Research Papers:
Dosimetric evaluation of the skin-sparing effects of 3-dimensional conformal radiotherapy and intensity-modulated radiotherapy for left breast cancer
Metrics: PDF 1687 views | HTML 2503 views | ?
Abstract
In Young Jo1, Shin-Wook Kim2, Seok Hyun Son2
1Department of Radiation Oncology, Samsung Medical Center, Seoul, Korea
2Department of Radiation Oncology, Incheon St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea
Correspondence to:
Seok Hyun Son, email: [email protected]
Keywords: breast cancer, 3-dimensioanl conformal radiotherapy, intensity-modulated radiotherapy, radiation-related dermatitis, skin-sparing
Received: August 19, 2016 Accepted: December 01, 2016 Published: December 09, 2016
ABSTRACT
The purpose of this study was to evaluate the skin-sparing effects of 3-dimensional conformal radiotherapy (3D-CRT) and intensity-modulated radiotherapy (IMRT) in patients with early left-sided breast cancer. Twenty left breast cancer patients treated with whole breast radiotherapy following breast-conserving surgery were enrolled in this study, and the 3D-CRT and IMRT plans were generated for each patient. To evaluate the dose delivered to the skin, 2 mm thickness skin (2-mm skin) and 3 mm thickness skin (3-mm skin) were contoured and a dosimetric comparison between the 2 plans was performed. The target volume coverage was better in IMRT than in 3D-CRT. The mean dose was 50.8 Gy for 3D-CRT and 51.1 Gy for IMRT. V40Gy was 99.4% for 3D-CRT and 99.9% for IMRT. In the case of skin, the mean dose was higher in 3D-CRT than in IMRT (mean dose of 2-mm skin: 32.8 Gy and 24.2 Gy; mean dose of 3-mm skin: 37.2 Gy and 27.8 Gy, for 3D-CRT and IMRT, respectively). These results indicated that the skin-sparing effect is more prominent in IMRT compared to 3D-CRT without compromising the target volume coverage.
All site content, except where otherwise noted, is licensed under a Creative Commons Attribution 4.0 License.
PII: 13830