Clinical Research Papers:
Impact of socioeconomic status on survival of colorectal cancer patients
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Qian Zhang1,2, Yufu Wang1,2, Hanqing Hu1,2, Rui Huang1,2, Lei Xie1,2, Enrui Liu1,2, Ying-Gang Chen1,2, Guiyu Wang1,2 and Xishan Wang1,2,3
1Department of Colorectal Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150086, PR China
2Colorectal Cancer Institute of Harbin Medical University, Harbin, Heilongjiang 150086, PR China
3Department of Colorectal Surgery, Cancer Hospital of Chinese Academy Sciences, Beijing, 100021, PR China
Xishan Wang, email: firstname.lastname@example.org
Guiyu Wang, email: email@example.com
Ying-Gang Chen, email: firstname.lastname@example.org
Keywords: socioeconomic, SEER, colorectal cancer, survival, adverse
Received: October 17, 2016 Accepted: May 29, 2017 Published: September 13, 2017
Socioeconomic status (SES) has an impact on the survival of various cancers, but it has not been fully understood in colorectal cancer (CRC).The Surveillance, Epidemiology and End Results database was adopted to detect the role of SES in the survival outcomes of CRC. A total of 184,322 eligible patients were included and SES status was analyzed. The multivariable analysis showed that Non-Hispanic Black (HR, 1.20; 95% CI, 1.15–1.24), being widowed (HR, 1.04; 95% CI, 1.01–1.07), any Medicaid (HR, 1.36; 95% CI, 1.33–1.39) and the lowest education level group patients had relative poorer prognosis. Besides, sex, tumor location, age, differentiation level and American Joint Committee on Cancer stage also had significant effects on overall survival of CRC. The individuals were further divided into five groups according to the number of survival-adverse factors. All of the four groups containing adverse factors showed impaired survival outcomes compared with the group containing no adverse factor.
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