Oncotarget

October 22, 2019

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About The Cover

The cover for issue 58 of Oncotarget features Figure 5, "Representative images of KLK6 and HMGA2 IHC staining in the surgical material of a colon cancer patient," by Chen, et al.

Table of Contents

Editorial

A-to-I RNA editing in leukemia stem cells - set ADAR1 on the radar

A-to-I RNA editing in leukemia stem cells - set ADAR1 on the radar

https://doi.org/10.18632/oncotarget.27261

Qingfei Jiang, Raymond Diep,  and Catriona Jamieson
6047-6048
PDF  |  How to cite

Research Papers

Preclinical analysis of human mesenchymal stem cells: tumor tropism and therapeutic efficiency of local HSV-TK suicide gene therapy in glioblastoma

Preclinical analysis of human mesenchymal stem cells: tumor tropism and therapeutic efficiency of local HSV-TK suicide gene therapy in glioblastoma

https://doi.org/10.18632/oncotarget.27071

Lasse Dührsen, Sophie Hartfuß, Daniela Hirsch, Sabine Geiger, Cecile L. Maire, Jan Sedlacik, Christine Guenther, Manfred Westphal, Katrin Lamszus, Felix G. Hermann,  and Nils Ole Schmidt
6049-6061
Abstract  |  PDF  |  Full Text  |  How to cite

Kallikrein 6 protease advances colon tumorigenesis via induction of the high mobility group A2 protein

Kallikrein 6 protease advances colon tumorigenesis via induction of the high mobility group A2 protein

https://doi.org/10.18632/oncotarget.27153

Hwudaurw Chen, Earlphia Sells, Ritu Pandey, Edward R. Abril, Chiu-Hsieh Hsu, Robert S. Krouse, Raymond B. Nagle, Georgios Pampalakis, Georgia Sotiropoulou,  and Natalia A. Ignatenko
6062-6078
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release  |  Podcast

Targeted photodynamic therapy treatment of in vitro A375 metastatic melanoma cells

Targeted photodynamic therapy treatment of in vitro A375 metastatic melanoma cells

https://doi.org/10.18632/oncotarget.27221

Channay Naidoo, Cherie Ann Kruger,  and Heidi Abrahamse
6079-6095
Abstract  |  PDF  |  Full Text  |  How to cite

Hyperpolarized in vivo pH imaging reveals grade-dependent acidification in prostate cancer

Hyperpolarized in vivo pH imaging reveals grade-dependent acidification in prostate cancer

https://doi.org/10.18632/oncotarget.27225

David E. Korenchan, Robert Bok, Renuka Sriram, Kristina Liu, Romelyn Delos Santos, Hecong Qin, Iryna Lobach, Natalie Korn, David M. Wilson, John Kurhanewicz,  and Robert R. Flavell
6096-6110
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Effect of Fms-like tyrosine kinase 3 (FLT3) ligand (FL) on antitumor activity of gilteritinib, a FLT3 inhibitor, in mice xenografted with FL-overexpressing cells

Effect of Fms-like tyrosine kinase 3 (FLT3) ligand (FL) on antitumor activity of gilteritinib, a FLT3 inhibitor, in mice xenografted with FL-overexpressing cells

https://doi.org/10.18632/oncotarget.27222

Tatsuya Kawase, Taisuke Nakazawa, Tomohiro Eguchi, Hirofumi Tsuzuki, Yoko Ueno, Yasushi Amano, Tomoyuki Suzuki, Masamichi Mori,  and Taku Yoshida
6111-6123
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The positivity rate of 68Gallium-PSMA-11 ligand PET/CT depends on the serum PSA-value in patients with biochemical recurrence of prostate cancer

