Activity modifies adult brain maturity

A genetic polymorphism repurposes the G-protein coupled and membrane-associated estrogen receptor GPER to a transcription factor-like molecule promoting paracrine signaling between stroma and breast carcinoma cells

Induction of anti-aging gene klotho with a small chemical compound that demethylates CpG islands

A hydrophobic residue in the TALE homeodomain of PBX1 promotes epithelial-to-mesenchymal transition of gastric carcinoma

Distinct plasma lipids profiles of recurrent ovarian cancer by liquid chromatography-mass spectrometry

Effects of renal denervation on monocrotaline induced pulmonary remodeling

Silencing PRDM14 expression by an innovative RNAi therapy inhibits stemness, tumorigenicity, and metastasis of breast cancer

CD54⁺ rabbit adipose-derived stem cells overexpressing HIF-1α facilitate vascularized fat flap regeneration

Characterization of fusion genes in common and rare epithelial ovarian cancer histologic subtypes

Evaluation of radiofluorinated carboximidamides as potential IDO-targeted PET tracers for cancer imaging

The anti-neoplastic activity of Vandetanib against high-risk medulloblastoma variants is profoundly enhanced by additional PI3K inhibition

Association between body mass index and endometriosis risk: a meta-analysis

Unidimensional measurement may be superior to assess primary tumor response after neoadjuvant chemotherapy for nasopharyngeal carcinoma

The prognostic value of negative lymph node count for patients with gastric cancer who received preoperative radiotherapy

Nucleocytoplasmic shuttling of SOX14A and SOX14B transcription factors

Association of two microRNA polymorphisms miR-27 rs895819 and miR-423 rs6505162 with the risk of cancer

Oral cancer cells sustainedly infected with Porphyromonas gingivalis exhibit resistance to Taxol and have higher metastatic potential

MALAT1 predicts poor survival in osteosarcoma patients and promotes cell metastasis through associating with EZH2

A comparison of pectoralis versus lumbar skeletal muscle indices for defining sarcopenia in diffuse large B-cell lymphoma - two are better than one

Overexpression of the transcription factor ATF3 with a regulatory molecular signature associates with the pathogenic development of colorectal cancer

Incidence and survival differences in esophageal cancer among ethnic groups in the United States

TROP2 promotes proliferation, migration and metastasis of gallbladder cancer cells by regulating PI3K/AKT pathway and inducing EMT

Multiple-gene panel analysis in a case series of 255 women with hereditary breast and ovarian cancer

Increased expression of deleted in malignant brain tumors (DMBT1) gene in precancerous gastric lesions: Findings from human and animal studies

Elevated CRP levels predict poor outcome and tumor recurrence in patients with thymic epithelial tumors: A pro- and retrospective analysis

BCL2L10 positive cells in bone marrow are an independent prognostic factor of azacitidine outcome in myelodysplastic syndrome and acute myeloid leukemia

Influence of serum cholesterol level and statin treatment on prostate cancer aggressiveness

HOXB7 promotes tumor progression via bFGF-induced activation of MAPK/ERK pathway and indicated poor prognosis in hepatocellular carcinoma

Liposomal co-delivered oleanolic acid attenuates doxorubicin-induced multi-organ toxicity in hepatocellular carcinoma

Baseline clinical predictors of antitumor response to the PARP inhibitor olaparib in germline BRCA1/2 mutated patients with advanced ovarian cancer

Mathematical modeling for Phase I cancer trials: A study of metronomic vinorelbine for advanced non-small cell lung cancer (NSCLC) and mesothelioma patients

Association between genetic variants and esophageal cancer risk

Aquaporins 1, 3 and 8 expression in irritable bowel syndrome rats’ colon via NF-κB pathway

IRF5 is elevated in childhood-onset SLE and regulated by histone acetyltransferase and histone deacetylase inhibitors

PDZ binding kinase, regulated by FoxM1, enhances malignant phenotype via activation of β-Catenin signaling in hepatocellular carcinoma

