A nutritional perspective on cellular rejuvenation

Digesting dietary miRNA therapeutics

Δ113p53/Δ133p53: survival and integrity

Plant and animal organelles in cell death

Tumour modelling using viral vectors

Long tails, short telomeres: Dyskeratosis congenita

MicroRNA expression and its implications for diagnosis and therapy of gallbladder cancer

DNA methylation and cognitive aging

miR-181c associates with tumor relapse of high grade osteosarcoma

AKT inhibition overcomes rapamycin resistance by enhancing the repressive function of PRAS40 on mTORC1/4E-BP1 axis

β-catenin activation drives thymoma initiation and progression in mice

P73 tumor suppressor and its targets, p21 and PUMA, are required for madin-darby canine kidney cell morphogenesis by maintaining an appropriate level of epithelial to mesenchymal transition

Doxycycline down-regulates DNA-PK and radiosensitizes tumor initiating cells: Implications for more effective radiation therapy

Soluble IL6R represents a miR-34a target: potential implications for the recently identified IL-6R/STAT3/miR-34a feed-back loop

Maintaining human fetal pancreatic stellate cell function and proliferation require β1 integrin and collagen I matrix interactions

Paroxysmal supraventricular tachycardia as first manifestation of right atrial hemangioma during endovascular treatment of intracranial arteriovenous fistulas

APOε2 and education in cognitively normal older subjects with high levels of AD pathology at autopsy: findings from the Nun Study

Dynamic self-guiding analysis of Alzheimer’s disease

miR-221/222 induces pancreatic cancer progression through the regulation of matrix metalloproteinases

CXCL16/CXCR6 chemokine signaling mediates breast cancer progression by pERK1/2-dependent mechanisms

Infiltrating mast cells enhance prostate cancer invasion via altering LncRNA-HOTAIR/PRC2-androgen receptor (AR)-MMP9 signals and increased stem/progenitor cell population

EFEMP1 promotes the migration and invasion of osteosarcoma via MMP-2 with induction by AEG-1 via NF-κB signaling pathway

The association between PD-L1 and EGFR status and the prognostic value of PD-L1 in advanced non-small cell lung cancer patients treated with EGFR-TKIs

Kras activation in p53-deficient myoblasts results in high-grade sarcoma formation with impaired myogenic differentiation

Lemur Tyrosine Kinase 2, a novel target in prostate cancer therapy

Necrosis targeted radiotherapy with iodine-131-labeled hypericin to improve anticancer efficacy of vascular disrupting treatment in rabbit VX2 tumor models

uPAR-targeted multimodal tracer for pre- and intraoperative imaging in cancer surgery

NKX2-1-mediated p53 expression modulates lung adenocarcinoma progression via modulating IKKβ/NF-κB activation

Deltex-3-like (DTX3L) stimulates metastasis of melanoma through FAK/PI3K/AKT but not MEK/ERK pathway

Fibroblast surface-associated FGF-2 promotes contact-dependent colorectal cancer cell migration and invasion through FGFR-SRC signaling and integrin α_vβ₅-mediated adhesion

Trop-2 is up-regulated in invasive prostate cancer and displaces FAK from focal contacts

JAK2 inhibitor TG101348 overcomes erlotinib-resistance in non-small cell lung carcinoma cells with mutated EGF receptor

Frequent amplification of AIB1, a critical oncogene modulating major signaling pathways, is associated with poor survival in gastric cancer

Highly effective NK cells are associated with good prognosis in patients with metastatic prostate cancer

Ectopic expression of a novel CD22 splice-variant regulates survival and proliferation in malignant T cells from cutaneous T cell lymphoma (CTCL) patients.

PUMA mediates the combinational therapy of 5-FU and NVP-BEZ235 in colon cancer

The EMT-activator ZEB1 induces bone metastasis associated genes including BMP-inhibitors

Anticancer activity of halofuginone in a preclinical model of osteosarcoma: inhibition of tumor growth and lung metastases

Wnt-C59 arrests stemness and suppresses growth of nasopharyngeal carcinoma in mice by inhibiting the Wnt pathway in the tumor microenvironment

MicroRNA-33a-mediated downregulation of Pim-3 kinase expression renders human pancreatic cancer cells sensitivity to gemcitabine

Pit-1 inhibits BRCA1 and sensitizes human breast tumors to cisplatin and vitamin D treatment

Rational combination of MEK inhibitor and the STAT3 pathway modulator for the therapy in K-Ras mutated pancreatic and colon cancer cells

Reactive stroma component COL6A1 is upregulated in castration-resistant prostate cancer and promotes tumor growth

C-Jun recruits the NSL complex to regulate its target gene expression by modulating H4K16 acetylation and promoting the release of the repressive NuRD complex

Combined inhibition of Bcl-2/Bcl-xL and Usp9X/Bag3 overcomes apoptotic resistance in glioblastoma in vitro and in vivo

Destabilisation of dimeric 14-3-3 proteins as a novel approach to anti-cancer therapeutics

Perioperative cerebral ischemia promote infiltrative recurrence in glioblastoma

Absolute quantification of cell-free microRNAs in cancer patients

Tumor promotion by γ and suppression by β non-muscle actin isoforms

Lysine-specific demethylase (LSD1/KDM1A) and MYCN cooperatively repress tumor suppressor genes in neuroblastoma

Proteomic profiling of high risk medulloblastoma reveals functional biology

Endoplasmic reticulum targeting in Ewing’s sarcoma by the alkylphospholipid analog edelfosine

Cytogenomic profiling of breast cancer brain metastases reveals potential for repurposing targeted therapeutics

Comparison of the selective targeting efficacy of Salmonella typhimurium A1-R and VNP20009 on the Lewis lung carcinoma in nude mice

RPPA-based protein profiling reveals eIF4G overexpression and 4E-BP1 serine 65 phosphorylation as molecular events that correspond with a pro-survival phenotype in chronic lymphocytic leukemia

Role of TGF-β signaling in uterine carcinosarcoma

Dynamic treatment effect (DTE) curves reveal the mode of action for standard and experimental cancer therapies

IPP51, a chalcone acting as a microtubule inhibitor with in vivo antitumor activity against bladder carcinoma

Monocytes and macrophages, implications for breast cancer migration and stem cell-like activity and treatment

Assessment of folate receptor-β expression in human neoplastic tissues