Resistance to EGFR inhibitors: Molecular determinants and the enigma of head and neck cancer

AHI-1: a novel signaling protein and potential therapeutic target in human leukemia and brain disorders

Mitotic centromere-associated kinesin (MCAK): a potential cancer drug target

Regulation of glucose metabolism by p53: Emerging new roles for the tumor suppressor

MED12 exon 2 mutations are common in uterine leiomyomas from South African patients

CRIP1 expression is correlated with a favorable outcome and less metastases in osteosarcoma patients

Frizzled receptor 6 marks rare, highly tumourigenic stem-like cells in mouse and human neuroblastomas.

Antitumoral activity of allosteric inhibitors of Protein kinase CK2

Geminin overexpression induces mammary tumors via suppressing cytokinesis.

Cord blood stem cells revert glioma stem cell EMT by down regulating transcriptional activation of Sox2 and Twist1

Putting the brakes on mammary tumorigenesis: Loss of STAT1 predisposes to intraepithelial neoplasias

A Novel Dual Signaling Axis for NSP 5a3a induced apoptosis in Head and Neck Carcinoma

Annexin A2 is a novel Cellular Redox Regulatory Protein involved in Tumorigenesis

DNA-PKCS binding to p53 on the p21WAF1/CIP1 promoter blocks transcription resulting in cell death

Thyrocyte-specific inactivation of p53 and Pten results in anaplastic thyroid carcinomas faithfully recapitulating human tumors

Germline mutations in the oncogene EZH2 cause Weaver syndrome and increased human height

PIM kinase isoform specific regulation of MIG6 expression and EGFR signaling in prostate cancer cells

TAp73alpha protects small cell lung carcinoma cells from caspase-2 induced mitochondrial mediated apoptotic cell death

Phosphatase inhibitor, sodium stibogluconate, in combination with interferon (IFN) alpha 2b: phase I trials to identify pharmacodynamic and clinical effects

Overexpression of TWIST2 correlates with poor prognosis in Head and Neck Squamous Cell Carcinomas

Phospholipase PLA2G7, associated with aggressive prostate cancer, promotes prostate cancer cell migration and invasion and is inhibited by statins

Genome-wide analysis discloses reversal of the hypoxia-induced changes of gene expression in colon cancer cells by zinc supplementation

Mutant p53 uses p63 as a molecular chaperone to alter gene expression and induce a pro-invasive secretome

The suppression of FOXM1 and its targets in breast cancer xenograft tumors by siRNA

Characterization of the Human Folate Receptor Alpha Via Novel Antibody-Based Probes

A Modular Strategy to Prepare Multivalent Inhibitors of Prostate-Specific Membrane Antigen (PSMA)

Pooled shRNA screen for sensitizers to inhibition of the mitotic regulator polo-like kinase (PLK1)

Identification of a chrXq27.3 microRNA cluster associated with early relapse in advanced stage ovarian cancer patients

Selenium is a modulator of circadian clock that protects mice from the toxicity of a chemotherapeutic drug via upregulation of the core clock protein, BMAL1

Epigenetic regulation of Delta-Like1 controls Notch1 activation in gastric cancer

Finding cancer’s weakest link

Will PI3K pathway inhibitors be effective as single agents in patients with cancer?

AMPK in BCR-ABL expressing leukemias. Regulatory effects and therapeutic implications.

Is human cytomegalovirus a target in cancer therapy?

T cell- but not tumor cell-produced TGF-β1 promotes the development of spontaneous mammary cancer

NCI’s provocative questions on cancer: some answers to ignite discussion