Oncotarget

Research Papers:

Atypical appearance of hepatic hemangiomas with contrast-enhanced ultrasound

Min Huang, Qiyu Zhao, Fen Chen, Qihan You, Tian’an Jiang _

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Oncotarget. 2018; 9:12662-12670. https://doi.org/10.18632/oncotarget.24185

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Abstract

Min Huang1, Qiyu Zhao1, Fen Chen2, Qihan You3 and Tian’an Jiang1

1Department of Ultrasound, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, China

2Department of Hepatobiliary Pancreatic Surgery, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, China

3Department of Pathology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, China

Correspondence to:

Tian’an Jiang, email: chenmy@zju.edu.cn

Keywords: hepatic hemangioma; contrast-enhanced ultrasound; atypical

Received: September 01, 2017     Accepted: January 04, 2018     Published: January 11, 2018

ABSTRACT

To describe the atypical enhancement pattern of hepatic hemangiomas on contrast-enhanced sonography. 22 patients with hepatic hemangiomas that were atypical on contrast-enhanced ultrasound were included in the study, all of them were confirmd by biopsy or surgery pathology. Atypical appearance of hepatic hemangiomas on contrast-enhanced ultrasound were divided into seven subtypes: (i) peripheral nodular enhancement in the arterial phase with centripedal filling, hypoechoic change in the delayed phase; (ii) peripheral circular enhancement; (iii) peripheral nodular enhancement; (iv) none enhancement; (v) septal enhancement; (vi) a central enhancing focus in the arterial phase, followed by a centrifugal enhancement in the portal venous phase, hypoechoic change in the delayed phase; (vii) slowly spoke wheel enhancement. Atypical appearance of hepatic hemangiomas were various. Radiologists should be aware. Establishing knowledge of the entire spectrum of atypical hepatic hemangiomas may benefit the rational approach to future cases.


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