Long noncoding RNAs in head and neck cancer

Xiuhua Li; Yongbing Cao; Xiaojian Gong; Hongjiao Li

doi:10.18632/oncotarget.12960

Oncotarget

Oncotarget (a primarily oncology-focused, peer-reviewed, open access journal) aims to maximize research impact through insightful peer-review; eliminate borders between specialties by linking different fields of oncology, cancer research and biomedical sciences; and foster application of basic and clinical science.

Its scope is unique. The term "oncotarget" encompasses all molecules, pathways, cellular functions, cell types, and even tissues that can be viewed as targets relevant to cancer as well as other diseases. The term was introduced in the inaugural Editorial, Introducing Oncotarget.

As of January 1, 2022, Oncotarget has shifted to a continuous publishing model. Papers will now be published continuously within yearly volumes in their final and complete form and then quickly released to Pubmed.

Subscribe to receive alerts once a paper has been published by Oncotarget.

Impact Journals, LLC is the publisher of Oncotarget: www.impactjournals.com.

Impact Journals is a member of the Wellcome Trust List of Compliant Publishers.

Impact Journals is a member of the Society for Scholarly Publishing.

On December 23, 2022, Oncotarget server experienced a DDoS attack. As a result, Oncotarget site was inaccessible for a few hours. Oncotarget team swiftly dealt with the situation and took it under control. This malicious action will be reported to the FBI.

Reviews:

Long noncoding RNAs in head and neck cancer

Xiuhua Li, Yongbing Cao, Xiaojian Gong and Hongjiao Li _

PDF | HTML | How to cite

Oncotarget. 2017; 8:10726-10740. https://doi.org/10.18632/oncotarget.12960

Metrics: PDF 3795 views | HTML 3667 views | ?

Abstract

Xiuhua Li1,2, Yongbing Cao1, Xiaojian Gong1 and Hongjiao Li2

1 School of Pharmacology, China Pharmaceutical University, Nanjing, Jiangsu, P. R. China

2 Department of Stomatology,ChanghaiHospital, Second Military Medical University, Shanghai, P. R. China

Correspondence to:

Hongjiao Li, email:

Xiaojian Gong, email:

Keywords: HNC; lncRNAs; function; mechanism; clinical application

Received: October 05, 2016 Accepted: October 19, 2016 Published: October 27, 2016

Abstract

Head and neck cancers (HNCs) include a series of malignant tumors arising in epithelial tissues, typically oral cancer, laryngeal cancer, nasopharynx cancer and thyroid cancer. HNCs are important contributors to cancer incidence and mortality, leading to approximately 225,100 new patients and 77,500 deaths in China every year. Determination of the mechanisms of HNC carcinogenesis and progression is an urgent priority in HNC treatment. Long noncoding RNAs (lncRNAs) are noncoding RNAs longer than 200 bps. lncRNAs have been reported to participate in a broad scope of biological processes, and lncRNA dysregulation leads to diverse human diseases, including cancer. In this review, we focus on lncRNAs that are dysregulated in HNCs, summarize the latest findings regarding the function and molecular mechanisms of lncRNAs in HNC carcinogenesis and progression, and discuss the clinical application of lncRNAs in HNC diagnosis, prognosis and therapy.

All site content, except where otherwise noted, is licensed under a Creative Commons Attribution 4.0 License.
PII: 12960

Publication Alerts

Reviews:

Long noncoding RNAs in head and neck cancer

Abstract