via the mTOR signaling pathway

Bone marrow-derived mesenchymal stem cell-secreted IL-8 promotes the angiogenesis and growth of colorectal cancer

HOXB9 induction of mesenchymal-to-epithelial transition in gastric carcinoma is negatively regulated by its hexapeptide motif

HRD1 suppresses the growth and metastasis of breast cancer cells by promoting IGF-1R degradation

HER3 over-expression and overall survival in gastrointestinal cancers

Enhancement of NAD⁺-dependent SIRT1 deacetylase activity by methylselenocysteine resets the circadian clock in carcinogen-treated mammary epithelial cells

Involvement of MBD4 inactivation in mismatch repair-deficient tumorigenesis

Growth-stimulatory activity of TIMP-2 is mediated through c-Src activation followed by activation of FAK, PI3-kinase/AKT, and ERK1/2 independent of MMP inhibition in lung adenocarcinoma cells

Therapeutics targeting CD90-integrin-AMPK-CD133 signal axis in liver cancer

Phenotypic profile of expanded NK cells in chronic lymphoproliferative disorders: a surrogate marker for NK-cell clonality

Hepatitis B virus (HBV) receptors: Deficiency in tumor results in scant HBV infection and overexpression in peritumor leads to higher recurrence risk

Chemopreventive effect of resveratrol and apocynin on pancreatic carcinogenesis via modulation of nuclear phosphorylated GSK3β and ERK1/2

Cancer metastasis and EGFR signaling is suppressed by amiodarone-induced versican V2

Statin use and breast cancer survival and risk: a systematic review and meta-analysis

TGF-β blockade depletes T regulatory cells from metastatic pancreatic tumors in a vaccine dependent manner

Inhibition of the Tcf/beta-catenin complex increases apoptosis and impairs adrenocortical tumor cell proliferation and adrenal steroidogenesis

miR-150 inhibits terminal erythroid proliferation and differentiation

Stromal cell-mediated mitochondrial redox adaptation regulates drug resistance in childhood acute lymphoblastic leukemia

Mitochondrial oncobioenergetic index: A potential biomarker to predict progression from indolent to aggressive prostate cancer

Infiltrating neutrophils increase bladder cancer cell invasion via modulation of androgen receptor (AR)/MMP13 signals

Dietary fat and fatty acid intake and epithelial ovarian cancer risk: evidence from epidemiological studies

Clinical analysis of intraoperative radiotherapy during breast-conserving surgery of early breast cancer in the Chinese Han population

Phase 1b study of lenvatinib (E7080) in combination with temozolomide for treatment of advanced melanoma

Chemotherapy of metastatic triple negative breast cancer: Experience of using platinum-based chemotherapy