The positivity rate of 68Gallium-PSMA-11 ligand PET/CT depends on the serum PSA-value in patients with biochemical recurrence of prostate cancer

https://doi.org/10.18632/oncotarget.27239

Manuela A. Hoffmann, Hans-Georg Buchholz, Helmut J. Wieler, Thomas Höfner, Jonas Müller-Hübenthal, Ludwin Trampert,  and Mathias Schreckenberger
6124-6137
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Adoptive cellular immunotherapy for refractory childhood cancers: a single center experience

Adoptive cellular immunotherapy for refractory childhood cancers: a single center experience

https://doi.org/10.18632/oncotarget.27242

Michael Merker, Michael Torsten Meister, Annekathrin Heinze, Andrea Jarisch, Jan Sörensen, Sabine Huenecke, Melanie Bremm, Claudia Cappel, Thomas Klingebiel, Peter Bader,  and Eva Rettinger
6138-6151
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Extramammary Paget disease shows differential expression of B7 family members B7-H3, B7-H4, PD-L1, PD-L2 and cancer/testis antigens NY-ESO-1 and MAGE-A

Extramammary Paget disease shows differential expression of B7 family members B7-H3, B7-H4, PD-L1, PD-L2 and cancer/testis antigens NY-ESO-1 and MAGE-A

https://doi.org/10.18632/oncotarget.27247

Maryam Pourmaleki, Jonathan H. Young, Nicholas D. Socci, Sarah Chiang, Marcia Edelweiss, Yanyun Li, Mianlei Zhang, Lev Roshal, Dennis S. Chi, Klaus J. Busam, Ingo K. Mellinghoff,  and Travis J. Hollmann
6152-6167
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Differential gene expression analysis of HNSCC tumors deciphered tobacco dependent and independent molecular signatures

Differential gene expression analysis of HNSCC tumors deciphered tobacco dependent and independent molecular signatures

https://doi.org/10.18632/oncotarget.27249

Inayatullah Shaikh, Afzal Ansari, Garima Ayachit, Monika Gandhi, Priyanka Sharma, Shivarudrappa Bhairappanavar, Chaitanya G. Joshi,  and Jayashankar Das
6168-6183
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Integrated copy number and miRNA expression analysis in triple negative breast cancer of Latin American patients

Integrated copy number and miRNA expression analysis in triple negative breast cancer of Latin American patients

https://doi.org/10.18632/oncotarget.27250

Bruna M. Sugita, Silma R. Pereira, Rodrigo C. de Almeida, Mandeep Gill, Akanksha Mahajan, Anju Duttargi, Saurabh Kirolikar, Paolo Fadda, Rubens S. de Lima, Cicero A. Urban, Kepher Makambi, Subha Madhavan, Simina M. Boca, Yuriy Gusev, Iglenir J. Cavalli, Enilze M.S.F. Ribeiro,  and Luciane R. Cavalli
6184-6203
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The predictive capability of immunohistochemistry and DNA sequencing for determining TP53 functional mutation status: a comparative study of 41 glioblastoma patients

The predictive capability of immunohistochemistry and DNA sequencing for determining TP53 functional mutation status: a comparative study of 41 glioblastoma patients

https://doi.org/10.18632/oncotarget.27252

Aarash K. Roshandel, Christopher M. Busch, Jennifer Van Mullekom, Joshua A. Cuoco, Cara M. Rogers, Lisa S. Apfel, Eric A. Marvin, Harald W. Sontheimer,  and Robyn A. Umans
6204-6218
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Preferential targeting of MCL-1 by a hydrocarbon-stapled BIM BH3 peptide

Preferential targeting of MCL-1 by a hydrocarbon-stapled BIM BH3 peptide

https://doi.org/10.18632/oncotarget.27262

Abbas Hadji, Greta K. Schmitt, Mathew R. Schnorenberg, Lauren Roach, Connie M. Hickey, Logan B. Leak, Matthew V. Tirrell,  and James L. LaBelle
6219-6233
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Biodistribution and efficacy of an anti-TENB2 antibody-drug conjugate in a patient-derived model of prostate cancer