The cell of origin dictates the temporal course of neurofibromatosis-1 (Nf1) low-grade glioma formation

Sulfatase-1 overexpression indicates poor prognosis in urothelial carcinoma of the urinary bladder and upper tract

Histogram analysis of diffusion kurtosis imaging of nasopharyngeal carcinoma: Correlation between quantitative parameters and clinical stage

Secretome analysis of breast cancer-associated adipose tissue to identify paracrine regulators of breast cancer growth

The synthetic antihyperlipidemic drug potassium piperate selectively kills breast cancer cells through inhibiting G1-S-phase transition and inducing apoptosis

Insulin-like growth factor 2 axis supports the serum-independent growth of malignant rhabdoid tumor and is activated by microenvironment stress

Isradipine attenuates MPTP-induced dopamine neuron degeneration by inhibiting up-regulation of L-type calcium channels and iron accumulation in the substantia nigra of mice

Inhibition of nuclear factor-κB signal by pyrrolidine dithiocarbamate alleviates lipopolysaccharide-induced acute lung injury

Activation of signal transducer and activator of transcription 3 (STAT3) signaling in EGFR mutant non-small-cell lung cancer (NSCLC)

MicroRNA-155 attenuates late sepsis-induced cardiac dysfunction through JNK and β-arrestin 2

A cancer vaccine based on fluorine-modified sialyl-Tn induces robust immune responses in a murine model

High throughput sequencing identifies an imprinted gene, Grb10, associated with the pluripotency state in nuclear transfer embryonic stem cells

Identifying CpG sites with different differential methylation frequencies in colorectal cancer tissues based on individualized differential methylation analysis

ADAM9 enhances CDCP1 by inhibiting miR-1 through EGFR signaling activation in lung cancer metastasis

Dietary factors and microRNA-binding site polymorphisms in the IL13 gene: risk and prognosis analysis of colorectal cancer

High expression of miR-493-5p positively correlates with clinical prognosis of non small cell lung cancer by targeting oncogene ITGB1

Immune signature of metastatic breast cancer: Identifying predictive markers of immunotherapy response

Effects and related mechanisms of serotonin on malignant biological behavior of hepatocellular carcinoma via regulation of Yap

Alpha-mangostin induces apoptosis through activation of reactive oxygen species and ASK1/p38 signaling pathway in cervical cancer cells

Intratumoral depletion of regulatory T cells using CD25-targeted photodynamic therapy in a mouse melanoma model induces antitumoral immune responses

Interaction of glycosphingolipids GD3 and GD2 with growth factor receptors maintains breast cancer stem cell phenotype

5T4 oncofoetal glycoprotein: an old target for a novel prostate cancer immunotherapy

MEK inhibitors cobimetinib and trametinib, regressed a gemcitabine-resistant pancreatic-cancer patient-derived orthotopic xenograft (PDOX)

Resveratrol may reverse the effects of long-term occupational exposure to electromagnetic fields on workers of a power plant

Wisteria floribunda agglutinin-positive human Mac-2 binding protein predicts liver cancer development in chronic hepatitis B patients under antiviral treatment

Inflammatory cytokines are associated with response and prognosis in patients with esophageal cancer

Effects of microRNA-19b on airway remodeling, airway inflammation and degree of oxidative stress by targeting TSLP through the Stat3 signaling pathway in a mouse model of asthma

Massively parallel sequencing and genome-wide copy number analysis revealed a clonal relationship in benign metastasizing leiomyoma

Comparison of treatment outcome between living donor liver transplantation and sorafenib for patients with hepatocellular carcinoma beyond the Milan criteria

LncRNA TINCR attenuates cardiac hypertrophy by epigenetically silencing CaMKII

KIR2DL5 mutation and loss underlies sporadic dermal neurofibroma pathogenesis and growth

HDAC4 stimulates MRTF-A expression and drives fibrogenesis in hepatic stellate cells by targeting miR-206

FOXM1 predicts overall and disease specific survival in muscle-invasive urothelial carcinoma and presents a differential expression between bladder cancer subtypes

