Relevance between GerdQ score and the severity of reflux esophagitis in Uygur and Han Chinese

Man Wang; Jing-Zhan Zhang; Xiao-Jing Kang; Li Li; Xiao-Ling Huang; Kuerbanjiang Aihemaijiang; Aheman Ayinuer; Yue-Xian Li; Xiao-Lei He; Feng Gao

doi:10.18632/oncotarget.20146

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Research Papers:

Relevance between GerdQ score and the severity of reflux esophagitis in Uygur and Han Chinese

Man Wang, Jing-Zhan Zhang, Xiao-Jing Kang, Li Li, Xiao-Ling Huang, Kuerbanjiang Aihemaijiang, Aheman Ayinuer, Yue-Xian Li, Xiao-Lei He and Feng Gao _

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Oncotarget. 2017; 8:74371-74377. https://doi.org/10.18632/oncotarget.20146

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Abstract

Man Wang1,*, Jing-Zhan Zhang2,*, Xiao-Jing Kang2, Li Li1, Xiao-Ling Huang1, Kuerbanjiang Aihemaijiang1, Aheman Ayinuer1, Yue-Xian Li1, Xiao-Lei He1 and Feng Gao1

1Department of Gastroenterology, People’s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, China

2Department of Dermatology, People’s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, China

*These authors have contributed equally to this work

Correspondence to:

Feng Gao, email: [email protected]

Keywords: reflux esophagitis, gastroesophageal reflux disease questionnaire, endoscopy

Received: December 27, 2016 Accepted: May 29, 2017 Published: August 10, 2017

ABSTRACT

Gastroesophageal reflux disease questionnaire (GerdQ) was used to investigate the inpatients with typical reflux related symptoms in Gastroenterology. According to heartburn, regurgitation, abdominal pain, nausea, sleep disorders, whether taking over the counter (OTC) drugs 6 points to score. Using endoscopy as the gold standard for the diagnosis of reflux esophagitis (RE), and the results were compared with GerdQ score to determine the threshold value for RE, to analyze the distribution of GerdQ score for patients with RE, to assess the relationship between the GerdQ score and the severity of RE. A total of 1233 patients were enrolled in this study, including 538 patients had RE and 695 had not. There was statistical significance in the GerdQ score of RE group and non-RE group (P <0.05), showing that significant correlation between the score and the occurrence of RE. GerdQ score and the severity of RE were positively correlated. Further research also showed that there was a direct correlation between GerdQ score and the severity of RE in the Uygur and Han. GerdQ seems to be an useful screening tool in initial diagnosis of RE, and positively correlated with the severity of RE.

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Research Papers:

Relevance between GerdQ score and the severity of reflux esophagitis in Uygur and Han Chinese

Abstract