Biodistribution and efficacy of an anti-TENB2 antibody-drug conjugate in a patient-derived model of prostate cancer

https://doi.org/10.18632/oncotarget.27263

C. Andrew Boswell, Daniela Bumbaca Yadav, Eduardo E. Mundo, Shang-Fan Yu, Jennifer Arca Lacap, Aimee Fourie-O’Donohue, Katherine R. Kozak, Gregory Z. Ferl, Crystal Zhang, Jason Ho, Sheila Ulufatu, Leslie A. Khawli,  and Kedan Lin
6234-6244
Abstract  |  PDF  |  Full Text  |  How to cite

Esophageal 3D organoids of MPV17-/- mouse model of mitochondrial DNA depletion show epithelial cell plasticity and telomere attrition

Esophageal 3D organoids of MPV17-/- mouse model of mitochondrial DNA depletion show epithelial cell plasticity and telomere attrition

https://doi.org/10.18632/oncotarget.27264

Manti Guha, Satish Srinivasan, Maura M. Sheehan, Takashi Kijima, Gordon Ruthel, Kelly Whelan, Koji Tanaka, Andres Klein-Szanto, Prasanna M. Chandramouleeswaran, Hiroshi Nakagawa,  and Narayan G. Avadhani
6245-6259
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Multiplatform profiling of pancreatic neuroendocrine tumors: Correlative analyses of clinicopathologic factors and identification of co-occurring pathogenic alterations

Multiplatform profiling of pancreatic neuroendocrine tumors: Correlative analyses of clinicopathologic factors and identification of co-occurring pathogenic alterations

https://doi.org/10.18632/oncotarget.27265

Jun Gong, Edik M. Blais, Joseph R. Bender, Michelle Guan, Veronica Placencio-Hickok, Emanuel F. Petricoin, Michael J. Pishvaian, Gary Gregory, Richard Tuli,  and Andrew E. Hendifar
6260-6268
Abstract  |  PDF  |  Full Text  |  How to cite

The phenanthrene derivative PJ34 exclusively eradicates human pancreatic cancer cells in xenografts

The phenanthrene derivative PJ34 exclusively eradicates human pancreatic cancer cells in xenografts

https://doi.org/10.18632/oncotarget.27268

Leonid Visochek, Dikla Atias, Itay Spektor, Asher Castiel, Talia Golan,  and Malka Cohen-Armon
6269-6282
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release  |  Podcast  |  Video Interview

Corrections

Correction: Hypericin targets osteoclast and prevents breast cancer-induced bone metastasis via NFATc1 signaling pathway

Correction: Hypericin targets osteoclast and prevents breast cancer-induced bone metastasis via NFATc1 signaling pathway

https://doi.org/10.18632/oncotarget.27273

Zhengxiao Ouyang, Xiaoning Guo, Xia Chen, Bo Liu, Qiang Zhang, Ziqing Yin, Zanjing Zhai, Xinhua Qu, Xuqiang Liu, Dan Peng, Yi Shen, Tang Liu,  and Qing Zhang
6283-6284
Correction  |  PDF  |  How to cite

Correction: Protein 4.1N acts as a potential tumor suppressor linking PP1 to JNK-c-Jun pathway regulation in NSCLC

Correction: Protein 4.1N acts as a potential tumor suppressor linking PP1 to JNK-c-Jun pathway regulation in NSCLC

https://doi.org/10.18632/oncotarget.27282

Zi Wang, Bianyin Ma, Hui Li, Xiaojuan Xiao, Weihua Zhou, Feng Liu, Bin Zhang, Min Zhu, Qin Yang, Yayue Zeng, Yang Sun, Shuming Sun, Yanpeng Wang, Yibin Zhang, Haibo Weng, Lixiang Chen, Mao Ye, Xiuli An,  and Jing Liu
6285-6285
Correction  |  PDF  |  How to cite


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