Long non-coding RNAs in normal and malignant hematopoiesis

Lucia Nobili; Marta Lionetti; Antonino Neri

doi:10.18632/oncotarget.9308

Oncotarget

Oncotarget (a primarily oncology-focused, peer-reviewed, open access journal) aims to maximize research impact through insightful peer-review; eliminate borders between specialties by linking different fields of oncology, cancer research and biomedical sciences; and foster application of basic and clinical science.

Its scope is unique. The term "oncotarget" encompasses all molecules, pathways, cellular functions, cell types, and even tissues that can be viewed as targets relevant to cancer as well as other diseases. The term was introduced in the inaugural Editorial, Introducing Oncotarget.

As of January 1, 2022, Oncotarget has shifted to a continuous publishing model. Papers will now be published continuously within yearly volumes in their final and complete form and then quickly released to Pubmed.

Subscribe to receive alerts once a paper has been published by Oncotarget.

Impact Journals, LLC is the publisher of Oncotarget: www.impactjournals.com.

Impact Journals is a member of the Wellcome Trust List of Compliant Publishers.

Impact Journals is a member of the Society for Scholarly Publishing.

On December 23, 2022, Oncotarget server experienced a DDoS attack. As a result, Oncotarget site was inaccessible for a few hours. Oncotarget team swiftly dealt with the situation and took it under control. This malicious action will be reported to the FBI.

Reviews:

Long non-coding RNAs in normal and malignant hematopoiesis

Lucia Nobili, Marta Lionetti and Antonino Neri _

PDF | HTML | How to cite

Oncotarget. 2016; 7:50666-50681. https://doi.org/10.18632/oncotarget.9308

Metrics: PDF 3121 views | HTML 3623 views | ?

Abstract

Lucia Nobili1, Marta Lionetti1 and Antonino Neri1

1 Department of Oncology and Hemato-Oncology, Università degli Studi di Milano, Hematology, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milano, Italy

Correspondence to:

Antonino Neri, email:

Keywords: long non-coding RNAs; hematopoiesis; hematological malignancies; transcriptional regulation; translation regulation

Received: March 09, 2016 Accepted: May 01, 2016 Published: May 11, 2016

Abstract

Long non-coding RNAs (lncRNAs) are defined as ncRNAs of more than 200 nt in length. They are involved in a large spectrum of biological processes, such as maintenance of genome integrity, genomic imprinting, cell differentiation, and development by means of mechanisms that remain to be fully elucidated. Besides their role in normal cellular physiology, accumulating evidence has linked lncRNA expression and functions to cancer development and progression. In this review, we summarize and discuss what is known about their expression and roles in hematopoiesis with a particular focus on their cell-type speciﬁcity, functional interactions, and involvement in the pathobiology of hematological malignancies.

All site content, except where otherwise noted, is licensed under a Creative Commons Attribution 4.0 License.
PII: 9308

Publication Alerts

Reviews:

Long non-coding RNAs in normal and malignant hematopoiesis

Abstract