Nac1 promotes self-renewal of embryonic stem cells through direct transcriptional regulation of c-Myc

Peiminine inhibits colorectal cancer cell proliferation by inducing apoptosis and autophagy and modulating key metabolic pathways

Immune consequences of penfluridol treatment associated with inhibition of glioblastoma tumor growth

αMSH inhibits adipose inflammation via reducing FoxOs transcription and blocking Akt/JNK pathway in mice

Microwave ablation combined with attenuated Salmonella typhimurium for treating hepatocellular carcinoma in a rat model

Gallic acid inhibits the release of ADAMTS4 in nucleus pulposus cells by inhibiting p65 phosphorylation and acetylation of the NF-κB signaling pathway

Osteoclast proton pump regulator Atp6v1c1 enhances breast cancer growth by activating the mTORC1 pathway and bone metastasis by increasing V-ATPase activity

Enolase 1 stimulates glycolysis to promote chemoresistance in gastric cancer

N-myc downstream-regulated gene 1 promotes oxaliplatin-triggered apoptosis in colorectal cancer cells via enhancing the ubiquitination of Bcl-2

Biological characterization of SN32976, a selective inhibitor of PI3K and mTOR with preferential activity to PI3Kα, in comparison to established pan PI3K inhibitors

Severe hypertriglyceridemia due to two novel loss-of-function lipoprotein lipase gene mutations (C310R/E396V) in a Chinese family associated with recurrent acute pancreatitis

Dalbinol, a rotenoid from Amorpha fruticosa L., exerts anti-proliferative activity by facilitating β-catenin degradation in hepatocellular carcinoma cells

Involvement of p38-βTrCP-Tristetraprolin-TNFα axis in radiation pneumonitis

Circulating pre-treatment Epstein-Barr virus DNA as prognostic factor in locally-advanced nasopharyngeal cancer in a non-endemic area

Prognostic implication of leucocyte subpopulations in diffuse large B-cell lymphoma

HIF-2α promotes the formation of vasculogenic mimicry in pancreatic cancer by regulating the binding of Twist1 to the VE-cadherin promoter

Optimizing a machine learning based glioma grading system using multi-parametric MRI histogram and texture features

Neoadjuvant radiation followed by resection versus upfront resection for locally advanced pancreatic cancer patients: a propensity score matched analysis

Modified protocol for enhanced recovery after surgery is beneficial for Chinese cancer patients undergoing pancreaticoduodenectomy

Morin promotes prostate cancer cells chemosensitivity to paclitaxel through miR-155/GATA3 axis

An ultra-sensitive biophysical risk assessment of light effect on skin cells

Long non-coding RNAs could act as vectors for paternal heredity of high fat diet-induced obesity

Cullin 3^SPOP ubiquitin E3 ligase promotes the poly-ubiquitination and degradation of HDAC6

mTOR signaling mediates resistance to tankyrase inhibitors in Wnt-driven colorectal cancer

Estrogen-activated MDM2 disrupts mammary tissue architecture through a p53-independent pathway

TRIB1 promotes colorectal cancer cell migration and invasion through activation MMP-2 via FAK/Src and ERK pathways

High expression of GPR116 indicates poor survival outcome and promotes tumor progression in colorectal carcinoma

Long non-coding RNA UCA1 promotes gallbladder cancer progression by epigenetically repressing p21 and E-cadherin expression

Pediatric and adult glioblastoma radiosensitization induced by PI3K/mTOR inhibition causes early metabolic alterations detected by nuclear magnetic resonance spectroscopy

Co-targeting of IGF1R/mTOR pathway by miR-497 and miR-99a impairs hepatocellular carcinoma development

EphA2 affects the sensitivity of oxaliplatin by inducing EMT in oxaliplatin-resistant gastric cancer cells

Bufalin reverses ABCB1-mediated drug resistance in colorectal cancer

Knockdown of HDAC1 expression suppresses invasion and induces apoptosis in glioma cells

