Efficacy of splint therapy for the management of temporomandibular disorders: a meta-analysis
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Chao Zhang1,*, Jun-Yi Wu1,2,*, Dong-Lai Deng3, Bing-Yang He3, Yuan Tao1, Yu-Ming Niu1,4 and Mo-Hong Deng5
1 Center for Evidence-Based Medicine and Clinical Research, Taihe Hospital, Hubei University of Medicine, South Renmin Road, Shiyan, China
2 School of Stomatology, Hubei University of Medicine, Shiyan, China
3 The State Key Laboratory Breeding Base of Basic Science of Stomatology & Key Laboratory of Oral Biomedicine, Ministry of Education, School & Hospital of Stomatology, Wuhan University, Wuhan, China
4 Department of Stomatology, Taihe Hospital, Hubei University of Medicine, Shiyan, China
5 The State Key Laboratory Breeding Base of Basic Science of Stomatology & Key Laboratory of Oral Biomedicine, Ministry of Education, Department of Oral and Maxillofacial Surgery, School & Hospital of Stomatology, Wuhan University, Wuhan, China
* These authors have contributed equally to this work
Yu-Ming Niu, email:
Mo-Hong Deng, email:
Keywords: temporomandibular disorders; splint; maximal mouth opening; visual analogue scales of pain; meta-analysis
Received: August 24, 2016 Accepted: October 24, 2016 Published: November 03, 2016
Temporomandibular disorders (TMD) are a group of clinical problems affecting temporomandibular joint (TMJ), myofascial muscles and other related structures. Splint therapy is the most commonly used approach to treatment of TMD, but its effectiveness is remains unclear. We therefore conducted a meta-analysis to evaluate the effectiveness of splint therapy for TMD in adults. The electronic databases PubMed, EMBASE, Cochrane Library, and ClinicalTrials.gov were searched for reports published up to March 31, 2016. Thirteen eligible studies involving 538 patients were identified. The results indicated that splint therapy increased maximal mouth opening (MMO) for patients with a MMO <45mm and reduced pain intensity measured using the visual analogue scale (VAS) for patients with TMD without specific description (TMDSD). Splint therapy also reduced the frequency of painful episodes for patients with TMJ clicking. No publication bias was observed, as determined with Egger’s test for all outcomes. On the basis of this evidence, we recommend the use of splints for the treatment and control of TMD in adults.
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