Tissue and serum lipidome shows altered lipid composition with diagnostic potential in mycosis fungoides

Comparison of differentiated thyroid carcinoma recurrence and its clinical features in children of different ages

Lymph node metastasis and the physicochemical micro-environment of pancreatic ductal adenocarcinoma xenografts

Identifying drug-pathway association pairs based on L₁L_2,1-integrative penalized matrix decomposition

Heparin-based coacervate of bFGF facilitates peripheral nerve regeneration by inhibiting endoplasmic reticulum stress following sciatic nerve injury

Rcan2 and estradiol independently regulate body weight in female mice

YB-1 regulates tumor growth by promoting MACC1/c-Met pathway in human lung adenocarcinoma

Assessment of concordance between fresh-frozen and formalin-fixed paraffin embedded tumor DNA methylation using a targeted sequencing approach

Higher platelet distribution width predicts poor prognosis in laryngeal cancer

Circulating microRNAs as potential biomarkers for coronary plaque rupture

Non-invasive detection of somatic mutations using next-generation sequencing in primary central nervous system lymphoma

Polymorphisms and expression pattern of circular RNA circ-ITCH contributes to the carcinogenesis of hepatocellular carcinoma

Physiologically based pharmacokinetic modeling for predicting irinotecan exposure in human body

A novel method to generate Salmonella Typhi Ty21a ghosts exploiting the λ phage holin-endolysin system

Aberrant patterns of local and long-range functional connectivity densities in schizophrenia

c-Fos-dependent miR-22 targets MDC1 and regulates DNA repair in terminally differentiated cells

Cationic liquid crystalline nanoparticles for the delivery of synthetic RNAi-based therapeutics

Preoperative albumin/globulin ratio has predictive value for patients with laryngeal squamous cell carcinoma

Efficacy and safety of different molecular targeted agents based on chemotherapy for gastric cancer patients treatment: a network meta-analysis

Do histological variants in urothelial carcinoma of the bladder portend poor prognosis? A systematic review and meta-analysis

Meta-analysis indicating that high ALCAM expression predicts poor prognosis in colorectal cancer

SATB1 overexpression correlates with gastrointestinal neoplasms invasion and metastasis: a meta-analysis for Chinese population

Adjuvant celecoxib and lanreotide following transarterial chemoembolisation for unresectable hepatocellular carcinoma: a randomized pilot study

Interaction between PPAR γ and SORL1 gene with Late-Onset Alzheimer’s disease in Chinese Han Population

In-depth proteomic profiling of left ventricular tissues in human end-stage dilated cardiomyopathy

Lymph node status as a prognostic factor after palliative resection of primary tumor for patients with metastatic colorectal cancer

Clinical application of the supraorbital key-hole approach to the treatment of unilateral-dominant bilateral frontal contusions

High serum lactate dehydrogenase predicts an unfavorable outcome in Chinese elderly patients with multiple myeloma

A meta-analysis of randomized controlled trials comparing the efficacy and safety of anastrozole versus tamoxifen for breast cancer

Comparison of combined leflunomide and low-dose corticosteroid therapy with full-dose corticosteroid monotherapy for progressive IgA nephropathy

SNM1B/Apollo in the DNA damage response and telomere maintenance

Prognostic significance of SATB1 in gastrointestinal cancer: a meta-analysis and literature review

Long non-coding RNAs in renal cell carcinoma: A systematic review and clinical implications

Redirecting tumor-associated macrophages to become tumoricidal effectors as a novel strategy for cancer therapy

Adducin in tumorigenesis and metastasis

Global scientific trends on exosome research during 2007–2016: a bibliometric analysis

Cell matrix adhesions in cancer: The proteins that form the glue

Association between the ERCC2 Asp312Asn polymorphism and risk of cancer

Implementing liquid biopsies into clinical decision making for cancer immunotherapy

Correction: Hypermethylation of the CHRDL1 promoter induces proliferation and metastasis by activating Akt and Erk in gastric cancer